Result of FASTA (omim) for
pF1KB9918
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9918, 579 aa
1>>>pF1KB9918 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.2266+/-0.000553; mu= -8.4989+/- 0.034
mean_var=607.3758+/-134.307, 0's: 0 Z-trim(118.2): 1526 B-trim: 0 in 0/59
Lambda= 0.052041
statistics sampled from 28734 (30883) to 28734 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.362), width: 16
Scan time: 8.650
The best scores are: opt bits E(85289)
NP_003179 (OMIM: 157800,602614,617137) mitogen-act ( 579) 3850 305.0 4.4e-82
NP_663306 (OMIM: 157800,602614,617137) mitogen-act ( 491) 3219 257.5 7.3e-68
XP_016866715 (OMIM: 157800,602614,617137) PREDICTE ( 449) 3015 242.1 2.8e-63
NP_663304 (OMIM: 157800,602614,617137) mitogen-act ( 606) 2728 220.8 1e-56
NP_663305 (OMIM: 157800,602614,617137) mitogen-act ( 518) 2715 219.7 1.9e-56
XP_006715616 (OMIM: 157800,602614,617137) PREDICTE ( 476) 1893 157.9 6.7e-38
NP_598407 (OMIM: 609479,616890) mitogen-activated ( 455) 571 58.7 5e-08
XP_016859813 (OMIM: 609479,616890) PREDICTED: mito ( 455) 571 58.7 5e-08
XP_016859812 (OMIM: 609479,616890) PREDICTED: mito ( 455) 571 58.7 5e-08
NP_057737 (OMIM: 609479,616890) mitogen-activated ( 800) 571 59.0 6.9e-08
XP_005246697 (OMIM: 609479,616890) PREDICTED: mito ( 800) 571 59.0 6.9e-08
XP_005269197 (OMIM: 600447) PREDICTED: mitogen-act ( 453) 535 55.9 3.2e-07
NP_006292 (OMIM: 600447) mitogen-activated protein ( 859) 535 56.3 4.7e-07
XP_016875445 (OMIM: 600447) PREDICTED: mitogen-act ( 859) 535 56.3 4.7e-07
XP_006719651 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 535 56.4 4.8e-07
NP_001180440 (OMIM: 600447) mitogen-activated prot ( 892) 535 56.4 4.8e-07
XP_011537027 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 535 56.4 4.8e-07
XP_005269195 (OMIM: 600447) PREDICTED: mitogen-act ( 892) 535 56.4 4.8e-07
NP_057062 (OMIM: 613932,616117) serine/threonine-p ( 835) 530 55.9 6e-07
XP_016862946 (OMIM: 604915) PREDICTED: mitogen-act ( 817) 519 55.1 1e-06
XP_016862945 (OMIM: 604915) PREDICTED: mitogen-act ( 966) 519 55.2 1.2e-06
XP_011511612 (OMIM: 604915) PREDICTED: mitogen-act ( 966) 519 55.2 1.2e-06
NP_004712 (OMIM: 604915) mitogen-activated protein ( 966) 519 55.2 1.2e-06
NP_001229243 (OMIM: 604915) mitogen-activated prot ( 966) 519 55.2 1.2e-06
NP_002437 (OMIM: 600137) mitogen-activated protein ( 954) 514 54.8 1.5e-06
XP_016864058 (OMIM: 600583) PREDICTED: tyrosine-pr ( 515) 483 52.1 5.2e-06
XP_011525284 (OMIM: 600137) PREDICTED: mitogen-act ( 860) 488 52.8 5.4e-06
XP_011512039 (OMIM: 600583) PREDICTED: tyrosine-pr ( 595) 483 52.2 5.6e-06
XP_011525283 (OMIM: 600137) PREDICTED: mitogen-act ( 962) 488 52.9 5.8e-06
NP_003206 (OMIM: 600583) tyrosine-protein kinase T ( 631) 483 52.2 5.8e-06
NP_002410 (OMIM: 600050) mitogen-activated protein ( 847) 479 52.1 8.5e-06
XP_005267740 (OMIM: 600136) PREDICTED: mitogen-act (1081) 481 52.4 8.9e-06
NP_001271159 (OMIM: 600136) mitogen-activated prot (1104) 481 52.4 9e-06
NP_149132 (OMIM: 600136) mitogen-activated protein (1118) 481 52.4 9.1e-06
XP_011535090 (OMIM: 600136) PREDICTED: mitogen-act (1166) 481 52.5 9.3e-06
NP_001273546 (OMIM: 611110) MAP3K7 C-terminal-like ( 142) 455 49.2 1e-05
NP_001273548 (OMIM: 611110) MAP3K7 C-terminal-like ( 142) 455 49.2 1e-05
NP_001273549 (OMIM: 611110) MAP3K7 C-terminal-like ( 142) 455 49.2 1e-05
NP_001273547 (OMIM: 611110) MAP3K7 C-terminal-like ( 142) 455 49.2 1e-05
XP_016864932 (OMIM: 186973,613011) PREDICTED: tyro ( 495) 467 50.9 1.2e-05
NP_005537 (OMIM: 186973,613011) tyrosine-protein k ( 620) 467 51.0 1.3e-05
NP_647611 (OMIM: 600038) megakaryocyte-associated ( 466) 453 49.8 2.3e-05
XP_011526320 (OMIM: 600038) PREDICTED: megakaryocy ( 507) 453 49.9 2.4e-05
NP_647612 (OMIM: 600038) megakaryocyte-associated ( 507) 453 49.9 2.4e-05
NP_002369 (OMIM: 600038) megakaryocyte-associated ( 508) 453 49.9 2.5e-05
NP_001273551 (OMIM: 611110) MAP3K7 C-terminal-like ( 136) 436 47.8 2.8e-05
NP_065690 (OMIM: 263650,605706) receptor-interacti ( 784) 448 49.7 4.1e-05
XP_011512050 (OMIM: 600058) PREDICTED: tyrosine-pr ( 289) 434 48.1 4.7e-05
XP_016864071 (OMIM: 600058) PREDICTED: tyrosine-pr ( 338) 434 48.2 5.2e-05
NP_001273563 (OMIM: 611110) MAP3K7 C-terminal-like ( 242) 428 47.5 5.8e-05
>>NP_003179 (OMIM: 157800,602614,617137) mitogen-activat (579 aa)
initn: 3850 init1: 3850 opt: 3850 Z-score: 1594.6 bits: 305.0 E(85289): 4.4e-82
Smith-Waterman score: 3850; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNGQPRRRSIQDLTVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNGQPRRRSIQDLTVTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 TEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 QPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRL
490 500 510 520 530 540
550 560 570
pF1KB9 VQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
:::::::::::::::::::::::::::::::::::::::
NP_003 VQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
550 560 570
>>NP_663306 (OMIM: 157800,602614,617137) mitogen-activat (491 aa)
initn: 3211 init1: 3211 opt: 3219 Z-score: 1339.3 bits: 257.5 E(85289): 7.3e-68
Smith-Waterman score: 3219; 99.2% identity (99.4% similar) in 486 aa overlap (1-486:1-486)
10 20 30 40 50 60
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNGQPRRRSIQDLTVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNGQPRRRSIQDLTVTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 TEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 TEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 QPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRL
: . :
NP_663 QARTSCRTGPG
490
>>XP_016866715 (OMIM: 157800,602614,617137) PREDICTED: m (449 aa)
initn: 3015 init1: 3015 opt: 3015 Z-score: 1256.9 bits: 242.1 E(85289): 2.8e-63
Smith-Waterman score: 3015; 100.0% identity (100.0% similar) in 449 aa overlap (131-579:1-449)
110 120 130 140 150 160
pF1KB9 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP
::::::::::::::::::::::::::::::
XP_016 MSWCLQCSQGVAYLHSMQPKALIHRDLKPP
10 20 30
170 180 190 200 210 220
pF1KB9 NLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILW
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 EVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB9 VKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPA
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB9 TNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB9 ATTGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATTGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDST
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB9 DTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRK
340 350 360 370 380 390
530 540 550 560 570
pF1KB9 QELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
400 410 420 430 440
>>NP_663304 (OMIM: 157800,602614,617137) mitogen-activat (606 aa)
initn: 2707 init1: 2707 opt: 2728 Z-score: 1139.1 bits: 220.8 E(85289): 1e-56
Smith-Waterman score: 3786; 95.5% identity (95.5% similar) in 606 aa overlap (1-579:1-606)
10 20 30 40 50 60
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
310 320 330 340 350 360
370 380 390 400
pF1KB9 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATT-----------------
:::::::::::::::::::::::::::::::::::::::::::
NP_663 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYSKPKRGHRKTASFGN
370 380 390 400 410 420
410 420 430 440 450
pF1KB9 ----------GNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 ILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB9 WTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 WTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB9 ALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 ALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQ
550 560 570 580 590 600
pF1KB9 KRQGTS
::::::
NP_663 KRQGTS
>>NP_663305 (OMIM: 157800,602614,617137) mitogen-activat (518 aa)
initn: 2731 init1: 2707 opt: 2715 Z-score: 1134.5 bits: 219.7 E(85289): 1.9e-56
Smith-Waterman score: 3155; 94.0% identity (94.2% similar) in 513 aa overlap (1-486:1-513)
10 20 30 40 50 60
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 AIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 DIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 WAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 PCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQ
310 320 330 340 350 360
370 380 390 400
pF1KB9 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATT-----------------
:::::::::::::::::::::::::::::::::::::::::::
NP_663 SESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYSKPKRGHRKTASFGN
370 380 390 400 410 420
410 420 430 440 450
pF1KB9 ----------GNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 ILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB9 WTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEI
:::::::::::::::::::::::::::: . :
NP_663 WTPDDSTDTNGSDNSIPMAYLTLDHQLQARTSCRTGPG
490 500 510
520 530 540 550 560 570
pF1KB9 ALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQ
>>XP_006715616 (OMIM: 157800,602614,617137) PREDICTED: m (476 aa)
initn: 1872 init1: 1872 opt: 1893 Z-score: 801.4 bits: 157.9 E(85289): 6.7e-38
Smith-Waterman score: 2951; 94.3% identity (94.3% similar) in 476 aa overlap (131-579:1-476)
110 120 130 140 150 160
pF1KB9 CLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP
::::::::::::::::::::::::::::::
XP_006 MSWCLQCSQGVAYLHSMQPKALIHRDLKPP
10 20 30
170 180 190 200 210 220
pF1KB9 NLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILW
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB9 EVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB9 VKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPA
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB9 TNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIA
220 230 240 250 260 270
410 420 430
pF1KB9 ATT---------------------------GNGQPRRRSIQDLTVTGTEPGQVSSRSSSP
::: ::::::::::::::::::::::::::::::
XP_006 ATTAYSKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSP
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB9 SVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESM
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB9 AVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKS
400 410 420 430 440 450
560 570
pF1KB9 LSTYYQQCKKQLEVIRSQQQKRQGTS
::::::::::::::::::::::::::
XP_006 LSTYYQQCKKQLEVIRSQQQKRQGTS
460 470
>>NP_598407 (OMIM: 609479,616890) mitogen-activated prot (455 aa)
initn: 418 init1: 259 opt: 571 Z-score: 265.2 bits: 58.7 E(85289): 5e-08
Smith-Waterman score: 593; 30.7% identity (58.6% similar) in 430 aa overlap (27-435:7-395)
10 20 30 40 50
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD-
.: .: . ... : : :.:: : .::: ..:
NP_598 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDK
10 20 30 40
60 70 80 90 100 110
pF1KB9 -VAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNP--VCLVMEYAEGGSLYNVL
::.:.. . :..: : :: ..: ::...::. :.: .: ::: ::::. .
NP_598 EVAVKKLL-KIEKEAEI-----LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI
50 60 70 80 90
120 130 140 150 160 170
pF1KB9 HGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDF
.. . . : :.: . ..:. ::: : .:::::: :....: : :::::::
NP_598 NSNRS-EEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADG-VLKICDF
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 GTACDIQTHMTNNK--GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGG
: : ...: :. . :. ::::::... :: ::..:.:..:::..::. :: . :
NP_598 G-ASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 PAFRIMW-AVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG
... : .:... : . .. :. . :. .:: : ..:::...:..:. . .
NP_598 --LQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM-----S
220 230 240 250 260
300 310 320 330 340 350
pF1KB9 ADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKL-
: : :. ::. ::.. : . :: . .:.:: :
NP_598 NDTSLPDKCN--------------SFLH-------NKAEWRCE-IEATLERLKKLERDLS
270 280 290 300
360 370 380 390 400
pF1KB9 LKNQAKQQSESGRLSLGASRGSSVESLP---PTS---------EGKRMSADMSEIEARIA
.:.: .. : ::.. .. . . : : . :.: .. .:. .:.
NP_598 FKEQELKERER-RLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQIT
310 320 330 340 350 360
410 420 430 440 450
pF1KB9 ATT-GNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDS
::. :.:. :.: . . : :.. : ... .:
NP_598 ATSNGEGHGMNPSLQAMMLMGF--GDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRG
370 380 390 400 410
460 470 480 490 500 510
pF1KB9 TDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQR
NP_598 KKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
420 430 440 450
>>XP_016859813 (OMIM: 609479,616890) PREDICTED: mitogen- (455 aa)
initn: 418 init1: 259 opt: 571 Z-score: 265.2 bits: 58.7 E(85289): 5e-08
Smith-Waterman score: 593; 30.7% identity (58.6% similar) in 430 aa overlap (27-435:7-395)
10 20 30 40 50
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD-
.: .: . ... : : :.:: : .::: ..:
XP_016 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDK
10 20 30 40
60 70 80 90 100 110
pF1KB9 -VAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNP--VCLVMEYAEGGSLYNVL
::.:.. . :..: : :: ..: ::...::. :.: .: ::: ::::. .
XP_016 EVAVKKLL-KIEKEAEI-----LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI
50 60 70 80 90
120 130 140 150 160 170
pF1KB9 HGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDF
.. . . : :.: . ..:. ::: : .:::::: :....: : :::::::
XP_016 NSNRS-EEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADG-VLKICDF
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 GTACDIQTHMTNNK--GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGG
: : ...: :. . :. ::::::... :: ::..:.:..:::..::. :: . :
XP_016 G-ASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 PAFRIMW-AVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG
... : .:... : . .. :. . :. .:: : ..:::...:..:. . .
XP_016 --LQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM-----S
220 230 240 250 260
300 310 320 330 340 350
pF1KB9 ADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKL-
: : :. ::. ::.. : . :: . .:.:: :
XP_016 NDTSLPDKCN--------------SFLH-------NKAEWRCE-IEATLERLKKLERDLS
270 280 290 300
360 370 380 390 400
pF1KB9 LKNQAKQQSESGRLSLGASRGSSVESLP---PTS---------EGKRMSADMSEIEARIA
.:.: .. : ::.. .. . . : : . :.: .. .:. .:.
XP_016 FKEQELKERER-RLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQIT
310 320 330 340 350 360
410 420 430 440 450
pF1KB9 ATT-GNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDS
::. :.:. :.: . . : :.. : ... .:
XP_016 ATSNGEGHGMNPSLQAMMLMGF--GDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRG
370 380 390 400 410
460 470 480 490 500 510
pF1KB9 TDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQR
XP_016 KKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
420 430 440 450
>>XP_016859812 (OMIM: 609479,616890) PREDICTED: mitogen- (455 aa)
initn: 418 init1: 259 opt: 571 Z-score: 265.2 bits: 58.7 E(85289): 5e-08
Smith-Waterman score: 593; 30.7% identity (58.6% similar) in 430 aa overlap (27-435:7-395)
10 20 30 40 50
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD-
.: .: . ... : : :.:: : .::: ..:
XP_016 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDK
10 20 30 40
60 70 80 90 100 110
pF1KB9 -VAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNP--VCLVMEYAEGGSLYNVL
::.:.. . :..: : :: ..: ::...::. :.: .: ::: ::::. .
XP_016 EVAVKKLL-KIEKEAEI-----LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI
50 60 70 80 90
120 130 140 150 160 170
pF1KB9 HGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDF
.. . . : :.: . ..:. ::: : .:::::: :....: : :::::::
XP_016 NSNRS-EEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADG-VLKICDF
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 GTACDIQTHMTNNK--GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGG
: : ...: :. . :. ::::::... :: ::..:.:..:::..::. :: . :
XP_016 G-ASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 PAFRIMW-AVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG
... : .:... : . .. :. . :. .:: : ..:::...:..:. . .
XP_016 --LQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM-----S
220 230 240 250 260
300 310 320 330 340 350
pF1KB9 ADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKL-
: : :. ::. ::.. : . :: . .:.:: :
XP_016 NDTSLPDKCN--------------SFLH-------NKAEWRCE-IEATLERLKKLERDLS
270 280 290 300
360 370 380 390 400
pF1KB9 LKNQAKQQSESGRLSLGASRGSSVESLP---PTS---------EGKRMSADMSEIEARIA
.:.: .. : ::.. .. . . : : . :.: .. .:. .:.
XP_016 FKEQELKERER-RLKMWEQKLTEQSNTPLLLPLAARMSEESYFESKTEESNSAEMSCQIT
310 320 330 340 350 360
410 420 430 440 450
pF1KB9 ATT-GNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDS
::. :.:. :.: . . : :.. : ... .:
XP_016 ATSNGEGHGMNPSLQAMMLMGF--GDIFSMNKAGAVMHSGMQINMQAKQNSSKTTSKRRG
370 380 390 400 410
460 470 480 490 500 510
pF1KB9 TDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQR
XP_016 KKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE
420 430 440 450
>>NP_057737 (OMIM: 609479,616890) mitogen-activated prot (800 aa)
initn: 418 init1: 259 opt: 571 Z-score: 262.6 bits: 59.0 E(85289): 6.9e-08
Smith-Waterman score: 573; 32.3% identity (59.8% similar) in 368 aa overlap (27-384:7-335)
10 20 30 40 50
pF1KB9 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD-
.: .: . ... : : :.:: : .::: ..:
NP_057 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDK
10 20 30 40
60 70 80 90 100 110
pF1KB9 -VAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNP--VCLVMEYAEGGSLYNVL
::.:.. . :..: : :: ..: ::...::. :.: .: ::: ::::. .
NP_057 EVAVKKLL-KIEKEAEI-----LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI
50 60 70 80 90
120 130 140 150 160 170
pF1KB9 HGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDF
.. . . : :.: . ..:. ::: : .:::::: :....: : :::::::
NP_057 NSNRS-EEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADG-VLKICDF
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 GTACDIQTHMTNNK--GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGG
: : ...: :. . :. ::::::... :: ::..:.:..:::..::. :: . :
NP_057 G-ASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 PAFRIMW-AVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG
... : .:... : . .. :. . :. .:: : ..:::...:..:. . .
NP_057 --LQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM-----S
220 230 240 250 260
300 310 320 330 340 350
pF1KB9 ADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKL-
: : : .::. ::.. : . :: . .:.:: :
NP_057 NDTSLPDKC--------------NSFL-------HNKAEWRCE-IEATLERLKKLERDLS
270 280 290 300
360 370 380 390 400 410
pF1KB9 LKNQAKQQSESGRLSLGASRGSSVESLP--PTSEGKRMSADMSEIEARIAATTGNGQPRR
.:.: .. : ::.. .. . . : :. :
NP_057 FKEQELKERER-RLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAEM
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB9 RSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTRSHPWTPDDSTDTNGSDNSIP
NP_057 SVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPLI
370 380 390 400 410 420
579 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:39:46 2016 done: Fri Nov 4 09:39:47 2016
Total Scan time: 8.650 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]