Result of FASTA (omim) for
pF1KB9626
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9626, 135 aa
1>>>pF1KB9626 135 - 135 aa - 135 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5300+/-0.000264; mu= 11.6208+/- 0.017
mean_var=90.6052+/-18.933, 0's: 0 Z-trim(122.0): 104 B-trim: 2081 in 1/52
Lambda= 0.134740
statistics sampled from 39255 (39416) to 39255 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.462), width: 16
Scan time: 4.830
The best scores are: opt bits E(85289)
NP_005590 (OMIM: 162361) helix-loop-helix protein ( 135) 878 179.2 1.7e-45
NP_001104531 (OMIM: 162361) helix-loop-helix prote ( 135) 878 179.2 1.7e-45
NP_005589 (OMIM: 162360) helix-loop-helix protein ( 133) 487 103.2 1.3e-22
NP_005089 (OMIM: 603628) musculin [Homo sapiens] ( 206) 209 49.4 3.3e-06
NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172) 202 47.9 7.4e-06
XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172) 202 47.9 7.4e-06
NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331) 202 48.2 1.2e-05
XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 202 48.2 1.2e-05
XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 202 48.2 1.2e-05
XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 202 48.2 1.2e-05
XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 202 48.2 1.2e-05
NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331) 202 48.2 1.2e-05
NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331) 202 48.2 1.2e-05
NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331) 202 48.2 1.2e-05
NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331) 202 48.2 1.2e-05
XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 202 48.2 1.2e-05
XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 202 48.2 1.2e-05
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206) 198 47.2 1.5e-05
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108) 194 46.2 1.5e-05
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280) 198 47.3 1.8e-05
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302) 198 47.4 1.9e-05
XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351) 198 47.4 2.2e-05
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201) 189 45.5 4.8e-05
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201) 189 45.5 4.8e-05
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328) 186 45.1 0.0001
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199) 183 44.3 0.00011
XP_005268588 (OMIM: 602406) PREDICTED: heart- and ( 214) 180 43.7 0.00017
NP_004812 (OMIM: 602406) heart- and neural crest d ( 215) 180 43.7 0.00017
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217) 175 42.8 0.00034
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202) 174 42.5 0.00036
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202) 174 42.5 0.00036
XP_005264216 (OMIM: 609635) PREDICTED: transcripti ( 210) 172 42.2 0.00049
NP_786951 (OMIM: 609635) transcription factor 23 [ ( 214) 172 42.2 0.0005
NP_067014 (OMIM: 611635) neurogenic differentiatio ( 331) 174 42.7 0.00053
NP_003197 (OMIM: 603306) transcription factor 21 [ ( 179) 169 41.5 0.00065
NP_938206 (OMIM: 603306) transcription factor 21 [ ( 179) 169 41.5 0.00065
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 168 41.3 0.00069
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 168 41.3 0.00069
NP_002491 (OMIM: 125853,601724,606394) neurogenic ( 356) 172 42.4 0.00073
NP_066279 (OMIM: 604882,610370) neurogenin-3 [Homo ( 214) 165 40.8 0.0013
XP_016871769 (OMIM: 604882,610370) PREDICTED: neur ( 214) 165 40.8 0.0013
NP_660161 (OMIM: 609875) protein atonal homolog 7 ( 152) 161 39.9 0.0017
NP_073565 (OMIM: 611513) neurogenic differentiatio ( 337) 162 40.4 0.0027
NP_005163 (OMIM: 601461) protein atonal homolog 1 ( 354) 160 40.0 0.0036
NP_006151 (OMIM: 601725) neurogenic differentiatio ( 382) 159 39.9 0.0044
NP_061140 (OMIM: 608689) mesoderm posterior protei ( 268) 156 39.1 0.0051
NP_005161 (OMIM: 601886) achaete-scute homolog 2 [ ( 193) 154 38.6 0.0052
NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189) 152 38.2 0.0067
>>NP_005590 (OMIM: 162361) helix-loop-helix protein 2 [H (135 aa)
initn: 878 init1: 878 opt: 878 Z-score: 937.7 bits: 179.2 E(85289): 1.7e-45
Smith-Waterman score: 878; 100.0% identity (100.0% similar) in 135 aa overlap (1-135:1-135)
10 20 30 40 50 60
pF1KB9 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR
70 80 90 100 110 120
130
pF1KB9 LAICYISYLNHVLDV
:::::::::::::::
NP_005 LAICYISYLNHVLDV
130
>>NP_001104531 (OMIM: 162361) helix-loop-helix protein 2 (135 aa)
initn: 878 init1: 878 opt: 878 Z-score: 937.7 bits: 179.2 E(85289): 1.7e-45
Smith-Waterman score: 878; 100.0% identity (100.0% similar) in 135 aa overlap (1-135:1-135)
10 20 30 40 50 60
pF1KB9 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR
70 80 90 100 110 120
130
pF1KB9 LAICYISYLNHVLDV
:::::::::::::::
NP_001 LAICYISYLNHVLDV
130
>>NP_005589 (OMIM: 162360) helix-loop-helix protein 1 [H (133 aa)
initn: 478 init1: 461 opt: 487 Z-score: 527.0 bits: 103.2 E(85289): 1.3e-22
Smith-Waterman score: 487; 64.3% identity (75.5% similar) in 143 aa overlap (1-135:1-133)
10 20 30 40 50 60
pF1KB9 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHP
:::. : . . : : . ::. :: : .: :... : .. : : :. : :.:
NP_005 MMLNSD-TMELDLPPT-HSETES-GFSDCG--GGAG---P--DGAGPGGPGGGQARGPEP
10 20 30 40 50
70 80 90 100 110
pF1KB9 --------QQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKK
:.:::::.:::::::::::.::::::::::::::::::::::::::::::::
NP_005 GEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKK
60 70 80 90 100 110
120 130
pF1KB9 LSKIEILRLAICYISYLNHVLDV
:::::::::::::::::::::::
NP_005 LSKIEILRLAICYISYLNHVLDV
120 130
>>NP_005089 (OMIM: 603628) musculin [Homo sapiens] (206 aa)
initn: 182 init1: 154 opt: 209 Z-score: 232.4 bits: 49.4 E(85289): 3.3e-06
Smith-Waterman score: 209; 34.6% identity (62.4% similar) in 133 aa overlap (8-133:39-163)
10 20 30
pF1KB9 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSD
:. ::. :. . ::. : . .::....
NP_005 PEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPD--GEEERCALGTAGS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 LEPVEE-----AEGDGKGGSRAA--LYPHPQQLSREEKRRRRRATAKYRSAHATRERIRV
: .. : : : ::: .. : : . : : .. .: .:. .::: :.
NP_005 AEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAAN------ARERARM
70 80 90 100 110 120
100 110 120 130
pF1KB9 EAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
.... ::..:. :: .::: ::::.. :::: ::..: ..:
NP_005 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW
130 140 150 160 170 180
NP_005 PFVVSGRPDSDTKEVSAANRLCGTTA
190 200
>>NP_001277335 (OMIM: 187040,613065) T-cell acute lympho (172 aa)
initn: 200 init1: 200 opt: 202 Z-score: 226.1 bits: 47.9 E(85289): 7.4e-06
Smith-Waterman score: 202; 64.7% identity (82.4% similar) in 51 aa overlap (84-134:35-85)
60 70 80 90 100 110
pF1KB9 AALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKL
.::: : . : ::::::::.:: ::::::
NP_001 NNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKL
10 20 30 40 50 60
120 130
pF1KB9 SKIEILRLAICYISYLNHVLDV
:: ::::::. ::..: ..:.
NP_001 SKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQD
70 80 90 100 110 120
>>XP_016857682 (OMIM: 187040,613065) PREDICTED: T-cell a (172 aa)
initn: 200 init1: 200 opt: 202 Z-score: 226.1 bits: 47.9 E(85289): 7.4e-06
Smith-Waterman score: 202; 64.7% identity (82.4% similar) in 51 aa overlap (84-134:35-85)
60 70 80 90 100 110
pF1KB9 AALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKL
.::: : . : ::::::::.:: ::::::
XP_016 NNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKL
10 20 30 40 50 60
120 130
pF1KB9 SKIEILRLAICYISYLNHVLDV
:: ::::::. ::..: ..:.
XP_016 SKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGKDPVVGAGGGGGGGGGGAPPDDLLQD
70 80 90 100 110 120
>>NP_001274276 (OMIM: 187040,613065) T-cell acute lympho (331 aa)
initn: 200 init1: 200 opt: 202 Z-score: 222.3 bits: 48.2 E(85289): 1.2e-05
Smith-Waterman score: 203; 34.6% identity (57.4% similar) in 136 aa overlap (1-134:119-244)
10 20
pF1KB9 MMLSPDQAADSDHPSSA--HSDPESLGGTD
..::: : :. : .: . :..
NP_001 PTTELCRPPGPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLG
90 100 110 120 130 140
30 40 50 60 70 80
pF1KB9 TKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERI
. .: : :. . ..:. : : .. . . . . . . .:::
NP_001 SGFFGE-PDAFPMFTT------NNRVKRRPSPYEMEITDGPHTKVVRRIFTN---SRERW
150 160 170 180 190
90 100 110 120 130
pF1KB9 RVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
: . : ::::::::.:: :::::::: ::::::. ::..: ..:.
NP_001 RQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGK
200 210 220 230 240 250
NP_001 DPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLH
260 270 280 290 300 310
>>XP_016857677 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa)
initn: 200 init1: 200 opt: 202 Z-score: 222.3 bits: 48.2 E(85289): 1.2e-05
Smith-Waterman score: 203; 34.6% identity (57.4% similar) in 136 aa overlap (1-134:119-244)
10 20
pF1KB9 MMLSPDQAADSDHPSSA--HSDPESLGGTD
..::: : :. : .: . :..
XP_016 PTTELCRPPGPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLG
90 100 110 120 130 140
30 40 50 60 70 80
pF1KB9 TKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERI
. .: : :. . ..:. : : .. . . . . . . .:::
XP_016 SGFFGE-PDAFPMFTT------NNRVKRRPSPYEMEITDGPHTKVVRRIFTN---SRERW
150 160 170 180 190
90 100 110 120 130
pF1KB9 RVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
: . : ::::::::.:: :::::::: ::::::. ::..: ..:.
XP_016 RQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGK
200 210 220 230 240 250
XP_016 DPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLH
260 270 280 290 300 310
>>XP_016857676 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa)
initn: 200 init1: 200 opt: 202 Z-score: 222.3 bits: 48.2 E(85289): 1.2e-05
Smith-Waterman score: 203; 34.6% identity (57.4% similar) in 136 aa overlap (1-134:119-244)
10 20
pF1KB9 MMLSPDQAADSDHPSSA--HSDPESLGGTD
..::: : :. : .: . :..
XP_016 PTTELCRPPGPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLG
90 100 110 120 130 140
30 40 50 60 70 80
pF1KB9 TKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERI
. .: : :. . ..:. : : .. . . . . . . .:::
XP_016 SGFFGE-PDAFPMFTT------NNRVKRRPSPYEMEITDGPHTKVVRRIFTN---SRERW
150 160 170 180 190
90 100 110 120 130
pF1KB9 RVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
: . : ::::::::.:: :::::::: ::::::. ::..: ..:.
XP_016 RQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGK
200 210 220 230 240 250
XP_016 DPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLH
260 270 280 290 300 310
>>XP_016857680 (OMIM: 187040,613065) PREDICTED: T-cell a (331 aa)
initn: 200 init1: 200 opt: 202 Z-score: 222.3 bits: 48.2 E(85289): 1.2e-05
Smith-Waterman score: 203; 34.6% identity (57.4% similar) in 136 aa overlap (1-134:119-244)
10 20
pF1KB9 MMLSPDQAADSDHPSSA--HSDPESLGGTD
..::: : :. : .: . :..
XP_016 PTTELCRPPGPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLG
90 100 110 120 130 140
30 40 50 60 70 80
pF1KB9 TKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERI
. .: : :. . ..:. : : .. . . . . . . .:::
XP_016 SGFFGE-PDAFPMFTT------NNRVKRRPSPYEMEITDGPHTKVVRRIFTN---SRERW
150 160 170 180 190
90 100 110 120 130
pF1KB9 RVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
: . : ::::::::.:: :::::::: ::::::. ::..: ..:.
XP_016 RQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKTGK
200 210 220 230 240 250
XP_016 DPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARSLH
260 270 280 290 300 310
135 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:15:42 2016 done: Sat Nov 5 20:15:43 2016
Total Scan time: 4.830 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]