Result of FASTA (omim) for
pF1KB9989
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9989, 579 aa
1>>>pF1KB9989 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6821+/-0.000417; mu= 13.7210+/- 0.026
mean_var=173.0127+/-37.303, 0's: 0 Z-trim(115.7): 286 B-trim: 1223 in 1/53
Lambda= 0.097507
statistics sampled from 25958 (26311) to 25958 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.308), width: 16
Scan time: 9.390
The best scores are: opt bits E(85289)
NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579) 3961 570.2 6.5e-162
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 463 77.8 6.1e-14
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 463 77.8 6.1e-14
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 463 77.8 6.1e-14
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 411 70.5 1e-11
NP_060444 (OMIM: 610767,611081) autophagy-related ( 588) 316 57.4 1.5e-07
NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 310 56.5 2.4e-07
NP_942593 (OMIM: 610767,611081) autophagy-related ( 444) 305 55.7 3.6e-07
XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463) 305 55.8 3.7e-07
XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480) 305 55.8 3.8e-07
NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491) 305 55.8 3.9e-07
NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523) 305 55.8 4e-07
XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540) 305 55.8 4.1e-07
NP_110430 (OMIM: 610767,611081) autophagy-related ( 607) 305 55.9 4.4e-07
XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624) 305 55.9 4.5e-07
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 298 54.8 7.5e-07
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 300 55.2 7.6e-07
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 300 55.2 7.6e-07
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 300 55.2 7.6e-07
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 300 55.2 7.6e-07
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 300 55.3 7.7e-07
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 300 55.3 7.7e-07
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 300 55.3 7.7e-07
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 300 55.3 7.8e-07
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 300 55.3 7.8e-07
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 300 55.3 7.8e-07
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 300 55.3 7.8e-07
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 294 54.1 9.7e-07
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 291 53.6 1.2e-06
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 291 53.6 1.2e-06
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 291 53.6 1.2e-06
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 291 53.6 1.2e-06
XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 294 54.3 1.2e-06
XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 294 54.3 1.2e-06
XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 294 54.3 1.2e-06
XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 294 54.3 1.2e-06
XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537) 294 54.3 1.2e-06
XP_011510121 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 294 54.3 1.3e-06
XP_011510116 (OMIM: 612173) PREDICTED: sperm-assoc ( 600) 294 54.4 1.3e-06
NP_078808 (OMIM: 612173) sperm-associated antigen ( 631) 294 54.4 1.3e-06
XP_016877356 (OMIM: 604447) PREDICTED: guanine nuc ( 212) 286 52.7 1.4e-06
XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 286 52.9 1.8e-06
XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 286 53.0 2e-06
NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 286 53.0 2e-06
NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 286 53.0 2.1e-06
XP_011510120 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 286 53.2 2.7e-06
XP_011510119 (OMIM: 612173) PREDICTED: sperm-assoc ( 582) 286 53.2 2.8e-06
XP_011510117 (OMIM: 612173) PREDICTED: sperm-assoc ( 592) 286 53.2 2.8e-06
XP_011510118 (OMIM: 612173) PREDICTED: sperm-assoc ( 592) 286 53.2 2.8e-06
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 280 52.0 3.2e-06
>>NP_056975 (OMIM: 605585) pre-mRNA-processing factor 17 (579 aa)
initn: 3961 init1: 3961 opt: 3961 Z-score: 3027.8 bits: 570.2 E(85289): 6.5e-162
Smith-Waterman score: 3961; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KB9 MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 GHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 TETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 MDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTT
490 500 510 520 530 540
550 560 570
pF1KB9 KLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD
:::::::::::::::::::::::::::::::::::::::
NP_056 KLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD
550 560 570
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 552 init1: 164 opt: 463 Z-score: 371.2 bits: 77.8 E(85289): 6.1e-14
Smith-Waterman score: 463; 27.8% identity (62.2% similar) in 299 aa overlap (285-578:42-330)
260 270 280 290 300 310
pF1KB9 LHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIK
.::::.::.:.. : .:. : : : : ::
NP_438 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIK
20 30 40 50 60 70
320 330 340 350 360 370
pF1KB9 LWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRK
.: .: . . .:. ::. .. :. ... .. ..::. :. ::.::. .:.:.. . ...
NP_438 IWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHS
80 90 100 110 120
380 390 400 410 420 430
pF1KB9 -VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRF
.: .::: ..::.:.: :... ::...:. .. : :... : .. .
NP_438 NYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI
130 140 150 160 170 180
440 450 460 470 480 490
pF1KB9 VSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNR
::.: : :.:. .: . . . . : .:::::.. ..:: . .. .
NP_438 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW---DY
190 200 210 220 230 240
500 510 520 530 540 550
pF1KB9 FRLNKKKIFKGHMVAGYACQVDFS-PDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKV
. . : . :: : ..:: ....::. .. . ::. .: .. .....: :
NP_438 SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV
250 260 270 280 290 300
560 570
pF1KB9 CIGAVWHPHETSKVITCGW---DGLIKLWD
:... :: :. .:. . : ::::
NP_438 VISTACHPTEN--IIASAALENDKTIKLWKSDC
310 320 330
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 552 init1: 164 opt: 463 Z-score: 371.2 bits: 77.8 E(85289): 6.1e-14
Smith-Waterman score: 463; 27.8% identity (62.2% similar) in 299 aa overlap (285-578:42-330)
260 270 280 290 300 310
pF1KB9 LHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIK
.::::.::.:.. : .:. : : : : ::
NP_060 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIK
20 30 40 50 60 70
320 330 340 350 360 370
pF1KB9 LWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRK
.: .: . . .:. ::. .. :. ... .. ..::. :. ::.::. .:.:.. . ...
NP_060 IWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHS
80 90 100 110 120
380 390 400 410 420 430
pF1KB9 -VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRF
.: .::: ..::.:.: :... ::...:. .. : :... : .. .
NP_060 NYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI
130 140 150 160 170 180
440 450 460 470 480 490
pF1KB9 VSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNR
::.: : :.:. .: . . . . : .:::::.. ..:: . .. .
NP_060 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW---DY
190 200 210 220 230 240
500 510 520 530 540 550
pF1KB9 FRLNKKKIFKGHMVAGYACQVDFS-PDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKV
. . : . :: : ..:: ....::. .. . ::. .: .. .....: :
NP_060 SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV
250 260 270 280 290 300
560 570
pF1KB9 CIGAVWHPHETSKVITCGW---DGLIKLWD
:... :: :. .:. . : ::::
NP_060 VISTACHPTEN--IIASAALENDKTIKLWKSDC
310 320 330
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 552 init1: 164 opt: 463 Z-score: 371.2 bits: 77.8 E(85289): 6.1e-14
Smith-Waterman score: 463; 27.8% identity (62.2% similar) in 299 aa overlap (285-578:42-330)
260 270 280 290 300 310
pF1KB9 LHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIK
.::::.::.:.. : .:. : : : : ::
XP_005 AARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSP-NGEWLASSSADKLIK
20 30 40 50 60 70
320 330 340 350 360 370
pF1KB9 LWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRK
.: .: . . .:. ::. .. :. ... .. ..::. :. ::.::. .:.:.. . ...
XP_005 IWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHS
80 90 100 110 120
380 390 400 410 420 430
pF1KB9 -VPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRF
.: .::: ..::.:.: :... ::...:. .. : :... : .. .
XP_005 NYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI
130 140 150 160 170 180
440 450 460 470 480 490
pF1KB9 VSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNR
::.: : :.:. .: . . . . : .:::::.. ..:: . .. .
XP_005 VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW---DY
190 200 210 220 230 240
500 510 520 530 540 550
pF1KB9 FRLNKKKIFKGHMVAGYACQVDFS-PDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKV
. . : . :: : ..:: ....::. .. . ::. .: .. .....: :
XP_005 SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV
250 260 270 280 290 300
560 570
pF1KB9 CIGAVWHPHETSKVITCGW---DGLIKLWD
:... :: :. .:. . : ::::
XP_005 VISTACHPTEN--IIASAALENDKTIKLWKSDC
310 320 330
>>NP_004805 (OMIM: 607797) U5 small nuclear ribonucleopr (357 aa)
initn: 272 init1: 166 opt: 411 Z-score: 331.3 bits: 70.5 E(85289): 1e-11
Smith-Waterman score: 411; 26.4% identity (58.1% similar) in 296 aa overlap (271-562:49-339)
250 260 270 280 290 300
pF1KB9 LHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLS
: .: . : . ::: : .. : .
NP_004 RQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHP-N
20 30 40 50 60 70
310 320 330 340 350 360
pF1KB9 GHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWD
: : : ..: : ::.:::. :. ::: :: .. .:: :....::. :. . .::
NP_004 GSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWD
80 90 100 110 120 130
370 380 390 400 410 420
pF1KB9 TETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGA
.:::. ..:. .. . . . : . .: .: .: . ::::. .: . ..
NP_004 SETGERVKRLKGH-TSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTF-QNTYQ
140 150 160 170 180 190
430 440 450 460 470 480
pF1KB9 VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQS
: ...: : . ...: . :....::. . : . :. ...:: .:..: ..
NP_004 VLAVTFNDTSDQIISGGIDNDIKVWDLR-QNKLTYTMRGHADSVTGLSLSSEGSYLLSNA
200 210 220 230 240 250
490 500 510 520 530
pF1KB9 MDNQILIFGAQNRFRLNKK--KIFKG--HMVAGYACQVDFSPDMSYVISGDGNGKLNIWD
::: . .. .. : ... :::.: : . ..::: : . .:... . .::
NP_004 MDNTVRVWDVRP-FAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWD
260 270 280 290 300 310
540 550 560 570
pF1KB9 WKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD
. .. .. .: ...:: :
NP_004 TTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ
320 330 340 350
>>NP_060444 (OMIM: 610767,611081) autophagy-related prot (588 aa)
initn: 283 init1: 106 opt: 316 Z-score: 256.6 bits: 57.4 E(85289): 1.5e-07
Smith-Waterman score: 342; 26.9% identity (54.7% similar) in 402 aa overlap (201-578:209-585)
180 190 200 210 220 230
pF1KB9 GQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQE
.::: . . . :::: : .::. .:.
NP_060 KLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAE-AAKEPLPVEQD
180 190 200 210 220 230
240 250 260 270
pF1KB9 EE----------KPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPP--EKCYLPK
.. . : . . ... .. : . .::: :. .: : .. .:
NP_060 DDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQD---NV-DTHPGSGKEVRVPA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB9 KQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIGHSKAVRD
. :...: :.::.. : : .:: . .:: ..:::::.::. .. .. : . .. .
NP_060 TALCVFDAHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITS
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB9 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQNLFVAGM
: :..::. .:.:. : ..: .. . .:.. :: .:: :. . .:.:
NP_060 IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR---IVSGS
360 370 380 390 400
400 410 420 430 440 450
pF1KB9 SDKKIVQWDIRSGEIVQEYDRHLGA-VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFK
:. . ::.:: .. :. : :: ... .: ::..: : :: .
NP_060 HDRTLKLWDLRSKVCIKTV--FAGSSCNDIVCTEQC--VMSGHFDKKIRFW--DIRSESI
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB9 YIAEPSMHSMPAVTLSPN-GKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMVAGYAC
. .. :. :.:. . :.: : :. . .. .: : :. :.. :. :
NP_060 VREMELLGKITALDLNPERTELLSC-SRDDLLKVID----LRTNAIKQTFSA---PGFKC
470 480 490 500 510
520 530 540 550 560
pF1KB9 QVD-----FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPHETSKV
: :::: ::: .:...:.: ::. : :. . .. . . :.:: : : :.:
NP_060 GSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS-GSHV
520 530 540 550 560 570
570
pF1KB9 ITCGWDGLIKLWD
.. ::
NP_060 VSVDKGCKAVLWAQY
580
>>NP_055317 (OMIM: 608330) pre-mRNA-processing factor 19 (504 aa)
initn: 234 init1: 209 opt: 310 Z-score: 252.8 bits: 56.5 E(85289): 2.4e-07
Smith-Waterman score: 324; 25.2% identity (56.6% similar) in 290 aa overlap (213-487:177-461)
190 200 210 220 230
pF1KB9 ENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGK---QEEEKPGEEKT
: . .:..:.:.:: .: :: : .
NP_055 PSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSK
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB9 ILHVKEMYDYQGRSYLHI------PQDVGVNLRSTMPPEKCYLPKKQIHVWS---GHTKG
.: .. : : :.:.. : . . . :.. .. . ::::
NP_055 YRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKK
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB9 VSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSA
:..: . : : :..: : : :..: : . :... .: .:: . ....: .::.
NP_055 VTSVVFHP-SQDLVFSASPDATIRIWSVPNAS-CVQVVRAHESAVTGLSLHATGDYLLSS
270 280 290 300 310 320
360 370 380 390 400
pF1KB9 AYDRYLKLWDTETGQCISRFTNRKVP---YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRS
. :.: . : .::. ... :.. :..:.:: .: .: :..: ::..
NP_055 SDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD---GLIFGTGTMDSQIKIWDLKE
330 340 350 360 370 380
410 420 430 440 450 460
pF1KB9 GEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAV
: .. : : ...:.: ... .....::.:...:. .:: . . . ..
NP_055 RTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSL
390 400 410 420 430 440
470 480 490 500 510 520
pF1KB9 TLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGD
.. .: .:: . : :: :
NP_055 IFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKF
450 460 470 480 490 500
>>NP_942593 (OMIM: 610767,611081) autophagy-related prot (444 aa)
initn: 257 init1: 106 opt: 305 Z-score: 249.6 bits: 55.7 E(85289): 3.6e-07
Smith-Waterman score: 334; 26.6% identity (55.2% similar) in 395 aa overlap (202-578:77-441)
180 190 200 210 220
pF1KB9 QKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEE----EQKELDEITAKRQKKG
.:..:. ..: :: . :. . . .
NP_942 DLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPVEQDDDIEVIVD-ETSD
50 60 70 80 90 100
230 240 250 260 270 280
pF1KB9 KQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPP--EKCYLPKKQIHVWS
. :: .: . ... .. : . .::: :. .: : .. .: . :..
NP_942 HTEETSP-----VRAISRAATRRSVSSFPVPQD---NV-DTHPGSGKEVRVPATALCVFD
110 120 130 140 150
290 300 310 320 330 340
pF1KB9 GHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIGHSKAVRDICFNTAG
.: :.::.. : : .:: . .:: ..:::::.::. .. .. : . .. .: :..::
NP_942 AHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAG
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB9 TQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQNLFVAGMSDKKIVQ
. .:.:. : ..: .. . .:.. :: .:: :. . .:.: :. .
NP_942 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR---IVSGSHDRTLKL
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB9 WDIRSGEIVQEYDRHLGA-VNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSM
::.:: .. :. : :: ... .: ::..: : :: . .
NP_942 WDLRSKVCIKTV--FAGSSCNDIVCTEQC--VMSGHFDKKIRFW--DIRSESIVREMELL
280 290 300 310 320
470 480 490 500 510
pF1KB9 HSMPAVTLSPN-GKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMVAGYACQVD----
.. :. :.:. . :.: : :. . .. .: : :. :.. :. : :
NP_942 GKITALDLNPERTELLSC-SRDDLLKVID----LRTNAIKQTFSA---PGFKCGSDWTRV
330 340 350 360 370
520 530 540 550 560 570
pF1KB9 -FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPHETSKVITCGWDG
:::: ::: .:...:.: ::. : :. . .. . . :.:: : : :.:..
NP_942 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS-GSHVVSVDKGC
380 390 400 410 420 430
pF1KB9 LIKLWD
::
NP_942 KAVLWAQY
440
>>XP_005246143 (OMIM: 610767,611081) PREDICTED: autophag (463 aa)
initn: 257 init1: 106 opt: 305 Z-score: 249.4 bits: 55.8 E(85289): 3.7e-07
Smith-Waterman score: 351; 24.8% identity (53.3% similar) in 467 aa overlap (128-578:28-460)
100 110 120 130 140 150
pF1KB9 PFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFAT----YGYALDPSLDNHQVSAKYI
::..: :. :. : : :.: :. .
XP_005 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKS-DLHSVLAQKL
10 20 30 40 50
160 170 180 190 200 210
pF1KB9 GSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQ
.:::.. . : ..... .:.. : . : . : . .. . ..
XP_005 ----QAEKHDVPNRHEIRRRQARLQKELAEAAKEPL-----PVEQDDDIEVIVDETSDHT
60 70 80 90 100
220 230 240 250 260 270
pF1KB9 KELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPP--
.: . . : . :. . : . . ... .. : . .::: :. .: :
XP_005 EETSPVRAISRAATKRLSQPAG--GLLDSITNIFGRRSVSSFPVPQD---NV-DTHPGSG
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB9 EKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIG
.. .: . :...: :.::.. : : .:: . .:: ..:::::.::. .. .. :
XP_005 KEVRVPATALCVFDAHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSG
170 180 190 200 210 220
340 350 360 370 380
pF1KB9 HSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQ
. .. .: :..::. .:.:. : ..: .. . .:.. :: .:: :. .
XP_005 SNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR-
230 240 250 260 270
390 400 410 420 430 440
pF1KB9 NLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWD
.:.: :. . ::.:: .. .. : :: ... .: ::..: ::
XP_005 --IVSGSHDRTLKLWDLRSKVCIKTV-FAGSSCNDIVCTEQC--VMSGHFDKKIRF--WD
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB9 IPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMV
: . . .. :. :.:. : : :. . .. .: : :. :..
XP_005 IRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVID----LRTNAIKQTFSA---
340 350 360 370 380
510 520 530 540 550 560
pF1KB9 AGYACQVD-----FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPH
:. : : :::: ::: .:...:.: ::. : :. . .. . . :.:: : :
XP_005 PGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS
390 400 410 420 430 440
570
pF1KB9 ETSKVITCGWDGLIKLWD
:.:.. ::
XP_005 -GSHVVSVDKGCKAVLWAQY
450 460
>>XP_005246141 (OMIM: 610767,611081) PREDICTED: autophag (480 aa)
initn: 257 init1: 106 opt: 305 Z-score: 249.3 bits: 55.8 E(85289): 3.8e-07
Smith-Waterman score: 330; 27.7% identity (55.1% similar) in 336 aa overlap (253-578:162-477)
230 240 250 260 270 280
pF1KB9 RQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIH
: . .::: .:. . : .: .
XP_005 LDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQD-NVDTHPGSGKE-VRVPATALC
140 150 160 170 180
290 300 310 320 330 340
pF1KB9 VWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLR-TFIGHSKAVRDICFN
:...: :.::.. : : .:: . .:: ..:::::.::. .. .. : . .. .: :.
XP_005 VFDAHDGEVNAVQFSPGS-RLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFD
190 200 210 220 230 240
350 360 370 380 390
pF1KB9 TAGTQFLSAAYDRYLKLWDTETGQCISRFTNR--KVPYCVKFNPDEDKQNLFVAGMSDKK
.::. .:.:. : ..: .. . .:.. :: .:: :. . .:.: :.
XP_005 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKV-LSAKFLLDNAR---IVSGSHDRT
250 260 270 280 290 300
400 410 420 430 440 450
pF1KB9 IVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEP
. ::.:: .. .. : :: ... .: ::..: : :: .
XP_005 LKLWDLRSKVCIKTV-FAGSSCNDIVCTEQC--VMSGHFDKKIRFW--DIRSESIVREME
310 320 330 340 350
460 470 480 490 500 510
pF1KB9 SMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNK-KKIFKGHMVAGYACQVD---
. .. :. :.:. : : :. . .. .: : :. :. . :. : :
XP_005 LLGKITALDLNPERTELLSCSRDDLLKVID----LRTNAIKQTFS---APGFKCGSDWTR
360 370 380 390 400 410
520 530 540 550 560 570
pF1KB9 --FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAV-WHPHETSKVITCGWD
:::: ::: .:...:.: ::. : :. . .. . . :.:: : : :.:..
XP_005 VVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPS-GSHVVSVDKG
420 430 440 450 460 470
pF1KB9 GLIKLWD
::
XP_005 CKAVLWAQY
480
579 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:49:48 2016 done: Sat Nov 5 18:49:50 2016
Total Scan time: 9.390 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]