Result of FASTA (omim) for
pF1KB9498
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9498, 611 aa
1>>>pF1KB9498 611 - 611 aa - 611 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.1212+/-0.00043; mu= -11.1496+/- 0.027
mean_var=416.3902+/-84.776, 0's: 0 Z-trim(122.8): 47 B-trim: 0 in 0/58
Lambda= 0.062853
statistics sampled from 41512 (41569) to 41512 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.487), width: 16
Scan time: 13.640
The best scores are: opt bits E(85289)
NP_001408 (OMIM: 603928) eukaryotic translation in ( 611) 4199 395.1 3.7e-109
NP_001287750 (OMIM: 603928) eukaryotic translation ( 616) 4174 392.8 1.8e-108
NP_001317583 (OMIM: 603928) eukaryotic translation ( 572) 3170 301.8 4.3e-81
NP_071496 (OMIM: 603431) eukaryotic translation in ( 248) 321 43.1 0.0013
XP_011514858 (OMIM: 603431) PREDICTED: eukaryotic ( 250) 321 43.1 0.0013
>>NP_001408 (OMIM: 603928) eukaryotic translation initia (611 aa)
initn: 4199 init1: 4199 opt: 4199 Z-score: 2080.7 bits: 395.1 E(85289): 3.7e-109
Smith-Waterman score: 4199; 100.0% identity (100.0% similar) in 611 aa overlap (1-611:1-611)
10 20 30 40 50 60
pF1KB9 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG
550 560 570 580 590 600
610
pF1KB9 EDENEGEDYAE
:::::::::::
NP_001 EDENEGEDYAE
610
>>NP_001287750 (OMIM: 603928) eukaryotic translation ini (616 aa)
initn: 3000 init1: 3000 opt: 4174 Z-score: 2068.4 bits: 392.8 E(85289): 1.8e-108
Smith-Waterman score: 4174; 99.0% identity (99.2% similar) in 616 aa overlap (1-611:1-616)
10 20 30 40 50 60
pF1KB9 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
370 380 390 400 410 420
430 440 450 460 470
pF1KB9 GSESSQTGTSTTSSR-----NARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMP
::::::::::::::: .:::::::::::::::::::::::::::::::::::::::
NP_001 GSESSQTGTSTTSSRSKSDQDARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 APPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB9 PKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAA
550 560 570 580 590 600
600 610
pF1KB9 LSVDGEDENEGEDYAE
::::::::::::::::
NP_001 LSVDGEDENEGEDYAE
610
>>NP_001317583 (OMIM: 603928) eukaryotic translation ini (572 aa)
initn: 3937 init1: 3147 opt: 3170 Z-score: 1576.8 bits: 301.8 E(85289): 4.3e-81
Smith-Waterman score: 3863; 93.6% identity (93.6% similar) in 611 aa overlap (1-611:1-572)
10 20 30 40 50 60
pF1KB9 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRD
:::::::::::::::::::::
NP_001 ---------------------------------------SLGNRRIRVDVADQAQDKDRD
130 140
190 200 210 220 230 240
pF1KB9 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB9 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYED
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB9 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB9 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRT
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB9 GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB9 ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQT
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB9 GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG
510 520 530 540 550 560
610
pF1KB9 EDENEGEDYAE
:::::::::::
NP_001 EDENEGEDYAE
570
>>NP_071496 (OMIM: 603431) eukaryotic translation initia (248 aa)
initn: 370 init1: 139 opt: 321 Z-score: 185.6 bits: 43.1 E(85289): 0.0013
Smith-Waterman score: 329; 31.4% identity (51.8% similar) in 299 aa overlap (87-385:33-248)
60 70 80 90 100 110
pF1KB9 SNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFF
...:: :::::..::::..... .: .:
NP_071 DFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIF
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB9 RGLNISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQD
. :.: .::: :. .. ...::: :.::...::: ::. . ::.: .:::.:.
NP_071 KDLSIRSVRLVRD-KDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAE----
70 80 90 100 110
180 190 200 210 220 230
pF1KB9 KDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDG
.: .:: .: : :: : . . : .:: ::
NP_071 ------------GRKQDKGGFGFRK--------GGPDDRGMGS-SRESRGGWDS---RDD
120 130 140 150
240 250 260 270 280 290
pF1KB9 YRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGD
. .:.:: : ::: ::: :: : : .:: .: ::..
NP_071 FNSGFRD------DFLGGRG-----GSRPGDR----RTGP---PMGSRFRDGPPLRGSNM
160 170 180 190
300 310 320 330 340 350
pF1KB9 RYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTR
. : ...:. :::.:.::::.. .. :. .
NP_071 DF--REPTEEERA--------------------QRPRLQLKPRTVATPLNQVANPN----
200 210 220
360 370 380 390 400 410
pF1KB9 AASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERE
..:::::.: :: : .:::::
NP_071 -SAIFGGARP-------RE--EVVQKEQE
230 240
>>XP_011514858 (OMIM: 603431) PREDICTED: eukaryotic tran (250 aa)
initn: 407 init1: 139 opt: 321 Z-score: 185.6 bits: 43.1 E(85289): 0.0013
Smith-Waterman score: 329; 31.4% identity (51.8% similar) in 299 aa overlap (87-385:35-250)
60 70 80 90 100 110
pF1KB9 SNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFF
...:: :::::..::::..... .: .:
XP_011 SMAQPCCPLVISLNGMKRSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIF
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB9 RGLNISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQD
. :.: .::: :. .. ...::: :.::...::: ::. . ::.: .:::.:.
XP_011 KDLSIRSVRLVRD-KDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAE----
70 80 90 100 110
180 190 200 210 220 230
pF1KB9 KDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDG
.: .:: .: : :: : . . : .:: ::
XP_011 ------------GRKQDKGGFGFRK--------GGPDDRGMGS-SRESRGGWDS---RDD
120 130 140 150
240 250 260 270 280 290
pF1KB9 YRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGD
. .:.:: : ::: ::: :: : : .:: .: ::..
XP_011 FNSGFRD------DFLGGRG-----GSRPGDR----RTGP---PMGSRFRDGPPLRGSNM
160 170 180 190
300 310 320 330 340 350
pF1KB9 RYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTR
. : ...:. :::.:.::::.. .. :. .
XP_011 DF--REPTEEERA--------------------QRPRLQLKPRTVATPLNQVANPN----
200 210 220 230
360 370 380 390 400 410
pF1KB9 AASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERE
..:::::.: :: : .:::::
XP_011 -SAIFGGARP-------RE--EVVQKEQE
240 250
611 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:59:52 2016 done: Thu Nov 3 23:59:54 2016
Total Scan time: 13.640 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]