Result of FASTA (omim) for
pF1KE0234
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0234, 254 aa
1>>>pF1KE0234 254 - 254 aa - 254 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7695+/-0.000284; mu= 13.2111+/- 0.018
mean_var=71.6648+/-14.351, 0's: 0 Z-trim(118.5): 24 B-trim: 0 in 0/58
Lambda= 0.151503
statistics sampled from 31513 (31537) to 31513 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.37), width: 16
Scan time: 7.180
The best scores are: opt bits E(85289)
NP_001025062 (OMIM: 300567) phosphoglycerate mutas ( 254) 1727 385.9 3.9e-107
NP_002620 (OMIM: 172250) phosphoglycerate mutase 1 ( 254) 1637 366.2 3.2e-101
NP_000281 (OMIM: 261670,612931) phosphoglycerate m ( 253) 1371 308.0 1e-83
NP_001304008 (OMIM: 172250) phosphoglycerate mutas ( 239) 1339 301.0 1.2e-81
NP_954655 (OMIM: 222800,613896) bisphosphoglycerat ( 259) 977 221.9 8.8e-58
XP_011514829 (OMIM: 222800,613896) PREDICTED: bisp ( 259) 977 221.9 8.8e-58
NP_001715 (OMIM: 222800,613896) bisphosphoglycerat ( 259) 977 221.9 8.8e-58
NP_001280014 (OMIM: 222800,613896) bisphosphoglyce ( 259) 977 221.9 8.8e-58
>>NP_001025062 (OMIM: 300567) phosphoglycerate mutase 4 (254 aa)
initn: 1727 init1: 1727 opt: 1727 Z-score: 2044.5 bits: 385.9 E(85289): 3.9e-107
Smith-Waterman score: 1727; 100.0% identity (100.0% similar) in 254 aa overlap (1-254:1-254)
10 20 30 40 50 60
pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC
190 200 210 220 230 240
250
pF1KE0 KAIEAVAAQGKAKK
::::::::::::::
NP_001 KAIEAVAAQGKAKK
250
>>NP_002620 (OMIM: 172250) phosphoglycerate mutase 1 iso (254 aa)
initn: 1637 init1: 1637 opt: 1637 Z-score: 1938.1 bits: 366.2 E(85289): 3.2e-101
Smith-Waterman score: 1637; 95.7% identity (98.4% similar) in 254 aa overlap (1-254:1-254)
10 20 30 40 50 60
pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
::::::::::::::.:::::::: :::::::::::::::::::::::::::::::.::::
NP_002 MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR
:::::::::::::::::::::::::::::::: :: ::::::::::::::::::::::::
NP_002 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC
::::::::::.::.::.::::::::::::::::::::::::::::::::::::::::::
NP_002 VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR
190 200 210 220 230 240
250
pF1KE0 KAIEAVAAQGKAKK
::.:::::::::::
NP_002 KAMEAVAAQGKAKK
250
>>NP_000281 (OMIM: 261670,612931) phosphoglycerate mutas (253 aa)
initn: 1371 init1: 1371 opt: 1371 Z-score: 1624.0 bits: 308.0 E(85289): 1e-83
Smith-Waterman score: 1371; 77.9% identity (91.3% similar) in 253 aa overlap (1-253:1-253)
10 20 30 40 50 60
pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
::...::..:::::::: :::: :.::.:: : ::::::..:..:: .::::: :::
NP_000 MATHRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
::.:::::..::. ::::::::::::::::::::::::::::::::::: ::::::::.:
NP_000 KRAIRTLWAILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKR
.:::::. ::.:..:::.:::: : .::. :: :::::::::::::::::::: :::
NP_000 IPPPPMDEKHPYYNSISKERRYAGLKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVC
::::::::::.::.::.::.:..:::::::::::::::::.:.::: ::::::::::::
NP_000 VLIAAHGNSLRGIVKHLEGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVR
190 200 210 220 230 240
250
pF1KE0 KAIEAVAAQGKAKK
::.::::::::::
NP_000 KAMEAVAAQGKAK
250
>>NP_001304008 (OMIM: 172250) phosphoglycerate mutase 1 (239 aa)
initn: 1336 init1: 1336 opt: 1339 Z-score: 1586.5 bits: 301.0 E(85289): 1.2e-81
Smith-Waterman score: 1339; 93.1% identity (97.2% similar) in 216 aa overlap (39-254:26-239)
10 20 30 40 50 60
pF1KE0 IRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQKRVIRTLW
. .::. :::::::::.::::::.:::::
NP_001 MRHRYLASDCSPSFLPSLYHPSQMKQNAGQS--DAGYEFDICFTSVQKRAIRTLW
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 TVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 DHPFYSNISKDRRYADLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEGKRVLIAAHGN
:::::::::::::::::::::::: :: ::::::::::::::::::::::::::::::::
NP_001 DHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 SLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVCKAIEAVAA
::.::.::.:::::::::::::::::::::::::::::::::::::::::: ::.:::::
NP_001 SLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAA
180 190 200 210 220 230
250
pF1KE0 QGKAKK
::::::
NP_001 QGKAKK
>>NP_954655 (OMIM: 222800,613896) bisphosphoglycerate mu (259 aa)
initn: 979 init1: 577 opt: 977 Z-score: 1158.4 bits: 221.9 E(85289): 8.8e-58
Smith-Waterman score: 977; 52.0% identity (77.7% similar) in 256 aa overlap (1-254:1-256)
10 20 30 40 50 60
pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
:. :::...::::..:: :::: : : :. : :::. :. :. ..:::. .:::
NP_954 MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
.: :.: : .:. . : :.:: .:::::::::.: :::. . : .::: ::..:::::.
NP_954 NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 VPPPPMEPDHPFYSNISKDRRYA--DLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEG
: :::.: .::.:..: .:::: :. :::: :: ::.. : ::.:::.:.:.. .:
NP_954 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 KRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEET
: .::.::::: ... ::.::.:.: :....::::.::. :::.::. . : :::::.:.
NP_954 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEA
190 200 210 220 230 240
240 250
pF1KE0 VCKAIEAVAAQGKAKK
. ::. : :::.:.
NP_954 IQAAIKKVEDQGKVKQAKK
250
>>XP_011514829 (OMIM: 222800,613896) PREDICTED: bisphosp (259 aa)
initn: 979 init1: 577 opt: 977 Z-score: 1158.4 bits: 221.9 E(85289): 8.8e-58
Smith-Waterman score: 977; 52.0% identity (77.7% similar) in 256 aa overlap (1-254:1-256)
10 20 30 40 50 60
pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
:. :::...::::..:: :::: : : :. : :::. :. :. ..:::. .:::
XP_011 MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
.: :.: : .:. . : :.:: .:::::::::.: :::. . : .::: ::..:::::.
XP_011 NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 VPPPPMEPDHPFYSNISKDRRYA--DLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEG
: :::.: .::.:..: .:::: :. :::: :: ::.. : ::.:::.:.:.. .:
XP_011 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 KRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEET
: .::.::::: ... ::.::.:.: :....::::.::. :::.::. . : :::::.:.
XP_011 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEA
190 200 210 220 230 240
240 250
pF1KE0 VCKAIEAVAAQGKAKK
. ::. : :::.:.
XP_011 IQAAIKKVEDQGKVKQAKK
250
>>NP_001715 (OMIM: 222800,613896) bisphosphoglycerate mu (259 aa)
initn: 979 init1: 577 opt: 977 Z-score: 1158.4 bits: 221.9 E(85289): 8.8e-58
Smith-Waterman score: 977; 52.0% identity (77.7% similar) in 256 aa overlap (1-254:1-256)
10 20 30 40 50 60
pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
:. :::...::::..:: :::: : : :. : :::. :. :. ..:::. .:::
NP_001 MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
.: :.: : .:. . : :.:: .:::::::::.: :::. . : .::: ::..:::::.
NP_001 NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 VPPPPMEPDHPFYSNISKDRRYA--DLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEG
: :::.: .::.:..: .:::: :. :::: :: ::.. : ::.:::.:.:.. .:
NP_001 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 KRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEET
: .::.::::: ... ::.::.:.: :....::::.::. :::.::. . : :::::.:.
NP_001 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEA
190 200 210 220 230 240
240 250
pF1KE0 VCKAIEAVAAQGKAKK
. ::. : :::.:.
NP_001 IQAAIKKVEDQGKVKQAKK
250
>>NP_001280014 (OMIM: 222800,613896) bisphosphoglycerate (259 aa)
initn: 979 init1: 577 opt: 977 Z-score: 1158.4 bits: 221.9 E(85289): 8.8e-58
Smith-Waterman score: 977; 52.0% identity (77.7% similar) in 256 aa overlap (1-254:1-256)
10 20 30 40 50 60
pF1KE0 MAAYKLVLIRHGESTWNLENRFSCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSVQ
:. :::...::::..:: :::: : : :. : :::. :. :. ..:::. .:::
NP_001 MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KRVIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
.: :.: : .:. . : :.:: .:::::::::.: :::. . : .::: ::..:::::.
NP_001 NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 VPPPPMEPDHPFYSNISKDRRYA--DLTEDQLPSYESPKDTIARALPFWNEEIVPQIKEG
: :::.: .::.:..: .:::: :. :::: :: ::.. : ::.:::.:.:.. .:
NP_001 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 KRVLIAAHGNSLQGIAKHVEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEET
: .::.::::: ... ::.::.:.: :....::::.::. :::.::. . : :::::.:.
NP_001 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEA
190 200 210 220 230 240
240 250
pF1KE0 VCKAIEAVAAQGKAKK
. ::. : :::.:.
NP_001 IQAAIKKVEDQGKVKQAKK
250
254 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:06:43 2016 done: Thu Nov 3 20:06:44 2016
Total Scan time: 7.180 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]