Result of FASTA (ccds) for
pF1KB9882
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9882, 613 aa
1>>>pF1KB9882 613 - 613 aa - 613 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1927+/-0.000891; mu= 8.9473+/- 0.054
mean_var=225.8457+/-44.704, 0's: 0 Z-trim(115.3): 52 B-trim: 111 in 1/52
Lambda= 0.085343
statistics sampled from 15796 (15848) to 15796 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.487), width: 16
Scan time: 4.450
The best scores are: opt bits E(32554)
CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 ( 613) 4157 524.6 1.4e-148
CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 ( 529) 1247 166.3 9.3e-41
CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 ( 653) 1216 162.6 1.5e-39
CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 ( 456) 1118 150.3 5e-36
CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 ( 575) 990 134.7 3.3e-31
CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 ( 356) 932 127.3 3.3e-29
CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 ( 499) 932 127.5 4.2e-29
CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 ( 495) 928 127.0 5.9e-29
CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 ( 511) 838 115.9 1.3e-25
CCDS6209.1 KCNB2 gene_id:9312|Hs108|chr8 ( 911) 694 98.4 4.2e-20
CCDS13418.1 KCNB1 gene_id:3745|Hs108|chr20 ( 858) 682 96.9 1.1e-19
CCDS13342.1 KCNS1 gene_id:3787|Hs108|chr20 ( 526) 618 88.8 1.9e-17
CCDS13436.1 KCNG1 gene_id:3755|Hs108|chr20 ( 513) 615 88.5 2.4e-17
CCDS1692.1 KCNS3 gene_id:3790|Hs108|chr2 ( 491) 605 87.2 5.5e-17
CCDS1676.1 KCNF1 gene_id:3754|Hs108|chr2 ( 494) 568 82.7 1.3e-15
CCDS6314.1 KCNV1 gene_id:27012|Hs108|chr8 ( 500) 567 82.5 1.4e-15
CCDS10945.1 KCNG4 gene_id:93107|Hs108|chr16 ( 519) 562 81.9 2.2e-15
CCDS12019.1 KCNG2 gene_id:26251|Hs108|chr18 ( 466) 542 79.4 1.1e-14
CCDS42674.1 KCNG3 gene_id:170850|Hs108|chr2 ( 425) 541 79.3 1.2e-14
CCDS1809.1 KCNG3 gene_id:170850|Hs108|chr2 ( 436) 535 78.5 2e-14
CCDS6447.1 KCNV2 gene_id:169522|Hs108|chr9 ( 545) 534 78.5 2.5e-14
CCDS14314.1 KCND1 gene_id:3750|Hs108|chrX ( 647) 510 75.6 2.2e-13
CCDS5776.1 KCND2 gene_id:3751|Hs108|chr7 ( 630) 509 75.5 2.4e-13
CCDS7827.1 KCNC1 gene_id:3746|Hs108|chr11 ( 511) 505 74.9 2.9e-13
CCDS44547.1 KCNC1 gene_id:3746|Hs108|chr11 ( 585) 505 75.0 3.2e-13
CCDS844.1 KCND3 gene_id:3752|Hs108|chr1 ( 636) 505 75.0 3.3e-13
CCDS843.1 KCND3 gene_id:3752|Hs108|chr1 ( 655) 505 75.0 3.4e-13
CCDS12793.1 KCNC3 gene_id:3748|Hs108|chr19 ( 757) 499 74.3 6.3e-13
CCDS9006.1 KCNC2 gene_id:3747|Hs108|chr12 ( 558) 495 73.7 7.2e-13
CCDS58255.1 KCNC2 gene_id:3747|Hs108|chr12 ( 583) 495 73.7 7.4e-13
CCDS9005.1 KCNC2 gene_id:3747|Hs108|chr12 ( 613) 495 73.8 7.6e-13
CCDS58257.1 KCNC2 gene_id:3747|Hs108|chr12 ( 618) 495 73.8 7.7e-13
CCDS58256.1 KCNC2 gene_id:3747|Hs108|chr12 ( 629) 495 73.8 7.8e-13
CCDS9007.1 KCNC2 gene_id:3747|Hs108|chr12 ( 638) 495 73.8 7.9e-13
CCDS44193.1 KCNC4 gene_id:3749|Hs108|chr1 ( 626) 492 73.4 1e-12
CCDS821.1 KCNC4 gene_id:3749|Hs108|chr1 ( 635) 492 73.4 1e-12
>>CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 (613 aa)
initn: 4157 init1: 4157 opt: 4157 Z-score: 2780.8 bits: 524.6 E(32554): 1.4e-148
Smith-Waterman score: 4157; 100.0% identity (100.0% similar) in 613 aa overlap (1-613:1-613)
10 20 30 40 50 60
pF1KB9 MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
550 560 570 580 590 600
610
pF1KB9 YALCLDTSRETDL
:::::::::::::
CCDS85 YALCLDTSRETDL
610
>>CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 (529 aa)
initn: 1777 init1: 945 opt: 1247 Z-score: 845.2 bits: 166.3 E(32554): 9.3e-41
Smith-Waterman score: 2056; 70.3% identity (81.0% similar) in 468 aa overlap (86-531:12-473)
60 70 80 90 100 110
pF1KB9 AQRDADSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGD-PGLGTVEDQALGT
: : : .... :: : : :
CCDS85 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGG------GG
10 20 30
120 130 140 150 160 170
pF1KB9 ASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDG
. .:. :::::::::::: ::. ::.::::::..:.:.::::::::::::::::::.
CCDS85 GCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDA
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB9 ILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKE---EEKPLPRNE
::::::::::::::::: ::.: .:::::::::::. :::::: . : .::::: .
CCDS85 ILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQP
100 110 120 130 140 150
240 250 260 270 280
pF1KB9 FQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFR-DERE-----LLRHP
:::::::.:::::::: ::.:::::::::::::. :::::::.:: : : . :
CCDS85 FQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVS
160 170 180 190 200 210
290 300 310 320 330
pF1KB9 PAPHQPPAPAPGANGS---------GVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFT
:. . . : : :. .. ... : ..::::.::: :..:::
CCDS85 PVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFT
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB9 FELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELA---EQQPGGGGGGQNGQQA
::::::: ::::: .: ::::::::.::::::::::::::. ::::..::::::::::
CCDS85 FELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB9 MSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 MSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVY
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB9 FAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVP
:::::.. . : ::::::::::::::::::::: :.::::::::::::::::::::::::
CCDS85 FAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVP
400 410 420 430 440 450
520 530 540 550 560 570
pF1KB9 VIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENA
::::::::::::::..::
CCDS85 VIVSNFNYFYHRETEQEEQGQYTHVTCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPT
460 470 480 490 500 510
>>CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 (653 aa)
initn: 2147 init1: 877 opt: 1216 Z-score: 823.5 bits: 162.6 E(32554): 1.5e-39
Smith-Waterman score: 2064; 57.7% identity (74.9% similar) in 610 aa overlap (13-589:41-632)
10 20 30 40
pF1KB9 MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGL
: .: .. : : : . :: . . :
CCDS41 SGCNSHMPYGYAAQARARERERLAHSRAAAAAAVAAATAAVEGSGGSGGGSHHHHQSRGA
20 30 40 50 60 70
50 60 70 80 90
pF1KB9 SDGPKEPAPKG-------RGAQRDADSGVRPLPPLPD--PG---VRPLPPLPEELPRPRR
. . .: :. .. : .: : :. . : : :: . .
CCDS41 CTSHDPQSSRGSRRRRRQRSEKKKAHYRQSSFPHCSDLMPSGSEEKILRELSEE--EEDE
80 90 100 110 120
100 110 120 130
pF1KB9 PPPEDEEEEG-------DPG-------LGTVEDQALGTASLHH----QRVHINISGLRFE
:.::::: : : : .. . : .:... .:: ::.::::::
CCDS41 EEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYSDCCERVVINVSGLRFE
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB9 TQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVS
::. ::::::.:::::: :: .:::::::::::::::::::.:::::::::::.:::::
CCDS41 TQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVP
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB9 LDVFADEIRFYQLGDEAMERFREDEGFIKEEE-KPLPRNEFQRQVWLIFEYPESSGSARA
.:.:..:..:::::.::. .:::::::..::: . ::.:::..:.::.:::::::. ::.
CCDS41 FDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARG
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB9 IAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPT
:::::::::::::. :::::::::::.:.:. : . :..: :.. :.:
CCDS41 IAIVSVLVILISIVIFCLETLPEFRDDRDLVM---------ALSAGGHG-GLLNDTSAPH
310 320 330 340 350
320 330 340 350 360 370
pF1KB9 VAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFIT
. . ::::::::.:..::.::..:: :::::.: : .:::::::.:.:.:::::
CCDS41 LENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFIT
360 370 380 390 400 410
380 390 400 410 420 430
pF1KB9 LGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASM
:::.::.:: :::.::. :::::.::::.:::::::::::::::::::::::.::.:::
CCDS41 LGTDLAQQQ--GGGNGQQ-QQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASM
420 430 440 450 460 470
440 450 460 470 480 490
pF1KB9 RELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITV
:::::::::::::::::::::::::::. :::.:::::::::::::::::::::.::::
CCDS41 RELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITV
480 490 500 510 520 530
500 510 520 530 540 550
pF1KB9 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRG
::::::::::::::::::::::::::::::::::::..:: . : :.. : : : .
CCDS41 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLT--QNAVSC-PYLPSN
540 550 560 570 580 590
560 570 580 590 600
pF1KB9 VQRKV-SGSRGSFCKAGGTLENADSARRGSCPLE-KCNVKAKSNVDLRRSLYALCLDTSR
. .: :.. .:. . :: ...... : : ::. :
CCDS41 LLKKFRSSTSSSLGDKSEYLEMEEGVKESLCAKEEKCQGKGDDSETDKNNCSNAKAVETD
600 610 620 630 640 650
610
pF1KB9 ETDL
CCDS41 V
>>CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 (456 aa)
initn: 1886 init1: 824 opt: 1118 Z-score: 760.2 bits: 150.3 E(32554): 5e-36
Smith-Waterman score: 1865; 67.0% identity (83.6% similar) in 427 aa overlap (120-546:13-423)
90 100 110 120 130 140
pF1KB9 RPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDP
.:. .:..::::::. ::..::.::::::
CCDS12 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDP
10 20 30 40
150 160 170 180 190 200
pF1KB9 AKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEA
:.: :..: : ::::::.:::::..:::::::::::::..: :::: .:. :: :: :
CCDS12 ARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGAAA
50 60 70 80 90 100
210 220 230 240 250 260
pF1KB9 MERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCL
. :.::::: :.:::: : ::.::.::.:::: .::..:.:::::::.::..:::
CCDS12 LARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCL
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB9 ETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVET
::::.:::.:. : : ::: :::. : :..: : :: . ::::.:::
CCDS12 ETLPDFRDDRDGTGLAAAAAAGPFPAP-LNGSSQM--PGNP---PRLP--FNDPFFVVET
170 180 190 200 210
330 340 350 360 370 380
pF1KB9 TCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQN
:. ::.::::::...::::: : .:.::.:: :::.:::..::::::.:. :
CCDS12 LCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQR----G---V
220 230 240 250 260
390 400 410 420 430 440
pF1KB9 GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFS
:::::::::::::::::::::::::::::::::::.::.:::::::::::::::::.:::
CCDS12 GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFS
270 280 290 300 310 320
450 460 470 480 490 500
pF1KB9 SAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIA
:::::::.: .::.:::..:::::::::::::::: :.:::::::::::::::::::.
CCDS12 SAVYFAEVDRVDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTIS
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB9 LPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKAGGT
::::::::::.:::::::. :: ..... . : ::
CCDS12 LPVPVIVSNFSYFYHRETEGEEAGMFSHVD-MQPCGPLEGKANGGLVDGEVPELPPPLWA
390 400 410 420 430 440
570 580 590 600 610
pF1KB9 LENADSARRGSCPLEKCNVKAKSNVDLRRSLYALCLDTSRETDL
CCDS12 PPGKHLVTEV
450
>>CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 (575 aa)
initn: 1769 init1: 930 opt: 990 Z-score: 673.8 bits: 134.7 E(32554): 3.3e-31
Smith-Waterman score: 2148; 68.5% identity (79.3% similar) in 511 aa overlap (37-531:13-495)
10 20 30 40 50 60
pF1KB9 PLENGGAMTVRGGDEARAGCGQATGGELQCPPTA-GLSDGPKEPAPKGRGAQRDADSGV-
::.: . :..:: .: ::. .. :
CCDS82 MDERLSLLRSPPPPSARHRAHPPQRPASSG-GAHTLVNHGYA
10 20 30 40
70 80 90 100 110
pF1KB9 -----RPLPPLPDPGVRPLPPLPE-ELPRPRRPPPE--------DEEEEGDPGLGTVEDQ
: ::: : : : : : :. ::. :. : :.:
CCDS82 EPAAGRELPP--DMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSL-----P
50 60 70 80 90
120 130 140 150 160 170
pF1KB9 ALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRP
: : . .:: :::::::::::: :: :::.:::::: .:.:::::::::::::::::
CCDS82 AAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRP
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 SFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRN
:::.::::::::::.:::::: .:.:..::::::::.::::.:::::::..:::.::::
CCDS82 SFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRR
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 EFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQ
.:::::::.:::::::: ::.:::::::::::::. ::::::::::::.. .: . :
CCDS82 DFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKD---YPASTSQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 PPAPAPGANGSGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKA
: : . :: : : ...::::.::: :.:::.::::::::::::::
CCDS82 DSFEAAGNSTSGSRAGAS----------SFSDPFFVVETLCIIWFSFELLVRFFACPSKA
280 290 300 310 320
360 370 380 390 400 410
pF1KB9 GFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRI
:::::::.::.:::.::::::::::::.: : ::::::::::::::::::::::
CCDS82 TFSRNIMNLIDIVAIIPYFITLGTELAERQ--G-----NGQQAMSLAILRVIRLVRVFRI
330 340 350 360 370
420 430 440 450 460 470
pF1KB9 FKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDA
::::::::::::::.::.::::::::::::::::::::::::::::::. . :::::::
CCDS82 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDA
380 390 400 410 420 430
480 490 500 510 520 530
pF1KB9 FWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHE
::::::::::::::::.:.:.::::::::::::::::::::::::::::::::::::. :
CCDS82 FWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGE
440 450 460 470 480 490
540 550 560 570 580 590
pF1KB9 EPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKA
:
CCDS82 EQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTA
500 510 520 530 540 550
>>CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 (356 aa)
initn: 1363 init1: 930 opt: 932 Z-score: 637.8 bits: 127.3 E(32554): 3.3e-29
Smith-Waterman score: 1339; 67.7% identity (81.8% similar) in 313 aa overlap (120-431:33-323)
90 100 110 120 130 140
pF1KB9 RPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDP
.:: :::::::::::: ::::::.::::::
CCDS55 VATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDP
10 20 30 40 50 60
150 160 170 180 190 200
pF1KB9 AKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEA
::.::::::::::::::::::::.::::::::::::::::: ::.:..:::::.::.::
CCDS55 KKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEA
70 80 90 100 110 120
210 220 230 240 250 260
pF1KB9 MERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCL
:: ::::::.:::::.:::.:::::::::.:::::::: :: ::::::.::::::..:::
CCDS55 MEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCL
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB9 ETLPEFRDERELLRHPPAPHQPPAPAPGANGSGV-MAPPSGPTVAPLLPRTLADPFFIVE
:::: :::: : . .:::: . :. :.. ...:::::::
CCDS55 ETLPIFRDENEDM----------------HGSGVTFHTYSNSTIGYQQSTSFTDPFFIVE
190 200 210 220
330 340 350 360 370 380
pF1KB9 TTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQ
: :.:::.::.::::::::::::: :::::::.:::.::::::::::::. . :
CCDS55 TLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDA----Q
230 240 250 260 270 280
390 400 410 420 430 440
pF1KB9 NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILF
.::::::::::::::: : : .. .. ..: : :. . . ..
CCDS55 QGQQAMSLAILRVIRLER--RPLQSQKSKRGRQHLNTSHDCTLGINLVAGMTVQWTRASG
290 300 310 320 330 340
450 460 470 480 490 500
pF1KB9 SSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTI
CCDS55 PDDRQTPAVTTLHRMY
350
>>CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 (499 aa)
initn: 2085 init1: 932 opt: 932 Z-score: 636.0 bits: 127.5 E(32554): 4.2e-29
Smith-Waterman score: 2072; 77.3% identity (87.5% similar) in 415 aa overlap (120-533:33-427)
90 100 110 120 130 140
pF1KB9 RPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDP
.:: :::::::::::: ::::::.::::::
CCDS82 VATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLGDP
10 20 30 40 50 60
150 160 170 180 190 200
pF1KB9 AKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEA
::.::::::::::::::::::::.::::::::::::::::: ::.:..:::::.::.::
CCDS82 KKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEA
70 80 90 100 110 120
210 220 230 240 250 260
pF1KB9 MERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCL
:: ::::::.:::::.:::.:::::::::.:::::::: :: ::::::.::::::..:::
CCDS82 MEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCL
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB9 ETLPEFRDERELLRHPPAPHQPPAPAPGANGSGV-MAPPSGPTVAPLLPRTLADPFFIVE
:::: :::: : . .:::: . :. :.. ...:::::::
CCDS82 ETLPIFRDENEDM----------------HGSGVTFHTYSNSTIGYQQSTSFTDPFFIVE
190 200 210 220
330 340 350 360 370 380
pF1KB9 TTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQ
: :.:::.::.::::::::::::: :::::::.:::.::::::::::::. . :
CCDS82 TLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDA----Q
230 240 250 260 270 280
390 400 410 420 430 440
pF1KB9 NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILF
.:::::::::::::::::::::::::::::::::::.::.::::::::::::::::::::
CCDS82 QGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILF
290 300 310 320 330 340
450 460 470 480 490 500
pF1KB9 SSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTI
::::::::::.. ..: :::::::::::.::::::::: : :.:::::::::::::::::
CCDS82 SSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTI
350 360 370 380 390 400
510 520 530 540 550 560
pF1KB9 ALPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKAGG
:::::::::::::::::::. :: :
CCDS82 ALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQ
410 420 430 440 450 460
>>CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 (495 aa)
initn: 2056 init1: 918 opt: 928 Z-score: 633.3 bits: 127.0 E(32554): 5.9e-29
Smith-Waterman score: 2042; 69.5% identity (83.3% similar) in 462 aa overlap (100-559:17-448)
70 80 90 100 110 120
pF1KB9 LPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGL
: : :. :: .:: ::::::
CCDS85 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGL
10 20 30 40
130 140 150 160 170 180
pF1KB9 RFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPV
:::::: :::::::::::.: ::.::::::::::::::::::::.:::::::::::::::
CCDS85 RFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
50 60 70 80 90 100
190 200 210 220 230 240
pF1KB9 NVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSA
:: ::.:..::.::.::.::::.::::::::::::.:::..:.::::::.:::::::: :
CCDS85 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPA
110 120 130 140 150 160
250 260 270 280 290 300
pF1KB9 RAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSG
:.::::::.::::::. ::::::::..:.... .:.. ..
CCDS85 RVIAIVSVMVILISIVIFCLETLPELKDDKDF-------------------TGTVHRIDN
170 180 190 200
310 320 330 340 350 360
pF1KB9 PTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYF
:: ..:::::::: :.:::.:::.:::::::::. : .::::.::.:::.:::
CCDS85 TTVI-YNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYF
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB9 ITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQA
::::::.:::. :.:.:.:: ::::::::::::::::::::::::::::::.::.:
CCDS85 ITLGTEIAEQE-----GNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKA
270 280 290 300 310 320
430 440 450 460 470 480
pF1KB9 SMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPI
::::::::::::::::::::::::::::.. .::::::::::::::.::::::::: :.
CCDS85 SMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPV
330 340 350 360 370 380
490 500 510 520 530 540
pF1KB9 TVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGL-
:.::::::::::::::::::::::::::::::::::::. :: : : . ..:.:
CCDS85 TIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQA-----QLLHVSSPNLA
390 400 410 420 430
550 560 570 580 590 600
pF1KB9 -DRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSLYALCLDT
: ..:. :..
CCDS85 SDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTTANQNCVNKSKLLTDV
440 450 460 470 480 490
>>CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 (511 aa)
initn: 1662 init1: 835 opt: 838 Z-score: 573.3 bits: 115.9 E(32554): 1.3e-25
Smith-Waterman score: 1872; 69.4% identity (84.3% similar) in 415 aa overlap (119-531:85-472)
90 100 110 120 130 140
pF1KB9 RRPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGD
.::: :::.:::::::: ::.:::.:::::
CCDS82 ESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLSQFPETLLGD
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB9 PAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDE
::...:: .::::::::::::::::::::::::..:::.:: .:.::::: ::.::.:
CCDS82 REKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDIFADEISFYELGSE
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB9 AMERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFC
::..:::::::::. : :: :...:: ::.:::::::..:::.:.:::::..::: ::
CCDS82 AMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPESSSAARAVAVVSVLVVVISITIFC
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB9 LETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSGPTVAPLLPRTL-ADPFFIV
::::::::..::: :. :. .: .:. .::::.:
CCDS82 LETLPEFREDREL--------------------KVVRDPNLNMSKTVLSQTMFTDPFFMV
240 250 260 270
330 340 350 360 370 380
pF1KB9 ETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELA-EQQPGGGGG
:.::..::::::..:: .::::. : ::::::::...:.::: :: :::. : .:
CCDS82 ESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELVQETEP-----
280 290 300 310 320
390 400 410 420 430 440
pF1KB9 GQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVI
..:: :::::::.:::::::::::::::::::::::.::.::::::::::::::::::
CCDS82 --SAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVI
330 340 350 360 370 380
450 460 470 480 490 500
pF1KB9 LFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVL
::::::::::.:. .:::::::.:::::::::::::::: : : ::::::.::::::::
CCDS82 LFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVL
390 400 410 420 430 440
510 520 530 540 550 560
pF1KB9 TIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKA
:::::::::::::::::::::..::
CCDS82 TIALPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTE
450 460 470 480 490 500
>>CCDS6209.1 KCNB2 gene_id:9312|Hs108|chr8 (911 aa)
initn: 928 init1: 517 opt: 694 Z-score: 474.3 bits: 98.4 E(32554): 4.2e-20
Smith-Waterman score: 853; 36.2% identity (63.6% similar) in 492 aa overlap (120-576:35-482)
90 100 110 120 130 140
pF1KB9 RPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGLRFETQLGTLAQFPNTLLGD-
.::.::..:: :. :: ..: : ::
CCDS62 APPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKL
10 20 30 40 50 60
150 160 170 180 190
pF1KB9 -----PAKRLRYFDPL---RNEYFFDRNRPSFDGILYYYQSGG--RLRRPVNVS----LD
. :. : .:::::::. .: .:: .:..: ... .: ::
CCDS62 RDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELD
70 80 90 100 110 120
200 210 220 230 240
pF1KB9 VFA-DEI--------RFYQLGDEAMERFREDEGFIKEEEKPLPRN----EFQRQVWLIFE
.. ::: :..: .. :..:.. ..:.: : . ....: ..:
CCDS62 YWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLWDLLE
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB9 YPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGS
:.:: .:. .::::.: :..: :.. :.::::... :.
CCDS62 KPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEF--------------------
190 200 210 220
310 320 330 340 350 360
pF1KB9 GVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIID
: . : :: ::..:. :::.: :.::.. :.: : .. .:.::
CCDS62 GQLNDN----------RQLAH----VEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVID
230 240 250 260 270
370 380 390 400 410 420
pF1KB9 VVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLA-ILRVIRLVRVFRIFKLSRHSKGL
..::.::..:. :.:.. .. : ... .....:..:..::.::.::: ::
CCDS62 LLAILPYYVTI--FLTESN-------KSVLQFQNVRRVVQIFRIMRILRILKLARHSTGL
280 290 300 310 320
430 440 450 460 470 480
pF1KB9 QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
: :: ::. :. ::::::.:: .:...::: :.::: :...:.:.::: .::::..::::
CCDS62 QSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATKFTSIPASFWWATITMTT
330 340 350 360 370 380
490 500 510 520 530 540
pF1KB9 VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
:::::. : :. :::::.:: :::::.::::.:.::.::. :: .: ..: :. ..:
CCDS62 VGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFY-KEQKRQEKAIKRREAL
390 400 410 420 430 440
550 560 570 580 590
pF1KB9 TQSQGPGLDRGVQRKVSGSRG------SFCKAGGTLENADSARRGSCPLEKCNVKAKSNV
... : ... : . .:. . ::: . .. :::
CCDS62 ERAKRNGSIVSMNLKDAFARSMELIDVAVEKAGESANTKDSADDNHLSPSRWKWARKALS
450 460 470 480 490 500
600 610
pF1KB9 DLRRSLYALCLDTSRETDL
CCDS62 ETSSNKSFENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKLEMLYNEITKTQPHSHPNPDC
510 520 530 540 550 560
613 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:58:27 2016 done: Fri Nov 4 19:58:28 2016
Total Scan time: 4.450 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]