Result of FASTA (omim) for
pF1KB9465
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9465, 1037 aa
1>>>pF1KB9465 1037 - 1037 aa - 1037 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.8242+/-0.000759; mu= -14.7873+/- 0.046
mean_var=565.3662+/-117.690, 0's: 0 Z-trim(113.9): 63 B-trim: 332 in 1/53
Lambda= 0.053940
statistics sampled from 23503 (23537) to 23503 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.276), width: 16
Scan time: 15.840
The best scores are: opt bits E(85289)
XP_011514418 (OMIM: 176807,601767) PREDICTED: hunt (1037) 6664 535.5 5.6e-151
NP_005329 (OMIM: 176807,601767) huntingtin-interac (1037) 6664 535.5 5.6e-151
XP_016867588 (OMIM: 176807,601767) PREDICTED: hunt (1023) 6413 516.0 4.2e-145
XP_005250361 (OMIM: 176807,601767) PREDICTED: hunt (1008) 6408 515.6 5.5e-145
XP_005250362 (OMIM: 176807,601767) PREDICTED: hunt (1003) 6406 515.4 6.1e-145
NP_001230127 (OMIM: 176807,601767) huntingtin-inte ( 986) 5191 420.9 1.7e-116
NP_001290026 (OMIM: 605613) huntingtin-interacting ( 615) 1563 138.3 1.2e-31
XP_011537265 (OMIM: 605613) PREDICTED: huntingtin- (1056) 1546 137.3 4.5e-31
NP_003950 (OMIM: 605613) huntingtin-interacting pr (1068) 1546 137.3 4.5e-31
NP_001290028 (OMIM: 605613) huntingtin-interacting ( 603) 1479 131.8 1.1e-29
NP_006280 (OMIM: 186745) talin-1 [Homo sapiens] (2541) 382 47.1 0.0015
XP_016878157 (OMIM: 607349) PREDICTED: talin-2 iso (2542) 380 46.9 0.0017
NP_055874 (OMIM: 607349) talin-2 [Homo sapiens] (2542) 380 46.9 0.0017
>>XP_011514418 (OMIM: 176807,601767) PREDICTED: huntingt (1037 aa)
initn: 6664 init1: 6664 opt: 6664 Z-score: 2831.5 bits: 535.5 E(85289): 5.6e-151
Smith-Waterman score: 6664; 100.0% identity (100.0% similar) in 1037 aa overlap (1-1037:1-1037)
10 20 30 40 50 60
pF1KB9 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 TQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 VTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 LTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 DLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 SKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 EELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 EETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEE
970 980 990 1000 1010 1020
1030
pF1KB9 GTEASPPTLQEVVTEKE
:::::::::::::::::
XP_011 GTEASPPTLQEVVTEKE
1030
>>NP_005329 (OMIM: 176807,601767) huntingtin-interacting (1037 aa)
initn: 6664 init1: 6664 opt: 6664 Z-score: 2831.5 bits: 535.5 E(85289): 5.6e-151
Smith-Waterman score: 6664; 100.0% identity (100.0% similar) in 1037 aa overlap (1-1037:1-1037)
10 20 30 40 50 60
pF1KB9 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 TQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 VTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 LTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 DLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 SKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 EELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 EETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEE
970 980 990 1000 1010 1020
1030
pF1KB9 GTEASPPTLQEVVTEKE
:::::::::::::::::
NP_005 GTEASPPTLQEVVTEKE
1030
>>XP_016867588 (OMIM: 176807,601767) PREDICTED: huntingt (1023 aa)
initn: 6413 init1: 6413 opt: 6413 Z-score: 2726.0 bits: 516.0 E(85289): 4.2e-145
Smith-Waterman score: 6413; 99.9% identity (100.0% similar) in 999 aa overlap (39-1037:25-1023)
10 20 30 40 50 60
pF1KB9 KQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTH
:.::::::::::::::::::::::::::::
XP_016 MARPRLYQKPQKTKPLPVAPVLCGTKTVSINKAINTQEVAVKEKHARTCILGTH
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 HEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 GHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 CLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB9 SPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB9 NKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAAD
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB9 DCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRK
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB9 NAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB9 LQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLAST
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB9 EESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCI
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB9 EQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQY
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB9 GRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMA
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB9 ATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREI
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB9 VESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSH
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB9 EIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDF
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB9 SSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPT
960 970 980 990 1000 1010
1030
pF1KB9 LQEVVTEKE
:::::::::
XP_016 LQEVVTEKE
1020
>>XP_005250361 (OMIM: 176807,601767) PREDICTED: huntingt (1008 aa)
initn: 6408 init1: 6408 opt: 6408 Z-score: 2724.0 bits: 515.6 E(85289): 5.5e-145
Smith-Waterman score: 6408; 99.9% identity (100.0% similar) in 998 aa overlap (40-1037:11-1008)
10 20 30 40 50 60
pF1KB9 QVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHH
.:::::::::::::::::::::::::::::
XP_005 MMFPNPEPPPETVSINKAINTQEVAVKEKHARTCILGTHH
10 20 30 40
70 80 90 100 110 120
pF1KB9 EKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 HLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMF
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 DYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 LPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHIS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 PVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVN
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 KDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADD
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB9 CEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKN
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB9 AEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQREL
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB9 QVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTE
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB9 ESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIE
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB9 QLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQYG
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB9 RETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAA
710 720 730 740 750 760
790 800 810 820 830 840
pF1KB9 TSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIV
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB9 ESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHE
830 840 850 860 870 880
910 920 930 940 950 960
pF1KB9 IAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFS
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KB9 SMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTL
950 960 970 980 990 1000
1030
pF1KB9 QEVVTEKE
::::::::
XP_005 QEVVTEKE
>>XP_005250362 (OMIM: 176807,601767) PREDICTED: huntingt (1003 aa)
initn: 6406 init1: 6406 opt: 6406 Z-score: 2723.1 bits: 515.4 E(85289): 6.1e-145
Smith-Waterman score: 6406; 100.0% identity (100.0% similar) in 997 aa overlap (41-1037:7-1003)
20 30 40 50 60 70
pF1KB9 VPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHHE
::::::::::::::::::::::::::::::
XP_005 MDVSKMTVSINKAINTQEVAVKEKHARTCILGTHHE
10 20 30
80 90 100 110 120 130
pF1KB9 KGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGH
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB9 LSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFD
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB9 YLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB9 PADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB9 VVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNK
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB9 DEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDC
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB9 EFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNA
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB9 EVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQ
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB9 VLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEE
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB9 SMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQ
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB9 LEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQYGR
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB9 ETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAAT
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB9 SAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVE
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB9 SGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHEI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB9 AASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFSS
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KB9 MTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEGTEASPPTLQ
940 950 960 970 980 990
pF1KB9 EVVTEKE
:::::::
XP_005 EVVTEKE
1000
>>NP_001230127 (OMIM: 176807,601767) huntingtin-interact (986 aa)
initn: 6333 init1: 5189 opt: 5191 Z-score: 2212.2 bits: 420.9 E(85289): 1.7e-116
Smith-Waterman score: 6235; 95.1% identity (95.1% similar) in 1037 aa overlap (1-1037:1-986)
10 20 30 40 50 60
pF1KB9 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 TQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 VTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 LTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 DLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVA
::::::::::::::::::::::
NP_001 DLVDKEMAATSAAIETATARIE--------------------------------------
790 800
850 860 870 880 890 900
pF1KB9 SKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKF
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------GTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKF
810 820 830 840
910 920 930 940 950 960
pF1KB9 EELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQI
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KB9 EETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEE
910 920 930 940 950 960
1030
pF1KB9 GTEASPPTLQEVVTEKE
:::::::::::::::::
NP_001 GTEASPPTLQEVVTEKE
970 980
>>NP_001290026 (OMIM: 605613) huntingtin-interacting pro (615 aa)
initn: 1889 init1: 1349 opt: 1563 Z-score: 689.0 bits: 138.3 E(85289): 1.2e-31
Smith-Waterman score: 1928; 50.7% identity (77.5% similar) in 609 aa overlap (6-614:2-593)
10 20 30 40 50 60
pF1KB9 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
.:.:.:: .::::: : .::: :::.:..::..::.:::::::. ::::::
NP_001 MNSIKNVPA---RVLSRRP-GHSLEA-EREQFDKTQAISISKAINTQEAPVKEKHA
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
: :::::::::: :::: . ::: :...: ::::::.::.:::::::::.: :::..
NP_001 RRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
. ... .:::: . :::: ..: ::: ::. .: :.:.::..:...:. :..:. .::::
NP_001 IREIGDLWGHLHDRYGQLVNVYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
.::::::::::..:::.: ..:: .:. . .:: ..:::::::::::: :::::: :::
NP_001 IFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
:::::::::::::::::::::: ::: .:...: :.:.. :::::::::.:::.::::::
NP_001 KLLFKLHSCLPADTLQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB9 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
::::.:::.:::::: :: :..: : ..:...... :.: ..:. :
NP_001 ASALAEHIKPVVVIPEEA--PEDE---EPENLIEISTGPPAGEPVVVADLFDQTFGP-P-
300 310 320 330 340
370 380 390 400 410 420
pF1KB9 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
:: ::..: :: : ::. :...::..: :.:: . :::..:. ::..: ::.
NP_001 -----NGSVKDDRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQR
350 360 370 380 390
430 440 450 460 470 480
pF1KB9 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
. .:.: : : :: :: .:: . . :..: : ::::.:.: ::.:::::.::::.
NP_001 KQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVH
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB9 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
::.::::::...::.....:.: .. : :..: ..:... ... : .:. . ::.::.
NP_001 VHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKR
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB9 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQD
:: .. :: : .: . ::... .... : :.:.: ... .:: .: : .. ...
NP_001 ELEAKAGELARAQEALSHTEQSKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRE
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB9 TQLKLASTEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLST
:. :. .. :
NP_001 TEAALSREQQRSSQEQGELQGRLAERVWPPQMQQHH
580 590 600 610
>>XP_011537265 (OMIM: 605613) PREDICTED: huntingtin-inte (1056 aa)
initn: 3230 init1: 1398 opt: 1546 Z-score: 678.9 bits: 137.3 E(85289): 4.5e-31
Smith-Waterman score: 3185; 50.6% identity (77.4% similar) in 1017 aa overlap (42-1037:21-1025)
20 30 40 50 60 70
pF1KB9 PNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHHEK
.::.:::::::. ::::::: ::::::::
XP_011 MEARFSPINQILPWCRQDLAISISKAINTQEAPVKEKHARRIILGTHHEK
10 20 30 40 50
80 90 100 110 120 130
pF1KB9 GAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHL
:: :::: . ::: :...: ::::::.::.:::::::::.: :::... ... .::::
XP_011 GAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB9 SEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDY
. :::: ..: ::: ::. .: :.:.::..:...:. :..:. .::::.::::::::::
XP_011 HDRYGQLVNVYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDY
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB9 LECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLP
..:::.: ..:: .:. . .:: ..:::::::::::: :::::: ::::::::::::::
XP_011 MDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLLFKLHSCLP
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB9 ADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPV
::::::::::: ::: .:...: :.:.. :::::::::.:::.::::::::::.:::.::
XP_011 ADTLQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPV
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB9 VVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNKD
:::: :: :..: : ..:...... :.: ..:. : :: ::
XP_011 VVIPEEA--PEDE---EPENLIEISTGPPAGEPVVVADLFDQTFGP-P------NGSVKD
300 310 320 330
380 390 400 410 420 430
pF1KB9 EKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCE
..: :: : ::. :...::..: :.:: . :::..:. ::..: ::.. .:.: : :
XP_011 DRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNE
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB9 FLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAE
:: :: .:: . . :..: : ::::.:.: ::.:::::.::::. ::.::::::.
XP_011 QLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNAD
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB9 VTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQV
..::.....:.: .. : :..: ..:... ... : .:. . ::.::.:: .. ::
XP_011 TAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELAR
460 470 480 490 500 510
560 570 580 590
pF1KB9 LQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEEL-----------SALRKELQ-
: .: . ::... .... : :.:.: ... .:: .: .:: .: :
XP_011 AQEALSHTEQSKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQR
520 530 540 550 560 570
600 610 620 630 640 650
pF1KB9 ------DTQLKLA---STEESMCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISC
. : .:: : :... : :.. .: :. : ..:::...:..: . :
XP_011 SSQEQGELQGRLAERESQEQGLRQRLLDEQFAVLRGAAAEAAGILQDAVSKLDDPLHLRC
580 590 600 610 620 630
660 670 680 690 700 710
pF1KB9 AGSADHLLSTVTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTC
..: :.:.: . . . ::.. .:::. : :.:. ..: ..::..:.: .:..:
XP_011 TSSPDYLVSRAQEALDAVSTLEEGHAQYLTSLADASALVAALTRFSHLAADTIINGGATS
640 650 660 670 680 690
720 730 740 750 760 770
pF1KB9 LRAPPEPADSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPR
:: .::: : ..:.. : ..: ...:... .:.. ... .:. :. : .:.:: :.
XP_011 HLAPTDPADRLIDTCRECGARALELMGQLQDQQALRHMQASLVRTPLQGILQLGQELKPK
700 710 720 730 740 750
780 790 800 810 820 830
pF1KB9 GLDIKQEELGDLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSL
.::..::::: .::::::::::::: :. :::.:....: ...:::::::::::. ::.:
XP_011 SLDVRQEELGAVVDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEVNERILNSCTDL
760 770 780 790 800 810
840 850 860 870 880 890
pF1KB9 MQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAA
:.::..:...: .::.::::::::.:. .::::::::::::::::::::::::: .:.::
XP_011 MKAIRLLVTTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVEAA
820 830 840 850 860 870
900 910 920 930 940 950
pF1KB9 DLVVQGRGKFEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVV
: :: ::.:::.:::::::::::::::::::::.: ::.:..::. :: ::. .:.::
XP_011 DKVVLHTGKYEELIVCSHEIAASTAQLVAASKVKANKHSPHLSRLQECSRTVNERAANVV
880 890 900 910 920 930
960 970 980 990 1000 1010
pF1KB9 ASTISGKSQIEETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYE
::: ::. :::. :.::::...: ..:.:::..::::::::. :. ::..::::::.::
XP_011 ASTKSGQEQIEDRDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERMRLGELRKQHYV
940 950 960 970 980 990
1020 1030
pF1KB9 LAGVAEGWEEGTEASPPTLQEVVTEKE
:::.. . : . : : . :: :.
XP_011 LAGASGSPGEEVAIRPSTAPRSVTTKKPPLAQKPSVAPRQDHQLDKKDGIYPAQLVNY
1000 1010 1020 1030 1040 1050
>>NP_003950 (OMIM: 605613) huntingtin-interacting protei (1068 aa)
initn: 3279 init1: 1398 opt: 1546 Z-score: 678.8 bits: 137.3 E(85289): 4.5e-31
Smith-Waterman score: 3269; 50.7% identity (77.4% similar) in 1053 aa overlap (6-1037:2-1037)
10 20 30 40 50 60
pF1KB9 MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHA
.:.:.:: .::::: : .::: :::.:..::..::.:::::::. ::::::
NP_003 MNSIKNVPA---RVLSRRP-GHSLEA-EREQFDKTQAISISKAINTQEAPVKEKHA
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 RTCILGTHHEKGAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNE
: :::::::::: :::: . ::: :...: ::::::.::.:::::::::.: :::..
NP_003 RRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNN
. ... .:::: . :::: ..: ::: ::. .: :.:.::..:...:. :..:. .::::
NP_003 IREIGDLWGHLHDRYGQLVNVYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 FFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTV
.::::::::::..:::.: ..:: .:. . .:: ..:::::::::::: :::::: :::
NP_003 IFQLTVEMFDYMDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 KLLFKLHSCLPADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLR
:::::::::::::::::::::: ::: .:...: :.:.. :::::::::.:::.::::::
NP_003 KLLFKLHSCLPADTLQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB9 ASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPF
::::.:::.:::::: :: :..: : ..:...... :.: ..:. :
NP_003 ASALAEHIKPVVVIPEEA--PEDE---EPENLIEISTGPPAGEPVVVADLFDQTFGP-P-
300 310 320 330 340
370 380 390 400 410 420
pF1KB9 NFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQ
:: ::..: :: : ::. :...::..: :.:: . :::..:. ::..: ::.
NP_003 -----NGSVKDDRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQR
350 360 370 380 390
430 440 450 460 470 480
pF1KB9 HLRQQAADDCEFLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQ
. .:.: : : :: :: .:: . . :..: : ::::.:.: ::.:::::.::::.
NP_003 KQKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVH
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB9 NHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQ
::.::::::...::.....:.: .. : :..: ..:... ... : .:. . ::.::.
NP_003 VHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKR
460 470 480 490 500 510
550 560 570 580 590
pF1KB9 ELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEEL---------
:: .. :: : .: . ::... .... : :.:.: ... .:: .:
NP_003 ELEAKAGELARAQEALSHTEQSKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRE
520 530 540 550 560 570
600 610 620 630
pF1KB9 --SALRKELQ-------DTQLKLA---STEESMCQLAKDQRKMLLVGSRKAAEQVIQDAL
.:: .: : . : .:: : :... : :.. .: :. : ..:::.
NP_003 TEAALSREQQRSSQEQGELQGRLAERESQEQGLRQRLLDEQFAVLRGAAAEAAGILQDAV
580 590 600 610 620 630
640 650 660 670 680 690
pF1KB9 NQLEEPPLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLT
..:..: . :..: :.:.: . . . ::.. .:::. : :.:. ..: ..::.
NP_003 SKLDDPLHLRCTSSPDYLVSRAQEALDAVSTLEEGHAQYLTSLADASALVAALTRFSHLA
640 650 660 670 680 690
700 710 720 730 740 750
pF1KB9 SDAIAHGATTCLRAPPEPADSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSK
.:.: .:..: :: .::: : ..:.. : ..: ...:... .:.. ... .:. :.
NP_003 ADTIINGGATSHLAPTDPADRLIDTCRECGARALELMGQLQDQQALRHMQASLVRTPLQG
700 710 720 730 740 750
760 770 780 790 800 810
pF1KB9 IKAIGEELLPRGLDIKQEELGDLVDKEMAATSAAIETATARIEEMLSKSRAGDTGVKLEV
: .:.:: :..::..::::: .::::::::::::: :. :::.:....: ...::::::
NP_003 ILQLGQELKPKSLDVRQEELGAVVDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEV
760 770 780 790 800 810
820 830 840 850 860 870
pF1KB9 NERILGCCTSLMQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAV
:::::. ::.::.::..:...: .::.::::::::.:. .::::::::::::::::::::
NP_003 NERILNSCTDLMKAIRLLVTTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAV
820 830 840 850 860 870
880 890 900 910 920 930
pF1KB9 GWGATVMVDAADLVVQGRGKFEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQAS
::::: .:.::: :: ::.:::.:::::::::::::::::::::.: ::.:..::. :
NP_003 GWGATQLVEAADKVVLHTGKYEELIVCSHEIAASTAQLVAASKVKANKHSPHLSRLQECS
880 890 900 910 920 930
940 950 960 970 980 990
pF1KB9 RGVNQATAGVVASTISGKSQIEETDNMDFSSMTLTQIKRQEMDSQVRVLELENELQKERQ
: ::. .:.::::: ::. :::. :.::::...: ..:.:::..::::::::. :. ::.
NP_003 RTVNERAANVVASTKSGQEQIEDRDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERM
940 950 960 970 980 990
1000 1010 1020 1030
pF1KB9 KLGELRKKHYELAGVAEGWEEGTEASPPTLQEVVTEKE
.::::::.:: :::.. . : . : : . :: :.
NP_003 RLGELRKQHYVLAGASGSPGEEVAIRPSTAPRSVTTKKPPLAQKPSVAPRQDHQLDKKDG
1000 1010 1020 1030 1040 1050
NP_003 IYPAQLVNY
1060
>>NP_001290028 (OMIM: 605613) huntingtin-interacting pro (603 aa)
initn: 1884 init1: 1300 opt: 1479 Z-score: 653.7 bits: 131.8 E(85289): 1.1e-29
Smith-Waterman score: 1844; 50.6% identity (77.5% similar) in 573 aa overlap (42-614:21-581)
20 30 40 50 60 70
pF1KB9 PNPLPKVLSRRGVGAGLEAAERESFERTQTVSINKAINTQEVAVKEKHARTCILGTHHEK
.::.:::::::. ::::::: ::::::::
NP_001 MEARFSPINQILPWCRQDLAISISKAINTQEAPVKEKHARRIILGTHHEK
10 20 30 40 50
80 90 100 110 120 130
pF1KB9 GAQTFWSVVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHL
:: :::: . ::: :...: ::::::.::.:::::::::.: :::... ... .::::
NP_001 GAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPNVLHDCQRYRSNIREIGDLWGHL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB9 SEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDVNNFFQLTVEMFDY
. :::: ..: ::: ::. .: :.:.::..:...:. :..:. .::::.::::::::::
NP_001 HDRYGQLVNVYTKLLLTKISFHLKHPQFPAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDY
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB9 LECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLP
..:::.: ..:: .:. . .:: ..:::::::::::: :::::: ::::::::::::::
NP_001 MDCELKLSESVFRQLNTAIAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLLFKLHSCLP
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB9 ADTLQGHRDRFMEQFTKLKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPV
::::::::::: ::: .:...: :.:.. :::::::::.:::.::::::::::.:::.::
NP_001 ADTLQGHRDRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIKPV
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB9 VVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSDPFNFNSQNGVNKD
:::: :: :..: : ..:...... :.: ..:. : :: ::
NP_001 VVIPEEA--PEDE---EPENLIEISTGPPAGEPVVVADLFDQTFGP-P------NGSVKD
300 310 320 330
380 390 400 410 420 430
pF1KB9 EKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCE
..: :: : ::. :...::..: :.:: . :::..:. ::..: ::.. .:.: : :
NP_001 DRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNE
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB9 FLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAE
:: :: .:: . . :..: : ::::.:.: ::.:::::.::::. ::.::::::.
NP_001 QLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNAD
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB9 VTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQV
..::.....:.: .. : :..: ..:... ... : .:. . ::.::.:: .. ::
NP_001 TAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELAR
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB9 LQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEES
: .: . ::... .... : :.:.: ... .:: .: : .. ...:. :. ..
NP_001 AQEALSHTEQSKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQR
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB9 MCQLAKDQRKMLLVGSRKAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQL
:
NP_001 SSQEQGELQGRLAERVWPPQMQQHH
580 590 600
1037 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:37:24 2016 done: Thu Nov 3 23:37:26 2016
Total Scan time: 15.840 Total Display time: 0.470
Function used was FASTA [36.3.4 Apr, 2011]