Result of FASTA (omim) for
pF1KE0014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0014, 487 aa
1>>>pF1KE0014 487 - 487 aa - 487 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.2470+/-0.000565; mu= 23.9646+/- 0.035
mean_var=66.9093+/-14.423, 0's: 0 Z-trim(106.0): 82 B-trim: 405 in 2/48
Lambda= 0.156795
statistics sampled from 14036 (14114) to 14036 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.499), E-opt: 0.2 (0.165), width: 16
Scan time: 7.510
The best scores are: opt bits E(85289)
NP_005759 (OMIM: 611950) lysophospholipid acyltran ( 487) 3270 749.6 4.5e-216
NP_001308195 (OMIM: 611949) lysophospholipid acylt ( 387) 249 66.1 2e-10
NP_001308196 (OMIM: 611949) lysophospholipid acylt ( 431) 249 66.2 2.1e-10
NP_001308194 (OMIM: 611949) lysophospholipid acylt ( 431) 249 66.2 2.1e-10
NP_620154 (OMIM: 611949) lysophospholipid acyltran ( 520) 249 66.3 2.4e-10
XP_006715062 (OMIM: 611732) PREDICTED: lysophospho ( 463) 244 65.1 4.9e-10
NP_001073949 (OMIM: 611732) lysophospholipid acylt ( 495) 244 65.1 5.1e-10
NP_001139554 (OMIM: 606048) lysophospholipid acylt ( 344) 219 59.3 2e-08
XP_016882785 (OMIM: 606048) PREDICTED: lysophospho ( 345) 219 59.3 2e-08
NP_982299 (OMIM: 300651,305600) protein-serine O-p ( 456) 201 55.4 4.1e-07
XP_005272692 (OMIM: 300651,305600) PREDICTED: prot ( 569) 201 55.5 4.8e-07
NP_982300 (OMIM: 300651,305600) protein-serine O-p ( 455) 197 54.4 7.7e-07
XP_006724610 (OMIM: 300651,305600) PREDICTED: prot ( 390) 190 52.8 2.1e-06
XP_006724609 (OMIM: 300651,305600) PREDICTED: prot ( 461) 190 52.9 2.3e-06
NP_982301 (OMIM: 300651,305600) protein-serine O-p ( 461) 190 52.9 2.3e-06
XP_006724608 (OMIM: 300651,305600) PREDICTED: prot ( 478) 190 52.9 2.4e-06
XP_005272694 (OMIM: 300651,305600) PREDICTED: prot ( 545) 190 53.0 2.6e-06
XP_016885224 (OMIM: 300651,305600) PREDICTED: prot ( 574) 190 53.0 2.7e-06
XP_011512615 (OMIM: 611732) PREDICTED: lysophospho ( 241) 186 51.7 2.8e-06
XP_006715063 (OMIM: 611732) PREDICTED: lysophospho ( 248) 186 51.7 2.9e-06
XP_016869215 (OMIM: 611940) PREDICTED: ghrelin O-a ( 435) 173 49.0 3.2e-05
NP_001094386 (OMIM: 611940) ghrelin O-acyltransfer ( 435) 173 49.0 3.2e-05
XP_011508616 (OMIM: 611949) PREDICTED: lysophospho ( 343) 148 43.2 0.0014
XP_011508615 (OMIM: 611949) PREDICTED: lysophospho ( 343) 148 43.2 0.0014
NP_001139555 (OMIM: 606048) lysophospholipid acylt ( 399) 137 40.8 0.0086
NP_001139528 (OMIM: 606048) lysophospholipid acylt ( 399) 137 40.8 0.0086
NP_077274 (OMIM: 606048) lysophospholipid acyltran ( 472) 137 40.9 0.0096
XP_011525601 (OMIM: 606048) PREDICTED: lysophospho ( 472) 137 40.9 0.0096
XP_011525602 (OMIM: 606048) PREDICTED: lysophospho ( 472) 137 40.9 0.0096
>>NP_005759 (OMIM: 611950) lysophospholipid acyltransfer (487 aa)
initn: 3270 init1: 3270 opt: 3270 Z-score: 4000.2 bits: 749.6 E(85289): 4.5e-216
Smith-Waterman score: 3270; 100.0% identity (100.0% similar) in 487 aa overlap (1-487:1-487)
10 20 30 40 50 60
pF1KE0 MASSAEGDEGTVVALAGVLQSGFQELSLNKLATSLGASEQALRLIISIFLGYPFALFYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MASSAEGDEGTVVALAGVLQSGFQELSLNKLATSLGASEQALRLIISIFLGYPFALFYRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 YLFYKETYLIHLFHTFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLMGRTITAVLTTFCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YLFYKETYLIHLFHTFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLMGRTITAVLTTFCF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QMAYLLAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDGGKDQNSLSSEQQKYAIRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QMAYLLAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDGGKDQNSLSSEQQKYAIRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 VPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIPGKIPNSIIPALKRLSLGLFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIPGKIPNSIIPALKRLSLGLFY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LVGYTLLSPHITEDYLLTEDYDNHPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILTGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LVGYTLLSPHITEDYLLTEDYDNHPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILTGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIFKRLKFLGNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIFKRLKFLGNKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQESPTLSKLAAITVLQPFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQESPTLSKLAAITVLQPFY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFLSLLFILPYIHKAMVPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFLSLLFILPYIHKAMVPRK
430 440 450 460 470 480
pF1KE0 EKLKKME
:::::::
NP_005 EKLKKME
>>NP_001308195 (OMIM: 611949) lysophospholipid acyltrans (387 aa)
initn: 291 init1: 177 opt: 249 Z-score: 308.2 bits: 66.1 E(85289): 2e-10
Smith-Waterman score: 401; 25.7% identity (55.3% similar) in 342 aa overlap (147-470:3-331)
120 130 140 150 160 170
pF1KE0 TFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDGG--KDQNSLSSEQQ
..: :. .:: . :: ::.. :.: :.
NP_001 MMIITQKITSLACEIHDGMFRKDEE-LTSSQR
10 20 30
180 190 200 210 220
pF1KE0 KYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIP-----GK-------
:.: .::::: ... . ..:.:: :.. :. ...:. : ::
NP_001 DLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYER
40 50 60 70 80 90
230 240 250 260 270
pF1KE0 ---IPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYLLTEDYDNHPFW-FRCMYMLIWGK
::. . . : : :: : :. . . .: . : .. : . .:. :
NP_001 TEPSPNTAV-VQKLLVCGLSLLFHLTICTT-LPVEYNIDEHFQATASWPTKIIYLYISLL
100 110 120 130 140
280 290 300 310 320 330
pF1KE0 FVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASFN
. :: : ..... .:.:: :..:.: :.:: .:... .: . : . ..:
NP_001 AARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWN
150 160 170 180 190 200
340 350 360 370 380 390
pF1KE0 INTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAA
:.: :. : ..: .: . . .... :.:::.. :: . :: .. ::
NP_001 IQTALWLKRVCYERTSFSPTIQ-----TFILSAIWHGVYPGYY----LTFLTGVLMTLAA
210 220 230 240 250 260
400 410 420 430 440 450
pF1KE0 RLIQESPTLSKLAAITVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLG
: .... . . :. :: .. . . ..:... : :.. : :.: :.
NP_001 RAMRNNFR-HYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCL
270 280 290 300 310
460 470 480
pF1KE0 HIFFLSLLFILPYIHKAMVPRKEKLKKME
::. . .:..::
NP_001 HILGILVLLLLPVKKTQRRKNTHENIQLSQSKKFDEGENSLGQNSFSTTNNVCNQNQEIA
320 330 340 350 360 370
>>NP_001308196 (OMIM: 611949) lysophospholipid acyltrans (431 aa)
initn: 291 init1: 177 opt: 249 Z-score: 307.6 bits: 66.2 E(85289): 2.1e-10
Smith-Waterman score: 432; 25.6% identity (54.9% similar) in 375 aa overlap (118-470:14-375)
90 100 110 120 130 140
pF1KE0 NQLYHSLLCIVLQFLILRLMGRTITAVLTTFCFQMAYL----LAGYYYTATGNYDIKWTM
: : ..:: .. : :.:. ..
NP_001 MIIIGVENMHNYCFVFALGYLTVCQVTRVYIFDYGQYSADFSG
10 20 30 40
150 160 170 180 190 200
pF1KE0 PHCVLTLKLIGLAVDYFDGG--KDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGP
: ..: :. .:: . :: ::.. :.: :. :.: .::::: ... . ..:.::
NP_001 PMMIITQKITSLACEIHDGMFRKDEE-LTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGP
50 60 70 80 90 100
210 220 230 240
pF1KE0 QFSMNHYMKLVQGELIDIP-----GK----------IPNSIIPALKRLSLGLFYLVGYTL
:.. :. ...:. : :: ::. . . : : :: : :.
NP_001 LCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAV-VQKLLVCGLSLLFHLTI
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE0 LSPHITEDYLLTEDYDNHPFW-FRCMYMLIWGKFVLYKYVTCWLVTEGVCILTGLGFNGF
. . .: . : .. : . .:. : . :: : ..... .:.:: :.
NP_001 CTT-LPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGY
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE0 EEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIFKRLKFLGNKELSQGL
.:.: :.:: .:... .: . : . ..::.: :. : ..: .: . .
NP_001 DENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFSPTIQ-----
230 240 250 260 270
370 380 390 400 410 420
pF1KE0 SLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQESPTLSKLAAITVLQPFYYLVQQ
.... :.:::.. :: . : :... ::: .... . . :. :: ..
NP_001 TFILSAIWHGVYPGYYLTFLTGVLMTL----AARAMRNN-FRHYFIEPSQLKLFYDVITW
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE0 TIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFLSLLFILPYIHKAMVPRKEKLKK
. . ..:... : :.. : :.: :. ::. . .:..::
NP_001 IVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVKKTQRRKNTHENIQ
340 350 360 370 380 390
pF1KE0 ME
NP_001 LSQSKKFDEGENSLGQNSFSTTNNVCNQNQEIASRHSSLKQ
400 410 420 430
>>NP_001308194 (OMIM: 611949) lysophospholipid acyltrans (431 aa)
initn: 291 init1: 177 opt: 249 Z-score: 307.6 bits: 66.2 E(85289): 2.1e-10
Smith-Waterman score: 432; 25.6% identity (54.9% similar) in 375 aa overlap (118-470:14-375)
90 100 110 120 130 140
pF1KE0 NQLYHSLLCIVLQFLILRLMGRTITAVLTTFCFQMAYL----LAGYYYTATGNYDIKWTM
: : ..:: .. : :.:. ..
NP_001 MIIIGVENMHNYCFVFALGYLTVCQVTRVYIFDYGQYSADFSG
10 20 30 40
150 160 170 180 190 200
pF1KE0 PHCVLTLKLIGLAVDYFDGG--KDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGP
: ..: :. .:: . :: ::.. :.: :. :.: .::::: ... . ..:.::
NP_001 PMMIITQKITSLACEIHDGMFRKDEE-LTSSQRDLAVRRMPSLLEYLSYNCNFMGILAGP
50 60 70 80 90 100
210 220 230 240
pF1KE0 QFSMNHYMKLVQGELIDIP-----GK----------IPNSIIPALKRLSLGLFYLVGYTL
:.. :. ...:. : :: ::. . . : : :: : :.
NP_001 LCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAV-VQKLLVCGLSLLFHLTI
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE0 LSPHITEDYLLTEDYDNHPFW-FRCMYMLIWGKFVLYKYVTCWLVTEGVCILTGLGFNGF
. . .: . : .. : . .:. : . :: : ..... .:.:: :.
NP_001 CTT-LPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGFRGY
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE0 EEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIFKRLKFLGNKELSQGL
.:.: :.:: .:... .: . : . ..::.: :. : ..: .: . .
NP_001 DENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFSPTIQ-----
230 240 250 260 270
370 380 390 400 410 420
pF1KE0 SLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQESPTLSKLAAITVLQPFYYLVQQ
.... :.:::.. :: . : :... ::: .... . . :. :: ..
NP_001 TFILSAIWHGVYPGYYLTFLTGVLMTL----AARAMRNN-FRHYFIEPSQLKLFYDVITW
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE0 TIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFLSLLFILPYIHKAMVPRKEKLKK
. . ..:... : :.. : :.: :. ::. . .:..::
NP_001 IVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVKKTQRRKNTHENIQ
340 350 360 370 380 390
pF1KE0 ME
NP_001 LSQSKKFDEGENSLGQNSFSTTNNVCNQNQEIASRHSSLKQ
400 410 420 430
>>NP_620154 (OMIM: 611949) lysophospholipid acyltransfer (520 aa)
initn: 320 init1: 177 opt: 249 Z-score: 306.7 bits: 66.3 E(85289): 2.4e-10
Smith-Waterman score: 498; 24.7% identity (55.0% similar) in 469 aa overlap (28-470:12-464)
10 20 30 40 50 60
pF1KE0 MASSAEGDEGTVVALAGVLQSGFQELSLNKLATSLGASEQALRLIISIFLGYPFALFYRH
:. :.... . . ... ... :...:
NP_620 MATTSTTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRT
10 20 30 40
70 80 90 100 110
pF1KE0 YLFYKET--YLIHLFHTFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLMGRTITAVLTTF
:: ..: .. :. :. :: .: : :: : :. ... :. ..: . . ..
NP_620 YLHSSKTSSFIRHVVATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIG---VENMHNY
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 CFQMA--YL----LAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDGG--KDQNSLS
:: .: :: .. : :.:. .. : ..: :. .:: . :: ::.. :.
NP_620 CFVFALGYLTVCQVTRVYIFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEE-LT
110 120 130 140 150 160
180 190 200 210 220
pF1KE0 SEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIP-----GK---
: :. :.: .::::: ... . ..:.:: :.. :. ...:. : ::
NP_620 SSQRDLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEET
170 180 190 200 210 220
230 240 250 260 270
pF1KE0 -------IPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYLLTEDYDNHPFW-FRCMYML
::. . . : : :: : :. . . .: . : .. : . .:.
NP_620 QYERTEPSPNTAV-VQKLLVCGLSLLFHLTICTT-LPVEYNIDEHFQATASWPTKIIYLY
230 240 250 260 270
280 290 300 310 320 330
pF1KE0 IWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTI
: . :: : ..... .:.:: :..:.: :.:: .:... .: . : .
NP_620 ISLLAARPKYYFAWTLADAINNAAGFGFRGYDENGAARWDLISNLRIQQIEMSTSFKMFL
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE0 ASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVE
..::.: :. : ..: .: . . .... :.:::.. :: . :: ..
NP_620 DNWNIQTALWLKRVCYERTSFSPTIQ-----TFILSAIWHGVYPGYY----LTFLTGVLM
340 350 360 370 380
400 410 420 430 440 450
pF1KE0 RQAARLIQESPTLSKLAAITVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSI
::: .... . . :. :: .. . . ..:... : :.. : :.:
NP_620 TLAARAMRNN-FRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSW
390 400 410 420 430 440
460 470 480
pF1KE0 YFLGHIFFLSLLFILPYIHKAMVPRKEKLKKME
:. ::. . .:..::
NP_620 YYCLHILGILVLLLLPVKKTQRRKNTHENIQLSQSKKFDEGENSLGQNSFSTTNNVCNQN
450 460 470 480 490 500
>>XP_006715062 (OMIM: 611732) PREDICTED: lysophospholipi (463 aa)
initn: 329 init1: 154 opt: 244 Z-score: 301.2 bits: 65.1 E(85289): 4.9e-10
Smith-Waterman score: 453; 23.1% identity (54.9% similar) in 459 aa overlap (45-482:9-452)
20 30 40 50 60 70
pF1KE0 LAGVLQSGFQELSLNKLATSLGASEQALRLIISIFLGYPFALFYRHYLFYKETYLIHLFH
....: .. : .. : ... :
XP_006 MVNFVVCQLVALFAAFWFRIYLRPGTTSSDVR--HAVA
10 20 30
80 90 100 110 120
pF1KE0 TFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLMGRTITAVLT-TFCFQMAYL----LAGY
:. :. .. : :: : .. ... . :. . ... . .: :.:: ..
XP_006 TIFGIYFVIFCFGWYSVHLFVLVLMCYAIM--VTASVSNIHRYSFFVAMGYLTICHISRI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 YYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDG-GKDQNSLSSEQQKYAIRGVPSLLEVA
: : .. : ..: :. :: . :: :. ..::.::.. ::. ::.::
XP_006 YIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYL
100 110 120 130 140 150
190 200 210 220 230
pF1KE0 GFSYFYGAFLVGPQFSMNHYMKLVQGE-----LIDIPGKI--------PNSIIPALKRLS
.. . . ..:: ... :. ...:. :... : :. ....:.
XP_006 SYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGAVIHKLG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE0 LGLFYLVGYTLLSPHITEDYLLTEDYDNHPFWF--RCMYMLIWGKFVLYKYVTCWLVTEG
. : :. . :. . :..:. : : : :. . . :: : ....
XP_006 ITLVSLLLFLTLTKTFPVT-CLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADA
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE0 VCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIFKRL
: .:.::.: ...:. :: .:...: .:: : . ..::.: .:. ..:.
XP_006 VNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQRV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE0 KFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQESPTLSKLAAI
. . :.... :::::.. :: : .:.... : :.: . ::. :
XP_006 PWYPTV-----LTFILSALWHGVYPGYYFTFLTGILVTLAAR-AVRNNYRHYFLSSRA--
340 350 360 370 380
420 430 440 450 460 470
pF1KE0 TVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFLSLLFILPYIH
:. : .. : ..:... : ... . ...:::.:: ::. : ....::.
XP_006 --LKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKP
390 400 410 420 430 440
480
pF1KE0 KAMVPRKEKLKKME
.: . :. .
XP_006 QAHTQRRPQTLNSINKRKTD
450 460
>>NP_001073949 (OMIM: 611732) lysophospholipid acyltrans (495 aa)
initn: 329 init1: 154 opt: 244 Z-score: 300.8 bits: 65.1 E(85289): 5.1e-10
Smith-Waterman score: 460; 23.6% identity (54.8% similar) in 478 aa overlap (28-482:20-484)
10 20 30 40 50 60
pF1KE0 MASSAEGDEGTVVALAGVLQSGFQELSLNKLATSLGASEQALRLIISIFLGYPFALFYRH
:. :. :: . . ... ... :...:
NP_001 MAAEPQPSSLSYRTTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRI
10 20 30 40 50
70 80 90 100 110
pF1KE0 YLFYKETY--LIHLFHTFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLMGRTITAVLT-T
:: : . : :. :. .. : :: : .. ... . :. . ... . .
NP_001 YLRPGTTSSDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIM--VTASVSNIHRYS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 FCFQMAYL----LAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDG-GKDQNSLSSE
: :.:: .. : : .. : ..: :. :: . :: :. ..::.:
NP_001 FFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAE
120 130 140 150 160 170
180 190 200 210 220
pF1KE0 QQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGE-----LIDIPGKI----
:.. ::. ::.:: .. . . ..:: ... :. ...:. :... :
NP_001 QHRLAIKVKPSFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFH
180 190 200 210 220 230
230 240 250 260 270
pF1KE0 ----PNSIIPALKRLSLGLFYLVGYTLLSPHITEDYLLTEDYDNHPFWF--RCMYMLIWG
:. ....:.. : :. . :. . :. .:. : : : :. .
NP_001 SLPEPSPTGAVIHKLGITLVSLLLFLTLTKTFPVTCLV-DDWFVHKASFPARLCYLYVVM
240 250 260 270 280
280 290 300 310 320 330
pF1KE0 KFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASF
. :: : ....: .:.::.: ...:. :: .:...: .:: : . ..
NP_001 QASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENW
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE0 NINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQA
::.: .:. ..:. . . :.... :::::.. :: : .:.... : :
NP_001 NIQTATWLKCVCYQRVPWYPTV-----LTFILSALWHGVYPGYYFTFLTGILVTLAAR-A
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE0 ARLIQESPTLSKLAAITVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFL
.: . ::. : .: . . : : : ..:... : ... . ...:::.::
NP_001 VRNNYRHYFLSSRALKAVYDAGTWAVTQ----LAVSYTVAPFVMLAVEPTISLYKSMYFY
410 420 430 440 450
460 470 480
pF1KE0 GHIFFLSLLFILPYIHKAMVPRKEKLKKME
::. : ....::. .: . :. .
NP_001 LHIISLLIILFLPMKPQAHTQRRPQTLNSINKRKTD
460 470 480 490
>>NP_001139554 (OMIM: 606048) lysophospholipid acyltrans (344 aa)
initn: 131 init1: 83 opt: 219 Z-score: 272.1 bits: 59.3 E(85289): 2e-08
Smith-Waterman score: 226; 28.3% identity (54.7% similar) in 247 aa overlap (78-311:38-272)
50 60 70 80 90 100
pF1KE0 IFLGYPFALFYRHYLFYKETYLIHLFHTFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLM
::... :. : . :::. :. . ... .
NP_001 YLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQ
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE0 GRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMP-----HCVLTLKLIGLAVDYFDG
. :. .. : .::: .. : . . : . .:::::..:: . :
NP_001 PCSCHALALAWTF--SYLL---FFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDL
70 80 90 100 110 120
170 180 190 200 210
pF1KE0 GKDQNS-LSSEQQKYAIRG----VPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELI
: . ..: .: : ::::.:. ..:: : ....:: : . :. .. .
NP_001 HLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPF-
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE0 DIPGKIPNSIIPALKRL-SLGLFYLVGYTLLSPHITEDYLLTED-YDNHPFWFRCMYML-
:: .: :. : :.: :: :. ::: :. . :: . .:. : .::.
NP_001 --PGAVP-SLRPLLRRAWPAPLFGLL--FLLSSHLFPLEAVREDAFYARPLPARLFYMIP
190 200 210 220 230
280 290 300 310 320 330
pF1KE0 IWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTI
.. : . ::. :...: :: .:.: :..:
NP_001 VFFAFRMRFYVA-WIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYD
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE0 ASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVE
NP_001 YETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR
300 310 320 330 340
>>XP_016882785 (OMIM: 606048) PREDICTED: lysophospholipi (345 aa)
initn: 131 init1: 83 opt: 219 Z-score: 272.1 bits: 59.3 E(85289): 2e-08
Smith-Waterman score: 226; 28.3% identity (54.7% similar) in 247 aa overlap (78-311:38-272)
50 60 70 80 90 100
pF1KE0 IFLGYPFALFYRHYLFYKETYLIHLFHTFTGLSIAYFNFGNQLYHSLLCIVLQFLILRLM
::... :. : . :::. :. . ... .
XP_016 YLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQ
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE0 GRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMP-----HCVLTLKLIGLAVDYFDG
. :. .. : .::: .. : . . : . .:::::..:: . :
XP_016 PCSCHALALAWTF--SYLL---FFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDL
70 80 90 100 110 120
170 180 190 200 210
pF1KE0 GKDQNS-LSSEQQKYAIRG----VPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELI
: . ..: .: : ::::.:. ..:: : ....:: : . :. .. .
XP_016 HLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPF-
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE0 DIPGKIPNSIIPALKRL-SLGLFYLVGYTLLSPHITEDYLLTED-YDNHPFWFRCMYML-
:: .: :. : :.: :: :. ::: :. . :: . .:. : .::.
XP_016 --PGAVP-SLRPLLRRAWPAPLFGLL--FLLSSHLFPLEAVREDAFYARPLPARLFYMIP
190 200 210 220 230
280 290 300 310 320 330
pF1KE0 IWGKFVLYKYVTCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTI
.. : . ::. :...: :: .:.: :..:
XP_016 VFFAFRMRFYVA-WIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYD
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE0 ASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVE
XP_016 YETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRL
300 310 320 330 340
>>NP_982299 (OMIM: 300651,305600) protein-serine O-palmi (456 aa)
initn: 162 init1: 111 opt: 201 Z-score: 248.7 bits: 55.4 E(85289): 4.1e-07
Smith-Waterman score: 223; 26.3% identity (52.7% similar) in 410 aa overlap (20-409:7-374)
10 20 30 40 50 60
pF1KE0 MASSAEGDEGTVVALAGVLQSGFQELSLNKLATSLGASEQALRLIISIFLGYPFALFYRH
: ::.: . : . . . . :...: :. :..:
NP_982 MATFSRQEFFQQLLQGCLLPTAQQGLDQIWLLLAICLA--CRLLWRL
10 20 30 40
70 80 90 100 110
pF1KE0 YLFYKETYLIHLFHTFTGLSIAYFNFGNQLYH------SLLCIVLQFLILRLMGRTITAV
: .:: : : .: .. ..: ::. :::: .. :: . : .
NP_982 GL---PSYLKHA-STVAGGFFSLYHFF-QLHMVWVVLLSLLCYLVLFLCRHSSHRGVFLS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 LTTFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKLIGLAVDYFDGGKDQNSLSSEQQ
.: . ::: : .. . : . ....: ..:. : .: :.
NP_982 VTI----LIYLLMGEMHMVDTVTWHKMRGAQMIVAMKAVSLGFD-LDRGE----------
110 120 130 140
180 190 200 210 220 230
pF1KE0 KYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIP--GKIPNSIIPALK
. ::: .: :. :: :... :: .:.. :.. :::. .. :. :. ::
NP_982 ---VGTVPSPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRPLSCRWLQKVARSL--ALA
150 160 170 180 190 200
240 250 260 270 280
pF1KE0 RLSLGLFYLVGYTLLSPH---ITEDYLLTEDYDNHPFWFRCMYMLIWGKFVLYKYVTCWL
: : : :: :. :. .. : :: .. . :.: . . .: . .: . .:
NP_982 LLCLVLSTCVGPYLF-PYFIPLNGDRLL-RNKKRKARWLRAYESAV--SFHFSNYFVGFL
210 220 230 240 250
290 300 310 320 330 340
pF1KE0 VTEGVCILTGLGFNGFEEKGKAKWDACAN--MKVWLFETNPR-FTGTIASFNINTNAWVA
.:.. :.: ::. ::: . .:: .. ..: : :: .. ...:.:. . :.
NP_982 -SEATATLAGAGFT--EEKDHLEWDLTVSKPLNVEL----PRSMVEVVTSWNLPMSYWLN
260 270 280 290 300
350 360 370 380 390 400
pF1KE0 RYIFKRLKFLGNKELSQGL-SLLFLALWHGLHSGYL--VCFQMEFLIVI---VERQAARL
:.:: ::. .: : . :: ::. : .: : ... :. . .... ::.
NP_982 NYVFKNALRLGT--FSAVLVTYAASALLHGF-SFHLAAVLLSLAFITYVEHVLRKRLARI
310 320 330 340 350 360
410 420 430 440 450 460
pF1KE0 IQESPTLSKLAAITVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHI
.. .:::
NP_982 LSAC-VLSKRCPPDCSHQHRLGLGVRALNLLFGALAIFHLAYLGSLFDVDVDDTTEEQGY
370 380 390 400 410 420
487 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:23:10 2016 done: Fri Nov 4 08:23:11 2016
Total Scan time: 7.510 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]