Result of FASTA (omim) for
pF1KB9872
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9872, 495 aa
1>>>pF1KB9872 495 - 495 aa - 495 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9488+/-0.000477; mu= 20.6717+/- 0.029
mean_var=109.0851+/-22.859, 0's: 0 Z-trim(111.4): 220 B-trim: 149 in 1/50
Lambda= 0.122798
statistics sampled from 19543 (19939) to 19543 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.234), width: 16
Scan time: 9.320
The best scores are: opt bits E(85289)
NP_000208 (OMIM: 160120,176260) potassium voltage- ( 495) 3258 588.9 1.1e-167
XP_011539699 (OMIM: 176262,616366) PREDICTED: pota ( 499) 2596 471.6 2.2e-132
XP_011539700 (OMIM: 176262,616366) PREDICTED: pota ( 499) 2596 471.6 2.2e-132
XP_011539698 (OMIM: 176262,616366) PREDICTED: pota ( 499) 2596 471.6 2.2e-132
NP_004965 (OMIM: 176262,616366) potassium voltage- ( 499) 2596 471.6 2.2e-132
XP_016856702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 2596 471.6 2.2e-132
XP_011539702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 2596 471.6 2.2e-132
XP_011539701 (OMIM: 176262,616366) PREDICTED: pota ( 499) 2596 471.6 2.2e-132
NP_002223 (OMIM: 176263) potassium voltage-gated c ( 575) 2315 421.9 2.3e-117
NP_005540 (OMIM: 602420) potassium voltage-gated c ( 511) 1951 357.4 5.6e-98
NP_001191198 (OMIM: 176262,616366) potassium volta ( 356) 1579 291.3 3.1e-78
NP_002224 (OMIM: 176266) potassium voltage-gated c ( 653) 1280 238.7 4e-62
XP_016874761 (OMIM: 176257) PREDICTED: potassium v ( 529) 1200 224.4 6.5e-58
XP_011519257 (OMIM: 176257) PREDICTED: potassium v ( 529) 1200 224.4 6.5e-58
XP_016874759 (OMIM: 176257) PREDICTED: potassium v ( 529) 1200 224.4 6.5e-58
NP_002226 (OMIM: 176257) potassium voltage-gated c ( 529) 1200 224.4 6.5e-58
XP_005253743 (OMIM: 176257) PREDICTED: potassium v ( 529) 1200 224.4 6.5e-58
XP_016874760 (OMIM: 176257) PREDICTED: potassium v ( 529) 1200 224.4 6.5e-58
NP_114092 (OMIM: 176268) potassium voltage-gated c ( 456) 1156 216.5 1.3e-55
NP_002225 (OMIM: 176267,612240) potassium voltage- ( 613) 928 176.3 2.3e-43
NP_004761 (OMIM: 607738) potassium voltage-gated c ( 911) 762 147.1 2.1e-34
XP_006723847 (OMIM: 600397,616056) PREDICTED: pota ( 858) 755 145.8 4.7e-34
NP_004966 (OMIM: 600397,616056) potassium voltage- ( 858) 755 145.8 4.7e-34
XP_011527101 (OMIM: 600397,616056) PREDICTED: pota ( 858) 755 145.8 4.7e-34
NP_002242 (OMIM: 602905) potassium voltage-gated c ( 526) 732 141.4 5.8e-33
NP_001309728 (OMIM: 602905) potassium voltage-gate ( 526) 732 141.4 5.8e-33
XP_016883335 (OMIM: 602905) PREDICTED: potassium v ( 527) 732 141.4 5.9e-33
NP_579875 (OMIM: 606767) potassium voltage-gated c ( 436) 685 133.0 1.7e-30
NP_758857 (OMIM: 607603) potassium voltage-gated c ( 519) 666 129.7 1.9e-29
NP_055194 (OMIM: 608164) potassium voltage-gated c ( 500) 661 128.8 3.5e-29
NP_001106212 (OMIM: 176258,616187) potassium volta ( 585) 659 128.6 4.9e-29
XP_016869470 (OMIM: 607738) PREDICTED: potassium v ( 666) 656 128.1 7.6e-29
XP_016869471 (OMIM: 607738) PREDICTED: potassium v ( 666) 656 128.1 7.6e-29
XP_011539703 (OMIM: 176265) PREDICTED: potassium v ( 609) 650 127.0 1.5e-28
XP_006710688 (OMIM: 176265) PREDICTED: potassium v ( 618) 650 127.0 1.5e-28
XP_006710690 (OMIM: 176265) PREDICTED: potassium v ( 624) 650 127.0 1.5e-28
NP_001034663 (OMIM: 176265) potassium voltage-gate ( 626) 650 127.0 1.5e-28
NP_004969 (OMIM: 176265) potassium voltage-gated c ( 635) 650 127.0 1.5e-28
NP_004970 (OMIM: 300281) potassium voltage-gated c ( 647) 648 126.7 2e-28
XP_011542212 (OMIM: 300281) PREDICTED: potassium v ( 647) 648 126.7 2e-28
NP_036413 (OMIM: 605410) potassium voltage-gated c ( 630) 647 126.5 2.2e-28
NP_715624 (OMIM: 176256) potassium voltage-gated c ( 558) 645 126.1 2.6e-28
XP_005268912 (OMIM: 176256) PREDICTED: potassium v ( 574) 645 126.1 2.7e-28
NP_001247428 (OMIM: 176256) potassium voltage-gate ( 583) 645 126.1 2.7e-28
XP_006719447 (OMIM: 176256) PREDICTED: potassium v ( 612) 645 126.1 2.8e-28
XP_006719446 (OMIM: 176256) PREDICTED: potassium v ( 612) 645 126.1 2.8e-28
XP_016874771 (OMIM: 176256) PREDICTED: potassium v ( 612) 645 126.1 2.8e-28
XP_006719448 (OMIM: 176256) PREDICTED: potassium v ( 612) 645 126.1 2.8e-28
XP_006719445 (OMIM: 176256) PREDICTED: potassium v ( 613) 645 126.1 2.8e-28
NP_631874 (OMIM: 176256) potassium voltage-gated c ( 613) 645 126.1 2.8e-28
>>NP_000208 (OMIM: 160120,176260) potassium voltage-gate (495 aa)
initn: 3258 init1: 3258 opt: 3258 Z-score: 3131.5 bits: 588.9 E(85289): 1.1e-167
Smith-Waterman score: 3258; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:1-495)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 IVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTT
430 440 450 460 470 480
490
pF1KB9 ANQNCVNKSKLLTDV
:::::::::::::::
NP_000 ANQNCVNKSKLLTDV
490
>>XP_011539699 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2497.6 bits: 471.6 E(85289): 2.2e-132
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
XP_011 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
XP_011 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
XP_011 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
XP_011 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
XP_011 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
XP_011 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
XP_011 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
XP_011 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
XP_011 LKTANCTLANTNYVNITKMLTDV
480 490
>>XP_011539700 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2497.6 bits: 471.6 E(85289): 2.2e-132
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
XP_011 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
XP_011 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
XP_011 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
XP_011 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
XP_011 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
XP_011 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
XP_011 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
XP_011 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
XP_011 LKTANCTLANTNYVNITKMLTDV
480 490
>>XP_011539698 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2497.6 bits: 471.6 E(85289): 2.2e-132
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
XP_011 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
XP_011 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
XP_011 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
XP_011 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
XP_011 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
XP_011 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
XP_011 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
XP_011 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
XP_011 LKTANCTLANTNYVNITKMLTDV
480 490
>>NP_004965 (OMIM: 176262,616366) potassium voltage-gate (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2497.6 bits: 471.6 E(85289): 2.2e-132
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
NP_004 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
NP_004 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
NP_004 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
NP_004 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
NP_004 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
NP_004 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
NP_004 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
NP_004 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
NP_004 LKTANCTLANTNYVNITKMLTDV
480 490
>>XP_016856702 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2497.6 bits: 471.6 E(85289): 2.2e-132
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
XP_016 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
XP_016 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
XP_016 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
XP_016 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
XP_016 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
XP_016 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
XP_016 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
XP_016 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
XP_016 LKTANCTLANTNYVNITKMLTDV
480 490
>>XP_011539702 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2497.6 bits: 471.6 E(85289): 2.2e-132
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
XP_011 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
XP_011 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
XP_011 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
XP_011 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
XP_011 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
XP_011 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
XP_011 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
XP_011 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
XP_011 LKTANCTLANTNYVNITKMLTDV
480 490
>>XP_011539701 (OMIM: 176262,616366) PREDICTED: potassiu (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2497.6 bits: 471.6 E(85289): 2.2e-132
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
XP_011 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
XP_011 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
XP_011 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
XP_011 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
XP_011 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
XP_011 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
XP_011 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
XP_011 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
XP_011 LKTANCTLANTNYVNITKMLTDV
480 490
>>NP_002223 (OMIM: 176263) potassium voltage-gated chann (575 aa)
initn: 2345 init1: 997 opt: 2315 Z-score: 2227.9 bits: 421.9 E(85289): 2.3e-117
Smith-Waterman score: 2367; 72.2% identity (85.2% similar) in 528 aa overlap (1-495:53-575)
10 20
pF1KB9 MTVMSGENVDEASAAPGH---PQDGS----
:::. :... : .: : :: :
NP_002 PQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGG
30 40 50 60 70 80
30 40 50 60 70
pF1KB9 ---Y----PRQADHDDHECC-ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDP
: : ...:: ::::::::::::::::::: :::.::::.::.:::::::
NP_002 CDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDP
90 100 110 120 130 140
80 90 100 110 120 130
pF1KB9 LRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEG
::::::::::::::::::::::::::.:::::::.:.:::::.::.::::::::::::::
NP_002 LRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEG
150 160 170 180 190 200
140 150 160 170 180 190
pF1KB9 FIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDD
:..:::::::....:::::::::::::::::: ::::::.::::::::::::::::..:.
NP_002 FLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE
210 220 230 240 250 260
200 210 220 230 240
pF1KB9 KDFTGTVHRIDNTTVIYNS--------NIFTDPFFIVETLCIIWFSFELVVRFFACPSKT
::. ... . :. . :: . :.::::.:::::::::::::.:::::::::.
NP_002 KDYPASTSQ-DSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKA
270 280 290 300 310 320
250 260 270 280 290 300
pF1KB9 DFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSR
: .::::.::::::::::::::::.::..:: :.:: :::::::::::::::::::::
NP_002 TFSRNIMNLIDIVAIIPYFITLGTELAERQGN--GQQAMSLAILRVIRLVRVFRIFKLSR
330 340 350 360 370
310 320 330 340 350 360
pF1KB9 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAV
::::::::::::::::::::::::::::::::::::::::::.. : ::::::::::::
NP_002 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAV
380 390 400 410 420 430
370 380 390 400 410 420
pF1KB9 VSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQL
:.:::::::::.:::::::::::::::::::::::::::::::::::::::::::::.:
NP_002 VTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQY
440 450 460 470 480 490
430 440 450 460 470
pF1KB9 LHVSS-PNLASDSDLSR--RSSSTMSKSEYMEIEED-MNNSIAHYRQVNIRTAN----CT
.::.: .:.:... : ::.::.:::::: ::: ::.: . :. ..:.: ::
NP_002 MHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSA--FPQTPFKTGNSTATCT
500 510 520 530 540 550
480 490
pF1KB9 TANQ--NCVNKSKLLTDV
: :. .::: .:..:::
NP_002 TNNNPNSCVNIKKIFTDV
560 570
>>NP_005540 (OMIM: 602420) potassium voltage-gated chann (511 aa)
initn: 1945 init1: 1592 opt: 1951 Z-score: 1880.0 bits: 357.4 E(85289): 5.6e-98
Smith-Waterman score: 1951; 69.5% identity (88.7% similar) in 416 aa overlap (13-427:64-476)
10 20 30 40
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVIN
: :: : :. . . : .::.::
NP_005 STSPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLN--EGNQRVIIN
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB9 ISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL
:.::::::::.::.:::.::::. .:::..:: .::::::::::::::.:::::::::..
NP_005 IAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKI
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB9 RRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPES
:::.:::.:.:..::.::::: :::..:::::::::. : :: .. .:: :::::::::
NP_005 RRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPES
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB9 SGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVH-RIDNTTVIYNSNIFTDPF
:. ::..:.:::.:..:::.:::::::::...:... . .. . .. ....:::::
NP_005 SSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPF
220 230 240 250 260 270
230 240 250 260 270 280
pF1KB9 FIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQK
:.::. ::.::.::::.:: .::::::::.::::.:::..::::: :: ::.. :: . .
NP_005 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELV-QETEPS
280 290 300 310 320 330
290 300 310 320 330 340
pF1KB9 GEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS
..: ::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS
340 350 360 370 380 390
350 360 370 380 390 400
pF1KB9 SAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIA
:::::::..: :::::::::.::::::.::::::::: :.: ::::::.:::::::::::
NP_005 SAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIA
400 410 420 430 440 450
410 420 430 440 450 460
pF1KB9 LPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDM
:::::::::::::::::::.::. ..
NP_005 LPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKSR
460 470 480 490 500 510
495 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:55:21 2016 done: Fri Nov 4 19:55:23 2016
Total Scan time: 9.320 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]