Result of FASTA (omim) for
pF1KB9657
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9657, 202 aa
1>>>pF1KB9657 202 - 202 aa - 202 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0484+/-0.000363; mu= 4.6140+/- 0.023
mean_var=313.8757+/-64.586, 0's: 0 Z-trim(124.0): 53 B-trim: 1097 in 1/53
Lambda= 0.072393
statistics sampled from 44789 (44871) to 44789 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.526), width: 16
Scan time: 6.380
The best scores are: opt bits E(85289)
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202) 1356 153.8 1.8e-37
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202) 1356 153.8 1.8e-37
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 655 80.4 1.7e-15
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 655 80.4 1.7e-15
NP_005089 (OMIM: 603628) musculin [Homo sapiens] ( 206) 271 40.4 0.0024
NP_689627 (OMIM: 613483) class E basic helix-loop- ( 381) 268 40.5 0.0042
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201) 261 39.4 0.0048
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201) 261 39.4 0.0048
>>XP_011513798 (OMIM: 101400,123100,180750,601622) PREDI (202 aa)
initn: 1356 init1: 1356 opt: 1356 Z-score: 793.7 bits: 153.8 E(85289): 1.8e-37
Smith-Waterman score: 1356; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KB9 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
130 140 150 160 170 180
190 200
pF1KB9 ERLSYAFSVWRMEGAWSMSASH
::::::::::::::::::::::
XP_011 ERLSYAFSVWRMEGAWSMSASH
190 200
>>NP_000465 (OMIM: 101400,123100,180750,601622) twist-re (202 aa)
initn: 1356 init1: 1356 opt: 1356 Z-score: 793.7 bits: 153.8 E(85289): 1.8e-37
Smith-Waterman score: 1356; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KB9 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
130 140 150 160 170 180
190 200
pF1KB9 ERLSYAFSVWRMEGAWSMSASH
::::::::::::::::::::::
NP_000 ERLSYAFSVWRMEGAWSMSASH
190 200
>>NP_001258822 (OMIM: 200110,209885,227260,607556) twist (160 aa)
initn: 744 init1: 640 opt: 655 Z-score: 399.1 bits: 80.4 E(85289): 1.7e-15
Smith-Waterman score: 750; 66.7% identity (75.6% similar) in 201 aa overlap (2-202:1-160)
10 20 30 40 50 60
pF1KB9 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
:.. :::::::.: ::..:::: .:: : :: ::::: :..:.
NP_001 MEEGSSSPVSPVD-SLGTSEEELERQ-P---KRFGRKRRYSKKSS--------------
10 20 30 40
70 80 90 100 110 120
pF1KB9 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
: :::. :::::: :. : ::.::::.::..::::::::
NP_001 ----EDGSPTPGKRGKK------------------GSPSAQSFEELQSQRILANVRERQR
50 60 70
130 140 150 160 170 180
pF1KB9 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
:::::::::::::::::::::::::::::::::::::::::::::::.:.::.:::::::
NP_001 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAH
80 90 100 110 120 130
190 200
pF1KB9 ERLSYAFSVWRMEGAWSMSASH
::::::::::::::::::::::
NP_001 ERLSYAFSVWRMEGAWSMSASH
140 150 160
>>NP_476527 (OMIM: 200110,209885,227260,607556) twist-re (160 aa)
initn: 744 init1: 640 opt: 655 Z-score: 399.1 bits: 80.4 E(85289): 1.7e-15
Smith-Waterman score: 750; 66.7% identity (75.6% similar) in 201 aa overlap (2-202:1-160)
10 20 30 40 50 60
pF1KB9 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
:.. :::::::.: ::..:::: .:: : :: ::::: :..:.
NP_476 MEEGSSSPVSPVD-SLGTSEEELERQ-P---KRFGRKRRYSKKSS--------------
10 20 30 40
70 80 90 100 110 120
pF1KB9 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
: :::. :::::: :. : ::.::::.::..::::::::
NP_476 ----EDGSPTPGKRGKK------------------GSPSAQSFEELQSQRILANVRERQR
50 60 70
130 140 150 160 170 180
pF1KB9 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
:::::::::::::::::::::::::::::::::::::::::::::::.:.::.:::::::
NP_476 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAH
80 90 100 110 120 130
190 200
pF1KB9 ERLSYAFSVWRMEGAWSMSASH
::::::::::::::::::::::
NP_476 ERLSYAFSVWRMEGAWSMSASH
140 150 160
>>NP_005089 (OMIM: 603628) musculin [Homo sapiens] (206 aa)
initn: 416 init1: 170 opt: 271 Z-score: 181.2 bits: 40.4 E(85289): 0.0024
Smith-Waterman score: 271; 34.7% identity (58.5% similar) in 193 aa overlap (5-189:1-184)
10 20 30 40 50
pF1KB9 MMQDVSSSPVS-PADDSLSNSEEE---PDRQQPPSGKRGGRKRRSS--RRSAGGGAGPGG
.:.. :: : . : . ..: : ..:: :: .. .: :.. : :
NP_005 MSTGSVSDPEEMELRGLQREYPVPASKRPP--LRGVERSYASPSDNSSAEEEDPDG
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 AAGGGVGGGDEPGSPAQGKRGK-KSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMA
. : :: :: . . :: ::.::..::::.. .. .. : :.:: :
NP_005 EEERCALG--TAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 NVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKM
:.::: : . :..::. :. .: .: : ::::..::.::. :: : :.:: :. ..
NP_005 NARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN--
120 130 140 150 160 170
180 190 200
pF1KB9 ASCSYVAHERLSYAFSVWRMEGAWSMSASH
.:: :.. : :
NP_005 ---GYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
180 190 200
>>NP_689627 (OMIM: 613483) class E basic helix-loop-heli (381 aa)
initn: 408 init1: 186 opt: 268 Z-score: 176.7 bits: 40.5 E(85289): 0.0042
Smith-Waterman score: 290; 38.6% identity (61.4% similar) in 171 aa overlap (6-164:142-301)
10 20
pF1KB9 MMQDVSSSPVSPADDSLSNSE-------EEPDRQQ
:.. :: ::: . : .: : .
NP_689 GDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADP-RAS
120 130 140 150 160 170
30 40 50 60 70 80
pF1KB9 PPSGKRGGRKRR--SSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGG
: .: :.. . :. . ::.. : :. ::: :::. :: .: :::.:
NP_689 PGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGS----------SGGGGGSG
180 190 200 210 220
90 100 110 120 130 140
pF1KB9 AGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTL--PS-DKL
.:.::.:::...: .. .: .. :. :.:::.: ..::.:. :: .:: :: ::
NP_689 SGSGGSSSSSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKL
230 240 250 260 270 280
150 160 170 180 190 200
pF1KB9 SKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
::: :: :: :: . :.:.
NP_689 SKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGA
290 300 310 320 330 340
>>XP_006716679 (OMIM: 609067) PREDICTED: basic helix-loo (201 aa)
initn: 304 init1: 155 opt: 261 Z-score: 175.6 bits: 39.4 E(85289): 0.0048
Smith-Waterman score: 261; 44.8% identity (65.5% similar) in 116 aa overlap (62-175:29-143)
40 50 60 70 80 90
pF1KB9 GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGG
:.: :: . : ..: :: :. .:
XP_006 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCR-VHAARCGLQGARRRAG
10 20 30 40 50
100 110 120 130 140
pF1KB9 GSSSGGGSPQSYEELQT-QRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTL
: .:::.: . . :: ::.:::.::.:.: ::.::: .::: :.: :::::.::
XP_006 GRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETL
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB9 KLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
.::. ::. : .:: . : . :
XP_006 RLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPKQ
120 130 140 150 160 170
>>NP_001073983 (OMIM: 609067) basic helix-loop-helix tra (201 aa)
initn: 304 init1: 155 opt: 261 Z-score: 175.6 bits: 39.4 E(85289): 0.0048
Smith-Waterman score: 261; 44.8% identity (65.5% similar) in 116 aa overlap (62-175:29-143)
40 50 60 70 80 90
pF1KB9 GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGG
:.: :: . : ..: :: :. .:
NP_001 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCR-VHAARCGLQGARRRAG
10 20 30 40 50
100 110 120 130 140
pF1KB9 GSSSGGGSPQSYEELQT-QRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTL
: .:::.: . . :: ::.:::.::.:.: ::.::: .::: :.: :::::.::
NP_001 GRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETL
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB9 KLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
.::. ::. : .:: . : . :
NP_001 RLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPKQ
120 130 140 150 160 170
202 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:19:56 2016 done: Sat Nov 5 14:19:57 2016
Total Scan time: 6.380 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]