FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9279, 311 aa 1>>>pF1KB9279 311 - 311 aa - 311 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9067+/-0.000422; mu= 17.4273+/- 0.026 mean_var=66.8676+/-13.513, 0's: 0 Z-trim(110.1): 234 B-trim: 750 in 1/50 Lambda= 0.156843 statistics sampled from 18143 (18408) to 18143 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.216), width: 16 Scan time: 6.930 The best scores are: opt bits E(85289) NP_001098117 (OMIM: 616149) solute carrier family ( 311) 1998 461.4 1.1e-129 NP_060625 (OMIM: 616149) solute carrier family 25 ( 310) 1980 457.3 1.8e-128 NP_115691 (OMIM: 610816) solute carrier family 25 ( 321) 1240 289.9 4.6e-78 XP_005247632 (OMIM: 616149) PREDICTED: solute carr ( 204) 1162 272.1 6.7e-73 XP_011540598 (OMIM: 610816) PREDICTED: solute carr ( 258) 1016 239.1 7.1e-63 XP_005263560 (OMIM: 610816) PREDICTED: solute carr ( 254) 986 232.3 7.8e-61 NP_110407 (OMIM: 610815,616839) mitochondrial fola ( 315) 416 103.4 6.1e-22 XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 346 87.5 3.2e-17 NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 346 87.5 3.2e-17 XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 346 87.5 3.2e-17 XP_006716415 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 346 87.5 3.2e-17 NP_001304743 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 346 87.5 3.2e-17 XP_011542852 (OMIM: 610387) PREDICTED: mitoferrin- ( 272) 346 87.5 3.2e-17 NP_057696 (OMIM: 610387) mitoferrin-1 isoform 1 [H ( 338) 346 87.6 3.8e-17 XP_011538513 (OMIM: 139080) PREDICTED: graves dise ( 332) 305 78.3 2.3e-14 NP_689920 (OMIM: 139080) graves disease carrier pr ( 332) 305 78.3 2.3e-14 XP_016869366 (OMIM: 610815,616839) PREDICTED: mito ( 183) 296 76.1 6e-14 NP_077008 (OMIM: 608746) calcium-binding mitochond ( 468) 296 76.4 1.2e-13 XP_011526583 (OMIM: 608746) PREDICTED: calcium-bin ( 515) 296 76.4 1.3e-13 XP_011526580 (OMIM: 608746) PREDICTED: calcium-bin ( 549) 296 76.5 1.4e-13 XP_011526579 (OMIM: 608746) PREDICTED: calcium-bin ( 560) 296 76.5 1.4e-13 XP_016882774 (OMIM: 608746) PREDICTED: calcium-bin ( 562) 296 76.5 1.4e-13 XP_011526577 (OMIM: 608746) PREDICTED: calcium-bin ( 577) 296 76.5 1.5e-13 XP_011526576 (OMIM: 608746) PREDICTED: calcium-bin ( 624) 296 76.5 1.5e-13 XP_005251746 (OMIM: 608745) PREDICTED: calcium-bin ( 366) 293 75.6 1.6e-13 XP_006717012 (OMIM: 608745) PREDICTED: calcium-bin ( 378) 293 75.7 1.7e-13 NP_443133 (OMIM: 608745) calcium-binding mitochond ( 469) 293 75.7 2e-13 XP_006717011 (OMIM: 608745) PREDICTED: calcium-bin ( 481) 293 75.7 2e-13 NP_001006643 (OMIM: 608745) calcium-binding mitoch ( 489) 293 75.7 2.1e-13 NP_001252543 (OMIM: 608745) calcium-binding mitoch ( 501) 293 75.7 2.1e-13 NP_001006642 (OMIM: 608745) calcium-binding mitoch ( 503) 293 75.7 2.1e-13 NP_001317917 (OMIM: 608745) calcium-binding mitoch ( 515) 293 75.8 2.1e-13 XP_016856593 (OMIM: 608744) PREDICTED: calcium-bin ( 271) 289 74.6 2.4e-13 NP_998816 (OMIM: 608744) calcium-binding mitochond ( 458) 289 74.8 3.7e-13 NP_037518 (OMIM: 608744) calcium-binding mitochond ( 477) 289 74.8 3.8e-13 XP_016864579 (OMIM: 616150) PREDICTED: solute carr ( 257) 282 73.0 7e-13 XP_016864576 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13 XP_006714609 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13 XP_016864575 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13 XP_016864577 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13 XP_011535589 (OMIM: 607571) PREDICTED: mitochondri ( 303) 272 70.8 3.8e-12 NP_112581 (OMIM: 610796) ADP/ATP translocase 4 iso ( 315) 270 70.4 5.4e-12 XP_011535590 (OMIM: 607571) PREDICTED: mitochondri ( 269) 267 69.7 7.7e-12 NP_001164641 (OMIM: 607571) mitochondrial 2-oxodic ( 298) 267 69.7 8.3e-12 NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarb ( 299) 267 69.7 8.3e-12 NP_001311243 (OMIM: 139080) graves disease carrier ( 234) 257 67.3 3.3e-11 NP_001311244 (OMIM: 139080) graves disease carrier ( 234) 257 67.3 3.3e-11 XP_011535591 (OMIM: 607571) PREDICTED: mitochondri ( 267) 257 67.4 3.7e-11 XP_016873060 (OMIM: 610825) PREDICTED: solute carr ( 184) 254 66.6 4.4e-11 XP_016873059 (OMIM: 610825) PREDICTED: solute carr ( 184) 254 66.6 4.4e-11 >>NP_001098117 (OMIM: 616149) solute carrier family 25 m (311 aa) initn: 1998 init1: 1998 opt: 1998 Z-score: 2449.6 bits: 461.4 E(85289): 1.1e-129 Smith-Waterman score: 1998; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311) 10 20 30 40 50 60 pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 250 260 270 280 290 300 310 pF1KB9 TYELVVYLLNG ::::::::::: NP_001 TYELVVYLLNG 310 >>NP_060625 (OMIM: 616149) solute carrier family 25 memb (310 aa) initn: 1656 init1: 1601 opt: 1980 Z-score: 2427.6 bits: 457.3 E(85289): 1.8e-128 Smith-Waterman score: 1980; 99.7% identity (99.7% similar) in 311 aa overlap (1-311:1-310) 10 20 30 40 50 60 pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TTIAYPH-VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA 250 260 270 280 290 310 pF1KB9 TYELVVYLLNG ::::::::::: NP_060 TYELVVYLLNG 300 310 >>NP_115691 (OMIM: 610816) solute carrier family 25 memb (321 aa) initn: 876 init1: 640 opt: 1240 Z-score: 1522.4 bits: 289.9 E(85289): 4.6e-78 Smith-Waterman score: 1240; 60.3% identity (84.3% similar) in 312 aa overlap (3-309:8-316) 10 20 30 40 50 pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSV---TLYISEVQLNTMA ...::.::::::::::::::.::::::.::::::: . :.: .:.:.:.. NP_115 MATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTIS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 GASVNR--VVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLN ::.. : :.:: .. :: :::::::.::::::::::::::::::.::: ::. ::..: NP_115 GAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 DVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQT .: :.:. ::..::. :.: . . ::::..:::.::. . :: ..:....:.: :::: NP_115 GIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQT 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 DGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMM .:..:::::..:::::::::.: :.::::.:. : : ::. .. : :....: :.: NP_115 EGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTE---KNSTSFFGLM 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 LAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVR ::: :: ::. :::::::.:::::::::::.:: :: :. .:::: ..:::: ..:.: NP_115 AAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIR 240 250 260 270 280 290 300 310 pF1KB9 QIPNTAIMMATYELVVYLLNG :::::::...::::.:::: NP_115 QIPNTAIVLSTYELIVYLLEDRTQ 300 310 320 >>XP_005247632 (OMIM: 616149) PREDICTED: solute carrier (204 aa) initn: 1162 init1: 1162 opt: 1162 Z-score: 1429.7 bits: 272.1 E(85289): 6.7e-73 Smith-Waterman score: 1162; 100.0% identity (100.0% similar) in 183 aa overlap (129-311:22-204) 100 110 120 130 140 150 pF1KB9 FAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRM :::::::::::::::::::::::::::::: XP_005 MGFFPASNSFVTWKSIMDRSLGFTAITATNPIWLIKTRLQLDARNRGERRM 10 20 30 40 50 160 170 180 190 200 210 pF1KB9 GAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEE 60 70 80 90 100 110 220 230 240 250 260 270 pF1KB9 SVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYG 120 130 140 150 160 170 280 290 300 310 pF1KB9 SLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG ::::::::::::::::::::::::::::::::: XP_005 SLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 180 190 200 >>XP_011540598 (OMIM: 610816) PREDICTED: solute carrier (258 aa) initn: 650 init1: 631 opt: 1016 Z-score: 1249.8 bits: 239.1 E(85289): 7.1e-63 Smith-Waterman score: 1016; 60.4% identity (84.4% similar) in 250 aa overlap (60-309:7-253) 30 40 50 60 70 80 pF1KB9 VKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLV :.:: .. :: :::::::.::::::::::: XP_011 MVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLV 10 20 30 90 100 110 120 130 140 pF1KB9 GVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLD :::::::.::: ::. ::..: .: :.:. ::..::. :.: . . ::::..:::.::. XP_011 GVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB9 ARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKT . :: ..:....:.: ::::.:..:::::..:::::::::.: :.::::.:. : : XP_011 QKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB9 ASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLS ::. .. : :....: :.: ::: :: ::. :::::::.:::::::::::.:: :: XP_011 ASSANGTE---KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTAR 160 170 180 190 200 210 270 280 290 300 310 pF1KB9 LLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG :. .:::: ..:::: ..:.::::::::...::::.:::: XP_011 LVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ 220 230 240 250 >>XP_005263560 (OMIM: 610816) PREDICTED: solute carrier (254 aa) initn: 607 init1: 607 opt: 986 Z-score: 1213.2 bits: 232.3 E(85289): 7.8e-61 Smith-Waterman score: 986; 60.6% identity (84.6% similar) in 241 aa overlap (69-309:12-249) 40 50 60 70 80 90 pF1KB9 VTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIY . :::::::.::::::::::::::::::.: XP_005 MQCFGHKETEDRSILEKEGPKSLFRGLGPNLVGVAPSRAVY 10 20 30 40 100 110 120 130 140 150 pF1KB9 FAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRM :: ::. ::..: .: :.:. ::..::. :.: . . ::::..:::.::. . :: ..: XP_005 FACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQM 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB9 GAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEE ....:.: ::::.:..:::::..:::::::::.: :.::::.:. : : ::. .. : XP_005 NTLQCARYVYQTEGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTE- 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB9 SVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYG :....: :.: ::: :: ::. :::::::.:::::::::::.:: :: :. .:::: XP_005 --KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYL 170 180 190 200 210 280 290 300 310 pF1KB9 SLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG ..:::: ..:.::::::::...::::.:::: XP_005 AFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ 220 230 240 250 >>NP_110407 (OMIM: 610815,616839) mitochondrial folate t (315 aa) initn: 434 init1: 162 opt: 416 Z-score: 514.9 bits: 103.4 E(85289): 6.1e-22 Smith-Waterman score: 433; 30.1% identity (60.5% similar) in 306 aa overlap (9-309:25-307) 10 20 30 40 pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYIS .:.:: ::... . ::..:: :. :. NP_110 MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSD------ 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 EVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSN : . : : :::: .: . .: :.:..:. ::. :.. : ..:: :. NP_110 --------GLEL-RPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNA 60 70 80 90 100 110 120 130 140 150 pF1KB9 CKE-KLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRL--QLDARNRGERRM--G : : . . . ...::: :: .. :::.:. :::: : :: . .:. : NP_110 IKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKG 110 120 130 140 150 160 160 170 180 190 200 210 pF1KB9 AFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEES :. . :.:. .:..:.:.:. . : :. ...:. :: ::. : . .. :. NP_110 MFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYE-----LLKLKYNQHINRLPEA 170 180 190 200 210 220 220 230 240 250 260 270 pF1KB9 VKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGS . ..... :: :: :.. .::..:::.::... : . ..... ..:: :. NP_110 QLSTVEYISV---AALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGG 230 240 250 260 270 280 290 300 310 pF1KB9 LYRGLTTHLVRQIPNTAIMMATYELVVYLLNG .:.:.. .:.: : : ...:: : ..: NP_110 FYKGIAPNLIRVTPACCITFVVYENVSHFLLDLREKRK 280 290 300 310 >>XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin-1 is (266 aa) initn: 295 init1: 128 opt: 346 Z-score: 430.3 bits: 87.5 E(85289): 3.2e-17 Smith-Waterman score: 346; 29.6% identity (64.0% similar) in 247 aa overlap (68-309:19-255) 40 50 60 70 80 90 pF1KB9 SVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAI :: :.. :: .::.. ..:..:..:. XP_011 MQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM 10 20 30 40 100 110 120 130 140 150 pF1KB9 YFAAYSNCKEKLNDVF--DPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGE ::: : : :. ::::: . .: .. :...:: . .. :: ..: :::. : . XP_011 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM--YNSQH 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB9 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME : .:. :.: :..:.:: .:::..... . .: :::. :: ..... ..: XP_011 R--SAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTY---- 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB9 NDEESVKEASDFVGMMLAAATSK--TCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLV . .: .. ..: . ::::. .: : . .: : : . . . .. ... . XP_011 -NPQSHIISGGLAGALAAAATTPLDVCKTLLN-TQENVALSLANISGRLSGMANAFRTVY 170 180 190 200 210 280 290 300 310 pF1KB9 QEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG : .: .. ..:. .... :.:.::: ..::. :.: XP_011 QLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 >>NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 [Ho (266 aa) initn: 295 init1: 128 opt: 346 Z-score: 430.3 bits: 87.5 E(85289): 3.2e-17 Smith-Waterman score: 346; 29.6% identity (64.0% similar) in 247 aa overlap (68-309:19-255) 40 50 60 70 80 90 pF1KB9 SVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAI :: :.. :: .::.. ..:..:..:. NP_001 MQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM 10 20 30 40 100 110 120 130 140 150 pF1KB9 YFAAYSNCKEKLNDVF--DPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGE ::: : : :. ::::: . .: .. :...:: . .. :: ..: :::. : . NP_001 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM--YNSQH 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB9 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME : .:. :.: :..:.:: .:::..... . .: :::. :: ..... ..: NP_001 R--SAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTY---- 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB9 NDEESVKEASDFVGMMLAAATSK--TCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLV . .: .. ..: . ::::. .: : . .: : : . . . .. ... . NP_001 -NPQSHIISGGLAGALAAAATTPLDVCKTLLN-TQENVALSLANISGRLSGMANAFRTVY 170 180 190 200 210 280 290 300 310 pF1KB9 QEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG : .: .. ..:. .... :.:.::: ..::. :.: NP_001 QLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 >>XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin-1 is (266 aa) initn: 295 init1: 128 opt: 346 Z-score: 430.3 bits: 87.5 E(85289): 3.2e-17 Smith-Waterman score: 346; 29.6% identity (64.0% similar) in 247 aa overlap (68-309:19-255) 40 50 60 70 80 90 pF1KB9 SVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAI :: :.. :: .::.. ..:..:..:. XP_016 MQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM 10 20 30 40 100 110 120 130 140 150 pF1KB9 YFAAYSNCKEKLNDVF--DPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGE ::: : : :. ::::: . .: .. :...:: . .. :: ..: :::. : . XP_016 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM--YNSQH 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB9 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME : .:. :.: :..:.:: .:::..... . .: :::. :: ..... ..: XP_016 R--SAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTY---- 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB9 NDEESVKEASDFVGMMLAAATSK--TCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLV . .: .. ..: . ::::. .: : . .: : : . . . .. ... . XP_016 -NPQSHIISGGLAGALAAAATTPLDVCKTLLN-TQENVALSLANISGRLSGMANAFRTVY 170 180 190 200 210 280 290 300 310 pF1KB9 QEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG : .: .. ..:. .... :.:.::: ..::. :.: XP_016 QLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 311 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:15:24 2016 done: Sat Nov 5 13:15:25 2016 Total Scan time: 6.930 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]