Result of FASTA (omim) for
pF1KB9643
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9643, 407 aa
1>>>pF1KB9643 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8834+/-0.000386; mu= 16.6412+/- 0.024
mean_var=144.6611+/-30.011, 0's: 0 Z-trim(116.4): 234 B-trim: 0 in 0/58
Lambda= 0.106635
statistics sampled from 27211 (27506) to 27211 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.323), width: 16
Scan time: 8.260
The best scores are: opt bits E(85289)
NP_998755 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 2752 435.2 1.4e-121
NP_434698 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 2752 435.2 1.4e-121
NP_005789 (OMIM: 605661) E3 ubiquitin-protein liga ( 407) 2752 435.2 1.4e-121
NP_001007279 (OMIM: 605661) E3 ubiquitin-protein l ( 410) 2752 435.2 1.4e-121
NP_775107 (OMIM: 616148) tripartite motif-containi ( 403) 724 123.2 1.2e-27
NP_060543 (OMIM: 613184) E3 ubiquitin-protein liga ( 485) 357 66.8 1.3e-10
NP_060677 (OMIM: 616755) E3 ubiquitin-protein liga ( 475) 334 63.3 1.5e-09
XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 555) 334 63.4 1.6e-09
NP_439893 (OMIM: 605701) tripartite motif-containi ( 395) 319 60.9 6.5e-09
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 320 61.1 6.7e-09
NP_006769 (OMIM: 605701) tripartite motif-containi ( 481) 319 61.0 7.4e-09
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 316 60.5 1.1e-08
NP_001186502 (OMIM: 606559) E3 ubiquitin-protein l ( 494) 310 59.6 2e-08
NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 309 59.4 2.2e-08
XP_011518729 (OMIM: 608487) PREDICTED: tripartite ( 271) 302 58.0 3.2e-08
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 302 58.4 4.7e-08
XP_006718421 (OMIM: 608487) PREDICTED: tripartite ( 265) 298 57.4 4.8e-08
XP_016873952 (OMIM: 608487) PREDICTED: tripartite ( 265) 298 57.4 4.8e-08
XP_016873951 (OMIM: 608487) PREDICTED: tripartite ( 300) 298 57.5 5.2e-08
XP_011518728 (OMIM: 608487) PREDICTED: tripartite ( 310) 298 57.5 5.3e-08
XP_016873950 (OMIM: 608487) PREDICTED: tripartite ( 310) 298 57.5 5.3e-08
XP_016873949 (OMIM: 608487) PREDICTED: tripartite ( 314) 298 57.5 5.3e-08
NP_149084 (OMIM: 608487) tripartite motif-containi ( 326) 298 57.5 5.4e-08
XP_005253241 (OMIM: 608487) PREDICTED: tripartite ( 326) 298 57.5 5.4e-08
NP_149083 (OMIM: 608487) tripartite motif-containi ( 347) 298 57.6 5.7e-08
XP_005253240 (OMIM: 608487) PREDICTED: tripartite ( 493) 298 57.8 7.1e-08
NP_149023 (OMIM: 608487) tripartite motif-containi ( 493) 298 57.8 7.1e-08
NP_001128327 (OMIM: 606123) E3 ubiquitin-protein l ( 343) 295 57.1 7.7e-08
NP_569074 (OMIM: 605684) tripartite motif-containi ( 270) 292 56.5 9.2e-08
XP_011542512 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 295 57.3 9.5e-08
NP_057186 (OMIM: 606123) E3 ubiquitin-protein liga ( 477) 295 57.3 9.5e-08
NP_001020111 (OMIM: 606123) E3 ubiquitin-protein l ( 477) 295 57.3 9.5e-08
XP_011542511 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 295 57.3 9.5e-08
XP_006711842 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 295 57.3 9.5e-08
NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 292 56.8 1.3e-07
NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 292 56.8 1.3e-07
XP_016856907 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 262) 288 55.9 1.4e-07
XP_016856908 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 262) 288 55.9 1.4e-07
XP_011512567 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 421) 287 56.0 2.1e-07
NP_008959 (OMIM: 609316) E3 ubiquitin-protein liga ( 425) 287 56.0 2.1e-07
XP_011512566 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 424) 284 55.5 2.9e-07
NP_150594 (OMIM: 605493) tripartite motif-containi ( 744) 285 56.0 3.7e-07
NP_006449 (OMIM: 605493) tripartite motif-containi ( 744) 285 56.0 3.7e-07
NP_001234935 (OMIM: 605493) tripartite motif-conta ( 744) 285 56.0 3.7e-07
XP_011518146 (OMIM: 605493) PREDICTED: tripartite ( 744) 285 56.0 3.7e-07
XP_016872587 (OMIM: 605493) PREDICTED: tripartite ( 744) 285 56.0 3.7e-07
NP_477514 (OMIM: 607564) tripartite motif-containi ( 488) 282 55.3 3.9e-07
NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516) 282 55.3 4e-07
XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 261) 273 53.6 6.8e-07
XP_011512527 (OMIM: 605701) PREDICTED: tripartite ( 413) 271 53.5 1.1e-06
>>NP_998755 (OMIM: 605661) E3 ubiquitin-protein ligase T (407 aa)
initn: 2752 init1: 2752 opt: 2752 Z-score: 2303.7 bits: 435.2 E(85289): 1.4e-121
Smith-Waterman score: 2752; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 GEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 DVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 DVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_998 QDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTK
310 320 330 340 350 360
370 380 390 400
pF1KB9 TADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_998 TADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
370 380 390 400
>>NP_434698 (OMIM: 605661) E3 ubiquitin-protein ligase T (407 aa)
initn: 2752 init1: 2752 opt: 2752 Z-score: 2303.7 bits: 435.2 E(85289): 1.4e-121
Smith-Waterman score: 2752; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_434 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_434 TSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_434 GEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_434 KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 DVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_434 DVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_434 QDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTK
310 320 330 340 350 360
370 380 390 400
pF1KB9 TADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_434 TADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
370 380 390 400
>>NP_005789 (OMIM: 605661) E3 ubiquitin-protein ligase T (407 aa)
initn: 2752 init1: 2752 opt: 2752 Z-score: 2303.7 bits: 435.2 E(85289): 1.4e-121
Smith-Waterman score: 2752; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 DVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTK
310 320 330 340 350 360
370 380 390 400
pF1KB9 TADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
370 380 390 400
>>NP_001007279 (OMIM: 605661) E3 ubiquitin-protein ligas (410 aa)
initn: 2752 init1: 2752 opt: 2752 Z-score: 2303.6 bits: 435.2 E(85289): 1.4e-121
Smith-Waterman score: 2752; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:4-410)
10 20 30 40 50
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDVMELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 RKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGIC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 ATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 DSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 AFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 SLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSY
310 320 330 340 350 360
360 370 380 390 400
pF1KB9 LTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
370 380 390 400 410
>>NP_775107 (OMIM: 616148) tripartite motif-containing p (403 aa)
initn: 640 init1: 244 opt: 724 Z-score: 617.6 bits: 123.2 E(85289): 1.2e-27
Smith-Waterman score: 724; 34.3% identity (70.6% similar) in 306 aa overlap (1-301:1-304)
10 20 30 40 50
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRP--APFKCPTCR
:. .::.:::::: :.:.:::::::::.::..:::.::..: .::: :.:::.::
NP_775 MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 K--ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI
. : . :::.:: ::..:..:.:::.. . : . .: : ::::..:: : .:.::
NP_775 SITEIAPTGIESLPVNFALRAIIEKYQQ-EDHPDIVTCPEHYRQPLNVYCLLDKKLVCGH
70 80 90 100 110
120 130 140 150 160 170
pF1KB9 CATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLT
: : :.: : . ....:: .:.:. ..:.... . : .. :. .: .: ...
NP_775 CLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 KDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIA
:.. : ..:..:. ::.:::. .:. . . . : : :.:.... : ..: . ..
NP_775 GDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 EAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSN-LPASPLMKNFDTSQWEDIKLVDVD
.... : :. ::..... :......:. ::: . . : .... .: .. ..
NP_775 ISLQEES-PLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 KLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFS
.. .:.
NP_775 NVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSE
300 310 320 330 340 350
>>NP_060543 (OMIM: 613184) E3 ubiquitin-protein ligase T (485 aa)
initn: 210 init1: 126 opt: 357 Z-score: 311.6 bits: 66.8 E(85289): 1.3e-10
Smith-Waterman score: 357; 26.5% identity (57.2% similar) in 283 aa overlap (1-270:7-282)
10 20 30 40 50
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKC
.: . :...:::: ... .: . :.:.::..:: :. : ... : . :
NP_060 MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNW---GYTC
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKM----PVCKGHLGQPLNIFCLTDM
: :: .. .:. :..: ..::: ... : : .:. : :. :..:: :.
NP_060 PLCRAPVQPR---NLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERH-GEKLKMFCKEDV
60 70 80 90 100 110
120 130 140 150 160
pF1KB9 QLICGICATRGEHTKHVFCSIEDA---YAQE-RDAFESLFQ-SFETWR-RGDALSRLDTL
..: :. :: : .::. : : ..:.: : . . :.:. . .: :
NP_060 LIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATW
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 ETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDP-EINKLN
. . . : .. . .: ....:: : : :. . . ... . .... :.:. .
NP_060 KIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB9 TILQEQRMAFNIAEAFKDVSEPIVF-LQQMQEFREKIKVIK-ETPLPPSNLPASPLMKNF
: : : . ::: . ..:. . ::..:: .. : . . : : :
NP_060 LIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLG
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB9 DTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLF
NP_060 LREILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCI
300 310 320 330 340 350
>>NP_060677 (OMIM: 616755) E3 ubiquitin-protein ligase T (475 aa)
initn: 218 init1: 105 opt: 334 Z-score: 292.5 bits: 63.3 E(85289): 1.5e-09
Smith-Waterman score: 337; 24.4% identity (56.3% similar) in 316 aa overlap (4-305:5-303)
10 20 30 40 50
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRK
:...: : :: :...:: : : : ::..: : : ::. . :: ::.
NP_060 MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRC---ITEHWVRQEAQ--GARDCPECRR
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 ETSATGINSLQVNYSLKGIVEKYNKIKISPKMPV------CKGHLGQPLNIFCLTDMQLI
. .: . .: .:::.:... .. . . :..: . ...::::: :.
NP_060 TFAEP---ALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH--DKVKLFCLTDRALL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 CGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQ
: .: . : .: .:.::. . . ... .:... .: . ..:. ::. .
NP_060 CFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSER----EHTEALQLLKRQLAE
120 130 140 150 160
180 190 200 210 220
pF1KB9 LLTKDSDK-----VKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQE
::.: : . : ::.:.. : .... .: ..:. .. . .... . :..
NP_060 --TKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRK
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 QRMAFNIAEAFKDVSEPIVFLQQMQEFREKIK-VIKETPLPPSNLPASPLMKNFDTSQWE
. . .: . .. .:: . . :..: :.:: : ..:.: .. . :.
NP_060 VQEGAQILQERLAETDRHTFLAGVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWK
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB9 DIKLVDVDKL--SLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLA
.. . :. . .: : ::
NP_060 SL-FQDIHPVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGS
290 300 310 320 330 340
>>XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquitin-pr (555 aa)
initn: 218 init1: 105 opt: 334 Z-score: 291.8 bits: 63.4 E(85289): 1.6e-09
Smith-Waterman score: 337; 24.4% identity (56.3% similar) in 316 aa overlap (4-305:85-383)
10 20 30
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKC
:...: : :: :...:: : : : ::..:
XP_016 AAAATGSSDSAGSGLRGCAGPKRWLLSSRGLKDELLCSICLSIYQDPVSLGCEHYFCRRC
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 LEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPV
: : ::. . :: ::. . .: . .: .:::.:... .. . .
XP_016 ---ITEHWVRQEAQ--GARDCPECRRTFAEP---ALAPSLKLANIVERYSSFPLDAILNA
120 130 140 150 160
100 110 120 130 140
pF1KB9 ------CKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQ
:..: . ...::::: :.: .: . : .: .:.::. . . ... .:
XP_016 RRAARPCQAH--DKVKLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQ
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB9 SFETWRRGDALSRLDTLETSKRKSLQLLTKDSDK-----VKEFFEKLQHTLDQKKNEILS
... .: . ..:. ::. . ::.: : . : ::.:.. : .... .:
XP_016 ALQDSER----EHTEALQLLKRQLAE--TKSSTKSLRTTIGEAFERLHRLLRERQKAMLE
230 240 250 260 270
210 220 230 240 250 260
pF1KB9 DFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIK-V
..:. .. . .... . :.. . . .: . .. .:: . . :..:
XP_016 ELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSERLKGK
280 290 300 310 320 330
270 280 290 300 310
pF1KB9 IKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKL--SLPQDTGTFISKIPWSFYKLFL
:.:: : ..:.: .. . :... . :. . .: : ::
XP_016 IHETNLTYEDFPTSKYTGPLQYTIWKSL-FQDIHPVPAALTLDPGTAHQRLILSDDCTIV
340 350 360 370 380 390
320 330 340 350 360 370
pF1KB9 LILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGF
XP_016 AYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASRKGS
400 410 420 430 440 450
>>NP_439893 (OMIM: 605701) tripartite motif-containing p (395 aa)
initn: 273 init1: 126 opt: 319 Z-score: 281.0 bits: 60.9 E(85289): 6.5e-09
Smith-Waterman score: 325; 23.7% identity (57.5% similar) in 299 aa overlap (4-281:10-297)
10 20 30 40 50
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKC
: ....:::: . . .: .. :.::::. :: : . . . .: :
NP_439 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCE--IPGPDLEESP-TC
10 20 30 40 50
60 70 80 90 100
pF1KB9 PTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKM-----PVCKGHLGQPLNIFCLTD
: : :: : :.. :..: ..::. ..... . ::. : :. . .:: :
NP_439 PLC-KEPFRPG--SFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEH-GEKIYFFCEDD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB9 MQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKR
. .: .: :::. :.. .::: : :. ... .. .. : . ...... :...
NP_439 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKER--EEIQEIQSRENKRM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 KSL--QLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDP-------EIN
. : :. :: .. ..:: .:.. :..... .:...:.. ... : ::
NP_439 QVLLTQVSTKRQQVISEF-AHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
180 190 200 210 220 230
230 240 250 260 270
pF1KB9 KLNTILQE--QRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET-----PLPPSNLP
.......: .. : . :. .. . .. :. . : : .: . ::
NP_439 RFSALIEELEEKNERPARELLTDIRSTLIRCET-RKCRKPVAVSPELGQRIRDFPQQALP
240 250 260 270 280
280 290 300 310 320 330
pF1KB9 ASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPT
. :: :
NP_439 LQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFD
290 300 310 320 330 340
>>NP_742013 (OMIM: 605700) E3 ubiquitin-protein ligase T (488 aa)
initn: 228 init1: 146 opt: 320 Z-score: 280.8 bits: 61.1 E(85289): 6.7e-09
Smith-Waterman score: 320; 24.0% identity (56.1% similar) in 287 aa overlap (1-281:20-288)
10 20 30 40
pF1KB9 MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGS
.: :. . .: .: . .: .. :.::::: :. :
NP_742 MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL
10 20 30 40 50 60
50 60 70 80 90
pF1KB9 VRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIK-ISPKM---PVCKGH
:. : ::.::: . ::. : .: ..:: .... .. :. .: :
NP_742 ERD-------FPCPVCRKTSR---YRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQH
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 LGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDA
. :..:: :.. .: ::: : :. ..:: . .. ... .. .: .. .
NP_742 -HEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLE--QKLQE
120 130 140 150 160
160 170 180 190 200 210
pF1KB9 LSRLDTLETSKRKSLQLLTKDS-DKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYD
..: . : .: :. :... ... . ::.:.. ::.... .:: .: . ..:
NP_742 ITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLR
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB9 PEINKLNTILQEQRMAFNIAEAF-KDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPAS
. .:. ... .: ::. : .. . .:.... :: . .: . ..
NP_742 ENAAHLGD--KRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIE--
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB9 PLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMF
: :::
NP_742 -LEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDT
290 300 310 320 330 340
407 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:25:37 2016 done: Sat Nov 5 08:25:39 2016
Total Scan time: 8.260 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]