Result of FASTA (omim) for
pF1KB9851
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9851, 380 aa
1>>>pF1KB9851 380 - 380 aa - 380 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2311+/-0.000343; mu= 18.9973+/- 0.022
mean_var=86.1710+/-16.880, 0's: 0 Z-trim(115.4): 19 B-trim: 22 in 1/53
Lambda= 0.138164
statistics sampled from 25805 (25824) to 25805 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.303), width: 16
Scan time: 6.910
The best scores are: opt bits E(85289)
NP_004102 (OMIM: 600393) flap endonuclease 1 [Homo ( 380) 2484 504.8 1.3e-142
NP_003677 (OMIM: 606063) exonuclease 1 isoform a [ ( 803) 371 84.0 1.4e-15
NP_001306153 (OMIM: 606063) exonuclease 1 isoform ( 845) 371 84.0 1.4e-15
XP_011542625 (OMIM: 606063) PREDICTED: exonuclease ( 845) 371 84.0 1.4e-15
XP_011542624 (OMIM: 606063) PREDICTED: exonuclease ( 846) 371 84.0 1.4e-15
XP_011542623 (OMIM: 606063) PREDICTED: exonuclease ( 846) 371 84.0 1.4e-15
NP_569082 (OMIM: 606063) exonuclease 1 isoform b [ ( 846) 371 84.0 1.4e-15
XP_006711903 (OMIM: 606063) PREDICTED: exonuclease ( 846) 371 84.0 1.4e-15
NP_006018 (OMIM: 606063) exonuclease 1 isoform b [ ( 846) 371 84.0 1.4e-15
NP_001123481 (OMIM: 612449) flap endonuclease GEN ( 908) 255 60.9 1.4e-08
XP_011531124 (OMIM: 612449) PREDICTED: flap endonu ( 908) 255 60.9 1.4e-08
XP_011531122 (OMIM: 612449) PREDICTED: flap endonu ( 908) 255 60.9 1.4e-08
NP_872431 (OMIM: 612449) flap endonuclease GEN hom ( 908) 255 60.9 1.4e-08
XP_005262670 (OMIM: 612449) PREDICTED: flap endonu ( 908) 255 60.9 1.4e-08
XP_006712068 (OMIM: 612449) PREDICTED: flap endonu ( 908) 255 60.9 1.4e-08
XP_011531123 (OMIM: 612449) PREDICTED: flap endonu ( 908) 255 60.9 1.4e-08
XP_016858282 (OMIM: 606063) PREDICTED: exonuclease ( 806) 245 58.9 5e-08
XP_011542626 (OMIM: 606063) PREDICTED: exonuclease ( 806) 245 58.9 5e-08
NP_000114 (OMIM: 133530,278780,616570) DNA repair (1186) 242 58.4 1e-07
>>NP_004102 (OMIM: 600393) flap endonuclease 1 [Homo sap (380 aa)
initn: 2484 init1: 2484 opt: 2484 Z-score: 2681.3 bits: 504.8 E(85289): 1.3e-142
Smith-Waterman score: 2484; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 QEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 IGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEP
310 320 330 340 350 360
370 380
pF1KB9 KGSTKKKAKTGAAGKFKRGK
::::::::::::::::::::
NP_004 KGSTKKKAKTGAAGKFKRGK
370 380
>>NP_003677 (OMIM: 606063) exonuclease 1 isoform a [Homo (803 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.8 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
NP_003 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
NP_003 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
NP_003 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
NP_003 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
NP_003 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
NP_003 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>NP_001306153 (OMIM: 606063) exonuclease 1 isoform c [H (845 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.5 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
NP_001 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
NP_001 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
NP_001 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
NP_001 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
NP_001 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
NP_001 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>XP_011542625 (OMIM: 606063) PREDICTED: exonuclease 1 i (845 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.5 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
XP_011 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
XP_011 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
XP_011 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
XP_011 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
XP_011 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
XP_011 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>XP_011542624 (OMIM: 606063) PREDICTED: exonuclease 1 i (846 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.5 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
XP_011 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
XP_011 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
XP_011 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
XP_011 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
XP_011 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
XP_011 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>XP_011542623 (OMIM: 606063) PREDICTED: exonuclease 1 i (846 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.5 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
XP_011 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
XP_011 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
XP_011 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
XP_011 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
XP_011 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
XP_011 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>NP_569082 (OMIM: 606063) exonuclease 1 isoform b [Homo (846 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.5 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
NP_569 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
NP_569 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
NP_569 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
NP_569 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
NP_569 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
NP_569 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>XP_006711903 (OMIM: 606063) PREDICTED: exonuclease 1 i (846 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.5 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
XP_006 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
XP_006 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
XP_006 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
XP_006 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
XP_006 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
XP_006 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>NP_006018 (OMIM: 606063) exonuclease 1 isoform b [Homo (846 aa)
initn: 255 init1: 221 opt: 371 Z-score: 400.5 bits: 84.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 29.6% identity (59.1% similar) in 301 aa overlap (1-291:1-290)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
:::::: ..: . : . ...: :. ::.:. ... :: . . .::
NP_006 MGIQGLLQFIKE----ASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG
:.. .:. .. . :. .::::. :::: :. : : ..: .:.:. : : . .
NP_006 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE
. . : :: : ...:. . . .:. : :: ::.:. : : ::: : : ::
NP_006 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES
: : :.:: . :... ... .. .. . : : .. ...:.: .::: : :: :
NP_006 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD
.:::: .: ... .. .: ...... . :::.... .:.. :: :.:
NP_006 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB9 PESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL
:
NP_006 PIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPA
290 300 310 320 330 340
>>NP_001123481 (OMIM: 612449) flap endonuclease GEN homo (908 aa)
initn: 323 init1: 152 opt: 255 Z-score: 275.2 bits: 60.9 E(85289): 1.4e-08
Smith-Waterman score: 360; 27.5% identity (62.3% similar) in 265 aa overlap (1-264:1-239)
10 20 30 40 50 60
pF1KB9 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
::.. : ... : .. ... :. .:.: :. . . . .. :.:..
NP_001 MGVNDLWQILEPVK----QHIPLRNLGGKTIAVDLSLWVCEAQTVKKMMGSVMK------
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAE
:: ..:.: . . .: :.:..:.::.::. ..::.. : . . . .: .:
NP_001 -PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGK-SWSQKTG--
60 70 80 90 100
130 140 150 160 170 180
pF1KB9 QEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM
.. : ... :: :.: .:::...: .:::: :: : .:.: . :.:
NP_001 ---RSHFKSVLR-------ECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDG
110 120 130 140 150
190 200 210 220 230
pF1KB9 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYC-ESIR
: . .:. ...:..: . .: .. . .: : ..:::... .: : :::: :: ...
NP_001 DTFLYGAQTVYRNFTMN-TKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVP
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 GIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWS
:.: ..:. ::: :. . ...:..
NP_001 GVGKEQALKLIQILKG-QSLLQRFNRWNETSCNSSPQLLVTKKLAHCSVCSHPGSPKDHE
220 230 240 250 260 270
380 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:46:16 2016 done: Fri Nov 4 19:46:17 2016
Total Scan time: 6.910 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]