Result of FASTA (omim) for
pF1KE0058
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0058, 759 aa
1>>>pF1KE0058 759 - 759 aa - 759 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.6645+/-0.000526; mu= -26.2380+/- 0.033
mean_var=709.8771+/-147.577, 0's: 0 Z-trim(122.7): 151 B-trim: 0 in 0/62
Lambda= 0.048137
statistics sampled from 41184 (41348) to 41184 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.485), width: 16
Scan time: 13.920
The best scores are: opt bits E(85289)
NP_060556 (OMIM: 605295) fidgetin isoform 1 [Homo ( 759) 5095 369.5 3e-101
XP_016859908 (OMIM: 605295) PREDICTED: fidgetin is ( 785) 5050 366.3 2.7e-100
XP_011509691 (OMIM: 605295) PREDICTED: fidgetin is ( 785) 5050 366.3 2.7e-100
NP_001308754 (OMIM: 605295) fidgetin isoform 2 [Ho ( 748) 5031 365.0 6.4e-100
NP_001333487 (OMIM: 615383) fidgetin-like protein ( 563) 1303 106.0 4.5e-22
NP_001333488 (OMIM: 615383) fidgetin-like protein ( 563) 1303 106.0 4.5e-22
NP_001274425 (OMIM: 615383) fidgetin-like protein ( 563) 1303 106.0 4.5e-22
NP_001274423 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001333492 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001274421 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001333491 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001333490 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001274422 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_071399 (OMIM: 615383) fidgetin-like protein 1 i ( 674) 1303 106.1 5.1e-22
XP_011513772 (OMIM: 615383) PREDICTED: fidgetin-li ( 674) 1303 106.1 5.1e-22
XP_016867990 (OMIM: 615383) PREDICTED: fidgetin-li ( 674) 1303 106.1 5.1e-22
NP_001333489 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001036227 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001333494 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001274424 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
NP_001333493 (OMIM: 615383) fidgetin-like protein ( 674) 1303 106.1 5.1e-22
XP_016860266 (OMIM: 182601,604277) PREDICTED: spas ( 583) 871 76.0 4.9e-13
NP_955468 (OMIM: 182601,604277) spastin isoform 2 ( 584) 869 75.9 5.4e-13
XP_005264573 (OMIM: 182601,604277) PREDICTED: spas ( 615) 807 71.6 1.1e-11
NP_055761 (OMIM: 182601,604277) spastin isoform 1 ( 616) 807 71.6 1.1e-11
XP_016860267 (OMIM: 182601,604277) PREDICTED: spas ( 519) 703 64.3 1.5e-09
XP_011531369 (OMIM: 182601,604277) PREDICTED: spas ( 551) 641 60.0 3e-08
XP_011524570 (OMIM: 609983) PREDICTED: vacuolar pr ( 418) 580 55.7 4.7e-07
NP_004860 (OMIM: 609983) vacuolar protein sorting- ( 444) 580 55.7 4.9e-07
NP_037377 (OMIM: 609982) vacuolar protein sorting- ( 437) 579 55.6 5.1e-07
XP_006722645 (OMIM: 609983) PREDICTED: vacuolar pr ( 326) 569 54.8 6.6e-07
XP_005266861 (OMIM: 606696) PREDICTED: katanin p60 ( 491) 571 55.1 8.1e-07
NP_008975 (OMIM: 606696) katanin p60 ATPase-contai ( 491) 571 55.1 8.1e-07
XP_016865696 (OMIM: 606696) PREDICTED: katanin p60 ( 491) 571 55.1 8.1e-07
XP_016865699 (OMIM: 606696) PREDICTED: katanin p60 ( 491) 571 55.1 8.1e-07
XP_005258418 (OMIM: 614697) PREDICTED: katanin p60 ( 427) 565 54.7 9.7e-07
XP_016881520 (OMIM: 614697) PREDICTED: katanin p60 ( 427) 565 54.7 9.7e-07
XP_016881519 (OMIM: 614697) PREDICTED: katanin p60 ( 465) 565 54.7 1e-06
NP_112593 (OMIM: 614697) katanin p60 ATPase-contai ( 466) 565 54.7 1e-06
XP_006722617 (OMIM: 614697) PREDICTED: katanin p60 ( 538) 565 54.7 1.2e-06
XP_005258415 (OMIM: 614697) PREDICTED: katanin p60 ( 563) 565 54.8 1.2e-06
XP_005258414 (OMIM: 614697) PREDICTED: katanin p60 ( 564) 565 54.8 1.2e-06
XP_016876280 (OMIM: 614764) PREDICTED: katanin p60 ( 322) 546 53.2 2e-06
XP_016876281 (OMIM: 614764) PREDICTED: katanin p60 ( 322) 546 53.2 2e-06
XP_016876282 (OMIM: 614764) PREDICTED: katanin p60 ( 322) 546 53.2 2e-06
NP_115492 (OMIM: 614764) katanin p60 ATPase-contai ( 490) 546 53.4 2.7e-06
NP_001014402 (OMIM: 614764) katanin p60 ATPase-con ( 490) 546 53.4 2.7e-06
XP_005266631 (OMIM: 614764) PREDICTED: katanin p60 ( 490) 546 53.4 2.7e-06
XP_011538604 (OMIM: 614452) PREDICTED: ATPase fami ( 303) 489 49.3 2.9e-05
XP_005270309 (OMIM: 614452) PREDICTED: ATPase fami ( 361) 489 49.3 3.3e-05
>>NP_060556 (OMIM: 605295) fidgetin isoform 1 [Homo sapi (759 aa)
initn: 5095 init1: 5095 opt: 5095 Z-score: 1938.8 bits: 369.5 E(85289): 3e-101
Smith-Waterman score: 5095; 100.0% identity (100.0% similar) in 759 aa overlap (1-759:1-759)
10 20 30 40 50 60
pF1KE0 MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 MNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 TPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 RGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 IIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQ
670 680 690 700 710 720
730 740 750
pF1KE0 LRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
:::::::::::::::::::::::::::::::::::::::
NP_060 LRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
730 740 750
>>XP_016859908 (OMIM: 605295) PREDICTED: fidgetin isofor (785 aa)
initn: 5050 init1: 5050 opt: 5050 Z-score: 1921.7 bits: 366.3 E(85289): 2.7e-100
Smith-Waterman score: 5050; 100.0% identity (100.0% similar) in 751 aa overlap (9-759:35-785)
10 20 30
pF1KE0 MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHK
::::::::::::::::::::::::::::::
XP_016 LWNDLLCLCHIVLRREHYTVLTRCSVPNKRGLKMQWTPEHAQWPEQHFDITSTTRSPAHK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 VEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 VNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 TEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 LLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 IPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 GQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 LTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVD
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE0 EQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTAL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE0 PRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE0 PSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDE
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE0 SLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE0 EAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCS
730 740 750 760 770 780
pF1KE0 Q
:
XP_016 Q
>>XP_011509691 (OMIM: 605295) PREDICTED: fidgetin isofor (785 aa)
initn: 5050 init1: 5050 opt: 5050 Z-score: 1921.7 bits: 366.3 E(85289): 2.7e-100
Smith-Waterman score: 5050; 100.0% identity (100.0% similar) in 751 aa overlap (9-759:35-785)
10 20 30
pF1KE0 MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHK
::::::::::::::::::::::::::::::
XP_011 LWNDLLCLCHIVLRREHYTVLTRCSVPNKRGLKMQWTPEHAQWPEQHFDITSTTRSPAHK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 VEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 VNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 TEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 LLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 IPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 GQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 LTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVD
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE0 EQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTAL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE0 PRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQ
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE0 PSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDE
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE0 SLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE0 EAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCS
730 740 750 760 770 780
pF1KE0 Q
:
XP_011 Q
>>NP_001308754 (OMIM: 605295) fidgetin isoform 2 [Homo s (748 aa)
initn: 5031 init1: 5031 opt: 5031 Z-score: 1914.9 bits: 365.0 E(85289): 6.4e-100
Smith-Waterman score: 5031; 100.0% identity (100.0% similar) in 748 aa overlap (12-759:1-748)
10 20 30 40 50 60
pF1KE0 MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDIS
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDIS
10 20 30 40
70 80 90 100 110 120
pF1KE0 ALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 MNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 PSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 TPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTN
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE0 RGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFG
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE0 KYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE0 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE0 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE0 PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQ
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE0 IIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQ
650 660 670 680 690 700
730 740 750
pF1KE0 LRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
:::::::::::::::::::::::::::::::::::::::
NP_001 LRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
710 720 730 740
>>NP_001333487 (OMIM: 615383) fidgetin-like protein 1 is (563 aa)
initn: 1274 init1: 1183 opt: 1303 Z-score: 517.3 bits: 106.0 E(85289): 4.5e-22
Smith-Waterman score: 1306; 45.6% identity (76.2% similar) in 445 aa overlap (317-759:145-563)
290 300 310 320 330 340
pF1KE0 PTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQS
.::.:: :.: .:. ..
NP_001 KENHSSAKENIGLNVFLSNQSCFPAACENPQRKSFY--GSGTIDA------------LSN
120 130 140 150 160
350 360 370 380 390 400
pF1KE0 PMYRMPDNSISNTNRGNGFDRSAETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYS
:. :. . .. :: : ::: .:: .:. . .::.:. : .:: . ::.
NP_001 PIL----NKACSKTEDNG---PKEDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYG
170 180 190 200 210
410 420 430 440 450 460
pF1KE0 TAKNSLG-SRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNT
.:.::: ::: .::.. :. .. : :. .. : : : : :::.:::
NP_001 GVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNL
220 230 240 250 260
470 480 490 500 510 520
pF1KE0 DTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILL
. ..:.:. :::. .::::.:.::::....::.::: :.::.:: : :.:: . :..:::
NP_001 EPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILL
270 280 290 300 310 320
530 540 550 560 570 580
pF1KE0 FGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFV
::: ::::::.:.::::: :::::.:..:.:..::.::.::...: : ::::.::.:::.
NP_001 FGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFI
330 340 350 360 370 380
590 600 610 620 630 640
pF1KE0 SDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYF
..:: :::.. . :: :..::::.::: . ::.::.:.:. ::..:.::::. :: .
NP_001 DEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRL
390 400 410 420 430 440
650 660 670 680 690 700
pF1KE0 MKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGP
.::: ::::...::.::...:.:... ::...:. .::....::: :...::.:: .::
NP_001 VKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGP
450 460 470 480 490 500
710 720 730 740 750
pF1KE0 LHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
.... ..:...: :.:.::..: :::::: ..::.: :.:..: .::: :::..
NP_001 IRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK
510 520 530 540 550 560
>>NP_001333488 (OMIM: 615383) fidgetin-like protein 1 is (563 aa)
initn: 1274 init1: 1183 opt: 1303 Z-score: 517.3 bits: 106.0 E(85289): 4.5e-22
Smith-Waterman score: 1306; 45.6% identity (76.2% similar) in 445 aa overlap (317-759:145-563)
290 300 310 320 330 340
pF1KE0 PTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQS
.::.:: :.: .:. ..
NP_001 KENHSSAKENIGLNVFLSNQSCFPAACENPQRKSFY--GSGTIDA------------LSN
120 130 140 150 160
350 360 370 380 390 400
pF1KE0 PMYRMPDNSISNTNRGNGFDRSAETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYS
:. :. . .. :: : ::: .:: .:. . .::.:. : .:: . ::.
NP_001 PIL----NKACSKTEDNG---PKEDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYG
170 180 190 200 210
410 420 430 440 450 460
pF1KE0 TAKNSLG-SRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNT
.:.::: ::: .::.. :. .. : :. .. : : : : :::.:::
NP_001 GVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNL
220 230 240 250 260
470 480 490 500 510 520
pF1KE0 DTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILL
. ..:.:. :::. .::::.:.::::....::.::: :.::.:: : :.:: . :..:::
NP_001 EPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILL
270 280 290 300 310 320
530 540 550 560 570 580
pF1KE0 FGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFV
::: ::::::.:.::::: :::::.:..:.:..::.::.::...: : ::::.::.:::.
NP_001 FGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFI
330 340 350 360 370 380
590 600 610 620 630 640
pF1KE0 SDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYF
..:: :::.. . :: :..::::.::: . ::.::.:.:. ::..:.::::. :: .
NP_001 DEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRL
390 400 410 420 430 440
650 660 670 680 690 700
pF1KE0 MKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGP
.::: ::::...::.::...:.:... ::...:. .::....::: :...::.:: .::
NP_001 VKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGP
450 460 470 480 490 500
710 720 730 740 750
pF1KE0 LHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
.... ..:...: :.:.::..: :::::: ..::.: :.:..: .::: :::..
NP_001 IRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK
510 520 530 540 550 560
>>NP_001274425 (OMIM: 615383) fidgetin-like protein 1 is (563 aa)
initn: 1274 init1: 1183 opt: 1303 Z-score: 517.3 bits: 106.0 E(85289): 4.5e-22
Smith-Waterman score: 1306; 45.6% identity (76.2% similar) in 445 aa overlap (317-759:145-563)
290 300 310 320 330 340
pF1KE0 PTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQS
.::.:: :.: .:. ..
NP_001 KENHSSAKENIGLNVFLSNQSCFPAACENPQRKSFY--GSGTIDA------------LSN
120 130 140 150 160
350 360 370 380 390 400
pF1KE0 PMYRMPDNSISNTNRGNGFDRSAETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYS
:. :. . .. :: : ::: .:: .:. . .::.:. : .:: . ::.
NP_001 PIL----NKACSKTEDNG---PKEDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYG
170 180 190 200 210
410 420 430 440 450 460
pF1KE0 TAKNSLG-SRSSESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNT
.:.::: ::: .::.. :. .. : :. .. : : : : :::.:::
NP_001 GVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNL
220 230 240 250 260
470 480 490 500 510 520
pF1KE0 DTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILL
. ..:.:. :::. .::::.:.::::....::.::: :.::.:: : :.:: . :..:::
NP_001 EPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILL
270 280 290 300 310 320
530 540 550 560 570 580
pF1KE0 FGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFV
::: ::::::.:.::::: :::::.:..:.:..::.::.::...: : ::::.::.:::.
NP_001 FGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFI
330 340 350 360 370 380
590 600 610 620 630 640
pF1KE0 SDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYF
..:: :::.. . :: :..::::.::: . ::.::.:.:. ::..:.::::. :: .
NP_001 DEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRL
390 400 410 420 430 440
650 660 670 680 690 700
pF1KE0 MKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGP
.::: ::::...::.::...:.:... ::...:. .::....::: :...::.:: .::
NP_001 VKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGP
450 460 470 480 490 500
710 720 730 740 750
pF1KE0 LHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
.... ..:...: :.:.::..: :::::: ..::.: :.:..: .::: :::..
NP_001 IRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK
510 520 530 540 550 560
>>NP_001274423 (OMIM: 615383) fidgetin-like protein 1 is (674 aa)
initn: 1481 init1: 1183 opt: 1303 Z-score: 516.2 bits: 106.1 E(85289): 5.1e-22
Smith-Waterman score: 1498; 38.0% identity (66.4% similar) in 744 aa overlap (19-759:12-674)
10 20 30 40 50
pF1KE0 MISSTSVYGLKMQWTPEHAQWPEQHFDITS-TTRSPAHKVEAYRGHLQRTYQYAWANDDI
..: ...: ::: .: :..:::... : ::::::..:
NP_001 MQTSSSRSVHLSEWQKNYFAITSGICTGP--KADAYRAQILRI-QYAWANSEI
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 SALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVY
: . :..:.::::::::.:... . :.::... :.......:. :: .:. . :.
NP_001 SQVCATKLFKKYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 PMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAG
:. : .. :.: .: : :: .:. : . :. . :..: .:::
NP_001 KMSSVQKMMQAGKKFKDSLLEPALASVVIHKE---ATVFDLPKFS--VCGS---------
120 130 140 150
180 190 200 210 220 230
pF1KE0 LPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGT
::: :.. :. .: :. . :. ::: :: .: .
NP_001 --SQESDSLPNSA--HDRDRTQDF-----PESNRLK---LLQNAQPP-----MVTN----
160 170 180 190
240 250 260 270 280 290
pF1KE0 SNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHG
.. . :. : : :: . . : : ... . : . .
NP_001 ---TARTCPTFSAP----VGESATAKFHVTP----LFGNVKKENHSSAKENIGLNVFLSN
200 210 220 230 240
300 310 320 330 340 350
pF1KE0 LTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNT
. . :.: : .::.:: :.: .:. ..:. :. .
NP_001 QSCF-PAACENP-----QRKSFY--GSGTIDA------------LSNPIL----NKACSK
250 260 270 280
360 370 380 390 400 410
pF1KE0 NRGNGFDRSAETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLG-SRSSE
.. :: : ::: .:: .:. . .::.:. : .:: . ::. .:.::: :::
NP_001 TEDNG---PKEDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYGGVKKSLGASRSRG
290 300 310 320 330
420 430 440 450 460 470
pF1KE0 SFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEII
.::.. :. .. : :. .. : : : : :::.::: . ..:.:. :::.
NP_001 ILGKFVPPIPKQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNLEPKMIELIMNEIM
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE0 TQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGR
.::::.:.::::....::.::: :.::.:: : :.:: . :..:::::: ::::::.:.
NP_001 DHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGK
400 410 420 430 440 450
540 550 560 570 580 590
pF1KE0 CIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNE
::::: :::::.:..:.:..::.::.::...: : ::::.::.:::...:: :::.. .
NP_001 CIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDG
460 470 480 490 500 510
600 610 620 630 640 650
pF1KE0 EHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTA
:: :..::::.::: . ::.::.:.:. ::..:.::::. :: ..::: ::::...:
NP_001 EHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASA
520 530 540 550 560 570
660 670 680 690 700 710
pF1KE0 RHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIM
:.::...:.:... ::...:. .::....::: :...::.:: .::.... ..:...:
NP_001 RKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATIT
580 590 600 610 620 630
720 730 740 750
pF1KE0 PSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
:.:.::..: :::::: ..::.: :.:..: .::: :::..
NP_001 PDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK
640 650 660 670
>>NP_001333492 (OMIM: 615383) fidgetin-like protein 1 is (674 aa)
initn: 1481 init1: 1183 opt: 1303 Z-score: 516.2 bits: 106.1 E(85289): 5.1e-22
Smith-Waterman score: 1498; 38.0% identity (66.4% similar) in 744 aa overlap (19-759:12-674)
10 20 30 40 50
pF1KE0 MISSTSVYGLKMQWTPEHAQWPEQHFDITS-TTRSPAHKVEAYRGHLQRTYQYAWANDDI
..: ...: ::: .: :..:::... : ::::::..:
NP_001 MQTSSSRSVHLSEWQKNYFAITSGICTGP--KADAYRAQILRI-QYAWANSEI
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 SALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVY
: . :..:.::::::::.:... . :.::... :.......:. :: .:. . :.
NP_001 SQVCATKLFKKYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 PMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAG
:. : .. :.: .: : :: .:. : . :. . :..: .:::
NP_001 KMSSVQKMMQAGKKFKDSLLEPALASVVIHKE---ATVFDLPKFS--VCGS---------
120 130 140 150
180 190 200 210 220 230
pF1KE0 LPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGT
::: :.. :. .: :. . :. ::: :: .: .
NP_001 --SQESDSLPNSA--HDRDRTQDF-----PESNRLK---LLQNAQPP-----MVTN----
160 170 180 190
240 250 260 270 280 290
pF1KE0 SNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHG
.. . :. : : :: . . : : ... . : . .
NP_001 ---TARTCPTFSAP----VGESATAKFHVTP----LFGNVKKENHSSAKENIGLNVFLSN
200 210 220 230 240
300 310 320 330 340 350
pF1KE0 LTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNT
. . :.: : .::.:: :.: .:. ..:. :. .
NP_001 QSCF-PAACENP-----QRKSFY--GSGTIDA------------LSNPIL----NKACSK
250 260 270 280
360 370 380 390 400 410
pF1KE0 NRGNGFDRSAETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLG-SRSSE
.. :: : ::: .:: .:. . .::.:. : .:: . ::. .:.::: :::
NP_001 TEDNG---PKEDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYGGVKKSLGASRSRG
290 300 310 320 330
420 430 440 450 460 470
pF1KE0 SFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEII
.::.. :. .. : :. .. : : : : :::.::: . ..:.:. :::.
NP_001 ILGKFVPPIPKQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNLEPKMIELIMNEIM
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE0 TQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGR
.::::.:.::::....::.::: :.::.:: : :.:: . :..:::::: ::::::.:.
NP_001 DHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGK
400 410 420 430 440 450
540 550 560 570 580 590
pF1KE0 CIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNE
::::: :::::.:..:.:..::.::.::...: : ::::.::.:::...:: :::.. .
NP_001 CIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDG
460 470 480 490 500 510
600 610 620 630 640 650
pF1KE0 EHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTA
:: :..::::.::: . ::.::.:.:. ::..:.::::. :: ..::: ::::...:
NP_001 EHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASA
520 530 540 550 560 570
660 670 680 690 700 710
pF1KE0 RHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIM
:.::...:.:... ::...:. .::....::: :...::.:: .::.... ..:...:
NP_001 RKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATIT
580 590 600 610 620 630
720 730 740 750
pF1KE0 PSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
:.:.::..: :::::: ..::.: :.:..: .::: :::..
NP_001 PDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK
640 650 660 670
>>NP_001274421 (OMIM: 615383) fidgetin-like protein 1 is (674 aa)
initn: 1481 init1: 1183 opt: 1303 Z-score: 516.2 bits: 106.1 E(85289): 5.1e-22
Smith-Waterman score: 1498; 38.0% identity (66.4% similar) in 744 aa overlap (19-759:12-674)
10 20 30 40 50
pF1KE0 MISSTSVYGLKMQWTPEHAQWPEQHFDITS-TTRSPAHKVEAYRGHLQRTYQYAWANDDI
..: ...: ::: .: :..:::... : ::::::..:
NP_001 MQTSSSRSVHLSEWQKNYFAITSGICTGP--KADAYRAQILRI-QYAWANSEI
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 SALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVY
: . :..:.::::::::.:... . :.::... :.......:. :: .:. . :.
NP_001 SQVCATKLFKKYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 PMNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAG
:. : .. :.: .: : :: .:. : . :. . :..: .:::
NP_001 KMSSVQKMMQAGKKFKDSLLEPALASVVIHKE---ATVFDLPKFS--VCGS---------
120 130 140 150
180 190 200 210 220 230
pF1KE0 LPSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGT
::: :.. :. .: :. . :. ::: :: .: .
NP_001 --SQESDSLPNSA--HDRDRTQDF-----PESNRLK---LLQNAQPP-----MVTN----
160 170 180 190
240 250 260 270 280 290
pF1KE0 SNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHG
.. . :. : : :: . . : : ... . : . .
NP_001 ---TARTCPTFSAP----VGESATAKFHVTP----LFGNVKKENHSSAKENIGLNVFLSN
200 210 220 230 240
300 310 320 330 340 350
pF1KE0 LTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNT
. . :.: : .::.:: :.: .:. ..:. :. .
NP_001 QSCF-PAACENP-----QRKSFY--GSGTIDA------------LSNPIL----NKACSK
250 260 270 280
360 370 380 390 400 410
pF1KE0 NRGNGFDRSAETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLG-SRSSE
.. :: : ::: .:: .:. . .::.:. : .:: . ::. .:.::: :::
NP_001 TEDNG---PKEDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYGGVKKSLGASRSRG
290 300 310 320 330
420 430 440 450 460 470
pF1KE0 SFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEII
.::.. :. .. : :. .. : : : : :::.::: . ..:.:. :::.
NP_001 ILGKFVPPIPKQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNLEPKMIELIMNEIM
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE0 TQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGR
.::::.:.::::....::.::: :.::.:: : :.:: . :..:::::: ::::::.:.
NP_001 DHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGK
400 410 420 430 440 450
540 550 560 570 580 590
pF1KE0 CIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNE
::::: :::::.:..:.:..::.::.::...: : ::::.::.:::...:: :::.. .
NP_001 CIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDG
460 470 480 490 500 510
600 610 620 630 640 650
pF1KE0 EHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTA
:: :..::::.::: . ::.::.:.:. ::..:.::::. :: ..::: ::::...:
NP_001 EHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASA
520 530 540 550 560 570
660 670 680 690 700 710
pF1KE0 RHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIM
:.::...:.:... ::...:. .::....::: :...::.:: .::.... ..:...:
NP_001 RKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATIT
580 590 600 610 620 630
720 730 740 750
pF1KE0 PSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
:.:.::..: :::::: ..::.: :.:..: .::: :::..
NP_001 PDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCGK
640 650 660 670
759 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:44:28 2016 done: Fri Nov 4 05:44:30 2016
Total Scan time: 13.920 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]