Result of FASTA (omim) for
pF1KB9594
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9594, 325 aa
1>>>pF1KB9594 325 - 325 aa - 325 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.7016+/-0.000363; mu= -8.5486+/- 0.023
mean_var=277.5932+/-56.820, 0's: 0 Z-trim(122.8): 132 B-trim: 44 in 2/58
Lambda= 0.076979
statistics sampled from 41436 (41570) to 41436 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.487), width: 16
Scan time: 8.470
The best scores are: opt bits E(85289)
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 608 80.2 8.9e-15
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 608 80.2 9e-15
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 588 78.0 3.3e-14
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 583 77.5 6.2e-14
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 571 76.1 1.2e-13
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 561 75.0 3.4e-13
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 558 74.7 4e-13
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 558 74.7 4.3e-13
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 551 73.9 7.6e-13
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 532 71.8 2.6e-12
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 524 70.9 5.3e-12
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 524 70.9 5.3e-12
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 517 70.1 9.4e-12
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 515 69.9 1.2e-11
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 506 68.8 1.8e-11
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 507 69.0 1.9e-11
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 498 67.9 3.1e-11
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 503 68.6 3.4e-11
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 459 63.6 7.2e-10
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 459 63.7 8.3e-10
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 452 62.9 1.4e-09
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 446 62.2 2e-09
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 444 62.0 2.3e-09
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 444 62.0 2.8e-09
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 391 56.1 1.4e-07
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 388 55.9 2.4e-07
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 388 55.9 3e-07
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 379 54.9 4.8e-07
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 379 54.9 4.9e-07
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 379 54.9 5e-07
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 375 54.3 5.1e-07
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 374 54.3 7.4e-07
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 374 54.3 7.6e-07
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 374 54.3 7.6e-07
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 374 54.3 7.6e-07
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 374 54.3 7.6e-07
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 374 54.3 7.7e-07
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 363 53.1 1.9e-06
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 308 46.8 6.4e-05
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 300 46.0 0.00015
NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 294 45.4 0.00028
NP_001078940 (OMIM: 602628) forkhead box protein N ( 490) 294 45.4 0.00029
XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 290 44.9 0.00036
XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 290 44.9 0.00036
NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 290 44.9 0.00036
XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 290 44.9 0.00036
XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 290 44.9 0.00036
XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 290 44.9 0.00036
XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 290 44.9 0.00036
XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 290 44.9 0.00036
>>NP_710141 (OMIM: 600288) hepatocyte nuclear factor 3-b (457 aa)
initn: 591 init1: 563 opt: 608 Z-score: 386.3 bits: 80.2 E(85289): 8.9e-15
Smith-Waterman score: 628; 47.6% identity (67.1% similar) in 225 aa overlap (2-220:148-357)
10 20 30
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPE
:. : .:. ::::::::: .::::.::.
NP_710 AGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPN
120 130 140 150 160 170
40 50 60 70 80 90
pF1KB9 KMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHP
::: :::::..::: ::.::.: ::::::.::.:::::::.:.:: ::.:::::::.:::
NP_710 KMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHP
180 190 200 210 220 230
100 110 120 130 140 150
pF1KB9 SCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAASGTHLPQMP
. :.::::: .:::.:::: : .:: .. : :: .. : :.. . :.
NP_710 DSGNMFENGCYLRRQKRFKCEK--QLALKEAAGAAGSGKKAA-------AGAQASQAQLG
240 250 260 270 280
160 170 180 190 200
pF1KB9 AAAYNLGGVAQ-PSGFKHPFAIENIIAREYKMPG-----GLAFSAMQPVPAAYPLPNQLT
:: : ... :.: . : . . .:.: : : .:..: : : :.:
NP_710 EAA---GPASETPAGTESPHSSASP-CQEHKRGGLGELKGTPAAALSP-PEPAPSPGQQQ
290 300 310 320 330 340
210 220 230 240 250 260
pF1KB9 TMGSSLGTGWPHVYGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVPIKP
.. : : :: :
NP_710 QAAAHL-LGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDL
350 360 370 380 390 400
>>NP_068556 (OMIM: 600288) hepatocyte nuclear factor 3-b (463 aa)
initn: 591 init1: 563 opt: 608 Z-score: 386.2 bits: 80.2 E(85289): 9e-15
Smith-Waterman score: 628; 47.6% identity (67.1% similar) in 225 aa overlap (2-220:154-363)
10 20 30
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPE
:. : .:. ::::::::: .::::.::.
NP_068 AGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPN
130 140 150 160 170 180
40 50 60 70 80 90
pF1KB9 KMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHP
::: :::::..::: ::.::.: ::::::.::.:::::::.:.:: ::.:::::::.:::
NP_068 KMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHP
190 200 210 220 230 240
100 110 120 130 140 150
pF1KB9 SCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAASGTHLPQMP
. :.::::: .:::.:::: : .:: .. : :: .. : :.. . :.
NP_068 DSGNMFENGCYLRRQKRFKCEK--QLALKEAAGAAGSGKKAA-------AGAQASQAQLG
250 260 270 280 290
160 170 180 190 200
pF1KB9 AAAYNLGGVAQ-PSGFKHPFAIENIIAREYKMPG-----GLAFSAMQPVPAAYPLPNQLT
:: : ... :.: . : . . .:.: : : .:..: : : :.:
NP_068 EAA---GPASETPAGTESPHSSASP-CQEHKRGGLGELKGTPAAALSP-PEPAPSPGQQQ
300 310 320 330 340
210 220 230 240 250 260
pF1KB9 TMGSSLGTGWPHVYGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVPIKP
.. : : :: :
NP_068 QAAAHL-LGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDL
350 360 370 380 390 400
>>NP_004488 (OMIM: 602295) hepatocyte nuclear factor 3-g (350 aa)
initn: 614 init1: 578 opt: 588 Z-score: 376.0 bits: 78.0 E(85289): 3.3e-14
Smith-Waterman score: 588; 57.1% identity (74.7% similar) in 154 aa overlap (1-154:105-257)
10 20 30
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSP
::. : . ::::::::: .::::..:
NP_004 GPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAP
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB9 EKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALH
::: :::::..::: ::::::: ::::::.::.:::::::.:. : ::.:::::.::::
NP_004 GKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALH
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB9 PSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAASGTHLPQM
:: :.::::: .:::.::::. .. . . : : ... .: . ::. : ::
NP_004 PSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAASTTTP-AATVTSPPQP
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB9 PAAAYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQPVPAAYPLPNQLTTMGSS
: :
NP_004 PPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQ
260 270 280 290 300 310
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 601 init1: 492 opt: 583 Z-score: 371.2 bits: 77.5 E(85289): 6.2e-14
Smith-Waterman score: 583; 38.4% identity (58.8% similar) in 323 aa overlap (13-323:125-433)
10 20 30 40
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKF
:::::::.: .::: .::.: : :::: .:
NP_004 AAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEF
100 110 120 130 140 150
50 60 70 80 90 100
pF1KB9 IMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSF
: :::::::. ::::.:::::.::::.::::.: .::::..:.: : .:::.::::
NP_004 ISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSF
160 170 180 190 200 210
110 120 130 140 150
pF1KB9 LRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSAL--AASGTHLPQMPAA---AYNL
:::::::: . : : . : : . : . : .: ::... .: : ::.
NP_004 LRRRKRFK---RQPLLPPNAAAAESLLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAYGY
220 230 240 250 260 270
160 170 180 190 200 210
pF1KB9 GGVAQPSGFK-HPFAIEN-IIAREYKMPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGW
: . :.. :.: . ..: .. :: .: : : :. .. . . :.
NP_004 GPYGCGYGLQLPPYAPPSALFAAAAAAAAAAAFHPHSPPPP--PPPHGAAAELARTAFGY
280 290 300 310 320
220 230 240 250 260 270
pF1KB9 -PHVYGSAGMIDSATPISMA-SGDYSAYGVPLKPLC--HAAGQTL-PAIPVPIKPTPAAV
:: :.: . . : : : .: .: .. .:. : .: :: . ::
NP_004 RPHPLGAA--LPGPLPASAAKAGGPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAA-
330 340 350 360 370 380
280 290 300 310 320
pF1KB9 PALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH
: : :.: :. .:: .: :: . . .. . :. .:: : ..:
NP_004 -AAQASPSPSPV---AAPP--APGSSGGGCAAQAAVGPAAALTRSLVAAAAAAASSVSSS
390 400 410 420 430 440
NP_004 AALGTLHQGTALSSVENFTARISNC
450 460
>>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa)
initn: 555 init1: 502 opt: 571 Z-score: 366.2 bits: 76.1 E(85289): 1.2e-13
Smith-Waterman score: 571; 38.4% identity (60.9% similar) in 302 aa overlap (1-289:6-298)
10 20 30 40 50
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQ
.: :: : :::::::.: :::::::: . :: ::..:: :: .::.:
NP_004 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 RWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSD
::::.:::::.:.::.:.:: .:::::.:.: :.: ::::.:::::::.:: . ..
NP_004 GWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRF-TRQTG
70 80 90 100 110
120 130 140 150 160
pF1KB9 HLAPSKPADAAQY-LQQQAKLRLSALAASGTHL---PQMP-AAAYNLGGV--AQPSGFKH
. :: : . :. .. :..: . :..: . ..::. :.:...
NP_004 AEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPASMC-
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 PFAIENIIAREYKMPGGLAFSAMQPV-PAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDS
: : . : : . :. .:. :. :. :. .: . :.: .. : ...
NP_004 P-ATTDGRPRPPMEPKEI--STPKPACPGELPVA---TSSSSCPAFGFPAGFSEAESFNK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB9 A-TPI-SMASGDYSAYGVPLKPL--CHAAGQTLPAIPVPIKPTPAAVPALP-ALPAPIPT
: ::. : :: :.: :. : : .: : . . :.:: :. : .: ::.:
NP_004 APTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAPSPAP-PTPPGSLRAPLPL
240 250 260 270 280 290
290 300 310 320
pF1KB9 LLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH
... :
NP_004 PTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE
300 310 320 330
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 571 init1: 498 opt: 561 Z-score: 357.8 bits: 75.0 E(85289): 3.4e-13
Smith-Waterman score: 568; 37.4% identity (59.0% similar) in 334 aa overlap (4-319:132-448)
10 20 30
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKM
:.. : :::::::.: .::: .::.:
NP_036 DGCKGGVGGEEGGASGGGPGAGSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKK
110 120 130 140 150 160
40 50 60 70 80 90
pF1KB9 LPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSC
: :: : .:: .:::::::. ::::.:::::.::::.::::.: .::::..:.: :.
NP_036 LTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQS
170 180 190 200 210 220
100 110 120 130 140 150
pF1KB9 GDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAASGTHLPQMPAA
:::.:::::::::::: ...:: . .: ..:. . :.: :.:. : .
NP_036 EDMFDNGSFLRRRKRFKRHQQEHLREQ----TALMMQSFGAYSLAA--AAGAAGPY--GR
230 240 250 260 270
160 170 180 190 200
pF1KB9 AYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQPV-PAAYPL-PN-----QLTT
:.: .: ....:: : : . :. . :: : : :: :. . ..
NP_036 PYGLHPAAAAGAYSHP-AAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAA
280 290 300 310 320 330
210 220 230 240 250 260
pF1KB9 MGSSLGTGWPHVYGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVPIKPT
.::.:: : .: : .:. . :.: .: . .: .: .. .: :
NP_036 FGSQLGPGLQLQLNSLGAAAAAAGTAGAAGT-TASLIKSEP---SARPSF-SIENIIGGG
340 350 360 370 380
270 280 290 300 310
pF1KB9 PAAVPALPALPAPIPTLLSNS-----------PPSLSPTSSQTATSQSSPATPSETLTSP
::: :. :. : . ..: ::. ... :: : : . :.: ..
NP_036 PAA-PGGSAVGAGVAGGTGGSGGGSTAQSFLRPPGTVQSAALMATHQ--PLSLSRTTATI
390 400 410 420 430 440
320
pF1KB9 ASALHSVAVH
: :
NP_036 APILSVPLSGQFLQPAASAAAAAAAAAQAKWPAQ
450 460 470
>>XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte nucl (439 aa)
initn: 598 init1: 558 opt: 558 Z-score: 356.6 bits: 74.7 E(85289): 4e-13
Smith-Waterman score: 579; 38.2% identity (58.6% similar) in 314 aa overlap (6-294:130-439)
10 20 30
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLP
. .: ::::::::: .::::..: :::
XP_016 AMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLT
100 110 120 130 140 150
40 50 60 70 80 90
pF1KB9 LSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGD
:::::..::: :::::.: ::::::.::.:::::::.:. : ::.:::::.:.:::. :.
XP_016 LSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGN
160 170 180 190 200 210
100 110 120 130 140
pF1KB9 MFENGSFLRRRKRFKVLKSDHLA----PSKPADAAQYLQQQAKLRLSALAAS-------G
::::: .:::.:::: :. . .. ...:. .. : .: : :
XP_016 MFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGASNPSADSPLHRG
220 230 240 250 260 270
150 160 170 180 190
pF1KB9 TH--LPQMPAAAYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAF-------SAMQPVP
.: :. .: : .:.:. . : : . : : : :.. . .:. ::
XP_016 VHGKTGQLEGAPAP-GPAASPQTLDHSGATATGGASELKTPASSTAPPISSGPGALASVP
280 290 300 310 320 330
200 210 220 230 240 250
pF1KB9 AAYPLPNQLTTMGSSLGT-GWPHV-YGSAGMIDSATPISMASG--DYSAYGVPLKPLCHA
:..: . :. :.: : :: .. :.. : . :..:: :.
XP_016 ASHP-AHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQALQ--YSP
340 350 360 370 380 390
260 270 280 290 300 310
pF1KB9 AGQTLPA-IPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSE
:.:::: .:. . . : :. : : : :. .
XP_016 YGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
400 410 420 430
320
pF1KB9 TLTSPASALHSVAVH
>>NP_004487 (OMIM: 602294) hepatocyte nuclear factor 3-a (472 aa)
initn: 598 init1: 558 opt: 558 Z-score: 356.1 bits: 74.7 E(85289): 4.3e-13
Smith-Waterman score: 579; 38.2% identity (58.6% similar) in 314 aa overlap (6-294:163-472)
10 20 30
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLP
. .: ::::::::: .::::..: :::
NP_004 AMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLT
140 150 160 170 180 190
40 50 60 70 80 90
pF1KB9 LSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGD
:::::..::: :::::.: ::::::.::.:::::::.:. : ::.:::::.:.:::. :.
NP_004 LSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGN
200 210 220 230 240 250
100 110 120 130 140
pF1KB9 MFENGSFLRRRKRFKVLKSDHLA----PSKPADAAQYLQQQAKLRLSALAAS-------G
::::: .:::.:::: :. . .. ...:. .. : .: : :
NP_004 MFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGASNPSADSPLHRG
260 270 280 290 300 310
150 160 170 180 190
pF1KB9 TH--LPQMPAAAYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAF-------SAMQPVP
.: :. .: : .:.:. . : : . : : : :.. . .:. ::
NP_004 VHGKTGQLEGAPAP-GPAASPQTLDHSGATATGGASELKTPASSTAPPISSGPGALASVP
320 330 340 350 360 370
200 210 220 230 240 250
pF1KB9 AAYPLPNQLTTMGSSLGT-GWPHV-YGSAGMIDSATPISMASG--DYSAYGVPLKPLCHA
:..: . :. :.: : :: .. :.. : . :..:: :.
NP_004 ASHP-AHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQALQ--YSP
380 390 400 410 420
260 270 280 290 300 310
pF1KB9 AGQTLPA-IPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSE
:.:::: .:. . . : :. : : : :. .
NP_004 YGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
430 440 450 460 470
320
pF1KB9 TLTSPASALHSVAVH
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 550 init1: 492 opt: 551 Z-score: 351.6 bits: 73.9 E(85289): 7.6e-13
Smith-Waterman score: 564; 40.4% identity (57.4% similar) in 312 aa overlap (2-299:115-379)
10 20 30
pF1KB9 MPRPGRNTYSDQ-KPPYSYISLTAMAIQSSP
: : : : :::::::.: .::: .::
NP_004 LASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRSPLVKPPYSYIALITMAILQSP
90 100 110 120 130 140
40 50 60 70 80 90
pF1KB9 EKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALH
.: : :::: .:: :::::::. ::::.:::::.::::.::::.: .::::..:.:
NP_004 KKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLD
150 160 170 180 190 200
100 110 120 130 140
pF1KB9 PSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAAS--GTHLP
: .:::.::::::::::: : . : : .: . . . :: .: ::. :. ::
NP_004 PESADMFDNGSFLRRRKRF---KRQPLPPPHPH---PHPHPELLLRGGAAAAGDPGAFLP
210 220 230 240 250
150 160 170 180 190 200
pF1KB9 QMPA-AAYNLG-GVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQPVPAAYPLPNQLTT
. : .::. : :.: : :..: : :: .: :.
NP_004 GFAAYGAYGYGYGLALP-----------------------AYGAPPPGPAPHPHPH----
260 270 280 290
210 220 230 240 250 260
pF1KB9 MGSSLGTGWPHVYGSAGMIDSATP--ISMASGDYSAY--GVPLKPLCHAAGQTLPAIPVP
::... :. .:.: .:. : .: : : . .:: . :: :.:
NP_004 ---------PHAFAFAAAA-AAAPCQLSVPPGRAAAPPPGPPTASVFAGAG-SAPA-PAP
300 310 320 330
270 280 290 300 310
pF1KB9 IK-----PTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPAS
. : ::..::. : : . . :::: .. ::
NP_004 ASGSGPGPGPAGLPAF--LGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDAGG
340 350 360 370 380 390
320
pF1KB9 ALHSVAVH
NP_004 GAGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTA
400 410 420 430 440 450
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 496 init1: 496 opt: 532 Z-score: 342.0 bits: 71.8 E(85289): 2.6e-12
Smith-Waterman score: 554; 40.6% identity (57.3% similar) in 281 aa overlap (13-290:53-311)
10 20 30 40
pF1KB9 MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKF
:::::::.: :::: .::. : :. ::::
NP_004 GETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKF
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB9 IMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSF
: .:::.::.: ..::::.::::..::::.::::. .::::..::: :. ::::.:::
NP_004 ITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSF
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB9 LRRRKRFKVLKSD-HLAPSKPADAAQYLQQQAKLRLSALAASGTHLP-QMPAAAYNLGGV
:::::::: .:: :. ::: : .: ::... .: .::: :
NP_004 LRRRKRFK--RSDLSTYPAYMHDAAA-----AAAAAAAAAAAAAIFPGAVPAARPPYPG-
150 160 170 180 190
170 180 190 200 210
pF1KB9 AQPSGFKHP-FAIENIIAREYKMPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVY
: .:. : .: . :: .. : :: .: : : : ..
NP_004 AVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVP---ERPLSPELGPAPS--GPGGSCAF
200 210 220 230 240
220 230 240 250 260 270
pF1KB9 GSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALPALPAP
.::: ..: . : : .: : .: .::. . : : : : : .:
NP_004 ASAGAPATTTGYQPA-GCTGAR--PANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGP
250 260 270 280 290 300
280 290 300 310 320
pF1KB9 IPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH
:::.
NP_004 A------SPPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAYHARHAA
310 320 330 340 350 360
325 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:23:43 2016 done: Sat Nov 5 08:23:45 2016
Total Scan time: 8.470 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]