Result of FASTA (omim) for
pF1KB9598
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9598, 478 aa
1>>>pF1KB9598 478 - 478 aa - 478 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5893+/-0.000393; mu= 1.5717+/- 0.025
mean_var=343.5209+/-70.586, 0's: 0 Z-trim(123.4): 132 B-trim: 35 in 1/57
Lambda= 0.069199
statistics sampled from 42929 (43069) to 42929 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.505), width: 16
Scan time: 11.290
The best scores are: opt bits E(85289)
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 3213 334.3 4.5e-91
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 882 101.6 4.9e-21
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 843 97.7 7.7e-20
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 707 84.0 7.8e-16
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 700 83.4 1.3e-15
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 685 81.9 3.8e-15
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 683 81.7 4.4e-15
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 674 80.8 8.5e-15
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 620 75.5 3.9e-13
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 586 71.9 3e-12
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 575 70.9 8.1e-12
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 564 69.7 1.5e-11
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 560 69.5 2.6e-11
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 556 69.1 3.2e-11
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 548 68.2 5.3e-11
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 548 68.2 5.4e-11
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 537 67.1 1.1e-10
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 526 66.0 2.2e-10
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 523 65.6 2.5e-10
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 517 65.1 4.2e-10
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 514 64.7 4.5e-10
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 508 64.1 7e-10
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 492 62.6 2.3e-09
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 489 62.3 3.1e-09
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 489 62.4 3.2e-09
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 407 54.1 8.7e-07
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 398 53.4 2.2e-06
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 376 51.2 9.1e-06
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 376 51.3 1.1e-05
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 367 50.3 1.7e-05
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 367 50.3 1.7e-05
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 367 50.3 1.7e-05
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 361 49.7 2.7e-05
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 361 49.7 2.7e-05
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 361 49.7 2.7e-05
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 361 49.7 2.7e-05
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 361 49.7 2.7e-05
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 361 49.7 2.7e-05
NP_001278210 (OMIM: 611457) forkhead box protein O ( 559) 335 47.1 0.00015
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 317 44.9 0.00034
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 309 44.3 0.0007
XP_011519236 (OMIM: 602341) PREDICTED: forkhead bo ( 433) 299 43.4 0.0016
NP_001230018 (OMIM: 602341) forkhead box protein M ( 747) 287 42.4 0.0052
NP_973732 (OMIM: 602341) forkhead box protein M1 i ( 748) 287 42.4 0.0052
NP_001230017 (OMIM: 602341) forkhead box protein M ( 748) 286 42.3 0.0055
XP_011519233 (OMIM: 602341) PREDICTED: forkhead bo ( 749) 286 42.3 0.0055
XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 279 41.4 0.0062
NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 279 41.4 0.0062
XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 279 41.4 0.0062
XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 279 41.4 0.0062
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 3213 init1: 3213 opt: 3213 Z-score: 1756.1 bits: 334.3 E(85289): 4.5e-91
Smith-Waterman score: 3213; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478)
10 20 30 40 50 60
pF1KB9 MTLSGGGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MTLSGGGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYRE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QQEHLREQTALMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QQEHLREQTALMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 LQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 AGTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AGTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLRPP
370 380 390 400 410 420
430 440 450 460 470
pF1KB9 GTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
430 440 450 460 470
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 766 init1: 766 opt: 882 Z-score: 498.6 bits: 101.6 E(85289): 4.9e-21
Smith-Waterman score: 1047; 45.7% identity (61.1% similar) in 486 aa overlap (1-447:1-446)
10 20 30 40 50
pF1KB9 MTLSGGGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGP----PELRLD
:::: :: :: ::..::::::::.: .:.. : . .:: : :
NP_004 MTLS--TEMSDASG----LAEETDIDVVGEGEDEEDEEEEDDDEGGGGGPRLAVPAQRRR
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 EADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGAS
. . . .. . : :.:. : :: :: : . :: :: ::..
NP_004 RRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPPG---PAPAAGAGAGGGGG--GGGA
60 70 80 90 100
120 130 140 150 160 170
pF1KB9 GGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFP
::: .::::. :: ::::::::::::::::::::.:.:::: ::::::.:::
NP_004 GGGGSAGSGA---------KNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB9 YYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKR
:::::::::::::::::::::::::::::::::::::::::::.: ::::::::::::::
NP_004 YYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKR
170 180 190 200 210 220
240 250 260 270
pF1KB9 FKRHQ--QEHLREQTALMMQSFGAYSLAA--AAGAA---------------GPYGRPYGL
:::. . .:.... :: . :. ::.:: :::: :::
NP_004 FKRQPLLPPNAAAAESLLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGL
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB9 HPAAAAGAYSHPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQL
. : . :::::::::::. .:.. :: :: : ..::.: .::: .
NP_004 QLPPYAPPSALFAAAAAAAAAAAF-HPHS-PP-----PPPPPHGAAAELAR--TAFGYRP
290 300 310 320 330
340 350 360 370 380 390
pF1KB9 GP-GLQLQLNSLGAAAAAAGTAGAAGTTASLIKSEPSARPSFSIENIIGG--GPAAPGGS
: : : . : :.:: :: ::.. :: ::::.:::: :::: ...
NP_004 HPLGAALP-GPLPASAAKAGGPGASAL----------ARSPFSIESIIGGSLGPAAAAAA
340 350 360 370 380
400 410 420 430 440
pF1KB9 AVGAGVAG-------------GTGGSGGGSTAQSFLRPPGTVQSAALMATHQPLSLSRTT
:. :..:. . :.:::: .::. . : ... . . :. : ..
NP_004 AAQAAAAAQASPSPSPVAAPPAPGSSGGGCAAQAAVGPAAALTRSLVAAAAAAASSVSSS
390 400 410 420 430 440
450 460 470
pF1KB9 ATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
:... .
NP_004 AALGTLHQGTALSSVENFTARISNC
450 460
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 913 init1: 740 opt: 843 Z-score: 477.2 bits: 97.7 E(85289): 7.7e-20
Smith-Waterman score: 975; 42.7% identity (57.5% similar) in 485 aa overlap (10-434:12-472)
10 20 30 40 50
pF1KB9 MTLSGGGSASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEA
:. :. ..:. :.:::::: :. : : . .:: :
NP_004 MTLGSCCCEIMSSESSPAALSEADADIDVVGGGSGGGE-------LPARSGPRAPR----
10 20 30 40
60 70 80 90 100 110
pF1KB9 DEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDV------GAPEADGCKGGVGGEE
: .: ::. : .. : .. .:. :. :: : : : ..
NP_004 DVLP-----HGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB9 GGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFIS
::.: ::: ::.:. .: ::::::::::::::::::::.:.:::: ::::::
NP_004 RGAAGPGPGPPSGGAATRSP------LVKPPYSYIALITMAILQSPKKRLTLSEICEFIS
110 120 130 140 150
180 190 200 210 220 230
pF1KB9 NRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLR
.::::::::::::::::::::::::::::::::::::::::::::::.: ::::::::::
NP_004 GRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLR
160 170 180 190 200 210
240 250 260 270
pF1KB9 RRKRFKRHQ----QEHLREQTALMMQSFGAYSLAAAA-----GAAGPYGRPYGLH-----
:::::::. . : . . :.... .: . .: .: : :: :::
NP_004 RRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYG
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB9 ---PAAAAGAYSHPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPS-----GELGRKA
:. : . :: : : :::::: ..:: . :: : : : :
NP_004 APPPGPAPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPA
280 290 300 310 320 330
340 350 360 370
pF1KB9 AAFGSQLGPG-------LQLQLNSLGAAAAAAGTAGAAGTTASL--------IKSEPSA-
: :: ::: : .:. : ::. . ::::.:.: .:.. ..
NP_004 PASGSGPGPGPAGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDAGGG
340 350 360 370 380 390
380 390 400 410
pF1KB9 ----------RPSFSIENIIG--GGPAAPGGSAVGAGVAG----GTGGSGGGSTAQSFLR
::::::..:.: :: ::: :. : : : ...: :: . . ..:
NP_004 AGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGA--GEGSPGPPFAAAAGPGGQAQVLAMLT
400 410 420 430 440 450
420 430 440 450 460 470
pF1KB9 PPGTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
:. . :. . .:
NP_004 APALAPVAGHIRLSHPGDALLSSGSRFASKVAGLSGCHF
460 470 480 490
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 687 init1: 574 opt: 707 Z-score: 405.3 bits: 84.0 E(85289): 7.8e-16
Smith-Waterman score: 712; 44.1% identity (63.2% similar) in 345 aa overlap (112-434:24-342)
90 100 110 120 130 140
pF1KB9 PKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSG-SAGGLAPSKPKNSLV
: .:..: :: ..: .::: ..: .
NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRG-
10 20 30 40 50
150 160 170 180 190 200
pF1KB9 KPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFV
::::::::::.::: ..:...:::.:: .::..:::.::.. :::::::::.:::::.
NP_004 KPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFL
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB9 KIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALMMQSFGAYS
::::: : :::::::.:::..::::..:::::::::::: . : : : .. .: .
NP_004 KIPREAGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSD---LSTYPAYMHDAAAAAA
120 130 140 150 160
270 280 290 300 310
pF1KB9 LAAAAGAAG-------PYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYPYALPPVAPV
::::.::. : .:: .:.:. ..:. :. :: . :: : : :
NP_004 AAAAAAAAAAIFPGAVPAARPP--YPGAVYAGYAPPSLAA----PPPVYYPAASPGPCRV
170 180 190 200 210 220
320 330 340 350 360 370
pF1KB9 --LPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASLIKSE
: : :: : ::: . ::: . . : :: :...: :. : : .
NP_004 FGLVPERPLSP--ELGPAPS------GPGGSCAFASAGAPATTTGYQPAGCTGA-----R
230 240 250 260 270
380 390 400 410
pF1KB9 PSARPSFSIENIIGGGPAAP--GGSAV--GAGVAGG-----TGGSGGG--STAQSFLRP-
: : :: : : : .:::. .:: .: .:::.:: .:.. . :
NP_004 P-ANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTS
280 290 300 310 320
420 430 440 450 460 470
pF1KB9 PGTVQSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
:: : .:: : ..:
NP_004 PG--QFGALGACYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM
330 340 350 360 370
>>NP_036316 (OMIM: 611084) forkhead box protein D4-like (408 aa)
initn: 754 init1: 660 opt: 700 Z-score: 401.1 bits: 83.4 E(85289): 1.3e-15
Smith-Waterman score: 750; 45.2% identity (62.5% similar) in 347 aa overlap (106-410:65-405)
80 90 100 110 120 130
pF1KB9 QQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGS--GSAGGLAP-
:::. . ::::. : :. :
NP_036 DEDEVEDEEEEASQKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPR
40 50 60 70 80 90
140 150 160 170 180
pF1KB9 ----SKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNS
:. . .::::::::::::::::::.:.::::::: :::.::::::.::::::::
NP_036 SAAASEDARQPAKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQE---HL
:::::::::::::::::::.::::.::.::: :.::::::::::::::::::: ::
NP_036 IRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHL
160 170 180 190 200 210
250 260 270 280
pF1KB9 RE-------QTALMMQS----FGAYSLAAAAGAA----GPYGRPYGL-HPAAAAGAY-SH
. ..:: .:: .: . .: .: :::.: :: :
NP_036 PHPFPLPAAHAALHNPRPGPLLGAPALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSA
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB9 PAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPG-LQLQLNS
:: :.: : . . : : . ::: :.. : : :. ...: : : ......:
NP_036 PAYAGAPKKAEGAD--LATPGTLPVLQPSLGPQP-WEEGK---GLASPPGGGCISFSIES
280 290 300 310 320
350 360 370 380 390
pF1KB9 LGAAAAAAGTAGAAGTTASLIKSEPS-ARPSFSIENIIGGGPAAPGG--------SAVGA
. .. .:::..: . . . . : ::: .:. . . :. :: .. ::
NP_036 IMQGVRGAGTGAAQSLSPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGA
330 340 350 360 370 380
400 410 420 430 440 450
pF1KB9 GVA-----GGTGGSGGGSTAQSFLRPPGTVQSAALMATHQPLSLSRTTATIAPILSVPLS
: : :... ::::
NP_036 GRAPVGRVGAAAVSGGGRGL
390 400
>>NP_954586 (OMIM: 611086) forkhead box protein D4-like (417 aa)
initn: 734 init1: 666 opt: 685 Z-score: 392.9 bits: 81.9 E(85289): 3.8e-15
Smith-Waterman score: 700; 48.5% identity (61.2% similar) in 299 aa overlap (38-314:18-303)
10 20 30 40 50 60
pF1KB9 SASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPH
.::: : : : .. .: :: .
NP_954 MNLPRAERLRSTPQRSLRDSD-GED---GKIDVLGEEEDEDEVEDEE
10 20 30 40
70 80 90 100 110 120
pF1KB9 HGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSA
.. : .: : : : .. : :. :. . .:: : . . : : ::
NP_954 EAASQQFLEQSLQ-P----GLQVARWGGVALPR-EHIEGGGGPSDPSEFGTKFRAPPRSA
50 60 70 80 90
130 140 150 160 170 180
pF1KB9 GGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQN
: :. . .::::::::::::::::.:.:.::::::: :::.::::::.:::::::
NP_954 ---AASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQE---H
::::::::::::::::::::.:::::::.::: :.::::::::::::::::::: :
NP_954 SIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAH
160 170 180 190 200 210
250 260 270 280
pF1KB9 LRE-------QTALMMQSFGAYSLAAAA-----GA---AGPYGRPYGL-HPAAAAGAY-S
: . ..:: : : : :: ..: :::.: :: :
NP_954 LPHPFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB9 HPAAAAAA--AAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQL
:. :.: : .::: : .: .: :
NP_954 APVYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGS
280 290 300 310 320 330
>>NP_954714 (OMIM: 611085) forkhead box protein D4-like (416 aa)
initn: 724 init1: 666 opt: 683 Z-score: 391.8 bits: 81.7 E(85289): 4.4e-15
Smith-Waterman score: 693; 54.7% identity (64.9% similar) in 225 aa overlap (106-322:65-265)
80 90 100 110 120 130
pF1KB9 QQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVG-GEEGGASGGGPGAGS--GSAGGLAP
:::. .: .::::. : :. :
NP_954 DEDEVEDEEEEARQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPP
40 50 60 70 80 90
140 150 160 170 180
pF1KB9 -----SKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQN
:. . .::::::::::::::::.:.:.::::::: :::.::::::.:::::::
NP_954 RSAAASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLRE
::::::::::::::::::::.:::::::.::: :.:::::::::::::::::::
NP_954 SIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQL-----
160 170 180 190 200
250 260 270 280 290 300
pF1KB9 QTALMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYPYAL
. :: :. :. : : :: ::. .: : : :
NP_954 ----------------TPGAHLPH--PFPLPAAHAALHNPHPGPLLGAPAPPQ-PVPGAY
210 220 230 240 250
310 320 330 340 350 360
pF1KB9 PPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASL
: .:: : . : :
NP_954 PNTAPGRRPYALLHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRR
260 270 280 290 300 310
>>NP_997188 (OMIM: 601092) forkhead box protein D4 [Homo (439 aa)
initn: 725 init1: 656 opt: 674 Z-score: 386.6 bits: 80.8 E(85289): 8.5e-15
Smith-Waterman score: 695; 54.8% identity (64.9% similar) in 239 aa overlap (106-314:61-299)
80 90 100 110 120 130
pF1KB9 QQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVG-GEEGGASGGGPGAGS--GSAGGLAP
:::. .: .::::. : :. :
NP_997 GEEEDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPP
40 50 60 70 80 90
140 150 160 170 180
pF1KB9 -----SKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQN
:. . .::: ::::::::::::::.:.::::::: :::.::::::.:::::::
NP_997 RSAAASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 SIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQE---H
:::::::::::::::::::: :::::::.::: :.:::::::::::::::.::: :
NP_997 SIRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAH
160 170 180 190 200 210
250 260 270 280
pF1KB9 LRE-------QTALMMQSFGAYSLAAAA-----GA---AGPYGRPYGL-HPAAAAGAY-S
: . ..:: : : : :: .:: :::.: :: :
NP_997 LPHPFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLS
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB9 HPAAAAAA--AAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQL
:: :.: : .: : : .: .: :
NP_997 APAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGS
280 290 300 310 320 330
>>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa)
initn: 633 init1: 546 opt: 620 Z-score: 356.8 bits: 75.5 E(85289): 3.9e-13
Smith-Waterman score: 636; 41.1% identity (60.5% similar) in 309 aa overlap (101-402:27-295)
80 90 100 110 120 130
pF1KB9 PQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSAGGL
: : ::... : :: ..: . .
NP_005 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSY
10 20 30 40 50
140 150 160 170 180
pF1KB9 AP------SKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPA
:: . ::. :::::::::::::::: ..:.::.::.:: .:: .:::.:::. .
NP_005 APYHHHQPAAPKD-LVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQG
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB9 WQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEH
::::::::::::.::::.::. .::::.::::::.: .::.::::::::.:::... .
NP_005 WQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSK
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB9 LREQTALMMQSFGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAAAALQYP
.:. : . . : : :::. :: ::. : : .
NP_005 EKEERAHLKE---------------P---P----PAASKGA---PATPHLADAPKEAEKK
180 190 200 210
310 320 330 340 350 360
pF1KB9 YALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTT
.. : ::.:.. . : :.: :: . .::.. ::. :.
NP_005 VVIKSEAA--SPALPVITKVET----------LSPESALQGSPRSAASTPAGSPD--GSL
220 230 240 250
370 380 390 400 410 420
pF1KB9 ASLIKSEPSARPSFSIENIIGGGPAAPGGS-AVGAGVAGGTGGSGGGSTAQSFLRPPGTV
. :.. :.::.:::. . ::: . ::: ::
NP_005 PEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQP
260 270 280 290 300 310
430 440 450 460 470
pF1KB9 QSAALMATHQPLSLSRTTATIAPILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
NP_005 CAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAA
320 330 340 350 360 370
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 612 init1: 537 opt: 586 Z-score: 340.8 bits: 71.9 E(85289): 3e-12
Smith-Waterman score: 614; 42.3% identity (56.1% similar) in 319 aa overlap (58-356:5-297)
30 40 50 60 70 80
pF1KB9 VGEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAG
.: :::: : : : : . : .
NP_036 MAGRSDMDPPAA-FSGFPALPAVAP-SGPPPSPL
10 20 30
90 100 110 120 130 140
pF1KB9 AGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSAG-GLAPSKPKNSLVKPPYSY
::: :: . :: .:.: : .: . . : : .: . ::::::
NP_036 AGAEPGRE---PEE------------AAAGRGEAAPTPAPGPGRRRRRPLQRG-KPPYSY
40 50 60 70
150 160 170 180 190 200
pF1KB9 IALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREP
::::.::. ..: ..:::..: .::..:: .::.. :::::::::.:::::::.::::
NP_036 IALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREP
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB9 GNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALMMQSFGAYSLAAAAG
::::::::::::: . ::::::::::::::::: . . : : : :
NP_036 GNPGKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPG
140 150 160 170 180 190
270 280 290 300
pF1KB9 --------AAGPYGRP----------YGLHPAAAA-GAYSHPAAAAAAAAAAALQYPYAL
.::: : .:.: :. :: : :: ::::: .:
NP_036 PALLVPPPSAGPGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAA--FP---
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB9 PPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASL
: .: . :: .:. .: :. : :: : .:.. ::: :
NP_036 PCAAAASPPLYSQVPD-RLVLPATRPGP--GPLPAEPLLALAGPAAALGPLSPGEAYLRQ
260 270 280 290 300
370 380 390 400 410 420
pF1KB9 IKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLRPPGTVQSAA
NP_036 PGFASGLERYL
310
478 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:34:55 2016 done: Fri Nov 4 17:34:57 2016
Total Scan time: 11.290 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]