Result of FASTA (omim) for
pF1KE0118
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0118, 195 aa
1>>>pF1KE0118 195 - 195 aa - 195 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9396+/-0.000377; mu= 14.8077+/- 0.023
mean_var=56.6740+/-11.667, 0's: 0 Z-trim(111.7): 10 B-trim: 0 in 0/51
Lambda= 0.170366
statistics sampled from 20308 (20318) to 20308 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.238), width: 16
Scan time: 5.630
The best scores are: opt bits E(85289)
NP_115649 (OMIM: 612988,612989) transmembrane prot ( 195) 1267 319.5 2.2e-87
NP_001231664 (OMIM: 612988,612989) transmembrane p ( 125) 830 212.0 3.2e-55
NP_001180467 (OMIM: 252010,615533) complex I assem ( 200) 287 78.6 7.2e-15
XP_011543467 (OMIM: 252010,615533) PREDICTED: comp ( 200) 287 78.6 7.2e-15
NP_001243475 (OMIM: 252010,615533) complex I assem ( 200) 287 78.6 7.2e-15
NP_001180466 (OMIM: 252010,615533) complex I assem ( 210) 287 78.6 7.5e-15
NP_001243476 (OMIM: 252010,615533) complex I assem ( 184) 286 78.4 7.9e-15
NP_060950 (OMIM: 252010,615533) complex I assembly ( 230) 287 78.7 8e-15
>>NP_115649 (OMIM: 612988,612989) transmembrane protein (195 aa)
initn: 1267 init1: 1267 opt: 1267 Z-score: 1689.9 bits: 319.5 E(85289): 2.2e-87
Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KE0 MENHKSNNKENITIVDISRKINQLPEAERNLLENGSVYVGLNAALCGLIANSLFRRILNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MENHKSNNKENITIVDISRKINQLPEAERNLLENGSVYVGLNAALCGLIANSLFRRILNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 TKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLTGLVIGGLYPVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLTGLVIGGLYPVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMFSAYLGSEQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMFSAYLGSEQYKL
130 140 150 160 170 180
190
pF1KE0 LIKALQLSEPGKEIH
:::::::::::::::
NP_115 LIKALQLSEPGKEIH
190
>>NP_001231664 (OMIM: 612988,612989) transmembrane prote (125 aa)
initn: 830 init1: 830 opt: 830 Z-score: 1112.4 bits: 212.0 E(85289): 3.2e-55
Smith-Waterman score: 830; 100.0% identity (100.0% similar) in 125 aa overlap (71-195:1-125)
50 60 70 80 90 100
pF1KE0 LNAALCGLIANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCET
::::::::::::::::::::::::::::::
NP_001 MAGIPFLTTDLTYRCFVSFPLNTGDLDCET
10 20 30
110 120 130 140 150 160
pF1KE0 CTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKML
40 50 60 70 80 90
170 180 190
pF1KE0 FPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH
:::::::::::::::::::::::::::::::::::
NP_001 FPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH
100 110 120
>>NP_001180467 (OMIM: 252010,615533) complex I assembly (200 aa)
initn: 258 init1: 173 opt: 287 Z-score: 388.0 bits: 78.6 E(85289): 7.2e-15
Smith-Waterman score: 287; 30.2% identity (64.2% similar) in 179 aa overlap (9-186:19-194)
10 20 30 40
pF1KE0 MENHKSNNKENITIVDISRKINQL-PEAERNLLENGSVYVGLNAALCGLI
.. ..: : .... : : .:. . .. : .:.. :..
NP_001 MAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRKEMTQNIYQMAT--FGTTAGFSGIF
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 ANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLT
.: :::: ..: . . . .: .:::.: .: . :: : . ... :.: . ::.:
NP_001 SNFLFRRCFKVKHDALKTYASLATLPFLSTVVTDKLFVIDALYSDNISKENC-VFRSSLI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 GLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMF
:.: : .:: ::. :: ::..:... :: :: .: .:. . .. : .:...: ::
NP_001 GIVCGVFYPSSLAFTKNGRLATKYHTVPLPPKGRVLIHWMTLCQTQMKLMAIPLVFQIMF
120 130 140 150 160 170
170 180 190
pF1KE0 SAYLGSEQYKLLIKALQLSEPGKEIH
. : .: .. ..:.
NP_001 GILNGLYHYAVFEETLEKTIHEE
180 190 200
>>XP_011543467 (OMIM: 252010,615533) PREDICTED: complex (200 aa)
initn: 258 init1: 173 opt: 287 Z-score: 388.0 bits: 78.6 E(85289): 7.2e-15
Smith-Waterman score: 287; 30.2% identity (64.2% similar) in 179 aa overlap (9-186:19-194)
10 20 30 40
pF1KE0 MENHKSNNKENITIVDISRKINQL-PEAERNLLENGSVYVGLNAALCGLI
.. ..: : .... : : .:. . .. : .:.. :..
XP_011 MAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRKEMTQNIYQMAT--FGTTAGFSGIF
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 ANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLT
.: :::: ..: . . . .: .:::.: .: . :: : . ... :.: . ::.:
XP_011 SNFLFRRCFKVKHDALKTYASLATLPFLSTVVTDKLFVIDALYSDNISKENC-VFRSSLI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 GLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMF
:.: : .:: ::. :: ::..:... :: :: .: .:. . .. : .:...: ::
XP_011 GIVCGVFYPSSLAFTKNGRLATKYHTVPLPPKGRVLIHWMTLCQTQMKLMAIPLVFQIMF
120 130 140 150 160 170
170 180 190
pF1KE0 SAYLGSEQYKLLIKALQLSEPGKEIH
. : .: .. ..:.
XP_011 GILNGLYHYAVFEETLEKTIHEE
180 190 200
>>NP_001243475 (OMIM: 252010,615533) complex I assembly (200 aa)
initn: 258 init1: 173 opt: 287 Z-score: 388.0 bits: 78.6 E(85289): 7.2e-15
Smith-Waterman score: 287; 30.2% identity (64.2% similar) in 179 aa overlap (9-186:19-194)
10 20 30 40
pF1KE0 MENHKSNNKENITIVDISRKINQL-PEAERNLLENGSVYVGLNAALCGLI
.. ..: : .... : : .:. . .. : .:.. :..
NP_001 MAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRKEMTQNIYQMAT--FGTTAGFSGIF
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 ANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLT
.: :::: ..: . . . .: .:::.: .: . :: : . ... :.: . ::.:
NP_001 SNFLFRRCFKVKHDALKTYASLATLPFLSTVVTDKLFVIDALYSDNISKENC-VFRSSLI
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 GLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMF
:.: : .:: ::. :: ::..:... :: :: .: .:. . .. : .:...: ::
NP_001 GIVCGVFYPSSLAFTKNGRLATKYHTVPLPPKGRVLIHWMTLCQTQMKLMAIPLVFQIMF
120 130 140 150 160 170
170 180 190
pF1KE0 SAYLGSEQYKLLIKALQLSEPGKEIH
. : .: .. ..:.
NP_001 GILNGLYHYAVFEETLEKTIHEE
180 190 200
>>NP_001180466 (OMIM: 252010,615533) complex I assembly (210 aa)
initn: 258 init1: 173 opt: 287 Z-score: 387.7 bits: 78.6 E(85289): 7.5e-15
Smith-Waterman score: 287; 30.2% identity (64.2% similar) in 179 aa overlap (9-186:29-204)
10 20 30
pF1KE0 MENHKSNNKENITIVDISRKINQL-PEAERNLLENGSVYV
.. ..: : .... : : .:. . ..
NP_001 MLNKILKVFKMAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRKEMTQNIYQMAT--F
10 20 30 40 50
40 50 60 70 80 90
pF1KE0 GLNAALCGLIANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLDCE
: .:.. :...: :::: ..: . . . .: .:::.: .: . :: : . ... :
NP_001 GTTAGFSGIFSNFLFRRCFKVKHDALKTYASLATLPFLSTVVTDKLFVIDALYSDNISKE
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE0 TCTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFRKM
.: . ::.: :.: : .:: ::. :: ::..:... :: :: .: .:. . .. :
NP_001 NC-VFRSSLIGIVCGVFYPSSLAFTKNGRLATKYHTVPLPPKGRVLIHWMTLCQTQMKLM
120 130 140 150 160 170
160 170 180 190
pF1KE0 LFPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH
.:...: ::. : .: .. ..:.
NP_001 AIPLVFQIMFGILNGLYHYAVFEETLEKTIHEE
180 190 200 210
>>NP_001243476 (OMIM: 252010,615533) complex I assembly (184 aa)
initn: 258 init1: 173 opt: 286 Z-score: 387.2 bits: 78.4 E(85289): 7.9e-15
Smith-Waterman score: 286; 33.3% identity (66.0% similar) in 147 aa overlap (40-186:33-178)
10 20 30 40 50 60
pF1KE0 ENITIVDISRKINQLPEAERNLLENGSVYVGLNAALCGLIANSLFRRILNVTKARIAAGL
: .:.. :...: :::: ..: . . .
NP_001 LGLSQGIQVWCRWELRKRPRTQNIYQMATFGTTAGFSGIFSNFLFRRCFKVKHDALKTYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PMAGIPFLTTDLTYRCFVSFPLNTGDLDCETCTITRSGLTGLVIGGLYPVFLAIPVNGGL
.: .:::.: .: . :: : . ... :.: . ::.: :.: : .:: ::. :: :
NP_001 SLATLPFLSTVVTDKLFVIDALYSDNISKENC-VFRSSLIGIVCGVFYPSSLAFTKNGRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 AARYQSALLPHKGNILSYWIRTSKPVFRKMLFPILLQTMFSAYLGSEQYKLLIKALQLSE
:..:... :: :: .: .:. . .. : .:...: ::. : .: .. ..:.
NP_001 ATKYHTVPLPPKGRVLIHWMTLCQTQMKLMAIPLVFQIMFGILNGLYHYAVFEETLEKTI
130 140 150 160 170 180
190
pF1KE0 PGKEIH
NP_001 HEE
>>NP_060950 (OMIM: 252010,615533) complex I assembly fac (230 aa)
initn: 258 init1: 173 opt: 287 Z-score: 387.1 bits: 78.7 E(85289): 8e-15
Smith-Waterman score: 287; 30.2% identity (64.2% similar) in 179 aa overlap (9-186:49-224)
10 20 30
pF1KE0 MENHKSNNKENITIVDISRKINQL-PEAERNLLENGSV
.. ..: : .... : : .:. . ..
NP_060 PVGTEEAPKVFKMAASMHGQPSPSLEDAKLRRPMVIEIIEKNFDYLRKEMTQNIYQMAT-
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE0 YVGLNAALCGLIANSLFRRILNVTKARIAAGLPMAGIPFLTTDLTYRCFVSFPLNTGDLD
: .:.. :...: :::: ..: . . . .: .:::.: .: . :: : . ...
NP_060 -FGTTAGFSGIFSNFLFRRCFKVKHDALKTYASLATLPFLSTVVTDKLFVIDALYSDNIS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE0 CETCTITRSGLTGLVIGGLYPVFLAIPVNGGLAARYQSALLPHKGNILSYWIRTSKPVFR
:.: . ::.: :.: : .:: ::. :: ::..:... :: :: .: .:. . ..
NP_060 KENC-VFRSSLIGIVCGVFYPSSLAFTKNGRLATKYHTVPLPPKGRVLIHWMTLCQTQMK
140 150 160 170 180 190
160 170 180 190
pF1KE0 KMLFPILLQTMFSAYLGSEQYKLLIKALQLSEPGKEIH
: .:...: ::. : .: .. ..:.
NP_060 LMAIPLVFQIMFGILNGLYHYAVFEETLEKTIHEE
200 210 220 230
195 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:17:51 2016 done: Fri Nov 4 02:17:52 2016
Total Scan time: 5.630 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]