Result of FASTA (omim) for
pF1KB9881
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9881, 599 aa
1>>>pF1KB9881 599 - 599 aa - 599 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6291+/-0.000425; mu= 0.0796+/- 0.027
mean_var=348.5910+/-68.167, 0's: 0 Z-trim(121.7): 111 B-trim: 318 in 1/60
Lambda= 0.068694
statistics sampled from 38492 (38658) to 38492 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.754), E-opt: 0.2 (0.453), width: 16
Scan time: 13.430
The best scores are: opt bits E(85289)
NP_001801 (OMIM: 117140) major centromere autoanti ( 599) 3961 406.9 1e-112
NP_663761 (OMIM: 612973) tigger transposable eleme ( 525) 355 49.4 3.5e-05
NP_001030025 (OMIM: 300029,300455,300834,304020,31 (1152) 313 45.7 0.0011
NP_149985 (OMIM: 612969) tigger transposable eleme ( 549) 276 41.6 0.0083
>>NP_001801 (OMIM: 117140) major centromere autoantigen (599 aa)
initn: 3961 init1: 3961 opt: 3961 Z-score: 2144.7 bits: 406.9 E(85289): 1e-112
Smith-Waterman score: 3961; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599)
10 20 30 40 50 60
pF1KB9 MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVP
490 500 510 520 530 540
550 560 570 580 590
pF1KB9 VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS
550 560 570 580 590
>>NP_663761 (OMIM: 612973) tigger transposable element-d (525 aa)
initn: 454 init1: 147 opt: 355 Z-score: 214.0 bits: 49.4 E(85289): 3.5e-05
Smith-Waterman score: 484; 29.8% identity (59.2% similar) in 426 aa overlap (1-395:2-396)
10 20 30 40 50
pF1KB9 MGPKRRQ-LTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAIL----A
.: ..: ::...: ::...::. ...: .. ..: ::. : :::. :. .
NP_663 MLGKRKRVVLTIKDKLDIIKKLEEGISFKKLSVV--YGIGESTVRDIKKNKERIINYANS
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 SERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMD
:. ::.. ::. : : :..:. ..: ::.: .. :.::.: : ..: . . :::.
NP_663 SDPTSGVSK--RKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGME
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 -DFTASNGWLDRFRRRHGVVSCSGVA-RARARNAAPRTPAAPASPAAVPSEGSGGSTTGW
::.::.::: ::..:::. . .: . . .. ..: : :: .
NP_663 GDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAAREFC--------------GSFQEF
120 130 140 150 160
180 190 200 210 220 230
pF1KB9 RAREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRP--RQATQRLSVLLC
.:. : .....: .:.:.. ::... : .. :.. .:. .. :
NP_663 VEKENLQP--------EQIYGADQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCC
170 180 190 200 210
240 250 260 270
pF1KB9 ANADGSEKLPPLVAGKSAKPRAGQ----AGLPCDYTANSKGG-----VTTQALAKYL---
::: : .:: :.::. :::: . ..:: : .. ::. : : . ::.
NP_663 ANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQ-KGAWIEQSVFRQWFEKYFVPQ
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB9 --KALDTRMAAESRRVLLL---AGRLAAQSLDTSGLRHVQLAFFPPGT---VHPLERGVV
: : .. : . :::: .: . :... : . . ..::.. ..:. .::.
NP_663 VQKHLKSKGLLE-KAVLLLDFPPARPNEEMLSSDDGR-IIVKYLPPNVTSLIQPMSQGVL
280 290 300 310 320 330
340 350 360 370 380
pF1KB9 QQVKGHYRQAMLLKAMAALEGQDPSGLQLGLT--EALHFVAAAWQAVEPSDIAACFREAG
:: .:: ..: : : ::.::. . .:: .:.. :. ::. :. : :. ...
NP_663 ATVKRYYRAGLLQKYMD--EGNDPKIFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLF
340 350 360 370 380
390 400 410 420 430 440
pF1KB9 FGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEV
:. :.
NP_663 PGNEENSGMNIDEGAILAANLATVLQNTEECEHVDIENIDQWFDSRSSDSSCQVLTDSES
390 400 410 420 430 440
>>NP_001030025 (OMIM: 300029,300455,300834,304020,312610 (1152 aa)
initn: 676 init1: 259 opt: 313 Z-score: 187.4 bits: 45.7 E(85289): 0.0011
Smith-Waterman score: 317; 46.7% identity (65.8% similar) in 152 aa overlap (402-537:821-971)
380 390 400 410 420 430
pF1KB9 WQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEE-EEEEGEGEEEEEEGE
...::.:::::: : ::::::::::: :::
NP_001 GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGE
800 810 820 830 840 850
440 450 460 470
pF1KB9 EEEEEG--------GEGEELGEEEE---VEEEGDVDSDEEEE---EDEESSSEGLEAEDW
::: :: ::::: ::: : ::::. ...:: : :.::. .:: : :
NP_001 EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG-EEEGE
860 870 880 890 900
480 490 500 510 520 530
pF1KB9 AQGVVEAGGSFGAYGAQEEAQCPTLHFLEG-GEDSDSDSEEEDDEEEDDEDEDDDDDEED
..: : : . : ..: . :: :::.....:::. : : .:.: . . ::.
NP_001 GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE
910 920 930 940 950 960
540 550 560 570 580 590
pF1KB9 GDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGL
:.
NP_001 GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE
970 980 990 1000 1010 1020
>>NP_149985 (OMIM: 612969) tigger transposable element-d (549 aa)
initn: 439 init1: 205 opt: 276 Z-score: 171.4 bits: 41.6 E(85289): 0.0083
Smith-Waterman score: 398; 26.1% identity (52.4% similar) in 498 aa overlap (4-451:6-474)
10 20 30 40 50
pF1KB9 MGPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERK
: :...:: ......: . .:.. . .:.: ::. : :::. :: :
NP_149 MNKRGKYTTLNLEEKMKVLSRIEAGRSLKS--VMDEFGISKSTFYDIKKNKKLILDFVLK
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 YG---VASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDD
:.. :: . . : .. . :.:: :.::.::.:. :. : :.:. .: :
NP_149 QDMPLVGAEKRKRTTGAKYGDVDDAVYMWYQQKRSAGVPVRGVELQAAAERFARCFGRTD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 FTASNGWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAR
: ::.::: ::: ::.. : :.. . . .: . : . . . .
NP_149 FKASTGWLFRFRNRHAI----G-----NRKGCGEQVLSSVSENVEPFR----QKLSMIIK
120 130 140 150 160
180 190 200 210 220 230
pF1KB9 EEQPPSVAEGYASQDVFSATETSLWYDFLPD--QAA--GLCGGDGRPRQATQRLSVLLCA
::. ...:. ::.:.. .:. ::. .: :. . .:::..:::
NP_149 EEK-------LCLAQLYSGDETDLFWKSMPENSQASRKDICL-PGK-KINKERLSAFLCA
170 180 190 200 210
240 250 260 270
pF1KB9 NADGSEKLPPLVAGKSAKPRAGQ---AGLPCDYTANSKGGVTTQALA-----------KY
::::..:: .. ::: :.. . . :: : .. : . .. ..
NP_149 NADGTHKLKSIIIGKSKLPKSVKEDTSTLPVIYKPSKDVWFTRELFSEWFFQNFVPEVRH
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB9 LKALDTRMAAESRRVLLLAGRLAA----QSLDTSGLRHVQLAFFPPGT---VHPLERGVV
.. :. :. :.::: : .:: . : .. ::: .: ..:...::.
NP_149 FQLNVLRFHDEDVRALLLLDSCPAHPSSESLTSEDGR-IKCMFFPHNTSTLIQPMNQGVI
280 290 300 310 320 330
340 350 360 370 380
pF1KB9 QQVKGHYRQAMLLKAMAALEGQDP---------SGLQL-GLTEALHFVAAAWQAVEPSDI
. : :: .: .... .: .: : ... .. :. : .:. :. :
NP_149 LSCKRLYRWKQLEESLVIFEESDDEQEKGDKGVSKIKIYNIKSAIFNWAKSWEEVKQITI
340 350 360 370 380 390
390 400 410 420 430
pF1KB9 AACFR--------EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE
: .. : : : .. :.. :: : . .... .:. ::.:
NP_149 ANAWENLLYKKEPEYDFQGLEHGDYREILEKCGELETKLDDDRVWLNGD----EEKGCLL
400 410 420 430 440 450
440 450 460 470 480
pF1KB9 EEEGGEGEEL----GEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFG
. .:: .:. :: :. :
NP_149 KTKGGITKEVVQKGGEAEKQTAEFKLSAVRESLDYLLDFVDATPEFQRFHFTLKEMQQEI
460 470 480 490 500 510
599 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:18:37 2016 done: Fri Nov 4 20:18:39 2016
Total Scan time: 13.430 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]