Result of FASTA (omim) for
pF1KB9456
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9456, 1150 aa
1>>>pF1KB9456 1150 - 1150 aa - 1150 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3357+/-0.000488; mu= 17.0911+/- 0.030
mean_var=90.3525+/-18.223, 0's: 0 Z-trim(109.8): 58 B-trim: 90 in 1/53
Lambda= 0.134929
statistics sampled from 17976 (18033) to 17976 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.546), E-opt: 0.2 (0.211), width: 16
Scan time: 12.670
The best scores are: opt bits E(85289)
NP_598408 (OMIM: 218000,604878) solute carrier fam (1150) 7552 1481.5 0
NP_001035961 (OMIM: 218000,604878) solute carrier (1141) 7488 1469.0 0
NP_001035959 (OMIM: 218000,604878) solute carrier (1091) 7172 1407.5 0
NP_001035960 (OMIM: 218000,604878) solute carrier (1091) 7172 1407.5 0
NP_005126 (OMIM: 218000,604878) solute carrier fam (1099) 6989 1371.9 0
NP_001035962 (OMIM: 218000,604878) solute carrier (1135) 6899 1354.4 0
XP_006720856 (OMIM: 218000,604878) PREDICTED: solu (1101) 6038 1186.7 0
NP_005063 (OMIM: 604119) solute carrier family 12 (1085) 5563 1094.3 0
NP_001139435 (OMIM: 604119) solute carrier family (1079) 5540 1089.8 0
NP_001139436 (OMIM: 604119) solute carrier family (1054) 5538 1089.4 0
NP_001139433 (OMIM: 604119) solute carrier family (1079) 5507 1083.4 0
NP_001139434 (OMIM: 604119) solute carrier family (1087) 5459 1074.0 0
NP_006589 (OMIM: 604879) solute carrier family 12 (1083) 5044 993.2 0
XP_011512243 (OMIM: 604879) PREDICTED: solute carr (1111) 5035 991.5 0
XP_011512241 (OMIM: 604879) PREDICTED: solute carr (1085) 5030 990.5 0
XP_011512242 (OMIM: 604879) PREDICTED: solute carr (1074) 5024 989.4 0
XP_005248288 (OMIM: 604879) PREDICTED: solute carr (1088) 5024 989.4 0
XP_016864448 (OMIM: 604879) PREDICTED: solute carr (1020) 4972 979.2 0
XP_016864447 (OMIM: 604879) PREDICTED: solute carr (1020) 4972 979.2 0
XP_016883470 (OMIM: 606726,616645,616685) PREDICTE (1134) 4707 927.7 0
NP_001128243 (OMIM: 606726,616645,616685) solute c (1139) 4707 927.7 0
NP_065759 (OMIM: 606726,616645,616685) solute carr (1116) 4699 926.1 0
XP_011520571 (OMIM: 218000,604878) PREDICTED: solu ( 680) 4451 877.7 0
XP_006716117 (OMIM: 616861) PREDICTED: solute carr ( 825) 669 141.5 2e-32
XP_005250559 (OMIM: 616861) PREDICTED: solute carr ( 825) 669 141.5 2e-32
XP_011514716 (OMIM: 616861) PREDICTED: solute carr ( 722) 658 139.4 7.8e-32
NP_001254743 (OMIM: 616861) solute carrier family ( 538) 617 131.3 1.5e-29
XP_016865260 (OMIM: 600840) PREDICTED: solute carr ( 626) 610 130.0 4.5e-29
NP_001243390 (OMIM: 600840) solute carrier family (1196) 610 130.1 7.8e-29
NP_001037 (OMIM: 600840) solute carrier family 12 (1212) 610 130.1 7.9e-29
XP_005254663 (OMIM: 600839,601678) PREDICTED: solu (1099) 588 125.8 1.4e-27
NP_000329 (OMIM: 600839,601678) solute carrier fam (1099) 588 125.8 1.4e-27
NP_001119579 (OMIM: 263800,600968) solute carrier (1029) 587 125.6 1.5e-27
NP_000330 (OMIM: 263800,600968) solute carrier fam (1030) 587 125.6 1.5e-27
XP_005256176 (OMIM: 263800,600968) PREDICTED: solu (1020) 559 120.2 6.6e-26
NP_001119580 (OMIM: 263800,600968) solute carrier (1021) 559 120.2 6.6e-26
XP_005250561 (OMIM: 616861) PREDICTED: solute carr ( 556) 489 106.4 5e-22
XP_011541890 (OMIM: 600840) PREDICTED: solute carr ( 628) 391 87.4 3.1e-16
NP_001171761 (OMIM: 600839,601678) solute carrier (1099) 383 85.9 1.5e-15
NP_001254741 (OMIM: 616861) solute carrier family ( 631) 361 81.5 1.8e-14
NP_064631 (OMIM: 616861) solute carrier family 12 ( 914) 361 81.6 2.4e-14
XP_006716118 (OMIM: 616861) PREDICTED: solute carr ( 811) 360 81.4 2.5e-14
NP_001182412 (OMIM: 611316) solute carrier family ( 714) 279 65.6 1.3e-09
NP_078904 (OMIM: 611316) solute carrier family 12 ( 714) 279 65.6 1.3e-09
NP_001253966 (OMIM: 604235) large neutral amino ac ( 311) 181 46.4 0.00034
XP_016869236 (OMIM: 601872) PREDICTED: cationic am ( 657) 174 45.1 0.0017
NP_003037 (OMIM: 601872) cationic amino acid trans ( 697) 174 45.2 0.0017
NP_877392 (OMIM: 604235) large neutral amino acids ( 332) 169 44.0 0.0018
XP_005273667 (OMIM: 601872) PREDICTED: cationic am ( 658) 169 44.2 0.0033
XP_005273668 (OMIM: 601872) PREDICTED: cationic am ( 658) 169 44.2 0.0033
>>NP_598408 (OMIM: 218000,604878) solute carrier family (1150 aa)
initn: 7552 init1: 7552 opt: 7552 Z-score: 7942.1 bits: 1481.5 E(85289): 0
Smith-Waterman score: 7552; 100.0% identity (100.0% similar) in 1150 aa overlap (1-1150:1-1150)
10 20 30 40 50 60
pF1KB9 MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 SEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 KTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
1090 1100 1110 1120 1130 1140
1150
pF1KB9 GGSEVITIYS
::::::::::
NP_598 GGSEVITIYS
1150
>>NP_001035961 (OMIM: 218000,604878) solute carrier fami (1141 aa)
initn: 7488 init1: 7488 opt: 7488 Z-score: 7874.8 bits: 1469.0 E(85289): 0
Smith-Waterman score: 7488; 100.0% identity (100.0% similar) in 1141 aa overlap (10-1150:1-1141)
10 20 30 40 50 60
pF1KB9 MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 SEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB9 KTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB9 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB9 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB9 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB9 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB9 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB9 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB9 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB9 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB9 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB9 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB9 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB9 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB9 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB9 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB9 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
1080 1090 1100 1110 1120 1130
1150
pF1KB9 GGSEVITIYS
::::::::::
NP_001 GGSEVITIYS
1140
>>NP_001035959 (OMIM: 218000,604878) solute carrier fami (1091 aa)
initn: 7172 init1: 7172 opt: 7172 Z-score: 7542.7 bits: 1407.5 E(85289): 0
Smith-Waterman score: 7172; 100.0% identity (100.0% similar) in 1091 aa overlap (60-1150:1-1091)
30 40 50 60 70 80
pF1KB9 DTSPDLSSRSSSRVRFSSRESVPETSRSEPMSEMSGATTSLATVALDPPSDRTSHPQDVI
::::::::::::::::::::::::::::::
NP_001 MSEMSGATTSLATVALDPPSDRTSHPQDVI
10 20 30
90 100 110 120 130 140
pF1KB9 EDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB9 LNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLT
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB9 WVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVG
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB9 LCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLM
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB9 VLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDV
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB9 CSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB9 NYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDL
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB9 KDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP
460 470 480 490 500 510
570 580 590 600 610 620
pF1KB9 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAI
520 530 540 550 560 570
630 640 650 660 670 680
pF1KB9 AELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMS
580 590 600 610 620 630
690 700 710 720 730 740
pF1KB9 ICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGP
640 650 660 670 680 690
750 760 770 780 790 800
pF1KB9 PHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALA
700 710 720 730 740 750
810 820 830 840 850 860
pF1KB9 AEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSED
760 770 780 790 800 810
870 880 890 900 910 920
pF1KB9 ARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFL
820 830 840 850 860 870
930 940 950 960 970 980
pF1KB9 LKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYE
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KB9 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KB9 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150
pF1KB9 GPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
:::::::::::::::::::::::::::::::::::::::::
NP_001 GPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
1060 1070 1080 1090
>>NP_001035960 (OMIM: 218000,604878) solute carrier fami (1091 aa)
initn: 7172 init1: 7172 opt: 7172 Z-score: 7542.7 bits: 1407.5 E(85289): 0
Smith-Waterman score: 7172; 100.0% identity (100.0% similar) in 1091 aa overlap (60-1150:1-1091)
30 40 50 60 70 80
pF1KB9 DTSPDLSSRSSSRVRFSSRESVPETSRSEPMSEMSGATTSLATVALDPPSDRTSHPQDVI
::::::::::::::::::::::::::::::
NP_001 MSEMSGATTSLATVALDPPSDRTSHPQDVI
10 20 30
90 100 110 120 130 140
pF1KB9 EDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB9 LNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLT
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB9 WVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVG
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB9 LCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLM
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB9 VLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDV
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB9 CSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB9 NYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDL
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB9 KDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSP
460 470 480 490 500 510
570 580 590 600 610 620
pF1KB9 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAI
520 530 540 550 560 570
630 640 650 660 670 680
pF1KB9 AELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMS
580 590 600 610 620 630
690 700 710 720 730 740
pF1KB9 ICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGP
640 650 660 670 680 690
750 760 770 780 790 800
pF1KB9 PHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALA
700 710 720 730 740 750
810 820 830 840 850 860
pF1KB9 AEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSED
760 770 780 790 800 810
870 880 890 900 910 920
pF1KB9 ARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFL
820 830 840 850 860 870
930 940 950 960 970 980
pF1KB9 LKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYE
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KB9 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTW
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KB9 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMP
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150
pF1KB9 GPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
:::::::::::::::::::::::::::::::::::::::::
NP_001 GPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
1060 1070 1080 1090
>>NP_005126 (OMIM: 218000,604878) solute carrier family (1099 aa)
initn: 6975 init1: 6975 opt: 6989 Z-score: 7350.1 bits: 1371.9 E(85289): 0
Smith-Waterman score: 6989; 98.5% identity (99.2% similar) in 1082 aa overlap (71-1150:18-1099)
50 60 70 80 90
pF1KB9 SRVRFSSRESVPETSRSEPMSEMSGATTSLATVALDPP-SDRTSHPQDVIE-DLSQNSIT
:... .: .: .. :: : ::::::::
NP_005 MPHFTVTKVEDPEEGAAASISQEPSLADIKARIQDSDEPDLSQNSIT
10 20 30 40
100 110 120 130 140 150
pF1KB9 GEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTN
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB9 LTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVL
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 QAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTF
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB9 AAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVR
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB9 YVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINN
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB9 MTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEII
350 360 370 380 390 400
460 470 480 490 500 510
pF1KB9 EKPSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKPSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPI
410 420 430 440 450 460
520 530 540 550 560 570
pF1KB9 GTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFF
470 480 490 500 510 520
580 590 600 610 620 630
pF1KB9 STCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIAS
530 540 550 560 570 580
640 650 660 670 680 690
pF1KB9 LDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFIS
590 600 610 620 630 640
700 710 720 730 740 750
pF1KB9 SWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQ
650 660 670 680 690 700
760 770 780 790 800 810
pF1KB9 LLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLM
710 720 730 740 750 760
820 830 840 850 860 870
pF1KB9 EAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIG
770 780 790 800 810 820
880 890 900 910 920 930
pF1KB9 TVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRK
830 840 850 860 870 880
940 950 960 970 980 990
pF1KB9 CSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRS
890 900 910 920 930 940
1000 1010 1020 1030 1040 1050
pF1KB9 QMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASR
950 960 970 980 990 1000
1060 1070 1080 1090 1100 1110
pF1KB9 GQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGD
1010 1020 1030 1040 1050 1060
1120 1130 1140 1150
pF1KB9 ENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
::::::::::::::::::::::::::::::::
NP_005 ENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
1070 1080 1090
>>NP_001035962 (OMIM: 218000,604878) solute carrier fami (1135 aa)
initn: 6882 init1: 6882 opt: 6899 Z-score: 7255.2 bits: 1354.4 E(85289): 0
Smith-Waterman score: 7419; 98.7% identity (98.7% similar) in 1150 aa overlap (1-1150:1-1135)
10 20 30 40 50 60
pF1KB9 MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNS
::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 SEMSGATTSLATVALDPPSDRTSHPQDVIED---------------DGHKKARNAYLNNS
70 80 90 100
130 140 150 160 170 180
pF1KB9 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 KTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB9 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB9 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB9 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB9 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB9 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB9 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
710 720 730 740 750 760
790 800 810 820 830 840
pF1KB9 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB9 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
830 840 850 860 870 880
910 920 930 940 950 960
pF1KB9 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KB9 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KB9 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KB9 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
1070 1080 1090 1100 1110 1120
1150
pF1KB9 GGSEVITIYS
::::::::::
NP_001 GGSEVITIYS
1130
>>XP_006720856 (OMIM: 218000,604878) PREDICTED: solute c (1101 aa)
initn: 6038 init1: 6038 opt: 6038 Z-score: 6349.6 bits: 1186.7 E(85289): 0
Smith-Waterman score: 7095; 95.7% identity (95.7% similar) in 1150 aa overlap (1-1150:1-1101)
10 20 30 40 50 60
pF1KB9 MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSA
:: :::::::::
XP_006 KT-------------------------------------------------MLTAISMSA
190
250 260 270 280 290 300
pF1KB9 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB9 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYA
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB9 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATC
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB9 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVD
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB9 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGA
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB9 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAK
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB9 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA
560 570 580 590 600 610
670 680 690 700 710 720
pF1KB9 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQ
620 630 640 650 660 670
730 740 750 760 770 780
pF1KB9 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFA
680 690 700 710 720 730
790 800 810 820 830 840
pF1KB9 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGIS
740 750 760 770 780 790
850 860 870 880 890 900
pF1KB9 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFP
800 810 820 830 840 850
910 920 930 940 950 960
pF1KB9 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDL
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KB9 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKD
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KB9 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSN
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KB9 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRG
1040 1050 1060 1070 1080 1090
1150
pF1KB9 GGSEVITIYS
::::::::::
XP_006 GGSEVITIYS
1100
>>NP_005063 (OMIM: 604119) solute carrier family 12 memb (1085 aa)
initn: 5528 init1: 3874 opt: 5563 Z-score: 5850.0 bits: 1094.3 E(85289): 0
Smith-Waterman score: 5563; 76.8% identity (91.2% similar) in 1087 aa overlap (70-1150:4-1085)
40 50 60 70 80 90
pF1KB9 SSRVRFSSRESVPETSRSEPMSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITG
...: .: : : .. : .: :: . :
NP_005 MPHFTVVPVDGPR-RGDY--DNLEGLSWVDY-G
10 20
100 110 120 130 140 150
pF1KB9 EHSQLLD-DGHKKARNA--YLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANY
:...: : ::: . :.. .:. . .: .:.:.::::::::.: ::::::::.....:
NP_005 ERAELDDSDGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSY
30 40 50 60 70 80
160 170 180 190 200 210
pF1KB9 TNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAG
::::::::::::::. ... ...:.:::.::::::::::::::::::::::.:::::
NP_005 TNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAG
90 100 110 120 130 140
220 230 240 250 260 270
pF1KB9 VLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGT
::::. :::::::::.::::::::::::::::::::::::::.:::::::::::::::::
NP_005 VLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGT
150 160 170 180 190 200
280 290 300 310 320 330
pF1KB9 TFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIG
::::::::::::::.:.::.: ::::. . : : : ::::::::: ::..:.::::.:
NP_005 TFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVG
210 220 230 240 250 260
340 350 360 370 380 390
pF1KB9 VRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEI
:.::::::::::::::.:::.::::.::: : :: :::::::::::: ..:.:.:: .
NP_005 VKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVV
270 280 290 300 310 320
400 410 420 430 440 450
pF1KB9 NNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGE
.: :: ..::.:::.: .. . .:: ::. :::: : :::: :.:.. ::::: :: ::.
NP_005 DNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGD
330 340 350 360 370 380
460 470 480 490 500 510
pF1KB9 IIEK---PSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQ
:.:: ::: . .. :: ::..::.::::.::::::::::::::::::::::.:::
NP_005 IVEKHGLPSADAPSLKESLPL-YVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQ
390 400 410 420 430 440
520 530 540 550 560 570
pF1KB9 KSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIV
::::.::::::.:::.::.:.::::::::::::::::.::.:. :::::::.::::::::
NP_005 KSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIV
450 460 470 480 490 500
580 590 600 610 620 630
pF1KB9 IGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELG
:::::::::::::::::::::::::::::::::::::::.:.:::::::::::: :::::
NP_005 IGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELG
510 520 530 540 550 560
640 650 660 670 680 690
pF1KB9 ILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLA
:::::::.:::::::::::::::::::::.:::::::::::::.::::::::.:::.:::
NP_005 ILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLA
570 580 590 600 610 620
700 710 720 730 740 750
pF1KB9 LMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTK
:::.::::::.:::.:::::::::::::::::::::::::::::::.:::::::::::::
NP_005 LMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTK
630 640 650 660 670 680
760 770 780 790 800 810
pF1KB9 NWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQT
:::::::::::::::::::.::::::::::::::::::::::: :.:::.:::: :::::
NP_005 NWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQT
690 700 710 720 730 740
820 830 840 850 860 870
pF1KB9 IKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAW
::..:: ::::::::.:::.:.:::..:::::::::::.::.::.::: ::::::: :::
NP_005 IKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAW
750 760 770 780 790 800
880 890 900 910 920 930
pF1KB9 KTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQH
:::: ::: :::::::::: :::.:.::: :.. ::.::::::::::::::::::::.::
NP_005 KTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQH
810 820 830 840 850 860
940 950 960 970 980 990
pF1KB9 KVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLM
:::::: .:::::::..:::::::::::.::::::.::::::::::.:::::::::::::
NP_005 KVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLM
870 880 890 900 910 920
1000 1010 1020 1030 1040 1050
pF1KB9 MEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDK
:::::::::.:::.::::.:::::::::.: ::: :. :::..:. . .:..::::.::
NP_005 MEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDK
930 940 950 960 970 980
1060 1070 1080 1090 1100 1110
pF1KB9 YMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPR
::. . ... ..:..:....::::::::::::::::::::..::.:.:::::::::::
NP_005 YMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPR
990 1000 1010 1020 1030 1040
1120 1130 1140 1150
pF1KB9 NPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
: ::::::::::::::::::::::::::: :::::::
NP_005 NSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS
1050 1060 1070 1080
>>NP_001139435 (OMIM: 604119) solute carrier family 12 m (1079 aa)
initn: 5528 init1: 3874 opt: 5540 Z-score: 5825.9 bits: 1089.8 E(85289): 0
Smith-Waterman score: 5540; 78.1% identity (92.0% similar) in 1052 aa overlap (102-1150:29-1079)
80 90 100 110 120 130
pF1KB9 TVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDK
: : :... . .:. . .: .:.:.
NP_001 MAAEGAVCGFVYLEGTAWAVPEDTEPLASCTLGHGNHRESSPFLSPLEASRGIDYYDR
10 20 30 40 50
140 150 160 170 180 190
pF1KB9 NLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGV
::::::::.: ::::::::.....:::::::::::::::. ... ...:.:::.:::
NP_001 NLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGV
60 70 80 90 100 110
200 210 220 230 240 250
pF1KB9 YLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGG
:::::::::::::::::::.:::::::::. :::::::::.:::::::::::::::::::
NP_001 YLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGG
120 130 140 150 160 170
260 270 280 290 300 310
pF1KB9 SYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKES
:::::::.:::::::::::::::::::::::::::::::.:.::.: ::::. . : :
NP_001 SYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTS
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB9 AAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPH
: ::::::::: ::..:.::::.::.::::::::::::::.:::.::::.::: : ::
NP_001 NATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPV
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB9 FPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTS
:::::::::::: ..:.:.:: ..: :: ..::.:::.: .. . .:: ::. ::::
NP_001 FPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTE
300 310 320 330 340 350
440 450 460 470 480
pF1KB9 IQGIPGLASGIITENLWSNYLPKGEIIEK---PSAKSSDVLGSLNHEYVLVDITTSFTLL
: :::: :.:.. ::::: :: ::.:.:: ::: . .. :: ::..::.::::.:
NP_001 IPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPL-YVVADIATSFTVL
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB9 VGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLR
:::::::::::::::::::::.:::::::.::::::.:::.::.:.::::::::::::::
NP_001 VGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLR
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB9 DKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR
::.::.:. :::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 DKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLR
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB9 VFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLR
::::.:.:::::::::::: ::::::::::::.:::::::::::::::::::::.:::::
NP_001 VFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLR
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB9 TPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGD
::::::::.::::::::.:::.::::::.::::::.:::.::::::::::::::::::::
NP_001 TPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGD
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB9 GIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKG
:::::::::::.::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 GIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKG
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB9 LTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGL
:::::::: :.:::.:::: :::::::..:: ::::::::.:::.:.:::..::::::::
NP_001 LTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGL
720 730 740 750 760 770
850 860 870 880 890 900
pF1KB9 GGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSE
:::.::.::.::: ::::::: ::::::: ::: :::::::::: :::.:.::: :.. :
NP_001 GGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLE
780 790 800 810 820 830
910 920 930 940 950 960
pF1KB9 GNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLR
:.::::::::::::::::::::.:::::::: .:::::::..:::::::::::.::::::
NP_001 GHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLR
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KB9 IEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLT
.::::::::::.::::::::::::::::::::::.:::.::::.:::::::::.: :::
NP_001 LEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLE
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KB9 SIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAV
:. :::..:. . .:..::::.::::. . ... ..:..:....:::::::::::::
NP_001 SLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAV
960 970 980 990 1000 1010
1090 1100 1110 1120 1130 1140
pF1KB9 KLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITI
:::::::..::.:.:::::::::::: ::::::::::::::::::::::::::: :::::
NP_001 KLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITI
1020 1030 1040 1050 1060 1070
1150
pF1KB9 YS
::
NP_001 YS
>>NP_001139436 (OMIM: 604119) solute carrier family 12 m (1054 aa)
initn: 5528 init1: 3874 opt: 5538 Z-score: 5823.9 bits: 1089.4 E(85289): 0
Smith-Waterman score: 5538; 78.3% identity (92.2% similar) in 1051 aa overlap (105-1150:5-1054)
80 90 100 110 120 130
pF1KB9 LDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNA--YLNNSNYEEGDEYFDKN
:. :: . :.. .:. . .: .:.:.:
NP_001 MGDTLSPGHGNHRESSPFLSPLEASRGIDYYDRN
10 20 30
140 150 160 170 180 190
pF1KB9 LALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVY
:::::::.: ::::::::.....:::::::::::::::. ... ...:.:::.::::
NP_001 LALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVY
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB9 LPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGS
::::::::::::::::::.:::::::::. :::::::::.::::::::::::::::::::
NP_001 LPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB9 YFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESA
::::::.:::::::::::::::::::::::::::::::.:.::.: ::::. . : :
NP_001 YFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSN
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB9 AMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHF
: ::::::::: ::..:.::::.::.::::::::::::::.:::.::::.::: : :: :
NP_001 ATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVF
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB9 PVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSI
::::::::::: ..:.:.:: ..: :: ..::.:::.: .. . .:: ::. :::: :
NP_001 PVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEI
280 290 300 310 320 330
440 450 460 470 480
pF1KB9 QGIPGLASGIITENLWSNYLPKGEIIEK---PSAKSSDVLGSLNHEYVLVDITTSFTLLV
:::: :.:.. ::::: :: ::.:.:: ::: . .. :: ::..::.::::.::
NP_001 PGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPL-YVVADIATSFTVLV
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB9 GIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRD
::::::::::::::::::::.:::::::.::::::.:::.::.:.:::::::::::::::
NP_001 GIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRD
400 410 420 430 440 450
550 560 570 580 590 600
pF1KB9 KFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRV
:.::.:. :::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRV
460 470 480 490 500 510
610 620 630 640 650 660
pF1KB9 FGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRT
:::.:.:::::::::::: ::::::::::::.:::::::::::::::::::::.::::::
NP_001 FGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRT
520 530 540 550 560 570
670 680 690 700 710 720
pF1KB9 PNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDG
:::::::.::::::::.:::.::::::.::::::.:::.:::::::::::::::::::::
NP_001 PNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDG
580 590 600 610 620 630
730 740 750 760 770 780
pF1KB9 IRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGL
::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::::
NP_001 IRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGL
640 650 660 670 680 690
790 800 810 820 830 840
pF1KB9 TIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLG
::::::: :.:::.:::: :::::::..:: ::::::::.:::.:.:::..:::::::::
NP_001 TIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLG
700 710 720 730 740 750
850 860 870 880 890 900
pF1KB9 GMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEG
::.::.::.::: ::::::: ::::::: ::: :::::::::: :::.:.::: :.. ::
NP_001 GMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEG
760 770 780 790 800 810
910 920 930 940 950 960
pF1KB9 NIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRI
.::::::::::::::::::::.:::::::: .:::::::..:::::::::::.::::::.
NP_001 HIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRL
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KB9 EAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTS
::::::::::.::::::::::::::::::::::.:::.::::.:::::::::.: ::: :
NP_001 EAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLES
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KB9 IGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVK
. :::..:. . .:..::::.::::. . ... ..:..:....::::::::::::::
NP_001 LYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVK
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KB9 LNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIY
::::::..::.:.:::::::::::: ::::::::::::::::::::::::::: ::::::
NP_001 LNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIY
1000 1010 1020 1030 1040 1050
1150
pF1KB9 S
:
NP_001 S
1150 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:28:48 2016 done: Thu Nov 3 23:28:50 2016
Total Scan time: 12.670 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]