Result of FASTA (ccds) for
pF1KB9872
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9872, 495 aa
1>>>pF1KB9872 495 - 495 aa - 495 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0539+/-0.00103; mu= 19.7885+/- 0.062
mean_var=77.3389+/-15.484, 0's: 0 Z-trim(104.5): 139 B-trim: 31 in 1/49
Lambda= 0.145840
statistics sampled from 7775 (7935) to 7775 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.244), width: 16
Scan time: 2.770
The best scores are: opt bits E(32554)
CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 ( 495) 3258 695.5 3.4e-200
CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 ( 499) 2596 556.2 2.9e-158
CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 ( 575) 2315 497.1 2e-140
CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 ( 511) 1951 420.5 2.1e-117
CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 ( 356) 1579 342.1 5.9e-94
CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 ( 653) 1280 279.4 8e-75
CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 ( 529) 1200 262.5 8e-70
CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 ( 456) 1156 253.2 4.4e-67
CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 ( 613) 928 205.3 1.5e-52
CCDS6209.1 KCNB2 gene_id:9312|Hs108|chr8 ( 911) 762 170.6 6.6e-42
CCDS13418.1 KCNB1 gene_id:3745|Hs108|chr20 ( 858) 755 169.1 1.8e-41
CCDS13342.1 KCNS1 gene_id:3787|Hs108|chr20 ( 526) 732 164.0 3.5e-40
CCDS1809.1 KCNG3 gene_id:170850|Hs108|chr2 ( 436) 685 154.1 2.9e-37
CCDS10945.1 KCNG4 gene_id:93107|Hs108|chr16 ( 519) 666 150.2 5.3e-36
CCDS6314.1 KCNV1 gene_id:27012|Hs108|chr8 ( 500) 661 149.1 1.1e-35
CCDS44547.1 KCNC1 gene_id:3746|Hs108|chr11 ( 585) 659 148.7 1.6e-35
CCDS44193.1 KCNC4 gene_id:3749|Hs108|chr1 ( 626) 650 146.9 6.2e-35
CCDS821.1 KCNC4 gene_id:3749|Hs108|chr1 ( 635) 650 146.9 6.3e-35
CCDS14314.1 KCND1 gene_id:3750|Hs108|chrX ( 647) 648 146.5 8.5e-35
CCDS5776.1 KCND2 gene_id:3751|Hs108|chr7 ( 630) 647 146.2 9.7e-35
CCDS9006.1 KCNC2 gene_id:3747|Hs108|chr12 ( 558) 645 145.8 1.2e-34
CCDS58255.1 KCNC2 gene_id:3747|Hs108|chr12 ( 583) 645 145.8 1.2e-34
CCDS9005.1 KCNC2 gene_id:3747|Hs108|chr12 ( 613) 645 145.8 1.3e-34
CCDS58257.1 KCNC2 gene_id:3747|Hs108|chr12 ( 618) 645 145.8 1.3e-34
CCDS58256.1 KCNC2 gene_id:3747|Hs108|chr12 ( 629) 645 145.8 1.3e-34
CCDS9007.1 KCNC2 gene_id:3747|Hs108|chr12 ( 638) 645 145.8 1.3e-34
CCDS7827.1 KCNC1 gene_id:3746|Hs108|chr11 ( 511) 636 143.8 4.1e-34
CCDS844.1 KCND3 gene_id:3752|Hs108|chr1 ( 636) 636 143.9 4.9e-34
CCDS843.1 KCND3 gene_id:3752|Hs108|chr1 ( 655) 636 143.9 5e-34
CCDS1692.1 KCNS3 gene_id:3790|Hs108|chr2 ( 491) 626 141.7 1.7e-33
CCDS6279.1 KCNS2 gene_id:3788|Hs108|chr8 ( 477) 616 139.6 7.3e-33
CCDS1676.1 KCNF1 gene_id:3754|Hs108|chr2 ( 494) 612 138.8 1.3e-32
CCDS12793.1 KCNC3 gene_id:3748|Hs108|chr19 ( 757) 610 138.5 2.4e-32
CCDS6447.1 KCNV2 gene_id:169522|Hs108|chr9 ( 545) 606 137.6 3.4e-32
CCDS12019.1 KCNG2 gene_id:26251|Hs108|chr18 ( 466) 582 132.4 1e-30
CCDS13436.1 KCNG1 gene_id:3755|Hs108|chr20 ( 513) 570 130.0 6.3e-30
CCDS42674.1 KCNG3 gene_id:170850|Hs108|chr2 ( 425) 565 128.8 1.1e-29
CCDS13521.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 393) 327 78.7 1.3e-14
CCDS46629.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 841) 327 79.0 2.2e-14
CCDS13518.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 844) 327 79.0 2.2e-14
CCDS13519.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 854) 327 79.0 2.2e-14
CCDS13520.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 872) 327 79.0 2.3e-14
CCDS7736.1 KCNQ1 gene_id:3784|Hs108|chr11 ( 676) 312 75.8 1.7e-13
CCDS456.1 KCNQ4 gene_id:9132|Hs108|chr1 ( 695) 307 74.7 3.6e-13
CCDS55034.1 KCNQ5 gene_id:56479|Hs108|chr6 ( 951) 307 74.9 4.5e-13
CCDS55035.1 KCNQ5 gene_id:56479|Hs108|chr6 ( 822) 302 73.7 8.4e-13
CCDS55037.1 KCNQ5 gene_id:56479|Hs108|chr6 ( 923) 302 73.8 9.1e-13
CCDS4976.1 KCNQ5 gene_id:56479|Hs108|chr6 ( 932) 302 73.8 9.2e-13
>>CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 (495 aa)
initn: 3258 init1: 3258 opt: 3258 Z-score: 3707.5 bits: 695.5 E(32554): 3.4e-200
Smith-Waterman score: 3258; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:1-495)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 IVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 IVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 FACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 FACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 RIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 DAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 GEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTT
430 440 450 460 470 480
490
pF1KB9 ANQNCVNKSKLLTDV
:::::::::::::::
CCDS85 ANQNCVNKSKLLTDV
490
>>CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 (499 aa)
initn: 2528 init1: 1034 opt: 2596 Z-score: 2954.7 bits: 556.2 E(32554): 2.9e-158
Smith-Waterman score: 2596; 80.3% identity (90.9% similar) in 503 aa overlap (1-495:1-499)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
CCDS82 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
CCDS82 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
CCDS82 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
CCDS82 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
CCDS82 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
CCDS82 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERES
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB9 HFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
.: ::::::::::::::::::::: :.:::::::::::::::::::::::::::::::::
CCDS82 QFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB9 YHRETEGEEQAQLLHVSS-PNLASDSDLSR-RSSSTMSKSEYMEIEEDMNNSIAHYRQVN
:::::::::::: :.:.: :.. :. ::.. ::.::.:::.::::.: .::: .:. :
CCDS82 YHRETEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREEN
420 430 440 450 460 470
480 490
pF1KB9 IRTANCTTANQNCVNKSKLLTDV
..::::: :: : :: .:.::::
CCDS82 LKTANCTLANTNYVNITKMLTDV
480 490
>>CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 (575 aa)
initn: 2345 init1: 997 opt: 2315 Z-score: 2634.4 bits: 497.1 E(32554): 2e-140
Smith-Waterman score: 2367; 72.2% identity (85.2% similar) in 528 aa overlap (1-495:53-575)
10 20
pF1KB9 MTVMSGENVDEASAAPGH---PQDGS----
:::. :... : .: : :: :
CCDS82 PQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGG
30 40 50 60 70 80
30 40 50 60 70
pF1KB9 ---Y----PRQADHDDHECC-ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDP
: : ...:: ::::::::::::::::::: :::.::::.::.:::::::
CCDS82 CDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDP
90 100 110 120 130 140
80 90 100 110 120 130
pF1KB9 LRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEG
::::::::::::::::::::::::::.:::::::.:.:::::.::.::::::::::::::
CCDS82 LRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEG
150 160 170 180 190 200
140 150 160 170 180 190
pF1KB9 FIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDD
:..:::::::....:::::::::::::::::: ::::::.::::::::::::::::..:.
CCDS82 FLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE
210 220 230 240 250 260
200 210 220 230 240
pF1KB9 KDFTGTVHRIDNTTVIYNS--------NIFTDPFFIVETLCIIWFSFELVVRFFACPSKT
::. ... . :. . :: . :.::::.:::::::::::::.:::::::::.
CCDS82 KDYPASTSQ-DSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKA
270 280 290 300 310 320
250 260 270 280 290 300
pF1KB9 DFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSR
: .::::.::::::::::::::::.::..:: :.:: :::::::::::::::::::::
CCDS82 TFSRNIMNLIDIVAIIPYFITLGTELAERQGN--GQQAMSLAILRVIRLVRVFRIFKLSR
330 340 350 360 370
310 320 330 340 350 360
pF1KB9 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAV
::::::::::::::::::::::::::::::::::::::::::.. : ::::::::::::
CCDS82 HSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAV
380 390 400 410 420 430
370 380 390 400 410 420
pF1KB9 VSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQL
:.:::::::::.:::::::::::::::::::::::::::::::::::::::::::::.:
CCDS82 VTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQY
440 450 460 470 480 490
430 440 450 460 470
pF1KB9 LHVSS-PNLASDSDLSR--RSSSTMSKSEYMEIEED-MNNSIAHYRQVNIRTAN----CT
.::.: .:.:... : ::.::.:::::: ::: ::.: . :. ..:.: ::
CCDS82 MHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSA--FPQTPFKTGNSTATCT
500 510 520 530 540 550
480 490
pF1KB9 TANQ--NCVNKSKLLTDV
: :. .::: .:..:::
CCDS82 TNNNPNSCVNIKKIFTDV
560 570
>>CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 (511 aa)
initn: 1945 init1: 1592 opt: 1951 Z-score: 2221.2 bits: 420.5 E(32554): 2.1e-117
Smith-Waterman score: 1951; 69.5% identity (88.7% similar) in 416 aa overlap (13-427:64-476)
10 20 30 40
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVIN
: :: : :. . . : .::.::
CCDS82 STSPKGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLN--EGNQRVIIN
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB9 ISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRL
:.::::::::.::.:::.::::. .:::..:: .::::::::::::::.:::::::::..
CCDS82 IAGLRFETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKI
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB9 RRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPES
:::.:::.:.:..::.::::: :::..:::::::::. : :: .. .:: :::::::::
CCDS82 RRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFWLLFEYPES
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB9 SGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVH-RIDNTTVIYNSNIFTDPF
:. ::..:.:::.:..:::.:::::::::...:... . .. . .. ....:::::
CCDS82 SSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPNLNMSKTVLSQTMFTDPF
220 230 240 250 260 270
230 240 250 260 270 280
pF1KB9 FIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQK
:.::. ::.::.::::.:: .::::::::.::::.:::..::::: :: ::.. :: . .
CCDS82 FMVESTCIVWFTFELVLRFVVCPSKTDFFRNIMNIIDIISIIPYFATLITELV-QETEPS
280 290 300 310 320 330
290 300 310 320 330 340
pF1KB9 GEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS
..: ::::::.::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 AQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFS
340 350 360 370 380 390
350 360 370 380 390 400
pF1KB9 SAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIA
:::::::..: :::::::::.::::::.::::::::: :.: ::::::.:::::::::::
CCDS82 SAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIA
400 410 420 430 440 450
410 420 430 440 450 460
pF1KB9 LPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDM
:::::::::::::::::::.::. ..
CCDS82 LPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKSR
460 470 480 490 500 510
>>CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 (356 aa)
initn: 1523 init1: 1034 opt: 1579 Z-score: 1800.2 bits: 342.1 E(32554): 5.9e-94
Smith-Waterman score: 1579; 75.9% identity (88.3% similar) in 324 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPN
::: .:. .:::.: :::::: .: .::: ::::::::::::::::::::::::::.
CCDS55 MTVATGDPADEAAALPGHPQD-TYDPEADH---ECCERVVINISGLRFETQLKTLAQFPE
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY
::::.::::::::::::::::::::::::::::::::::::::::::::::.:::::.::
CCDS55 TLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILIS
:::::::: ::::::.::::::::::.:.::::::::::::::::::.::::::::::::
CCDS55 ELGEEAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILIS
120 130 140 150 160 170
190 200 210 220 230
pF1KB9 IVIFCLETLPELKDD-KDFTG---TVHRIDNTTVIYN-SNIFTDPFFIVETLCIIWFSFE
:: ::::::: ..:. .:. : : : .:.:. :. :. :::::::::::::::::::
CCDS55 IVSFCLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQ-EGNQKGEQATSLAILRVI
..:::::::::. :: ::::.::::::::::::::::.::. : :.:.:: ::::::::
CCDS55 FLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 RLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAES
:: : : .. .. ..: : :. .
CCDS55 RLER--RPLQSQKSKRGRQHLNTSHDCTLGINLVAGMTVQWTRASGPDDRQTPAVTTLHR
300 310 320 330 340 350
>>CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 (653 aa)
initn: 1874 init1: 859 opt: 1280 Z-score: 1456.8 bits: 279.4 E(32554): 8e-75
Smith-Waterman score: 2217; 68.7% identity (85.4% similar) in 508 aa overlap (10-495:149-653)
10 20 30
pF1KB9 MTVMSGENVDEASAAPGHPQD---GSYPRQADHDDHECC
:: : . ::: :.: : ::
CCDS41 RELSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYSD---CC
120 130 140 150 160 170
40 50 60 70 80 90
pF1KB9 ERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYY
::::::.::::::::.:::::::.::::.:.:: .:::::::::::::::::::::::::
CCDS41 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY
180 190 200 210 220 230
100 110 120 130 140 150
pF1KB9 QSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEE-RPLPEKEYQRQVWL
::::::.::::::.:.:.::.:::.:::::. ::::::::..::: : :::.:...:.::
CCDS41 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWL
240 250 260 270 280 290
160 170 180 190 200
pF1KB9 LFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFT------GTVHRIDNTT
::::::::.::: ::::::.::::::::::::::::..::.:.. : ...:.
CCDS41 LFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTS
300 310 320 330 340 350
210 220 230 240 250 260
pF1KB9 V--IYNSN--IFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPY
. . ::. ::.::::::::.::.:::::.::: :::::.. :::::::.::::.:.::
CCDS41 APHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPY
360 370 380 390 400 410
270 280 290 300 310 320
pF1KB9 FITLGTEIAEQEGNQKGEQ--ATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASM
::::::..:.:.:. .:.: : :.::::.:::::::::::::::::::::::.::.:::
CCDS41 FITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASM
420 430 440 450 460 470
330 340 350 360 370 380
pF1KB9 RELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTI
::::::::::::::::::::::::::.: .::.:::::::::::.::::::::: :.:.
CCDS41 RELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITV
480 490 500 510 520 530
390 400 410 420 430 440
pF1KB9 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLH--VSSPNLASDSDL
:::::::::::::::::::::::::::::::::::::.:::.:: . :: : : :.
CCDS41 GGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAVSCPYLPSNLLK
540 550 560 570 580 590
450 460 470 480 490
pF1KB9 SRRSSSTMS---KSEYMEIEEDMNNSI-AHYRQVNIRTANCTTANQNCVNKSKLLTDV
. :::.. : ::::.:.:: ...:. :. .. . . . : ..:: : . . :::
CCDS41 KFRSSTSSSLGDKSEYLEMEEGVKESLCAKEEKCQGKGDDSETDKNNCSNAKAVETDV
600 610 620 630 640 650
>>CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 (529 aa)
initn: 2044 init1: 851 opt: 1200 Z-score: 1367.0 bits: 262.5 E(32554): 8e-70
Smith-Waterman score: 2012; 66.9% identity (81.3% similar) in 481 aa overlap (17-443:20-498)
10 20 30 40 50
pF1KB9 MTVMSGENVDEASAAPGHPQD-GSYPRQADHDDHECC--ERVVINISGLRFETQLKT
:. :: :..:. . :: ::.:::::::::::::.:
CCDS85 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGG--CCSSERLVINISGLRFETQLRT
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 LAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFS
:. ::.::::.: .:.:.:::::::::::::::::::::::::::::::::::::::.:
CCDS85 LSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 EEIKFYELGEEAMEKFREDEGFIKE---EERPLPEKEYQRQVWLLFEYPESSGPARVIAI
:::.::.::.::. :::::: . : .:.::: . .:::::::::::::::::: :::
CCDS85 EEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAI
120 130 140 150 160 170
180 190 200 210
pF1KB9 VSVMVILISIVIFCLETLPELKDDK--DFTGTVHRI--------------DNTTVIYNS-
:::.:::::::::::::::... : .: : :. :.. .....
CCDS85 VSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGI
180 190 200 210 220 230
220 230 240 250
pF1KB9 ------------------NIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNF
..::::::.::::::.::.:::.::: ::::: ::.::::.
CCDS85 TPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNI
240 250 260 270 280 290
260 270 280 290 300
pF1KB9 IDIVAIIPYFITLGTEIAEQE--------GNQKGEQATSLAILRVIRLVRVFRIFKLSRH
::.:::.:::::::::...:. :.:.:.:: ::::::::::::::::::::::
CCDS85 IDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRH
300 310 320 330 340 350
310 320 330 340 350 360
pF1KB9 SKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVV
::::::::.::.:::::::::::::::::::::::::::::.. .: : :::::::::::
CCDS85 SKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVV
360 370 380 390 400 410
370 380 390 400 410 420
pF1KB9 SMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLL
.:::::::::::.:.::::::::::::::::::::::::::::::::::::: :::.:
CCDS85 TMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYT
420 430 440 450 460 470
430 440 450 460 470 480
pF1KB9 HVS----SPNL-ASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTTANQ
::. .:.: :.:. :..
CCDS85 HVTCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV
480 490 500 510 520
>>CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 (456 aa)
initn: 1941 init1: 844 opt: 1156 Z-score: 1317.8 bits: 253.2 E(32554): 4.4e-67
Smith-Waterman score: 1904; 68.9% identity (87.0% similar) in 408 aa overlap (35-430:11-416)
10 20 30 40 50 60
pF1KB9 SGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLG
::::.:.:..::::::. .::..::.::::
CCDS12 MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLG
10 20 30 40
70 80 90 100 110 120
pF1KB9 NPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGE
.: .: :..: : ::::::.::::::.:::::::::::::..::::.: ::. :: ::
CCDS12 DPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 EAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIF
:. ..::::: :::::.. . ::.:::::.:::: :::.:.:::.:::.:::.:
CCDS12 AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVF
110 120 130 140 150 160
190 200 210 220 230
pF1KB9 CLETLPELKDDKDFTGTVHRID--------NTTVIYNSNI----FTDPFFIVETLCIIWF
::::::...::.: :: . : . . .: :.::::.:::::: ::
CCDS12 CLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRLPFNDPFFVVETLCICWF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB9 SFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILR
::::.::...::::. ::::.::.::.:::.:::..::::.:.:.: :.:: ::::::
CCDS12 SFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELARQRGV--GQQAMSLAILR
230 240 250 260 270
300 310 320 330 340 350
pF1KB9 VIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEA
:::::::::::::::::::::::::::.:::::::::::::::::.::::::::::....
CCDS12 VIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 ESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFN
.:::.:::..::::::.::::::::: :::.:::::::::::::::::.::::::::::.
CCDS12 DSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFS
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB9 YFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVN
::::::::::: ... ::
CCDS12 YFYHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGKHLVTEV
400 410 420 430 440 450
>>CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 (613 aa)
initn: 2056 init1: 918 opt: 928 Z-score: 1056.9 bits: 205.3 E(32554): 1.5e-52
Smith-Waterman score: 2042; 69.5% identity (83.3% similar) in 462 aa overlap (17-448:100-559)
10 20 30 40
pF1KB9 MTVMSGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGL
: : :. :: .:: ::::::
CCDS85 LPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQRVHINISGL
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB9 RFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPV
:::::: :::::::::::.: ::.::::::::::::::::::::.:::::::::::::::
CCDS85 RFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPV
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB9 NVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPA
:: ::.:..::.::.::.::::.::::::::::::.:::..:.::::::.:::::::: :
CCDS85 NVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIFEYPESSGSA
190 200 210 220 230 240
170 180 190 200
pF1KB9 RVIAIVSVMVILISIVIFCLETLPELKDDKDF-------------------TGTVHRIDN
:.::::::.::::::. ::::::::..:.... .:.. ..
CCDS85 RAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANGSGVMAPPSG
250 260 270 280 290 300
210 220 230 240 250 260
pF1KB9 TTVI-YNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYF
:: ..:::::::: :.:::.:::.:::::::::. : .::::.::.:::.:::
CCDS85 PTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNIIDVVAIFPYF
310 320 330 340 350 360
270 280 290 300 310 320
pF1KB9 ITLGTEIAEQE-----GNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKA
::::::.:::. :.:.:.:: ::::::::::::::::::::::::::::::.::.:
CCDS85 ITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQA
370 380 390 400 410 420
330 340 350 360 370 380
pF1KB9 SMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPV
::::::::::::::::::::::::::::.. .::::::::::::::.::::::::: :.
CCDS85 SMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPI
430 440 450 460 470 480
390 400 410 420 430
pF1KB9 TIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQA-----QLLHVSSPNLA
:.::::::::::::::::::::::::::::::::::::. :: : : . ..:.:
CCDS85 TVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGL-
490 500 510 520 530 540
440 450 460 470 480 490
pF1KB9 SDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTTANQNCVNKSKLLTDV
: ..:. :..
CCDS85 -DRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSLYALCLDT
550 560 570 580 590 600
>>CCDS6209.1 KCNB2 gene_id:9312|Hs108|chr8 (911 aa)
initn: 963 init1: 519 opt: 762 Z-score: 865.8 bits: 170.6 E(32554): 6.6e-42
Smith-Waterman score: 930; 39.4% identity (68.2% similar) in 421 aa overlap (35-425:33-433)
10 20 30 40 50 60
pF1KB9 SGENVDEASAAPGHPQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLG
: .:: ::..:: :. .:: ..: : ::
CCDS62 EKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLG
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 -----NPKKRM-RYFDPL---RNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSE
: .. . . : .:::::::. .: .:: .:..: .:. .. :..
CCDS62 KLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTG-KLHMMEEMCALSFGQ
70 80 90 100 110 120
120 130 140 150
pF1KB9 EIKFYELGEEAME-----KFREDEGFIKEEER----PLPEKEYQ-----------RQVWL
:. .. . : .: .... . ..:: : . :.: . ...:
CCDS62 ELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLWD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 LFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSN
:.: :.:: :...::::.. :..: . . :.:::::.. .: : .. :: . .
CCDS62 LLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEF-GQLN--DNRQLAH---
190 200 210 220 230
220 230 240 250 260 270
pF1KB9 IFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE
::..:: ::..: ..::.. :.: :::. .: ::..::.::..: :
CCDS62 --------VEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVT----IFL
240 250 260 270 280
280 290 300 310 320 330
pF1KB9 QEGNQKGEQATSLA-ILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF
:.:.. : .. .....:..:..::.::.::: ::: :: ::. :. ::::::.::
CCDS62 TESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLA
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB9 IGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAI
.:...::: :.::: .: ..:.::: .::::...::::::::.:: :. :::::.:: :
CCDS62 MGIMIFSSLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCI
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB9 AGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASDSDLSRRSSSTMSKSEY
::::.::::.:.::.::. :: .: . .:.:
CCDS62 AGVLVIALPIPIIVNNFSEFY-KEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSM
410 420 430 440 450 460
460 470 480 490
pF1KB9 MEIEEDMNNSIAHYRQVNIRTANCTTANQNCVNKSKLLTDV
CCDS62 ELIDVAVEKAGESANTKDSADDNHLSPSRWKWARKALSETSSNKSFENKYQEVSQKDSHE
470 480 490 500 510 520
495 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:55:21 2016 done: Fri Nov 4 19:55:21 2016
Total Scan time: 2.770 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]