Result of FASTA (omim) for
pF1KB9470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9470, 655 aa
1>>>pF1KB9470 655 - 655 aa - 655 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3573+/-0.00038; mu= 1.8291+/- 0.024
mean_var=265.1150+/-54.443, 0's: 0 Z-trim(121.2): 403 B-trim: 0 in 0/54
Lambda= 0.078769
statistics sampled from 37136 (37589) to 37136 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.441), width: 16
Scan time: 14.130
The best scores are: opt bits E(85289)
XP_016871959 (OMIM: 610585) PREDICTED: rho GTPase- ( 655) 4383 511.7 3.3e-144
XP_011538308 (OMIM: 610585) PREDICTED: rho GTPase- ( 661) 4307 503.1 1.3e-141
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 3637 426.9 1.1e-118
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 3637 426.9 1.1e-118
XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase- ( 637) 3637 426.9 1.1e-118
XP_011538314 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 3635 426.6 1.1e-118
XP_016871961 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 3635 426.6 1.1e-118
XP_016871960 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 3635 426.6 1.1e-118
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 3637 427.0 1.2e-118
XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 3637 427.0 1.2e-118
XP_011538304 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 3637 427.0 1.2e-118
XP_011538313 (OMIM: 610585) PREDICTED: rho GTPase- ( 565) 3625 425.5 2.6e-118
NP_001242955 (OMIM: 610585) rho GTPase-activating ( 608) 3625 425.5 2.7e-118
NP_067049 (OMIM: 610585) rho GTPase-activating pro ( 698) 3625 425.6 3e-118
XP_011538306 (OMIM: 610585) PREDICTED: rho GTPase- ( 704) 3625 425.6 3e-118
NP_001242954 (OMIM: 610585) rho GTPase-activating ( 704) 3625 425.6 3e-118
XP_016871966 (OMIM: 610585) PREDICTED: rho GTPase- ( 396) 2610 310.0 1e-83
XP_016871964 (OMIM: 610585) PREDICTED: rho GTPase- ( 415) 2441 290.8 6.5e-78
XP_016871963 (OMIM: 610585) PREDICTED: rho GTPase- ( 415) 2441 290.8 6.5e-78
XP_005264733 (OMIM: 610587) PREDICTED: rho GTPase- ( 607) 1295 160.8 1.4e-38
NP_001159749 (OMIM: 610587) rho GTPase-activating ( 606) 1283 159.4 3.5e-38
XP_016860914 (OMIM: 610587) PREDICTED: rho GTPase- ( 611) 1282 159.3 3.8e-38
XP_011538315 (OMIM: 610585) PREDICTED: rho GTPase- ( 436) 1211 151.1 8e-36
XP_011538317 (OMIM: 610585) PREDICTED: rho GTPase- ( 359) 1202 150.0 1.4e-35
XP_016871965 (OMIM: 610585) PREDICTED: rho GTPase- ( 414) 1199 149.7 2e-35
XP_016871962 (OMIM: 610585) PREDICTED: rho GTPase- ( 420) 1199 149.7 2e-35
NP_112595 (OMIM: 610586) rho GTPase-activating pro ( 655) 1111 139.9 2.9e-32
NP_001036134 (OMIM: 610586) rho GTPase-activating ( 653) 1102 138.9 5.8e-32
XP_011530602 (OMIM: 610586) PREDICTED: rho GTPase- ( 653) 1102 138.9 5.8e-32
NP_001274734 (OMIM: 610586) rho GTPase-activating ( 663) 1102 138.9 5.9e-32
NP_001020787 (OMIM: 610586) rho GTPase-activating ( 748) 1102 138.9 6.4e-32
NP_055697 (OMIM: 610587) rho GTPase-activating pro ( 638) 952 121.8 7.7e-27
XP_005264732 (OMIM: 610587) PREDICTED: rho GTPase- ( 645) 952 121.8 7.8e-27
XP_016860913 (OMIM: 610587) PREDICTED: rho GTPase- ( 649) 952 121.8 7.8e-27
XP_011531511 (OMIM: 610587) PREDICTED: rho GTPase- ( 528) 941 120.5 1.6e-26
XP_011531509 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 942 120.7 1.7e-26
XP_011531508 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 942 120.7 1.7e-26
XP_011531510 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 942 120.7 1.7e-26
NP_001159748 (OMIM: 610587) rho GTPase-activating ( 639) 942 120.7 1.7e-26
NP_001007232 (OMIM: 610587) rho GTPase-activating ( 646) 942 120.7 1.7e-26
XP_016860912 (OMIM: 610587) PREDICTED: rho GTPase- ( 650) 942 120.7 1.7e-26
NP_001333022 (OMIM: 610586) rho GTPase-activating ( 555) 704 93.6 2.1e-18
XP_016860917 (OMIM: 610587) PREDICTED: rho GTPase- ( 313) 521 72.5 2.5e-12
XP_011532603 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 941) 449 64.8 1.7e-09
XP_011532598 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1085) 449 64.8 1.8e-09
XP_011532597 (OMIM: 606525) PREDICTED: SLIT-ROBO R (1104) 449 64.8 1.9e-09
XP_016863067 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 442 64.0 3e-09
XP_016863066 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 442 64.0 3e-09
XP_016863065 (OMIM: 606525) PREDICTED: SLIT-ROBO R ( 979) 442 64.0 3e-09
NP_055665 (OMIM: 606525) SLIT-ROBO Rho GTPase-acti (1099) 442 64.0 3.2e-09
>>XP_016871959 (OMIM: 610585) PREDICTED: rho GTPase-acti (655 aa)
initn: 4383 init1: 4383 opt: 4383 Z-score: 2709.9 bits: 511.7 E(85289): 3.3e-144
Smith-Waterman score: 4383; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KB9 MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 VHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 KHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 GSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 EPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELD
550 560 570 580 590 600
610 620 630 640 650
pF1KB9 QEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
610 620 630 640 650
>>XP_011538308 (OMIM: 610585) PREDICTED: rho GTPase-acti (661 aa)
initn: 4307 init1: 4307 opt: 4307 Z-score: 2663.1 bits: 503.1 E(85289): 1.3e-141
Smith-Waterman score: 4307; 100.0% identity (100.0% similar) in 643 aa overlap (13-655:19-661)
10 20 30 40 50
pF1KB9 MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNW
::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPTASSKRRTFAARYFTRSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 QQRWFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQRWFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 EETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EETVHHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 FDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDSTTDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 QANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 MTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 GAAVAVLSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAVAVLSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 GNWLMNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNWLMNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 SESSVGGSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESSVGGSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB9 SNSEPSEPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNSEPSEPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB9 LEEELDQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEELDQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAP
610 620 630 640 650 660
pF1KB9 K
:
XP_011 K
>>XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase-acti (624 aa)
initn: 3637 init1: 3637 opt: 3637 Z-score: 2252.0 bits: 426.9 E(85289): 1.1e-118
Smith-Waterman score: 3637; 99.3% identity (99.5% similar) in 554 aa overlap (102-655:71-624)
80 90 100 110 120 130
pF1KB9 KDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHHERKYGPRLAPL
: . :::::::::::::::::::::::::
XP_005 RDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHHERKYGPRLAPL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB9 LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB9 LRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEV
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB9 QAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVP
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB9 EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB9 RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRA
350 360 370 380 390 400
440 450 460 470 480 490
pF1KB9 SSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRA
410 420 430 440 450 460
500 510 520 530 540 550
pF1KB9 SDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHAR
470 480 490 500 510 520
560 570 580 590 600 610
pF1KB9 RSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEI
530 540 550 560 570 580
620 630 640 650
pF1KB9 KLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
590 600 610 620
>>XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase-acti (624 aa)
initn: 3637 init1: 3637 opt: 3637 Z-score: 2252.0 bits: 426.9 E(85289): 1.1e-118
Smith-Waterman score: 3637; 99.3% identity (99.5% similar) in 554 aa overlap (102-655:71-624)
80 90 100 110 120 130
pF1KB9 KDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHHERKYGPRLAPL
: . :::::::::::::::::::::::::
XP_011 RDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHHERKYGPRLAPL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB9 LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB9 LRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEV
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB9 QAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVP
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB9 EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB9 RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRA
350 360 370 380 390 400
440 450 460 470 480 490
pF1KB9 SSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRA
410 420 430 440 450 460
500 510 520 530 540 550
pF1KB9 SDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHAR
470 480 490 500 510 520
560 570 580 590 600 610
pF1KB9 RSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEI
530 540 550 560 570 580
620 630 640 650
pF1KB9 KLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
590 600 610 620
>>XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase-acti (637 aa)
initn: 3637 init1: 3637 opt: 3637 Z-score: 2251.9 bits: 426.9 E(85289): 1.1e-118
Smith-Waterman score: 3637; 99.3% identity (99.5% similar) in 554 aa overlap (102-655:84-637)
80 90 100 110 120 130
pF1KB9 KDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHHERKYGPRLAPL
: . :::::::::::::::::::::::::
XP_011 RDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHHERKYGPRLAPL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB9 LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLY
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB9 LRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEV
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB9 QAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVP
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB9 EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGS
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB9 RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRA
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB9 SSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRA
420 430 440 450 460 470
500 510 520 530 540 550
pF1KB9 SDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHAR
480 490 500 510 520 530
560 570 580 590 600 610
pF1KB9 RSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEI
540 550 560 570 580 590
620 630 640 650
pF1KB9 KLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
600 610 620 630
>>XP_011538314 (OMIM: 610585) PREDICTED: rho GTPase-acti (552 aa)
initn: 3635 init1: 3635 opt: 3635 Z-score: 2251.5 bits: 426.6 E(85289): 1.1e-118
Smith-Waterman score: 3635; 100.0% identity (100.0% similar) in 549 aa overlap (107-655:4-552)
80 90 100 110 120 130
pF1KB9 PQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHHERKYGPRLAPLLVEQC
::::::::::::::::::::::::::::::
XP_011 MLLPGIFGQRLEETVHHERKYGPRLAPLLVEQC
10 20 30
140 150 160 170 180 190
pF1KB9 VDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB9 EPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB9 VNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTS
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB9 PRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB9 KKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDR
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB9 LKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB9 RSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEAL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB9 QGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNS
460 470 480 490 500 510
620 630 640 650
pF1KB9 ERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
:::::::::::::::::::::::::::::::::::::::
XP_011 ERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
520 530 540 550
>>XP_016871961 (OMIM: 610585) PREDICTED: rho GTPase-acti (552 aa)
initn: 3635 init1: 3635 opt: 3635 Z-score: 2251.5 bits: 426.6 E(85289): 1.1e-118
Smith-Waterman score: 3635; 100.0% identity (100.0% similar) in 549 aa overlap (107-655:4-552)
80 90 100 110 120 130
pF1KB9 PQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHHERKYGPRLAPLLVEQC
::::::::::::::::::::::::::::::
XP_016 MLLPGIFGQRLEETVHHERKYGPRLAPLLVEQC
10 20 30
140 150 160 170 180 190
pF1KB9 VDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB9 EPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB9 VNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTS
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB9 PRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB9 KKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDR
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB9 LKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB9 RSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEAL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB9 QGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNS
460 470 480 490 500 510
620 630 640 650
pF1KB9 ERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
:::::::::::::::::::::::::::::::::::::::
XP_016 ERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
520 530 540 550
>>XP_016871960 (OMIM: 610585) PREDICTED: rho GTPase-acti (552 aa)
initn: 3635 init1: 3635 opt: 3635 Z-score: 2251.5 bits: 426.6 E(85289): 1.1e-118
Smith-Waterman score: 3635; 100.0% identity (100.0% similar) in 549 aa overlap (107-655:4-552)
80 90 100 110 120 130
pF1KB9 PQGFISLQGTQVTELPPGPEDPGKHLFEISPGIFGQRLEETVHHERKYGPRLAPLLVEQC
::::::::::::::::::::::::::::::
XP_016 MLLPGIFGQRLEETVHHERKYGPRLAPLLVEQC
10 20 30
140 150 160 170 180 190
pF1KB9 VDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB9 EPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB9 VNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTS
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB9 PRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVLSRTAPTGPGSRCSPG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB9 KKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRGHRRASSGDR
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB9 LKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB9 RSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEAL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB9 QGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYIMLEIKLRNS
460 470 480 490 500 510
620 630 640 650
pF1KB9 ERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
:::::::::::::::::::::::::::::::::::::::
XP_016 ERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
520 530 540 550
>>NP_001242953 (OMIM: 610585) rho GTPase-activating prot (714 aa)
initn: 3637 init1: 3637 opt: 3637 Z-score: 2251.2 bits: 427.0 E(85289): 1.2e-118
Smith-Waterman score: 4083; 91.4% identity (91.4% similar) in 687 aa overlap (28-655:28-714)
10 20 30 40 50 60
pF1KB9 MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFV
:::::::::::::::::::::::::::::::::
NP_001 MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFV
10 20 30 40 50 60
70 80 90 100
pF1KB9 LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPG------------
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANP
70 80 90 100 110 120
110 120
pF1KB9 -----------------------------------------------IFGQRLEETVHHE
:::::::::::::
NP_001 EALLLMASSQRDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHHE
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB9 RKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDV
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB9 HTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB9 RYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRK
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB9 HSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAVAVL
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB9 SRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNG
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB9 LSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGG
490 500 510 520 530 540
490 500 510 520 530 540
pF1KB9 SLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSE
550 560 570 580 590 600
550 560 570 580 590 600
pF1KB9 PDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQ
610 620 630 640 650 660
610 620 630 640 650
pF1KB9 EKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
670 680 690 700 710
>>XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase-acti (720 aa)
initn: 3637 init1: 3637 opt: 3637 Z-score: 2251.2 bits: 427.0 E(85289): 1.2e-118
Smith-Waterman score: 4083; 91.4% identity (91.4% similar) in 687 aa overlap (28-655:34-720)
10 20 30 40 50
pF1KB9 MLSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQR
::::::::::::::::::::::::::::::
XP_011 TASSKRRTFAARYFTRSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQR
10 20 30 40 50 60
60 70 80 90 100
pF1KB9 WFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPG---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WFVLRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVP
70 80 90 100 110 120
110
pF1KB9 --------------------------------------------------IFGQRLEETV
::::::::::
XP_011 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETV
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB9 HHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHERKYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDST
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB9 TDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANY
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB9 NLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVL
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB9 IRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDGAAV
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB9 AVLSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVLSRTAPTGPGSRCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWL
430 440 450 460 470 480
420 430 440 450 460 470
pF1KB9 MNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGLSSLRGHRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESS
490 500 510 520 530 540
480 490 500 510 520 530
pF1KB9 VGGSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGGSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSE
550 560 570 580 590 600
540 550 560 570 580 590
pF1KB9 PSEPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSEPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEE
610 620 630 640 650 660
600 610 620 630 640 650
pF1KB9 LDQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDQEKKKYIMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGSLTVGAKGARAPK
670 680 690 700 710 720
655 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:41:13 2016 done: Thu Nov 3 23:41:15 2016
Total Scan time: 14.130 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]