Result of FASTA (omim) for
pF1KB9779
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9779, 887 aa
1>>>pF1KB9779 887 - 887 aa - 887 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7279+/-0.000369; mu= 19.9140+/- 0.023
mean_var=89.5801+/-17.781, 0's: 0 Z-trim(114.6): 112 B-trim: 0 in 0/54
Lambda= 0.135509
statistics sampled from 24399 (24513) to 24399 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.287), width: 16
Scan time: 9.070
The best scores are: opt bits E(85289)
NP_002638 (OMIM: 602609) phosphatidylinositol 3-ki ( 887) 5897 1163.6 0
NP_001294949 (OMIM: 602609) phosphatidylinositol 3 ( 824) 5319 1050.6 0
XP_011524333 (OMIM: 602609) PREDICTED: phosphatidy ( 701) 4622 914.2 0
XP_016874968 (OMIM: 609001) PREDICTED: phosphatidy ( 817) 612 130.3 3.6e-29
NP_001275703 (OMIM: 609001) phosphatidylinositol 4 (1264) 612 130.5 5e-29
XP_016874966 (OMIM: 609001) PREDICTED: phosphatidy (1270) 612 130.5 5e-29
XP_016874965 (OMIM: 609001) PREDICTED: phosphatidy (1407) 612 130.5 5.5e-29
XP_016874964 (OMIM: 609001) PREDICTED: phosphatidy (1437) 612 130.5 5.6e-29
XP_011518999 (OMIM: 609001) PREDICTED: phosphatidy (1442) 612 130.5 5.6e-29
NP_004561 (OMIM: 609001) phosphatidylinositol 4-ph (1445) 612 130.5 5.6e-29
XP_016874963 (OMIM: 609001) PREDICTED: phosphatidy (1451) 612 130.5 5.6e-29
XP_011518998 (OMIM: 609001) PREDICTED: phosphatidy (1475) 612 130.5 5.7e-29
NP_001275701 (OMIM: 609001) phosphatidylinositol 4 (1486) 612 130.5 5.7e-29
XP_016874960 (OMIM: 609001) PREDICTED: phosphatidy (1492) 612 130.5 5.7e-29
XP_016874959 (OMIM: 609001) PREDICTED: phosphatidy (1492) 612 130.5 5.7e-29
XP_016874962 (OMIM: 609001) PREDICTED: phosphatidy (1492) 612 130.5 5.7e-29
XP_016874961 (OMIM: 609001) PREDICTED: phosphatidy (1492) 612 130.5 5.7e-29
NP_001269356 (OMIM: 601232) phosphatidylinositol 4 (1102) 576 123.4 5.9e-27
NP_001269355 (OMIM: 601232) phosphatidylinositol 4 (1102) 576 123.4 5.9e-27
NP_002640 (OMIM: 601232) phosphatidylinositol 4,5- (1102) 576 123.4 5.9e-27
XP_005250500 (OMIM: 601232) PREDICTED: phosphatidy (1102) 576 123.4 5.9e-27
XP_016856974 (OMIM: 602839,615513) PREDICTED: phos (1015) 567 121.6 1.9e-26
XP_016856973 (OMIM: 602839,615513) PREDICTED: phos (1043) 567 121.6 1.9e-26
XP_006710752 (OMIM: 602839,615513) PREDICTED: phos (1044) 567 121.6 1.9e-26
NP_005017 (OMIM: 602839,615513) phosphatidylinosit (1044) 567 121.6 1.9e-26
XP_006710750 (OMIM: 602839,615513) PREDICTED: phos (1044) 567 121.6 1.9e-26
XP_016856972 (OMIM: 602839,615513) PREDICTED: phos (1074) 567 121.6 2e-26
XP_016856966 (OMIM: 602839,615513) PREDICTED: phos (1103) 567 121.6 2e-26
XP_016856967 (OMIM: 602839,615513) PREDICTED: phos (1103) 567 121.6 2e-26
XP_016856970 (OMIM: 602839,615513) PREDICTED: phos (1103) 567 121.6 2e-26
XP_016856965 (OMIM: 602839,615513) PREDICTED: phos (1103) 567 121.6 2e-26
XP_016856971 (OMIM: 602839,615513) PREDICTED: phos (1103) 567 121.6 2e-26
XP_016856968 (OMIM: 602839,615513) PREDICTED: phos (1103) 567 121.6 2e-26
XP_016856969 (OMIM: 602839,615513) PREDICTED: phos (1103) 567 121.6 2e-26
NP_001242974 (OMIM: 602925) phosphatidylinositol 4 ( 582) 563 120.7 2.1e-26
XP_016862110 (OMIM: 602925) PREDICTED: phosphatidy ( 657) 563 120.7 2.3e-26
XP_016862109 (OMIM: 602925) PREDICTED: phosphatidy ( 674) 563 120.7 2.4e-26
XP_011511198 (OMIM: 602925) PREDICTED: phosphatidy ( 902) 563 120.8 3e-26
XP_016862108 (OMIM: 602925) PREDICTED: phosphatidy (1070) 563 120.8 3.4e-26
XP_005247587 (OMIM: 602925) PREDICTED: phosphatidy (1070) 563 120.8 3.4e-26
XP_011511197 (OMIM: 602925) PREDICTED: phosphatidy (1070) 563 120.8 3.4e-26
XP_006713722 (OMIM: 602925) PREDICTED: phosphatidy (1070) 563 120.8 3.4e-26
NP_006210 (OMIM: 602925) phosphatidylinositol 4,5- (1070) 563 120.8 3.4e-26
NP_001308309 (OMIM: 603601) phosphatidylinositol 4 (1306) 564 121.1 3.4e-26
XP_011518488 (OMIM: 603601) PREDICTED: phosphatidy (1630) 564 121.2 4.1e-26
NP_001308307 (OMIM: 603601) phosphatidylinositol 4 (1686) 564 121.2 4.2e-26
NP_002636 (OMIM: 603601) phosphatidylinositol 4-ph (1686) 564 121.2 4.2e-26
XP_016873413 (OMIM: 603601) PREDICTED: phosphatidy (1686) 564 121.2 4.2e-26
XP_016856964 (OMIM: 602838) PREDICTED: phosphatidy (1070) 557 119.7 7.6e-26
XP_005245315 (OMIM: 602838) PREDICTED: phosphatidy (1607) 557 119.8 1e-25
>>NP_002638 (OMIM: 602609) phosphatidylinositol 3-kinase (887 aa)
initn: 5897 init1: 5897 opt: 5897 Z-score: 6228.1 bits: 1163.6 E(85289): 0
Smith-Waterman score: 5897; 100.0% identity (100.0% similar) in 887 aa overlap (1-887:1-887)
10 20 30 40 50 60
pF1KB9 MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 AHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 DESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 SYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 EDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 DSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTFLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 LLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 IRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 ENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 VMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 KEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVK
790 800 810 820 830 840
850 860 870 880
pF1KB9 KVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
850 860 870 880
>>NP_001294949 (OMIM: 602609) phosphatidylinositol 3-kin (824 aa)
initn: 5461 init1: 5319 opt: 5319 Z-score: 5617.9 bits: 1050.6 E(85289): 0
Smith-Waterman score: 5339; 92.9% identity (92.9% similar) in 887 aa overlap (1-887:1-824)
10 20 30 40 50 60
pF1KB9 MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVT
:::::::::::::::::::::::
NP_001 MGEAEKFHYIYSCDLDINVQLKI-------------------------------------
10 20
70 80 90 100 110 120
pF1KB9 CQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAV
::::::::::::::::::::::::::::::::::
NP_001 --------------------------WNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAV
30 40 50
130 140 150 160 170 180
pF1KB9 PVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTK
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB9 AHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDG
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB9 DESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIV
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB9 SYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDV
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB9 EDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKK
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB9 DSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTFLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTFLI
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB9 SRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRS
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB9 LLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVK
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB9 IRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRK
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB9 ENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAE
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB9 VMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLN
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB9 KEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVK
720 730 740 750 760 770
850 860 870 880
pF1KB9 KVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
780 790 800 810 820
>>XP_011524333 (OMIM: 602609) PREDICTED: phosphatidylino (701 aa)
initn: 4622 init1: 4622 opt: 4622 Z-score: 4882.4 bits: 914.2 E(85289): 0
Smith-Waterman score: 4622; 100.0% identity (100.0% similar) in 701 aa overlap (187-887:1-701)
160 170 180 190 200 210
pF1KB9 TKTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMY
::::::::::::::::::::::::::::::
XP_011 MVKVDWLDRLTFREIEMINESEKRSSNFMY
10 20 30
220 230 240 250 260 270
pF1KB9 LMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARS
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB9 LRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKC
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB9 VNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB9 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB9 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB9 YLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQAL
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB9 LGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFK
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB9 HGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDT
460 470 480 490 500 510
700 710 720 730 740 750
pF1KB9 EGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGK
520 530 540 550 560 570
760 770 780 790 800 810
pF1KB9 LFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLI
580 590 600 610 620 630
820 830 840 850 860 870
pF1KB9 LNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVE
640 650 660 670 680 690
880
pF1KB9 QIHKFAQYWRK
:::::::::::
XP_011 QIHKFAQYWRK
700
>>XP_016874968 (OMIM: 609001) PREDICTED: phosphatidylino (817 aa)
initn: 605 init1: 215 opt: 612 Z-score: 644.7 bits: 130.3 E(85289): 3.6e-29
Smith-Waterman score: 673; 26.9% identity (57.0% similar) in 595 aa overlap (308-883:35-544)
280 290 300 310 320 330
pF1KB9 RSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCV
:. :.. .: .:.: .:.. .: : .
XP_016 SEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSA
10 20 30 40 50 60
340 350 360 370 380 390
pF1KB9 -NWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
.:: . ... .: .: . ..: ::.: . . .:. :: .: . ...:: ::
XP_016 PGWD-ERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYL
70 80 90 100 110 120
400 410 420 430 440 450
pF1KB9 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
:::::.:.:
XP_016 PQLVQAVKFE--------------------------------------------------
130
460 470 480 490 500 510
pF1KB9 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
:::. : .:. :. .. .:. ::: . .... .:
XP_016 ------------WNLESPLVQLLLHRSLQSIQVAHRLYWLL------KNAE------NEA
140 150 160
520 530 540 550 560 570
pF1KB9 YLNVMRRFSQALLKGDK--SVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQ
:. . . : :: . . . ... . .. .: .. : . . :. : .... : :.
XP_016 YF---KSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQ--EVLK
170 180 190 200 210 220
580 590 600 610 620 630
pF1KB9 ALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTED--GGKYP
.: :.. ..::. :::.: . :.:: .. . : : .: .. : . . : .
XP_016 KEIGRLEEF-FQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNIS
230 240 250 260 270 280
640 650 660 670 680 690
pF1KB9 VIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFI-QSVPVA
.::: :::::::.:.::.:..::.. .:.::... :. :.:. .:..:.. ..: .:
XP_016 IIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLA
290 300 310 320 330 340
700 710 720 730 740
pF1KB9 EVLDTEGSI----QNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLD
.. : : .: ..:. ..: .. ... .. ::::.::.:.:::: ::: :
XP_016 KIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHND
350 360 370 380 390 400
750 760 770 780 790
pF1KB9 NLLLTKTGKLFHIDFGYILG---------RDPKPLPPPMKLNKEMVEGMGGTQSEQYQEF
:..:::.:..:::::: .:: :: :. ... ..:: : . ...:.:
XP_016 NIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG--GKNPQHFQDF
410 420 430 440 450 460
800 810 820 830 840 850
pF1KB9 RKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHY
. : :. .:..:.:.:::. .:. :..:... : .: : ...: . .: ::. .
XP_016 VELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQD--LKYVYNNLRPQDTDLEATSH
470 480 490 500 510
860 870 880
pF1KB9 MQSLIDESVHALFAAVVEQIHKFAQYWRK
. . : ::.. . . . . :: .::
XP_016 FTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGF
520 530 540 550 560 570
>>NP_001275703 (OMIM: 609001) phosphatidylinositol 4-pho (1264 aa)
initn: 666 init1: 215 opt: 612 Z-score: 642.1 bits: 130.5 E(85289): 5e-29
Smith-Waterman score: 673; 26.9% identity (57.0% similar) in 595 aa overlap (308-883:488-997)
280 290 300 310 320 330
pF1KB9 RSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCV
:. :.. .: .:.: .:.. .: : .
NP_001 SEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSA
460 470 480 490 500 510
340 350 360 370 380 390
pF1KB9 -NWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
.:: . ... .: .: . ..: ::.: . . .:. :: .: . ...:: ::
NP_001 PGWD-ERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYL
520 530 540 550 560 570
400 410 420 430 440 450
pF1KB9 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
:::::.:.:
NP_001 PQLVQAVKFE--------------------------------------------------
580
460 470 480 490 500 510
pF1KB9 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
:::. : .:. :. .. .:. ::: . .... .:
NP_001 ------------WNLESPLVQLLLHRSLQSIQVAHRLYWLL------KNAE------NEA
590 600 610 620
520 530 540 550 560 570
pF1KB9 YLNVMRRFSQALLKGDK--SVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQ
:. . . : :: . . . ... . .. .: .. : . . :. : .... : :.
NP_001 YF---KSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQ--EVLK
630 640 650 660 670
580 590 600 610 620 630
pF1KB9 ALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTED--GGKYP
.: :.. ..::. :::.: . :.:: .. . : : .: .. : . . : .
NP_001 KEIGRLEEF-FQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNIS
680 690 700 710 720 730
640 650 660 670 680 690
pF1KB9 VIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFI-QSVPVA
.::: :::::::.:.::.:..::.. .:.::... :. :.:. .:..:.. ..: .:
NP_001 IIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLA
740 750 760 770 780 790
700 710 720 730 740
pF1KB9 EVLDTEGSI----QNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLD
.. : : .: ..:. ..: .. ... .. ::::.::.:.:::: ::: :
NP_001 KIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHND
800 810 820 830 840 850
750 760 770 780 790
pF1KB9 NLLLTKTGKLFHIDFGYILG---------RDPKPLPPPMKLNKEMVEGMGGTQSEQYQEF
:..:::.:..:::::: .:: :: :. ... ..:: : . ...:.:
NP_001 NIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG--GKNPQHFQDF
860 870 880 890 900 910
800 810 820 830 840 850
pF1KB9 RKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHY
. : :. .:..:.:.:::. .:. :..:... : .: : ...: . .: ::. .
NP_001 VELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQD--LKYVYNNLRPQDTDLEATSH
920 930 940 950 960 970
860 870 880
pF1KB9 MQSLIDESVHALFAAVVEQIHKFAQYWRK
. . : ::.. . . . . :: .::
NP_001 FTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGF
980 990 1000 1010 1020 1030
>>XP_016874966 (OMIM: 609001) PREDICTED: phosphatidylino (1270 aa)
initn: 666 init1: 215 opt: 612 Z-score: 642.0 bits: 130.5 E(85289): 5e-29
Smith-Waterman score: 673; 26.9% identity (57.0% similar) in 595 aa overlap (308-883:488-997)
280 290 300 310 320 330
pF1KB9 RSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCV
:. :.. .: .:.: .:.. .: : .
XP_016 SEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSA
460 470 480 490 500 510
340 350 360 370 380 390
pF1KB9 -NWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
.:: . ... .: .: . ..: ::.: . . .:. :: .: . ...:: ::
XP_016 PGWD-ERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYL
520 530 540 550 560 570
400 410 420 430 440 450
pF1KB9 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
:::::.:.:
XP_016 PQLVQAVKFE--------------------------------------------------
580
460 470 480 490 500 510
pF1KB9 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
:::. : .:. :. .. .:. ::: . .... .:
XP_016 ------------WNLESPLVQLLLHRSLQSIQVAHRLYWLL------KNAE------NEA
590 600 610 620
520 530 540 550 560 570
pF1KB9 YLNVMRRFSQALLKGDK--SVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQ
:. . . : :: . . . ... . .. .: .. : . . :. : .... : :.
XP_016 YF---KSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQ--EVLK
630 640 650 660 670
580 590 600 610 620 630
pF1KB9 ALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTED--GGKYP
.: :.. ..::. :::.: . :.:: .. . : : .: .. : . . : .
XP_016 KEIGRLEEF-FQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNIS
680 690 700 710 720 730
640 650 660 670 680 690
pF1KB9 VIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFI-QSVPVA
.::: :::::::.:.::.:..::.. .:.::... :. :.:. .:..:.. ..: .:
XP_016 IIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLA
740 750 760 770 780 790
700 710 720 730 740
pF1KB9 EVLDTEGSI----QNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLD
.. : : .: ..:. ..: .. ... .. ::::.::.:.:::: ::: :
XP_016 KIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHND
800 810 820 830 840 850
750 760 770 780 790
pF1KB9 NLLLTKTGKLFHIDFGYILG---------RDPKPLPPPMKLNKEMVEGMGGTQSEQYQEF
:..:::.:..:::::: .:: :: :. ... ..:: : . ...:.:
XP_016 NIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG--GKNPQHFQDF
860 870 880 890 900 910
800 810 820 830 840 850
pF1KB9 RKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHY
. : :. .:..:.:.:::. .:. :..:... : .: : ...: . .: ::. .
XP_016 VELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQD--LKYVYNNLRPQDTDLEATSH
920 930 940 950 960 970
860 870 880
pF1KB9 MQSLIDESVHALFAAVVEQIHKFAQYWRK
. . : ::.. . . . . :: .::
XP_016 FTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGF
980 990 1000 1010 1020 1030
>>XP_016874965 (OMIM: 609001) PREDICTED: phosphatidylino (1407 aa)
initn: 605 init1: 215 opt: 612 Z-score: 641.4 bits: 130.5 E(85289): 5.5e-29
Smith-Waterman score: 673; 26.9% identity (57.0% similar) in 595 aa overlap (308-883:625-1134)
280 290 300 310 320 330
pF1KB9 RSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCV
:. :.. .: .:.: .:.. .: : .
XP_016 SEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSA
600 610 620 630 640 650
340 350 360 370 380 390
pF1KB9 -NWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
.:: . ... .: .: . ..: ::.: . . .:. :: .: . ...:: ::
XP_016 PGWD-ERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYL
660 670 680 690 700 710
400 410 420 430 440 450
pF1KB9 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
:::::.:.:
XP_016 PQLVQAVKFE--------------------------------------------------
720
460 470 480 490 500 510
pF1KB9 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
:::. : .:. :. .. .:. ::: . .... .:
XP_016 ------------WNLESPLVQLLLHRSLQSIQVAHRLYWLL------KNAE------NEA
730 740 750
520 530 540 550 560 570
pF1KB9 YLNVMRRFSQALLKGDK--SVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQ
:. . . : :: . . . ... . .. .: .. : . . :. : .... : :.
XP_016 YF---KSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQ--EVLK
760 770 780 790 800 810
580 590 600 610 620 630
pF1KB9 ALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTED--GGKYP
.: :.. ..::. :::.: . :.:: .. . : : .: .. : . . : .
XP_016 KEIGRLEEF-FQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNIS
820 830 840 850 860 870
640 650 660 670 680 690
pF1KB9 VIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFI-QSVPVA
.::: :::::::.:.::.:..::.. .:.::... :. :.:. .:..:.. ..: .:
XP_016 IIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLA
880 890 900 910 920 930
700 710 720 730 740
pF1KB9 EVLDTEGSI----QNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLD
.. : : .: ..:. ..: .. ... .. ::::.::.:.:::: ::: :
XP_016 KIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHND
940 950 960 970 980 990
750 760 770 780 790
pF1KB9 NLLLTKTGKLFHIDFGYILG---------RDPKPLPPPMKLNKEMVEGMGGTQSEQYQEF
:..:::.:..:::::: .:: :: :. ... ..:: : . ...:.:
XP_016 NIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG--GKNPQHFQDF
1000 1010 1020 1030 1040 1050
800 810 820 830 840 850
pF1KB9 RKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHY
. : :. .:..:.:.:::. .:. :..:... : .: : ...: . .: ::. .
XP_016 VELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQD--LKYVYNNLRPQDTDLEATSH
1060 1070 1080 1090 1100
860 870 880
pF1KB9 MQSLIDESVHALFAAVVEQIHKFAQYWRK
. . : ::.. . . . . :: .::
XP_016 FTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGF
1110 1120 1130 1140 1150 1160
>>XP_016874964 (OMIM: 609001) PREDICTED: phosphatidylino (1437 aa)
initn: 666 init1: 215 opt: 612 Z-score: 641.3 bits: 130.5 E(85289): 5.6e-29
Smith-Waterman score: 673; 26.9% identity (57.0% similar) in 595 aa overlap (308-883:710-1219)
280 290 300 310 320 330
pF1KB9 RSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCV
:. :.. .: .:.: .:.. .: : .
XP_016 SEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSA
680 690 700 710 720 730
340 350 360 370 380 390
pF1KB9 -NWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
.:: . ... .: .: . ..: ::.: . . .:. :: .: . ...:: ::
XP_016 PGWD-ERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYL
740 750 760 770 780 790
400 410 420 430 440 450
pF1KB9 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
:::::.:.:
XP_016 PQLVQAVKFE--------------------------------------------------
800
460 470 480 490 500 510
pF1KB9 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
:::. : .:. :. .. .:. ::: . .... .:
XP_016 ------------WNLESPLVQLLLHRSLQSIQVAHRLYWLL------KNAE------NEA
810 820 830 840
520 530 540 550 560 570
pF1KB9 YLNVMRRFSQALLKGDK--SVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQ
:. . . : :: . . . ... . .. .: .. : . . :. : .... : :.
XP_016 YF---KSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQ--EVLK
850 860 870 880 890
580 590 600 610 620 630
pF1KB9 ALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTED--GGKYP
.: :.. ..::. :::.: . :.:: .. . : : .: .. : . . : .
XP_016 KEIGRLEEF-FQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNIS
900 910 920 930 940 950
640 650 660 670 680 690
pF1KB9 VIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFI-QSVPVA
.::: :::::::.:.::.:..::.. .:.::... :. :.:. .:..:.. ..: .:
XP_016 IIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLA
960 970 980 990 1000 1010
700 710 720 730 740
pF1KB9 EVLDTEGSI----QNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLD
.. : : .: ..:. ..: .. ... .. ::::.::.:.:::: ::: :
XP_016 KIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHND
1020 1030 1040 1050 1060 1070
750 760 770 780 790
pF1KB9 NLLLTKTGKLFHIDFGYILG---------RDPKPLPPPMKLNKEMVEGMGGTQSEQYQEF
:..:::.:..:::::: .:: :: :. ... ..:: : . ...:.:
XP_016 NIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG--GKNPQHFQDF
1080 1090 1100 1110 1120 1130
800 810 820 830 840 850
pF1KB9 RKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHY
. : :. .:..:.:.:::. .:. :..:... : .: : ...: . .: ::. .
XP_016 VELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQD--LKYVYNNLRPQDTDLEATSH
1140 1150 1160 1170 1180 1190
860 870 880
pF1KB9 MQSLIDESVHALFAAVVEQIHKFAQYWRK
. . : ::.. . . . . :: .::
XP_016 FTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGF
1200 1210 1220 1230 1240 1250
>>XP_011518999 (OMIM: 609001) PREDICTED: phosphatidylino (1442 aa)
initn: 666 init1: 215 opt: 612 Z-score: 641.3 bits: 130.5 E(85289): 5.6e-29
Smith-Waterman score: 673; 26.9% identity (57.0% similar) in 595 aa overlap (308-883:710-1219)
280 290 300 310 320 330
pF1KB9 RSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCV
:. :.. .: .:.: .:.. .: : .
XP_011 SEENRSNLEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSA
680 690 700 710 720 730
340 350 360 370 380 390
pF1KB9 -NWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYL
.:: . ... .: .: . ..: ::.: . . .:. :: .: . ...:: ::
XP_011 PGWD-ERTVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYL
740 750 760 770 780 790
400 410 420 430 440 450
pF1KB9 LQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSP
:::::.:.:
XP_011 PQLVQAVKFE--------------------------------------------------
800
460 470 480 490 500 510
pF1KB9 PPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEM
:::. : .:. :. .. .:. ::: . .... .:
XP_011 ------------WNLESPLVQLLLHRSLQSIQVAHRLYWLL------KNAE------NEA
810 820 830 840
520 530 540 550 560 570
pF1KB9 YLNVMRRFSQALLKGDK--SVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQ
:. . . : :: . . . ... . .. .: .. : . . :. : .... : :.
XP_011 YF---KSWYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVKSASDHQRQ--EVLK
850 860 870 880 890
580 590 600 610 620 630
pF1KB9 ALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTED--GGKYP
.: :.. ..::. :::.: . :.:: .. . : : .: .. : . . : .
XP_011 KEIGRLEEF-FQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNIS
900 910 920 930 940 950
640 650 660 670 680 690
pF1KB9 VIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFI-QSVPVA
.::: :::::::.:.::.:..::.. .:.::... :. :.:. .:..:.. ..: .:
XP_011 IIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLA
960 970 980 990 1000 1010
700 710 720 730 740
pF1KB9 EVLDTEGSI----QNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLD
.. : : .: ..:. ..: .. ... .. ::::.::.:.:::: ::: :
XP_011 KIHRHSGLIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHND
1020 1030 1040 1050 1060 1070
750 760 770 780 790
pF1KB9 NLLLTKTGKLFHIDFGYILG---------RDPKPLPPPMKLNKEMVEGMGGTQSEQYQEF
:..:::.:..:::::: .:: :: :. ... ..:: : . ...:.:
XP_011 NIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG--GKNPQHFQDF
1080 1090 1100 1110 1120 1130
800 810 820 830 840 850
pF1KB9 RKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHY
. : :. .:..:.:.:::. .:. :..:... : .: : ...: . .: ::. .
XP_011 VELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQD--LKYVYNNLRPQDTDLEATSH
1140 1150 1160 1170 1180 1190
860 870 880
pF1KB9 MQSLIDESVHALFAAVVEQIHKFAQYWRK
. . : ::.. . . . . :: .::
XP_011 FTKKIKESLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGF
1200 1210 1220 1230 1240 1250
>>NP_004561 (OMIM: 609001) phosphatidylinositol 4-phosph (1445 aa)
initn: 605 init1: 215 opt: 612 Z-score: 641.3 bits: 130.5 E(85289): 5.6e-29
Smith-Waterman score: 675; 25.0% identity (55.5% similar) in 768 aa overlap (155-883:506-1178)
130 140 150 160 170 180
pF1KB9 TTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQ
.:...: : .: :. :.:. . :
NP_004 KGLIEKVTTELSTSIYQLINVYCNSFYADFQPVNVP-RCTSYLNPGLPSHLSFTVYA---
480 490 500 510 520 530
190 200 210 220 230
pF1KB9 GHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIV------YYEK
.: . :. :..: .:. .: : : .: :.. . : .. ... . :
NP_004 AHNIPETWVHRINF-PLEI--KSLPRES---MLTVKLFGIACATNNANLLAWTCLPLFPK
540 550 560 570 580
240 250 260 270 280 290
pF1KB9 DGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSD--HDLKPNAA-TRDQ
. . . .: :. : . : .: .. . .. . . . :. . .::.. .:..
NP_004 EKSILGSMLFSMTLQSEPPVEMITPGVWDVSQPSPVTLQIDFPATGWEYMKPDSEENRSN
590 600 610 620 630 640
300 310 320 330 340
pF1KB9 LNII-------VSYPPTKQ----LTYEEQDLVWKFRYYLTNQEKALTKFLKCV-NWDLPQ
:. .. :: :. :.. .: .:.: .:.. .: : . .:: .
NP_004 LEEPLKECIKHIARLSQKQTPLLLSEEKKRYLWFYRFYCNNENCSLPLVLGSAPGWD-ER
650 660 670 680 690 700
350 360 370 380 390 400
pF1KB9 EAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQAL
... .: .: . ..: ::.: . . .:. :: .: . ...:: :: :::::.
NP_004 TVSEMHTILRRWTFSQPLEALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAV
710 720 730 740 750 760
410 420 430 440 450 460
pF1KB9 KYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTK
:.:
NP_004 KFE---------------------------------------------------------
470 480 490 500 510 520
pF1KB9 EVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRR
:::. : .:. :. .. .:. ::: . .... .: :. .
NP_004 -----WNLESPLVQLLLHRSLQSIQVAHRLYWLL------KNAE------NEAYF---KS
770 780 790 800
530 540 550 560 570 580
pF1KB9 FSQALLKGDK--SVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNE
. : :: . . . ... . .. .: .. : . . :. :.. ....: :. .: :
NP_004 WYQKLLAALQFCAGKALNDEFSKEQKLIKILGDIGERVK--SASDHQRQEVLKKEIGRLE
810 820 830 840 850 860
590 600 610 620 630
pF1KB9 KMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTED--GGKYPVIFKHGD
.. ..::. :::.: . :.:: .. . : : .: .. : . . : . .::: ::
NP_004 EF-FQDVNTCHLPLNPALCIKGIDHDACSYFTSNALPLKITFINANPMGKNISIIFKAGD
870 880 890 900 910 920
640 650 660 670 680 690
pF1KB9 DLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFI-QSVPVAEVLDTEG
:::::.:.::.:..::.. .:.::... :. :.:. .:..:.. ..: .:.. :
NP_004 DLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLAKIHRHSG
930 940 950 960 970 980
700 710 720 730 740 750
pF1KB9 SI----QNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKT
: .: ..:. ..: .. ... .. ::::.::.:.:::: ::: ::..:::.
NP_004 LIGPLKENTIKKWFSQHNHLKADYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKS
990 1000 1010 1020 1030 1040
760 770 780 790 800
pF1KB9 GKLFHIDFGYILG---------RDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTA
:..:::::: .:: :: :. ... ..:: : . ...:.: . : :
NP_004 GHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEG--GKNPQHFQDFVELCCRA
1050 1060 1070 1080 1090 1100
810 820 830 840 850 860
pF1KB9 FLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDE
. .:..:.:.:::. .:. :..:... : .: : ...: . .: ::. .. . : :
NP_004 YNIIRKHSQLLLNLLEMMLYAGLPELSGIQD--LKYVYNNLRPQDTDLEATSHFTKKIKE
1110 1120 1130 1140 1150 1160
870 880
pF1KB9 SVHALFAAVVEQIHKFAQYWRK
:.. . . . . :: .::
NP_004 SLECFPVKLNNLIHTLAQMSAISPAKSTSQTFPQESCLLSTTRSIERATILGFSKKSSNL
1170 1180 1190 1200 1210 1220
887 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:51:43 2016 done: Fri Nov 4 18:51:45 2016
Total Scan time: 9.070 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]