Result of FASTA (omim) for
pF1KB9472
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9472, 504 aa
1>>>pF1KB9472 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4653+/-0.000372; mu= 5.8649+/- 0.023
mean_var=308.2113+/-64.997, 0's: 0 Z-trim(122.9): 191 B-trim: 900 in 1/59
Lambda= 0.073055
statistics sampled from 41345 (41677) to 41345 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.489), width: 16
Scan time: 11.380
The best scores are: opt bits E(85289)
NP_001004356 (OMIM: 194190,605830) fibroblast grow ( 504) 3503 382.9 1.2e-105
NP_001004358 (OMIM: 194190,605830) fibroblast grow ( 504) 3503 382.9 1.2e-105
XP_011511788 (OMIM: 194190,605830) PREDICTED: fibr ( 504) 3503 382.9 1.2e-105
NP_068742 (OMIM: 194190,605830) fibroblast growth ( 504) 3503 382.9 1.2e-105
NP_001278909 (OMIM: 134935) fibroblast growth fact ( 734) 638 81.1 1.2e-14
NP_002002 (OMIM: 134935) fibroblast growth factor ( 802) 630 80.3 2.3e-14
XP_005265895 (OMIM: 134935) PREDICTED: fibroblast ( 802) 630 80.3 2.3e-14
NP_998812 (OMIM: 134935) fibroblast growth factor ( 802) 630 80.3 2.3e-14
XP_011532766 (OMIM: 134935) PREDICTED: fibroblast ( 833) 630 80.3 2.4e-14
NP_000133 (OMIM: 100800,109800,114500,134934,14600 ( 806) 629 80.2 2.5e-14
XP_006713936 (OMIM: 100800,109800,114500,134934,14 ( 807) 629 80.2 2.5e-14
XP_006713935 (OMIM: 100800,109800,114500,134934,14 ( 807) 625 79.8 3.3e-14
XP_011511724 (OMIM: 100800,109800,114500,134934,14 ( 808) 625 79.8 3.3e-14
XP_011511722 (OMIM: 100800,109800,114500,134934,14 ( 809) 625 79.8 3.3e-14
XP_016871410 (OMIM: 101200,101400,101600,123150,12 ( 804) 620 79.3 4.8e-14
NP_001307587 (OMIM: 101200,101400,101600,123150,12 ( 819) 620 79.3 4.9e-14
NP_000132 (OMIM: 101200,101400,101600,123150,12350 ( 821) 618 79.1 5.6e-14
XP_016871409 (OMIM: 101200,101400,101600,123150,12 ( 805) 615 78.7 6.9e-14
XP_006717771 (OMIM: 101200,101400,101600,123150,12 ( 839) 615 78.7 7.1e-14
NP_001156685 (OMIM: 100800,109800,114500,134934,14 ( 808) 614 78.6 7.5e-14
XP_006713934 (OMIM: 100800,109800,114500,134934,14 ( 809) 614 78.6 7.5e-14
NP_001138385 (OMIM: 101200,101400,101600,123150,12 ( 769) 613 78.5 7.8e-14
XP_006717773 (OMIM: 101200,101400,101600,123150,12 ( 807) 613 78.5 8e-14
NP_075259 (OMIM: 101200,101400,101600,123150,12350 ( 822) 613 78.5 8.1e-14
NP_075252 (OMIM: 134935) fibroblast growth factor ( 762) 612 78.4 8.3e-14
XP_006713933 (OMIM: 100800,109800,114500,134934,14 ( 810) 606 77.8 1.3e-13
XP_006713932 (OMIM: 100800,109800,114500,134934,14 ( 810) 606 77.8 1.3e-13
XP_006713931 (OMIM: 100800,109800,114500,134934,14 ( 811) 606 77.8 1.3e-13
XP_016868714 (OMIM: 101600,123150,136350,147950,16 ( 818) 584 75.5 6.7e-13
XP_016868713 (OMIM: 101600,123150,136350,147950,16 ( 818) 584 75.5 6.7e-13
NP_056934 (OMIM: 101600,123150,136350,147950,16625 ( 820) 584 75.5 6.7e-13
NP_001167536 (OMIM: 101600,123150,136350,147950,16 ( 820) 584 75.5 6.7e-13
XP_016868712 (OMIM: 101600,123150,136350,147950,16 ( 828) 584 75.5 6.8e-13
XP_006716370 (OMIM: 101600,123150,136350,147950,16 ( 830) 584 75.5 6.8e-13
XP_006716369 (OMIM: 101600,123150,136350,147950,16 ( 830) 584 75.5 6.8e-13
XP_016868709 (OMIM: 101600,123150,136350,147950,16 ( 851) 584 75.5 6.9e-13
NP_001167538 (OMIM: 101600,123150,136350,147950,16 ( 853) 584 75.5 6.9e-13
XP_016868708 (OMIM: 101600,123150,136350,147950,16 ( 861) 584 75.5 6.9e-13
XP_011542746 (OMIM: 101600,123150,136350,147950,16 ( 863) 584 75.5 7e-13
NP_001167534 (OMIM: 101600,123150,136350,147950,16 ( 820) 580 75.0 9e-13
NP_075598 (OMIM: 101600,123150,136350,147950,16625 ( 822) 580 75.0 9e-13
XP_016868711 (OMIM: 101600,123150,136350,147950,16 ( 830) 580 75.1 9.1e-13
XP_016868710 (OMIM: 101600,123150,136350,147950,16 ( 832) 580 75.1 9.1e-13
XP_006716366 (OMIM: 101600,123150,136350,147950,16 ( 832) 580 75.1 9.1e-13
XP_006716367 (OMIM: 101600,123150,136350,147950,16 ( 832) 580 75.1 9.1e-13
XP_011542749 (OMIM: 101600,123150,136350,147950,16 ( 853) 580 75.1 9.2e-13
XP_011542748 (OMIM: 101600,123150,136350,147950,16 ( 855) 580 75.1 9.3e-13
XP_011542747 (OMIM: 101600,123150,136350,147950,16 ( 863) 580 75.1 9.3e-13
XP_011542745 (OMIM: 101600,123150,136350,147950,16 ( 865) 580 75.1 9.3e-13
NP_001167535 (OMIM: 101600,123150,136350,147950,16 ( 812) 573 74.3 1.5e-12
>>NP_001004356 (OMIM: 194190,605830) fibroblast growth f (504 aa)
initn: 3503 init1: 3503 opt: 3503 Z-score: 2017.6 bits: 382.9 E(85289): 1.2e-105
Smith-Waterman score: 3503; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
430 440 450 460 470 480
490 500
pF1KB9 HTHTHSHTHSHVEGKVHQHIHYQC
::::::::::::::::::::::::
NP_001 HTHTHSHTHSHVEGKVHQHIHYQC
490 500
>>NP_001004358 (OMIM: 194190,605830) fibroblast growth f (504 aa)
initn: 3503 init1: 3503 opt: 3503 Z-score: 2017.6 bits: 382.9 E(85289): 1.2e-105
Smith-Waterman score: 3503; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
430 440 450 460 470 480
490 500
pF1KB9 HTHTHSHTHSHVEGKVHQHIHYQC
::::::::::::::::::::::::
NP_001 HTHTHSHTHSHVEGKVHQHIHYQC
490 500
>>XP_011511788 (OMIM: 194190,605830) PREDICTED: fibrobla (504 aa)
initn: 3503 init1: 3503 opt: 3503 Z-score: 2017.6 bits: 382.9 E(85289): 1.2e-105
Smith-Waterman score: 3503; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
430 440 450 460 470 480
490 500
pF1KB9 HTHTHSHTHSHVEGKVHQHIHYQC
::::::::::::::::::::::::
XP_011 HTHTHSHTHSHVEGKVHQHIHYQC
490 500
>>NP_068742 (OMIM: 194190,605830) fibroblast growth fact (504 aa)
initn: 3503 init1: 3503 opt: 3503 Z-score: 2017.6 bits: 382.9 E(85289): 1.2e-105
Smith-Waterman score: 3503; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 DITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHT
430 440 450 460 470 480
490 500
pF1KB9 HTHTHSHTHSHVEGKVHQHIHYQC
::::::::::::::::::::::::
NP_068 HTHTHSHTHSHVEGKVHQHIHYQC
490 500
>>NP_001278909 (OMIM: 134935) fibroblast growth factor r (734 aa)
initn: 432 init1: 200 opt: 638 Z-score: 383.8 bits: 81.1 E(85289): 1.2e-14
Smith-Waterman score: 653; 31.9% identity (57.9% similar) in 470 aa overlap (6-437:3-451)
10 20 30 40 50
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGP------PKMADKVVPRQ---VARLGRTVRLQC
::: :: :: ::. . .. : .: .. .. .. ::. ::: :
NP_001 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCC
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSV
: : :.: : .: : : :.. . :::: :.: : ::. :
NP_001 ---GRAERGGHWYKEGSRLAPAG--RVRGWRGRLEIASFLPEDAGRYLCLAR---GSMIV
60 70 80 90 100
120 130 140 150 160
pF1KB9 --NYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSV
: ::.. :... .... : : .. . : : : .:.:..:.... : :.:..:
NP_001 LQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQA-PYWTHPQRMEKKLHAVPAGNTV
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB9 RLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSN
...: :.:.: : : :.:: ::. .: . . :...:.: .... : : : ::: : :
NP_001 KFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVEN
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 RAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE
.:.: .: .::..:. .:.: . :.:::. :. . . ::: ::..: :::::..
NP_001 AVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIV
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB9 YGAEGRHNSTIDVGGQKFV-VLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTM
..:.. . : .: :: :.:. ..: .. : . . .::: : ::..:..
NP_001 I-----NGSSFGADGFPYVQVLKTADI----NSSEVEVLYLRNVSAEDAGEYTCLAGNSI
290 300 310 320 330
350 360 370 380
pF1KB9 GYSFRSAFLTVLPDPKPP---GPPVASSSSATSLP------W-PVVIGIPAG-----AVF
: :..::.:::::. : . : ::: . .:: : . .. ::. : .
NP_001 GLSYQSAWLTVLPEEDPTWTAAAPEASSPWSQALPASQAHPWYEACVSPPAAPPCSPASL
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB9 ILGTLLLWLCQAQKKPCTPAPAPPLPGHRPPGTA-------RDRSGDKDLPSLAALSAGP
.:: : : .: . : : . :: .. .: ..:::: .:..
NP_001 VLGKPLGEGCFGQ---VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVM
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB9 GVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQHIHY
NP_001 KLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPL
460 470 480 490 500 510
>>NP_002002 (OMIM: 134935) fibroblast growth factor rece (802 aa)
initn: 474 init1: 255 opt: 630 Z-score: 378.9 bits: 80.3 E(85289): 2.3e-14
Smith-Waterman score: 631; 30.9% identity (57.6% similar) in 472 aa overlap (6-461:3-448)
10 20 30 40 50
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGP------PKMADKVVPRQ---VARLGRTVRLQC
::: :: :: ::. . .. : .: .. .. .. ::. ::: :
NP_002 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCC
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSV
: : :.: : .: : : :.. . :::: :.: : ::. :
NP_002 ---GRAERGGHWYKEGSRLAPAG--RVRGWRGRLEIASFLPEDAGRYLCLAR---GSMIV
60 70 80 90 100
120 130 140 150 160
pF1KB9 --NYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSV
: ::.. :... .... : : .. . : : : .:.:..:.... : :.:..:
NP_002 LQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQA-PYWTHPQRMEKKLHAVPAGNTV
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB9 RLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSN
...: :.:.: : : :.:: ::. .: . . :...:.: .... : : : ::: : :
NP_002 KFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVEN
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 RAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE
.:.: .: .::..:. .:.: . :.:::. :. . . ::: ::..: :::::..
NP_002 AVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIV
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB9 YGAEGRHNSTIDVGGQKFV-VLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTM
..:.. . : .: :: :.:. ..: .. : . . .::: : ::..:..
NP_002 I-----NGSSFGADGFPYVQVLKTADI----NSSEVEVLYLRNVSAEDAGEYTCLAGNSI
290 300 310 320 330
350 360 370 380 390 400
pF1KB9 GYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKK
: :..::.:::::. : .: . :.. . .. .....:. : ..
NP_002 GLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRH
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB9 PCTPAPAPPLPGHRPPGTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGP
: :: . : : : ::. : .. . .. : :: : : ..: : :
NP_002 PRPPATVQKL--SRFP-LARQFSLESGSSGKSSSSLVRGVRL-----SSSGPALLAGLVS
400 410 420 430 440 450
470 480 490 500
pF1KB9 VAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQHIHYQC
NP_002 LDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASD
460 470 480 490 500 510
>>XP_005265895 (OMIM: 134935) PREDICTED: fibroblast grow (802 aa)
initn: 474 init1: 255 opt: 630 Z-score: 378.9 bits: 80.3 E(85289): 2.3e-14
Smith-Waterman score: 631; 30.9% identity (57.6% similar) in 472 aa overlap (6-461:3-448)
10 20 30 40 50
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGP------PKMADKVVPRQ---VARLGRTVRLQC
::: :: :: ::. . .. : .: .. .. .. ::. ::: :
XP_005 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCC
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSV
: : :.: : .: : : :.. . :::: :.: : ::. :
XP_005 ---GRAERGGHWYKEGSRLAPAG--RVRGWRGRLEIASFLPEDAGRYLCLAR---GSMIV
60 70 80 90 100
120 130 140 150 160
pF1KB9 --NYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSV
: ::.. :... .... : : .. . : : : .:.:..:.... : :.:..:
XP_005 LQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQA-PYWTHPQRMEKKLHAVPAGNTV
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB9 RLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSN
...: :.:.: : : :.:: ::. .: . . :...:.: .... : : : ::: : :
XP_005 KFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVEN
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 RAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE
.:.: .: .::..:. .:.: . :.:::. :. . . ::: ::..: :::::..
XP_005 AVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIV
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB9 YGAEGRHNSTIDVGGQKFV-VLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTM
..:.. . : .: :: :.:. ..: .. : . . .::: : ::..:..
XP_005 I-----NGSSFGADGFPYVQVLKTADI----NSSEVEVLYLRNVSAEDAGEYTCLAGNSI
290 300 310 320 330
350 360 370 380 390 400
pF1KB9 GYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKK
: :..::.:::::. : .: . :.. . .. .....:. : ..
XP_005 GLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRH
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB9 PCTPAPAPPLPGHRPPGTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGP
: :: . : : : ::. : .. . .. : :: : : ..: : :
XP_005 PRPPATVQKL--SRFP-LARQFSLESGSSGKSSSSLVRGVRL-----SSSGPALLAGLVS
400 410 420 430 440 450
470 480 490 500
pF1KB9 VAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQHIHYQC
XP_005 LDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASD
460 470 480 490 500 510
>>NP_998812 (OMIM: 134935) fibroblast growth factor rece (802 aa)
initn: 474 init1: 255 opt: 630 Z-score: 378.9 bits: 80.3 E(85289): 2.3e-14
Smith-Waterman score: 631; 30.9% identity (57.6% similar) in 472 aa overlap (6-461:3-448)
10 20 30 40 50
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGP------PKMADKVVPRQ---VARLGRTVRLQC
::: :: :: ::. . .. : .: .. .. .. ::. ::: :
NP_998 MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCC
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSV
: : :.: : .: : : :.. . :::: :.: : ::. :
NP_998 ---GRAERGGHWYKEGSRLAPAG--RVRGWRGRLEIASFLPEDAGRYLCLAR---GSMIV
60 70 80 90 100
120 130 140 150 160
pF1KB9 --NYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSV
: ::.. :... .... : : .. . : : : .:.:..:.... : :.:..:
NP_998 LQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQA-PYWTHPQRMEKKLHAVPAGNTV
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB9 RLKCVASGHPRPDITWMKDDQAL---TRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSN
...: :.:.: : : :.:: ::. .: . . :...:.: .... : : : ::: : :
NP_998 KFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVEN
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB9 RAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE
.:.: .: .::..:. .:.: . :.:::. :. . . ::: ::..: :::::..
NP_998 AVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIV
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB9 YGAEGRHNSTIDVGGQKFV-VLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTM
..:.. . : .: :: :.:. ..: .. : . . .::: : ::..:..
NP_998 I-----NGSSFGADGFPYVQVLKTADI----NSSEVEVLYLRNVSAEDAGEYTCLAGNSI
290 300 310 320 330
350 360 370 380 390 400
pF1KB9 GYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKK
: :..::.:::::. : .: . :.. . .. .....:. : ..
NP_998 GLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRH
340 350 360 370 380 390
410 420 430 440 450 460
pF1KB9 PCTPAPAPPLPGHRPPGTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGP
: :: . : : : ::. : .. . .. : :: : : ..: : :
NP_998 PRPPATVQKL--SRFP-LARQFSLESGSSGKSSSSLVRGVRL-----SSSGPALLAGLVS
400 410 420 430 440 450
470 480 490 500
pF1KB9 VAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQHIHYQC
NP_998 LDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASD
460 470 480 490 500 510
>>XP_011532766 (OMIM: 134935) PREDICTED: fibroblast grow (833 aa)
initn: 474 init1: 255 opt: 630 Z-score: 378.7 bits: 80.3 E(85289): 2.4e-14
Smith-Waterman score: 631; 30.9% identity (57.6% similar) in 472 aa overlap (6-461:34-479)
10 20
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGP------P
::: :: :: ::. . .. :
XP_011 KWSGSDQGGGGRQLVGSPAWVPESCEKEMRLLLALLGVLLSVPGPPVLSLEASEEVELEP
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB9 KMADKVVPRQ---VARLGRTVRLQCPVEGDPPPLTMWTKDG-RTIHSGWSRFRVLPQGLK
.: .. .. .. ::. ::: : : : :.: : .: : : :.
XP_011 CLAPSLEQQEQELTVALGQPVRLCC---GRAERGGHWYKEGSRLAPAG--RVRGWRGRLE
70 80 90 100 110
90 100 110 120 130 140
pF1KB9 VKQVEREDAGVYVCKATNGFGSLSV--NYTLVVLDDISPGKESLGPDSSSGGQEDPASQQ
. . :::: :.: : ::. : : ::.. :... .... : : .. . :
XP_011 IASFLPEDAGRYLCLAR---GSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQ
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB9 WARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQAL---TRPEAAEPR
: : .:.:..:.... : :.:..:...: :.:.: : : :.:: ::. .: . . :
XP_011 QA-PYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLR
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB9 KKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDF
...:.: .... : : : ::: : : .:.: .: .::..:. .:.: . :.:::.
XP_011 HQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVV
240 250 260 270 280 290
270 280 290 300 310
pF1KB9 GGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGGQKFV-VLPTGDVWSRPDGSY
:. . . ::: ::..: :::::.. ..:.. . : .: :: :.:. ..:
XP_011 GSDVELLCKVYSDAQPHIQWLKHIVI-----NGSSFGADGFPYVQVLKTADI----NSSE
300 310 320 330 340
320 330 340 350 360 370
pF1KB9 LNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWPV
.. : . . .::: : ::..:..: :..::.:::::. : .: . :.. .
XP_011 VEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYA
350 360 370 380 390 400
380 390 400 410 420 430
pF1KB9 VIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPPGTARDRSGDKDLPSLAALS
.. .....:. : ..: :: . : : : ::. : .. . .. :
XP_011 SGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKL--SRFP-LARQFSLESGSSGKSSSS
410 420 430 440 450 460
440 450 460 470 480 490
pF1KB9 AGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQH
:: : : ..: : :
XP_011 LVRGVRL-----SSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEA
470 480 490 500 510
>>NP_000133 (OMIM: 100800,109800,114500,134934,146000,14 (806 aa)
initn: 493 init1: 281 opt: 629 Z-score: 378.3 bits: 80.2 E(85289): 2.5e-14
Smith-Waterman score: 651; 30.8% identity (58.6% similar) in 454 aa overlap (22-457:35-464)
10 20 30 40 50
pF1KB9 MTPSPLLLLLLPPLLLGAFPPAAAARGP-PKMADKVVPRQVARLGRTVRLQ
:: . :: : . ...: . : .:.:.
NP_000 ACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGS----GDAVELS
10 20 30 40 50 60
60 70 80 90 100
pF1KB9 CPVEGDPP--PLTMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSL
:: : : : :.:.::: . . : : :: :.: .. .::.:.: :. :
NP_000 CPPPGGGPMGP-TVWVKDGTGLVPS-ERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVL
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 SVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSV
.... : : : : . : : . : .. :.::. .: ....: :....:
NP_000 C-HFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPE-----RMDKKLLAVPAANTV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 RLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSN
:..: :.:.: :.:.:.:. . . : . . :...:.: .... : : :.::: : :
NP_000 RFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVEN
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB9 RAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVE
. :.: :: .::..:. .:.: . :.: :. .:. . :.::: ::..: :::::.::
NP_000 KFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB9 YGAEGRHNSTIDVGGQKFV-VLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTM
..: . : .: :: :. . . :. : . . .::: : ::..:..
NP_000 V-----NGSKVGPDGTPYVTVLKTAG--ANTTDKELEVLSLHNVTFEDAGEYTCLAGNSI
300 310 320 330 340
350 360 370 380 390 400
pF1KB9 GYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWPVVIGIPAGA-VFILGTLLLWLCQAQK
:.: .::.:.::: . .. .. : :. . ... .: .::: . . ::. ..
NP_000 GFSHHSAWLVVLPAEEE----LVEADEAGSV-YAGILSYGVGFFLFILVVAAVTLCRLRS
350 360 370 380 390 400
410 420 430 440 450
pF1KB9 KPCTPAPAPPL------PGHRPPGTARDRSGDKDLP--SLAALSAGPGVGLCE--EHGSP
: .: . : .: . . : ... : .: ::.: : : . : :
NP_000 PPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELP
410 420 430 440 450 460
460 470 480 490 500
pF1KB9 AAPQHLLGPGPVAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQHIHYQC
: :.
NP_000 ADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLS
470 480 490 500 510 520
504 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:42:35 2016 done: Thu Nov 3 23:42:37 2016
Total Scan time: 11.380 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]