Result of FASTA (omim) for
pF1KB9459
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9459, 1224 aa
1>>>pF1KB9459 1224 - 1224 aa - 1224 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4870+/-0.000567; mu= 17.4708+/- 0.035
mean_var=166.3526+/-36.602, 0's: 0 Z-trim(109.8): 267 B-trim: 70 in 1/50
Lambda= 0.099440
statistics sampled from 17752 (18059) to 17752 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.212), width: 16
Scan time: 14.660
The best scores are: opt bits E(85289)
NP_004362 (OMIM: 601924,616414) coatomer subunit a (1224) 8257 1199.0 0
NP_001091868 (OMIM: 601924,616414) coatomer subuni (1233) 4778 699.9 2.6e-200
NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906) 467 81.3 3.2e-14
XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877) 391 70.4 5.9e-11
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 337 62.4 9.3e-09
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 337 62.4 9.9e-09
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 337 62.5 1e-08
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 337 62.5 1.1e-08
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 337 62.5 1.1e-08
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 337 62.5 1.1e-08
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 337 62.5 1.1e-08
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 337 62.5 1.1e-08
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 337 62.5 1.1e-08
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 337 62.5 1.1e-08
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 331 61.6 1.9e-08
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 331 61.6 1.9e-08
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 331 61.6 1.9e-08
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 331 61.6 1.9e-08
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 331 61.6 1.9e-08
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 331 61.6 1.9e-08
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 331 61.6 1.9e-08
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 331 61.6 2e-08
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 331 61.6 2e-08
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 331 61.6 2e-08
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 331 61.6 2e-08
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 326 60.6 2.1e-08
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 325 60.4 2.1e-08
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 325 60.4 2.2e-08
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 325 60.4 2.2e-08
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 326 60.7 2.3e-08
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 326 60.7 2.3e-08
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 326 60.7 2.3e-08
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 326 60.7 2.3e-08
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 325 60.5 2.4e-08
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 326 60.7 2.4e-08
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 326 60.7 2.4e-08
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 326 60.7 2.4e-08
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 325 60.5 2.4e-08
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 325 60.5 2.4e-08
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 322 59.8 2.5e-08
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 322 59.8 2.5e-08
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 322 59.8 2.5e-08
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 325 60.5 2.6e-08
NP_008882 (OMIM: 601787) transcription initiation ( 800) 311 58.9 1.6e-07
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 301 57.1 2.9e-07
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 301 57.2 3.1e-07
NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 279 54.0 2.9e-06
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 279 54.0 2.9e-06
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 268 52.2 5.8e-06
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 268 52.2 5.8e-06
>>NP_004362 (OMIM: 601924,616414) coatomer subunit alpha (1224 aa)
initn: 8257 init1: 8257 opt: 8257 Z-score: 6414.7 bits: 1199.0 E(85289): 0
Smith-Waterman score: 8257; 99.9% identity (99.9% similar) in 1224 aa overlap (1-1224:1-1224)
10 20 30 40 50 60
pF1KB9 MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 KQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 VRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 EVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 SKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 VARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 RTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 FIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 LALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 ALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 KIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 EKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 GTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 GAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 QTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 KFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 QKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 TRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQI
1150 1160 1170 1180 1190 1200
1210 1220
pF1KB9 CRVTTVTEIGKDVIGLRISPLQFR
::::::::::::::::::::::::
NP_004 CRVTTVTEIGKDVIGLRISPLQFR
1210 1220
>>NP_001091868 (OMIM: 601924,616414) coatomer subunit al (1233 aa)
initn: 8243 init1: 4767 opt: 4778 Z-score: 3717.3 bits: 699.9 E(85289): 2.6e-200
Smith-Waterman score: 8229; 99.2% identity (99.2% similar) in 1233 aa overlap (1-1224:1-1233)
10 20 30 40 50 60
pF1KB9 MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 KQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 VRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 EVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 SKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 VARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQK
430 440 450 460 470 480
490 500 510 520 530
pF1KB9 RTLASVKISKVKYVIWSADMSHVALLAKH---------AIVICNRKLDALCNIHENIRVK
::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 RTLASVKISKVKYVIWSADMSHVALLAKHEHSCPLPLTAIVICNRKLDALCNIHENIRVK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB9 SGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB9 IDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB9 ALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB9 NLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB9 ESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGAL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB9 AADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPE
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB9 LDISPGAADGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQ
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQ
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB9 FGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQ
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB9 LCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERK
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB9 KLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLEL
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB9 GPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGAC
1150 1160 1170 1180 1190 1200
1200 1210 1220
pF1KB9 YSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR
:::::::::::::::::::::::::::::::::
NP_001 YSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR
1210 1220 1230
>>NP_004757 (OMIM: 606990) coatomer subunit beta' [Homo (906 aa)
initn: 758 init1: 340 opt: 467 Z-score: 376.4 bits: 81.3 E(85289): 3.2e-14
Smith-Waterman score: 970; 27.3% identity (57.0% similar) in 807 aa overlap (4-765:10-761)
10 20 30 40 50
pF1KB9 MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPV
:. ..: :::....:: .::.:.::.:: . .:... ::. :. : ::
NP_004 MPLRLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 RGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDD
:. : .. :.:.::..:.:.::. . . . .: :::: : :.::..:::
NP_004 RAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 QTIRVWNWQSR-TCVCVLTGHNHYVMCAQFHPTED-LVVSASLDQTVRVWDISGLRKKNL
. :..:.:... .: :. ::.:::: ..: .. .:::::.:..::.. : . :.
NP_004 MLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQL-GSSSPNF
130 140 150 160 170
180 190 200 210 220 230
pF1KB9 SPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHP--TMPLIVSGADDRQVK
. ::::..::: .. : ..:::::: ::
NP_004 T---------------------------LEGHEKGVNCIDYYSGGDKPYLISGADDRLVK
180 190 200 210
240 250 260 270 280 290
pF1KB9 IWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRD
:: .... :.: .:: .::::: :::. .:...::: ..:.: : .:.
NP_004 IWDYQNKTC--VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYG
220 230 240 250 260 270
300 310 320 330 340
pF1KB9 HDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGN-MLHYVKDRFLRQLDFNSS
.: : .:. . : : :.: : :. :: ::.::... .: . ..: ..: ....
NP_004 MERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANGKIIWAKHSEVQQANLKAM
280 290 300 310 320 330
350 360 370 380 390
pF1KB9 KDVAVMQLRSGSKFPVF------------NMSYNPAENAVLLCTRASNLENSTYDLYTIP
:. ....: ..:. ....:: :..: .. : .::
NP_004 GDA---EIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCG------DGEYIIYTAM
340 350 360 370 380
400 410 420 430 440 450
pF1KB9 KDADSQNPDAPEGKRSSGLTAVWVA-RNRFAVLDRMHSLLIKNLKNEITKKVQVPNCD-E
... .: : .:. ...:. : . ..: .:: :: :. :
NP_004 ALRNKSFGSAQE--------FAWAHDSSEYAI--RESNSIVKIFKNFKEKKSFKPDFGAE
390 400 410 420 430
460 470 480 490 500 510
pF1KB9 IFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVIC-
.:.: : .:........: .. . . ..: . :...:: . : . ..... :
NP_004 SIYGGFL-LGVRSVNGLAFYDWDNTELIRRIEI-QPKHIFWSDSGELVCIATEESFFILK
440 450 460 470 480
520 530 540 550
pF1KB9 --NRKLDALCNIHENIR-----------------VKSGAWDESGVFIYTTS-NHIKYAVT
..:. : . ::.. ::.: : . ::::.: :...: :
NP_004 YLSEKVLAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLW-VGDCFIYTSSVNRLNYYVG
490 500 510 520 530 540
560 570 580 590 600
pF1KB9 TGDHGIIRTLDLPIYVTRV--KGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKY---D
:. : :: .:. : : .: :.: .. . .... :.. : . :
NP_004 -GEIVTIAHLDRTMYLLGYIPKDNRLYLGDKELNIISYSLLVSVLEYQTAVMRRDFSMAD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 EVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALD
.:: . : . .:.:.:. . :: : . :: :::. :...:: . : .
NP_004 KVLPTI--PKEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 DKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDM
... :..:.:.:. . . ... : ...... : .: .:: . . :. . ::
NP_004 SEQKWKQLAELAISKCQFGLAQECLHHAQDYGGLLLLATASGNANMVNKLAEGAERDGKN
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 SGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDID
. ... . : :. ...: :. : . : :.
NP_004 NVAFMSYFLQGKVDACLELLIRTGRLPEAAFLARTYLPSQVSRVVKLWRENLSKVNQKAA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 PNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGTEGWGEDA
NP_004 ESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEERNVMEEGKDFQPS
790 800 810 820 830 840
>>XP_016863001 (OMIM: 606990) PREDICTED: coatomer subuni (877 aa)
initn: 682 init1: 264 opt: 391 Z-score: 317.6 bits: 70.4 E(85289): 5.9e-11
Smith-Waterman score: 894; 27.1% identity (56.3% similar) in 787 aa overlap (24-765:1-732)
10 20 30 40 50 60
pF1KB9 MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFH
.:.::.:: . .:... ::. :. : :::. :
XP_016 MLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV
10 20 30
70 80 90 100 110 120
pF1KB9 KQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVW
.. :.:.::..:.:.::. . . . .: :::: : :.::..:::. :..:
XP_016 ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW
40 50 60 70 80 90
130 140 150 160 170
pF1KB9 NWQSR-TCVCVLTGHNHYVMCAQFHPTED-LVVSASLDQTVRVWDISGLRKKNLSPGAVE
.:... .: :. ::.:::: ..: .. .:::::.:..::.. : . :..
XP_016 DWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQL-GSSSPNFT-----
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 SDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHP--TMPLIVSGADDRQVKIWRMNE
::::..::: .. : ..:::::: :::: ...
XP_016 ----------------------LEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQN
160 170 180
240 250 260 270 280 290
pF1KB9 SKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWV
. :.: .:: .::::: :::. .:...::: ..:.: : .:. .: :
XP_016 KTC--VQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWC
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB9 LAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGN-MLHYVKDRFLRQLDFNSSKDVAVM
.:. . : : :.: : :. :: ::.::... .: . ..: ..: .... :.
XP_016 VASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANGKIIWAKHSEVQQANLKAMGDA---
250 260 270 280 290 300
360 370 380 390 400
pF1KB9 QLRSGSKFP--VFNMS----------YNPAENAVLLCTRASNLENSTYDLYTIPKDADSQ
....: ..: : .:. .:: :..: .. : .:: ...
XP_016 EIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCG------DGEYIIYTAMALRNKS
310 320 330 340 350
410 420 430 440 450 460
pF1KB9 NPDAPEGKRSSGLTAVWVA-RNRFAVLDRMHSLLIKNLKNEITKKVQVPNCD-EIFYAGT
.: : .:. ...:. : . ..: .:: :: :. : .:.:
XP_016 FGSAQE--------FAWAHDSSEYAI--RESNSIVKIFKNFKEKKSFKPDFGAESIYGGF
360 370 380 390 400
470 480 490 500 510
pF1KB9 GNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVIC---NRKL
: .:........: .. . . ..: . :...:: . : . ..... : ..:.
XP_016 L-LGVRSVNGLAFYDWDNTELIRRIEI-QPKHIFWSDSGELVCIATEESFFILKYLSEKV
410 420 430 440 450 460
520 530 540 550 560
pF1KB9 DALCNIHENIR-----------------VKSGAWDESGVFIYTTS-NHIKYAVTTGDHGI
: . ::.. ::.: : . ::::.: :...: : :.
XP_016 LAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLW-VGDCFIYTSSVNRLNYYVG-GEIVT
470 480 490 500 510 520
570 580 590 600 610
pF1KB9 IRTLDLPIYVTRV--KGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKY---DEVLHMV
: :: .:. : : .: :.: .. . .... :.. : . :.:: .
XP_016 IAHLDRTMYLLGYIPKDNRLYLGDKELNIISYSLLVSVLEYQTAVMRRDFSMADKVLPTI
530 540 550 560 570 580
620 630 640 650 660 670
pF1KB9 RNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWE
: . .:.:.:. . :: : . :: :::. :...:: . : .... :.
XP_016 --PKEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWK
590 600 610 620 630 640
680 690 700 710 720 730
pF1KB9 KLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQN
.:.:.:. . . ... : ...... : .: .:: . . :. . :: . ...
XP_016 QLAELAISKCQFGLAQECLHHAQDYGGLLLLATASGNANMVNKLAEGAERDGKNNVAFMS
650 660 670 680 690 700
740 750 760 770 780 790
pF1KB9 ALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLL
. : :. ...: :. : . : :.
XP_016 YFLQGKVDACLELLIRTGRLPEAAFLARTYLPSQVSRVVKLWRENLSKVNQKAAESLADP
710 720 730 740 750 760
>>XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD repeat (540 aa)
initn: 439 init1: 106 opt: 337 Z-score: 278.2 bits: 62.4 E(85289): 9.3e-09
Smith-Waterman score: 345; 28.9% identity (57.4% similar) in 263 aa overlap (67-315:228-479)
40 50 60 70 80 90
pF1KB9 DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYI
:::.:: .:::. .:: ::.:: .
XP_011 WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV
200 210 220 230 240 250
100 110 120 130 140 150
pF1KB9 RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLD
.. .. . :.:.: :.:..::: .. :. .: ::. : : ..: : :::.: :
XP_011 WSSQMRDNI--IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRD
260 270 280 290 300 310
160 170 180 190 200
pF1KB9 QTVRVWDISGLRKKNLSPGAVESDVRGIT--GVDLF-GTTDAVVK----------HVLEG
:.::::: . .. : : . :: . : . :. : .:: :.:.:
XP_011 ATLRVWDIETGQCLHVLMGHVAA-VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQG
320 330 340 350 360 370
210 220 230 240 250 260
pF1KB9 HDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQEL
: : : .:::. : ....: .. .. . : :: . .: . ....
XP_011 HTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGMEL--KDNI
380 390 400 410 420
270 280 290 300 310 320
pF1KB9 ILSNSEDKSIRVWDMSKRTGVQTFRR-DHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERE
..:.. :.....::.. .::.. .. . : . : :. .. : : .
XP_011 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT
430 440 450 460 470 480
330 340 350 360 370 380
pF1KB9 RPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTR
XP_011 GEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
490 500 510 520 530 540
>>NP_001013433 (OMIM: 606278) F-box/WD repeat-containing (589 aa)
initn: 439 init1: 106 opt: 337 Z-score: 277.8 bits: 62.4 E(85289): 9.9e-09
Smith-Waterman score: 345; 28.9% identity (57.4% similar) in 263 aa overlap (67-315:277-528)
40 50 60 70 80 90
pF1KB9 DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYI
:::.:: .:::. .:: ::.:: .
NP_001 WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV
250 260 270 280 290 300
100 110 120 130 140 150
pF1KB9 RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLD
.. .. . :.:.: :.:..::: .. :. .: ::. : : ..: : :::.: :
NP_001 WSSQMRDNI--IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRD
310 320 330 340 350 360
160 170 180 190 200
pF1KB9 QTVRVWDISGLRKKNLSPGAVESDVRGIT--GVDLF-GTTDAVVK----------HVLEG
:.::::: . .. : : . :: . : . :. : .:: :.:.:
NP_001 ATLRVWDIETGQCLHVLMGHVAA-VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQG
370 380 390 400 410 420
210 220 230 240 250 260
pF1KB9 HDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQEL
: : : .:::. : ....: .. .. . : :: . .: . ....
NP_001 HTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGMEL--KDNI
430 440 450 460 470
270 280 290 300 310 320
pF1KB9 ILSNSEDKSIRVWDMSKRTGVQTFRR-DHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERE
..:.. :.....::.. .::.. .. . : . : :. .. : : .
NP_001 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT
480 490 500 510 520 530
330 340 350 360 370 380
pF1KB9 RPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTR
NP_001 GEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
540 550 560 570 580
>>NP_060785 (OMIM: 606278) F-box/WD repeat-containing pr (627 aa)
initn: 439 init1: 106 opt: 337 Z-score: 277.4 bits: 62.5 E(85289): 1e-08
Smith-Waterman score: 345; 28.9% identity (57.4% similar) in 263 aa overlap (67-315:315-566)
40 50 60 70 80 90
pF1KB9 DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYI
:::.:: .:::. .:: ::.:: .
NP_060 WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV
290 300 310 320 330 340
100 110 120 130 140 150
pF1KB9 RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLD
.. .. . :.:.: :.:..::: .. :. .: ::. : : ..: : :::.: :
NP_060 WSSQMRDNI--IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRD
350 360 370 380 390 400
160 170 180 190 200
pF1KB9 QTVRVWDISGLRKKNLSPGAVESDVRGIT--GVDLF-GTTDAVVK----------HVLEG
:.::::: . .. : : . :: . : . :. : .:: :.:.:
NP_060 ATLRVWDIETGQCLHVLMGHVAA-VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQG
410 420 430 440 450
210 220 230 240 250 260
pF1KB9 HDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQEL
: : : .:::. : ....: .. .. . : :: . .: . ....
NP_060 HTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGMEL--KDNI
460 470 480 490 500 510
270 280 290 300 310 320
pF1KB9 ILSNSEDKSIRVWDMSKRTGVQTFRR-DHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERE
..:.. :.....::.. .::.. .. . : . : :. .. : : .
NP_060 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT
520 530 540 550 560 570
330 340 350 360 370 380
pF1KB9 RPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTR
NP_060 GEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
580 590 600 610 620
>>XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD repeat (679 aa)
initn: 439 init1: 106 opt: 337 Z-score: 277.0 bits: 62.5 E(85289): 1.1e-08
Smith-Waterman score: 345; 28.9% identity (57.4% similar) in 263 aa overlap (67-315:367-618)
40 50 60 70 80 90
pF1KB9 DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYI
:::.:: .:::. .:: ::.:: .
XP_011 WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV
340 350 360 370 380 390
100 110 120 130 140 150
pF1KB9 RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLD
.. .. . :.:.: :.:..::: .. :. .: ::. : : ..: : :::.: :
XP_011 WSSQMRDNI--IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRD
400 410 420 430 440 450
160 170 180 190 200
pF1KB9 QTVRVWDISGLRKKNLSPGAVESDVRGIT--GVDLF-GTTDAVVK----------HVLEG
:.::::: . .. : : . :: . : . :. : .:: :.:.:
XP_011 ATLRVWDIETGQCLHVLMGHVAA-VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQG
460 470 480 490 500 510
210 220 230 240 250 260
pF1KB9 HDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQEL
: : : .:::. : ....: .. .. . : :: . .: . ....
XP_011 HTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGMEL--KDNI
520 530 540 550 560
270 280 290 300 310 320
pF1KB9 ILSNSEDKSIRVWDMSKRTGVQTFRR-DHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERE
..:.. :.....::.. .::.. .. . : . : :. .. : : .
XP_011 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT
570 580 590 600 610 620
330 340 350 360 370 380
pF1KB9 RPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTR
XP_011 GEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
630 640 650 660 670
>>XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD repeat (679 aa)
initn: 439 init1: 106 opt: 337 Z-score: 277.0 bits: 62.5 E(85289): 1.1e-08
Smith-Waterman score: 345; 28.9% identity (57.4% similar) in 263 aa overlap (67-315:367-618)
40 50 60 70 80 90
pF1KB9 DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYI
:::.:: .:::. .:: ::.:: .
XP_011 WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV
340 350 360 370 380 390
100 110 120 130 140 150
pF1KB9 RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLD
.. .. . :.:.: :.:..::: .. :. .: ::. : : ..: : :::.: :
XP_011 WSSQMRDNI--IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRD
400 410 420 430 440 450
160 170 180 190 200
pF1KB9 QTVRVWDISGLRKKNLSPGAVESDVRGIT--GVDLF-GTTDAVVK----------HVLEG
:.::::: . .. : : . :: . : . :. : .:: :.:.:
XP_011 ATLRVWDIETGQCLHVLMGHVAA-VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQG
460 470 480 490 500 510
210 220 230 240 250 260
pF1KB9 HDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQEL
: : : .:::. : ....: .. .. . : :: . .: . ....
XP_011 HTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGMEL--KDNI
520 530 540 550 560
270 280 290 300 310 320
pF1KB9 ILSNSEDKSIRVWDMSKRTGVQTFRR-DHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERE
..:.. :.....::.. .::.. .. . : . : :. .. : : .
XP_011 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT
570 580 590 600 610 620
330 340 350 360 370 380
pF1KB9 RPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTR
XP_011 GEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
630 640 650 660 670
>>NP_361014 (OMIM: 606278) F-box/WD repeat-containing pr (707 aa)
initn: 439 init1: 106 opt: 337 Z-score: 276.8 bits: 62.5 E(85289): 1.1e-08
Smith-Waterman score: 345; 28.9% identity (57.4% similar) in 263 aa overlap (67-315:395-646)
40 50 60 70 80 90
pF1KB9 DYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYI
:::.:: .:::. .:: ::.:: .
NP_361 WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV
370 380 390 400 410 420
100 110 120 130 140 150
pF1KB9 RTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLD
.. .. . :.:.: :.:..::: .. :. .: ::. : : ..: : :::.: :
NP_361 WSSQMRDNI--IISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRD
430 440 450 460 470 480
160 170 180 190 200
pF1KB9 QTVRVWDISGLRKKNLSPGAVESDVRGIT--GVDLF-GTTDAVVK----------HVLEG
:.::::: . .. : : . :: . : . :. : .:: :.:.:
NP_361 ATLRVWDIETGQCLHVLMGHVAA-VRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQG
490 500 510 520 530
210 220 230 240 250 260
pF1KB9 HDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQEL
: : : .:::. : ....: .. .. . : :: . .: . ....
NP_361 HTNRVYSLQFDGIH--VVSGSLDTSIRVWDVETGNC--IHTLTGHQSLTSGMEL--KDNI
540 550 560 570 580 590
270 280 290 300 310 320
pF1KB9 ILSNSEDKSIRVWDMSKRTGVQTFRR-DHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERE
..:.. :.....::.. .::.. .. . : . : :. .. : : .
NP_361 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKT
600 610 620 630 640 650
330 340 350 360 370 380
pF1KB9 RPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTR
NP_361 GEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
660 670 680 690 700
1224 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:31:45 2016 done: Thu Nov 3 23:31:47 2016
Total Scan time: 14.660 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]