Result of FASTA (omim) for
pF1KB9134
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9134, 1312 aa
1>>>pF1KB9134 1312 - 1312 aa - 1312 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.8731+/-0.00074; mu= -33.4019+/- 0.045
mean_var=732.3080+/-152.454, 0's: 0 Z-trim(113.7): 433 B-trim: 0 in 0/57
Lambda= 0.047394
statistics sampled from 22829 (23231) to 22829 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.579), E-opt: 0.2 (0.272), width: 16
Scan time: 14.150
The best scores are: opt bits E(85289)
NP_005723 (OMIM: 604040,613078) DNA repair protein (1312) 8364 589.3 5.8e-167
XP_016861673 (OMIM: 602509) PREDICTED: golgin subf (2276) 450 48.4 0.00071
XP_005265128 (OMIM: 602509) PREDICTED: golgin subf (2278) 450 48.4 0.00071
NP_006297 (OMIM: 300040,300590) structural mainten (1233) 422 46.3 0.0016
XP_016880171 (OMIM: 160776) PREDICTED: myosin-10 i (1976) 425 46.6 0.0021
XP_016880170 (OMIM: 160776) PREDICTED: myosin-10 i (1976) 425 46.6 0.0021
NP_005955 (OMIM: 160776) myosin-10 isoform 2 [Homo (1976) 425 46.6 0.0021
NP_001243024 (OMIM: 160776) myosin-10 isoform 3 [H (1985) 425 46.6 0.0021
XP_016880169 (OMIM: 160776) PREDICTED: myosin-10 i (1985) 425 46.6 0.0021
XP_016880168 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 425 46.6 0.0021
XP_016880167 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 425 46.6 0.0021
XP_016880166 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 425 46.6 0.0021
XP_011522182 (OMIM: 160776) PREDICTED: myosin-10 i (2006) 425 46.6 0.0021
NP_001242941 (OMIM: 160776) myosin-10 isoform 1 [H (2007) 425 46.6 0.0021
XP_011522181 (OMIM: 160776) PREDICTED: myosin-10 i (2015) 425 46.6 0.0021
XP_011522180 (OMIM: 160776) PREDICTED: myosin-10 i (2016) 425 46.6 0.0021
XP_011522177 (OMIM: 160776) PREDICTED: myosin-10 i (2037) 425 46.6 0.0021
NP_001273663 (OMIM: 117143,616051) centromere-asso (2580) 426 46.7 0.0024
XP_011529846 (OMIM: 117143,616051) PREDICTED: cent (2676) 426 46.8 0.0025
XP_016874551 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1120) 405 45.1 0.0034
XP_016874550 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1123) 404 45.0 0.0036
XP_011527250 (OMIM: 609928) PREDICTED: myosin-7B i (1738) 403 45.1 0.0053
XP_011527249 (OMIM: 609928) PREDICTED: myosin-7B i (1738) 403 45.1 0.0053
XP_016883476 (OMIM: 609928) PREDICTED: myosin-7B i (1807) 403 45.1 0.0055
XP_016867137 (OMIM: 604001,611820) PREDICTED: A-ki (3936) 415 46.1 0.0058
NP_065935 (OMIM: 609928) myosin-7B [Homo sapiens] (1983) 403 45.1 0.0059
XP_006723903 (OMIM: 609928) PREDICTED: myosin-7B i (1989) 403 45.1 0.0059
XP_011527243 (OMIM: 609928) PREDICTED: myosin-7B i (1997) 403 45.1 0.0059
XP_016883475 (OMIM: 609928) PREDICTED: myosin-7B i (2003) 403 45.1 0.0059
XP_016874561 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1041) 389 44.0 0.0068
XP_016874547 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1138) 390 44.1 0.007
XP_016874546 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1138) 390 44.1 0.007
XP_016874541 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 389 44.0 0.0073
XP_016874544 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 389 44.0 0.0073
XP_016874542 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 389 44.0 0.0073
XP_016874545 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 389 44.0 0.0073
XP_016874543 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 389 44.0 0.0073
XP_006717488 (OMIM: 188000,610855) PREDICTED: anky (2031) 394 44.5 0.0092
XP_016871421 (OMIM: 188000,610855) PREDICTED: anky (2031) 394 44.5 0.0092
XP_011517718 (OMIM: 188000,610855) PREDICTED: anky (2062) 394 44.5 0.0093
XP_016871419 (OMIM: 188000,610855) PREDICTED: anky (2062) 394 44.5 0.0093
XP_016871420 (OMIM: 188000,610855) PREDICTED: anky (2062) 394 44.5 0.0093
XP_006717486 (OMIM: 188000,610855) PREDICTED: anky (2072) 394 44.5 0.0093
XP_016871417 (OMIM: 188000,610855) PREDICTED: anky (2112) 394 44.5 0.0095
>>NP_005723 (OMIM: 604040,613078) DNA repair protein RAD (1312 aa)
initn: 8364 init1: 8364 opt: 8364 Z-score: 3118.5 bits: 589.3 E(85289): 5.8e-167
Smith-Waterman score: 8364; 100.0% identity (100.0% similar) in 1312 aa overlap (1-1312:1-1312)
10 20 30 40 50 60
pF1KB9 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSMVCTQKSKKTEFKTLEGVITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSMVCTQKSKKTEFKTLEGVITR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDEIF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 DEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 QEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 KETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 LIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 LTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 LASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAPDKLKSTESELK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 KKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 EEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 TVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 LYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 IENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 NLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENIDNIKRNHNLALGRQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENIDNIKRNHNLALGRQKG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 YEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMKM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB9 CSAGQKVLASLIIRLALAETFCLNCGIIALDEPTTNLDRENIESLAHALVEIIKSRSQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CSAGQKVLASLIIRLALAETFCLNCGIIALDEPTTNLDRENIESLAHALVEIIKSRSQQR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KB9 NFQLLVITHDEDFVELLGRSEYVEKFYRIKKNIDQCSEIVKCSVSSLGFNVH
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NFQLLVITHDEDFVELLGRSEYVEKFYRIKKNIDQCSEIVKCSVSSLGFNVH
1270 1280 1290 1300 1310
>>XP_016861673 (OMIM: 602509) PREDICTED: golgin subfamil (2276 aa)
initn: 173 init1: 69 opt: 450 Z-score: 190.6 bits: 48.4 E(85289): 0.00071
Smith-Waterman score: 514; 21.2% identity (57.5% similar) in 1042 aa overlap (109-1118:331-1292)
80 90 100 110 120 130
pF1KB9 RAQIRLQFRDVNGELIAVQRSMVCTQKSKKTEFKTLEGVITRTKHGEKVSLSSKCAEIDR
: :::: . :.:. : .: ..: .
XP_016 KPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQE--NLLKRC----K
310 320 330 340 350
140 150 160 170 180 190
pF1KB9 EMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQ----KFDEIFSATRYIKALETLRQ
: :.: . ..:.. ::. . :.: . .:. . .... : : : ..:
XP_016 ETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL--IEQ
360 370 380 390 400 410
200 210 220 230 240 250
pF1KB9 VRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNR
..: .:. . : . ... ..::. :: :. :. :.:.. : .. ... . .
XP_016 LEQDKGMVIAETKRQMHETLEMKEE--EIA-QLRSRIKQMTTQGEELREQKEKSE--RAA
420 430 440 450 460
260 270 280 290
pF1KB9 LKEIEHNLSKIMKLDN---EIKA-LDSRKKQMEKDNSE----LEEKMEKVFQ--------
..:.:. :: .: .. ..:: .: . : .:: . : :.... .: :
XP_016 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK
470 480 490 500 510 520
300 310 320 330 340 350
pF1KB9 GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSE---LLVEQGRLQL
...::. : . :.. . .::..:. . :. .:. . :::. : . : . :
XP_016 SSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ
530 540 550 560 570 580
360 370 380 390 400 410
pF1KB9 QADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLM
.. .: . ... ..:. : . : .. .: . ::.. .. . .
XP_016 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV
590 600 610 620 630 640
420 430 440 450 460 470
pF1KB9 NDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKN-VKYELQQL----EGS
. :::. ... .. .:: : . . .. . ..: . ::. . :...: :
XP_016 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQE
650 660 670 680 690 700
480 490 500 510 520
pF1KB9 SDRILELDQELI-KAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLN
.. .:. :.:.: .:. : . . .... . :. ::..: ... .. .::..:. :.
XP_016 KETLLK-DKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLK
710 720 730 740 750 760
530 540 550 560 570 580
pF1KB9 HHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQ
.: . ..:. .: ::: :..:.... :.. . : . .. . .:::
XP_016 DQTD-KMKQEL----EAKMDEQ----KNHHQQQVDSIIKEHEVSIQRTE--KALKDQINQ
770 780 790 800 810
590 600 610 620 630 640
pF1KB9 TRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI
. : . .:.: . . .... ..::.: .:.. :: :: :.: . .:.
XP_016 LELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DV-----FQSYQSATHEQT
820 830 840 850 860
650 660 670 680 690 700
pF1KB9 EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAP
. .: : :. .: : . . ..: ..::. ..: ..:... .
XP_016 KAYEEQLA----------QLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQ
870 880 890 900 910
710 720 730 740 750 760
pF1KB9 DKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKL-QNVNRDIQRLKNDI
: ... :.. .. :.. . .:. . .: .. .:: . .. : .. : .: ...
XP_016 DLMQQLEKQNSEMEQK---VKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQK
920 930 940 950 960 970
770 780 790 800 810 820
pF1KB9 EEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGIDLDRTVQQV
.: : : . .:.: .. . :... ..:. :.:. . .: .. ....:...
XP_016 KEIEILTQKLSAKEDSIHI------LNEEYETKFKNQEKKMEK--VKQKAKEMQETLKK-
980 990 1000 1010 1020
830 840 850 860 870 880
pF1KB9 NQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLE
. :: . : . .. .::..: ..: . . :. . .... :: ..: . .
XP_016 KLLDQEAKLKKELENTALELSQK---EKQFNAKMLEMA----QANSAGISDAVSRLETNQ
1030 1040 1050 1060 1070 1080
890 900 910 920 930 940
pF1KB9 EQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIK
.. .: :::. ::..:. .: : .:..:. ::: . .. . . .... ..:
XP_016 KEQIESLTEVHR--RELNDV---ISIWE---KKLNQQAEELQEIHEIQLQEKEQEVAELK
1090 1100 1110 1120 1130
950 960 970 980 990 1000
pF1KB9 EKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMRQDI
.:. . ..... : :.. :: .: ::.. ::.. : ... .: .. .
XP_016 QKILLFGCEKEEMNKEITWLKEEGVKQ-DTTLNELQEQLKQKSAHVNSLAQDETKLKAHL
1140 1150 1160 1170 1180 1190
1010 1020 1030 1040 1050 1060
pF1KB9 DTQKIQ-ERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENIDNI
. ... .. :..: :... ::: . :: :....:. :. . .:.....
XP_016 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSEL--------TSKLKTTDEEFQSL
1200 1210 1220 1230 1240
1070 1080 1090 1100 1110 1120
pF1KB9 KRNHNLALGRQKGYEEEIIHFKKELREPQFR-DAEEKYREMMIVMRTTELVNKDLDIYYK
: .:. . .:. :.. ..::: .: .. : : : .. .:.::.:
XP_016 KSSHEKS---NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNA
1250 1260 1270 1280 1290 1300
1130 1140 1150 1160 1170 1180
pF1KB9 TLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRV
XP_016 ILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQ
1310 1320 1330 1340 1350 1360
>>XP_005265128 (OMIM: 602509) PREDICTED: golgin subfamil (2278 aa)
initn: 173 init1: 69 opt: 450 Z-score: 190.6 bits: 48.4 E(85289): 0.00071
Smith-Waterman score: 514; 21.2% identity (57.5% similar) in 1042 aa overlap (109-1118:331-1292)
80 90 100 110 120 130
pF1KB9 RAQIRLQFRDVNGELIAVQRSMVCTQKSKKTEFKTLEGVITRTKHGEKVSLSSKCAEIDR
: :::: . :.:. : .: ..: .
XP_005 KPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQE--NLLKRC----K
310 320 330 340 350
140 150 160 170 180 190
pF1KB9 EMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQ----KFDEIFSATRYIKALETLRQ
: :.: . ..:.. ::. . :.: . .:. . .... : : : ..:
XP_005 ETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL--IEQ
360 370 380 390 400 410
200 210 220 230 240 250
pF1KB9 VRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNR
..: .:. . : . ... ..::. :: :. :. :.:.. : .. ... . .
XP_005 LEQDKGMVIAETKRQMHETLEMKEE--EIA-QLRSRIKQMTTQGEELREQKEKSE--RAA
420 430 440 450 460
260 270 280 290
pF1KB9 LKEIEHNLSKIMKLDN---EIKA-LDSRKKQMEKDNSE----LEEKMEKVFQ--------
..:.:. :: .: .. ..:: .: . : .:: . : :.... .: :
XP_005 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK
470 480 490 500 510 520
300 310 320 330 340 350
pF1KB9 GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSE---LLVEQGRLQL
...::. : . :.. . .::..:. . :. .:. . :::. : . : . :
XP_005 SSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ
530 540 550 560 570 580
360 370 380 390 400 410
pF1KB9 QADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLM
.. .: . ... ..:. : . : .. .: . ::.. .. . .
XP_005 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV
590 600 610 620 630 640
420 430 440 450 460 470
pF1KB9 NDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKN-VKYELQQL----EGS
. :::. ... .. .:: : . . .. . ..: . ::. . :...: :
XP_005 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQE
650 660 670 680 690 700
480 490 500 510 520
pF1KB9 SDRILELDQELI-KAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLN
.. .:. :.:.: .:. : . . .... . :. ::..: ... .. .::..:. :.
XP_005 KETLLK-DKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLK
710 720 730 740 750 760
530 540 550 560 570 580
pF1KB9 HHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQ
.: . ..:. .: ::: :..:.... :.. . : . .. . .:::
XP_005 DQTD-KMKQEL----EAKMDEQ----KNHHQQQVDSIIKEHEVSIQRTE--KALKDQINQ
770 780 790 800 810
590 600 610 620 630 640
pF1KB9 TRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI
. : . .:.: . . .... ..::.: .:.. :: :: :.: . .:.
XP_005 LELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DV-----FQSYQSATHEQT
820 830 840 850 860
650 660 670 680 690 700
pF1KB9 EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQSKLRLAP
. .: : :. .: : . . ..: ..::. ..: ..:... .
XP_005 KAYEEQLA----------QLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQ
870 880 890 900 910
710 720 730 740 750 760
pF1KB9 DKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKL-QNVNRDIQRLKNDI
: ... :.. .. :.. . .:. . .: .. .:: . .. : .. : .: ...
XP_005 DLMQQLEKQNSEMEQK---VKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQK
920 930 940 950 960 970
770 780 790 800 810 820
pF1KB9 EEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGIDLDRTVQQV
.: : : . .:.: .. . :... ..:. :.:. . .: .. ....:...
XP_005 KEIEILTQKLSAKEDSIHI------LNEEYETKFKNQEKKMEK--VKQKAKEMQETLKK-
980 990 1000 1010 1020
830 840 850 860 870 880
pF1KB9 NQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLE
. :: . : . .. .::..: ..: . . :. . .... :: ..: . .
XP_005 KLLDQEAKLKKELENTALELSQK---EKQFNAKMLEMA----QANSAGISDAVSRLETNQ
1030 1040 1050 1060 1070 1080
890 900 910 920 930 940
pF1KB9 EQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIK
.. .: :::. ::..:. .: : .:..:. ::: . .. . . .... ..:
XP_005 KEQIESLTEVHR--RELNDV---ISIWE---KKLNQQAEELQEIHEIQLQEKEQEVAELK
1090 1100 1110 1120 1130
950 960 970 980 990 1000
pF1KB9 EKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMRQDI
.:. . ..... : :.. :: .: ::.. ::.. : ... .: .. .
XP_005 QKILLFGCEKEEMNKEITWLKEEGVKQ-DTTLNELQEQLKQKSAHVNSLAQDETKLKAHL
1140 1150 1160 1170 1180 1190
1010 1020 1030 1040 1050 1060
pF1KB9 DTQKIQ-ERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENIDNI
. ... .. :..: :... ::: . :: :....:. :. . .:.....
XP_005 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSEL--------TSKLKTTDEEFQSL
1200 1210 1220 1230 1240
1070 1080 1090 1100 1110 1120
pF1KB9 KRNHNLALGRQKGYEEEIIHFKKELREPQFR-DAEEKYREMMIVMRTTELVNKDLDIYYK
: .:. . .:. :.. ..::: .: .. : : : .. .:.::.:
XP_005 KSSHEKS---NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNA
1250 1260 1270 1280 1290 1300
1130 1140 1150 1160 1170 1180
pF1KB9 TLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNYNYRV
XP_005 ILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQ
1310 1320 1330 1340 1350 1360
>>NP_006297 (OMIM: 300040,300590) structural maintenance (1233 aa)
initn: 302 init1: 92 opt: 422 Z-score: 184.0 bits: 46.3 E(85289): 0.0016
Smith-Waterman score: 492; 21.1% identity (54.6% similar) in 1301 aa overlap (20-1273:16-1193)
10 20 30 40 50 60
pF1KB9 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG
: .::: :. .: ..::::.::..... .... :. .
NP_006 MGFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDAISFV-LGEKTSN
10 20 30 40 50
70 80 90 100 110
pF1KB9 TKGNTF---VHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSMVCTQKSKKTEFKTLEGV
. .:. .: :.. . :: . . . . ..: . : .: . ..:.: . :
NP_006 LRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIV----GGSSEYKINNKV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 ITRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNW--PLSEGKALKQK
. ...:.. . . .. . .: . ...: .: . .:.. : :.
NP_006 VQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKN----PKERTALFEEISRSGELAQE
120 130 140 150 160
180 190 200 210 220 230
pF1KB9 FDEIFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKA---CEIRDQITSKEA
.:. ...:: : : . .. :. : : :: ::.: ...:... ..
NP_006 YDK--RKKEMVKAEEDT----QFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQV
170 180 190 200 210 220
240 250 260 270 280
pF1KB9 QLTSSKEIVKSYENELD------PLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDN
:: .. : :.::.. : .. ::::.. ... :...:.: .::.. :
NP_006 QL----QLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKE---KKKELGKMM
230 240 250 260 270
290 300 310 320 330 340
pF1KB9 SELEEKMEKVFQGTDEQLND---LYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEK
: ....:: .. : .::. : . .... .: .:: .. :.. .:. . . .
NP_006 RE-QQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDM
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB9 SELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRER
.:: :. :... :.. . : .. :: . .: :. : :.:..:.: .:.
NP_006 DEL--EKEMLSVEKARQEFEERMEEES-QSQGRDLTLE--------ENQVKKYHRL-KEE
340 350 360 370 380
410 420 430 440 450 460
pF1KB9 QEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYE
.: : : .. : . . : ..: ....: : ..: : .: .
NP_006 ASKRAATLAQELEKFNRDQKADQDRLD-LEERK---------------KVETEAK-IKQK
390 400 410 420
470 480 490 500 510 520
pF1KB9 LQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQ
:...: .. :: .:.. . ... : . .: . : ..:. : .:. ..:.:
NP_006 LREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMA-----KRRIDEINKELNQ
430 440 450 460 470
530 540 550 560 570 580
pF1KB9 EMEQLNHHTTTRTQMEMLTKDKADKDEQIRKI-KSRHSDELTSLLGYFPNKKQLEDWLHS
::::. : : . ::. :.:... . .: .: .: :. .
NP_006 VMEQLGDARIDR-QESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQI-----A
480 490 500 510 520 530
590 600 610 620 630
pF1KB9 KSKEINQTRDRLA----KLNKE-LASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQD
.: .... : . : ... . ...... .. : ... ..:: .. :..
NP_006 VTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELKGAK-
540 550 560 570 580 590
640 650 660 670 680 690
pF1KB9 FESDLDRLKEEIEKSSKQRA---MLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAEL
. :. : . :.. : : :. .. .. :. . .. . .:: . .
NP_006 LVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVALDGTLFQKSGVI
600 610 620 630 640 650
700 710 720 730 740 750
pF1KB9 QEVISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKL
. :::..: : .: . ..::.:..: : : .: :: :. .....
NP_006 SGGASDLKAKARRWDEK---AVDKLKEKKERLTEELK----EQMKAKRKEAELRQVQSQA
660 670 680 690 700
760 770 780 790 800 810
pF1KB9 QNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAA
.... .. ..:.:. .: . .:..:. . . : ...:..: : ..
NP_006 HGLQMRLKYSQSDLEQTKTR-HLALNLQEKSKLE----SELANFGPRINDIKRIIQSRER
710 720 730 740 750 760
820 830 840 850 860
pF1KB9 KLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQE------QIQHLKSTTN
... :: . ..::..: :. . : . :.... .. :.: .... :. .
NP_006 EMK--DLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG
770 780 790 800 810
870 880 890 900 910 920
pF1KB9 -ELKSEKLQISTNLQRRQQLEEQTVELS-TEVQSLYREIKDAKEQVSPLETTLEKFQQEK
.: :: :.. . : . .. ::::. . .:...: .: ..... .. :. ..:. :
NP_006 IQLDFEKNQLKED-QDKVHMWEQTVKKDENEIEKLKKE---EQRHMKIIDETMAQLQDLK
820 830 840 850 860 870
930 940 950 960 970 980
pF1KB9 EELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQ
.. . ::. : :: ....: :.. : :.. ...: . . : . .
NP_006 NQHLAKKSEVN----DKNHEMEEIRKKLGGANKEM-THLQKEVTAIETKLEQKRSDRHNL
880 890 900 910 920
990 1000 1010 1020 1030
pF1KB9 LSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKR------NEELKEVEE-ERK
:. :. . :. . : .:: .:. .:... .: : : :.. .
NP_006 LQACKMQDIKLPLSKGTM-DDI-SQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLC
930 940 950 960 970 980
1040 1050 1060 1070 1080 1090
pF1KB9 QHLKE-MGQMQVLQ-MKSEHQKLEENIDNIKRNHNLALGRQKGYEE-EIIHFKKELREPQ
. ::. ... .. : :.. .:::.:. . ..: .: .:..:. : .. : . .
NP_006 EDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQR---IAAPNMKAMEKLESVRDKFQETSDE
990 1000 1010 1020 1030 1040
1100 1110 1120 1130 1140 1150
pF1KB9 FRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSM--KMEEINKII-RDLWRS
:. :... .. . .. : ..:. .:. :.:. ...:: : . :. .
NP_006 FEAARKRAKK---AKQAFEQIKKE------RFDRFNACFESVATNIDEIYKALSRNSSAQ
1050 1060 1070 1080 1090
1160 1170 1180 1190 1200 1210
pF1KB9 TYRGQDIEYIEIRSDADENVSASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLII
.. : . . . : : :: .: .: :.:.:..:.: .
NP_006 AFLGPENPEEPYLDGINYNCVAPGKR----FR--------PMD---NLSGGEKTVAALAL
1100 1110 1120 1130 1140
1220 1230 1240 1250 1260 1270
pF1KB9 RLALAETFCLNCGIIALDEPTTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDF
.:. ... ...::: . :: :: ..:. :: .: ::: .::. :.:
NP_006 LFAI-HSYK-PAPFFVLDEIDAALDNTNIGKVAN----YIKEQSTC-NFQAIVISLKEEF
1150 1160 1170 1180 1190
1280 1290 1300 1310
pF1KB9 VELLGRSEYVEKFYRIKKNIDQCSEIVKCSVSSLGFNVH
NP_006 YTKAESLIGVYPEQGDCVISKVLTFDLTKYPDANPNPNEQ
1200 1210 1220 1230
>>XP_016880171 (OMIM: 160776) PREDICTED: myosin-10 isofo (1976 aa)
initn: 140 init1: 85 opt: 425 Z-score: 182.2 bits: 46.6 E(85289): 0.0021
Smith-Waterman score: 514; 21.6% identity (58.7% similar) in 958 aa overlap (183-1096:839-1749)
160 170 180 190 200
pF1KB9 NVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQ-----KVKEYQ
:. :.. :: .. :.. :::: :
XP_016 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ
810 820 830 840 850 860
210 220 230 240 250 260
pF1KB9 MELK-YLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYEN---ELDPLKNRLKEIEHNL-
... :.....: .. .. . :: . :. :. .: :..:.:: :.:
XP_016 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLE
870 880 890 900 910 920
270 280 290 300 310 320
pF1KB9 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL
:.. . ... . :...::.:. ..:::.... .:. ..:. . . ... :...
XP_016 SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKLQLEKVTAEAKIKKMEEEI
930 940 950 960 970 980
330 340 350 360 370 380
pF1KB9 VDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDG
. . . :. ::..:.... .: ...: . .. .. . :.. . . ..::
XP_016 LLLEDQNSKFIKEKKLMEDRIAEC---SSQLAEEEEKAKNLAKIRNKQ-EVMISDLE---
990 1000 1010 1020 1030 1040
390 400 410 420 430
pF1KB9 FERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIR----DKKTG
:: :. ....: .... .:: ...:....:: : ::::.. :.
XP_016 -ERLKKEEKTRQELEK-AKRKLDGE---TTDLQDQIAE----LQAQIDELKLQLAKKEEE
1050 1060 1070 1080 1090
440 450 460 470 480 490
pF1KB9 L-GRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNV
: : . . .: : .:.: :: :. ::: .: ::.... . . .::::..
XP_016 LQGALARGDDETL-HKNNALKVVR-ELQA------QIAELQEDFESEKASRNKAEKQK--
1100 1110 1120 1130 1140
500 510 520 530 540 550
pF1KB9 ETLKMEVISLQNEKAD-LDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIK
. :. :. .:..: : :: : . ::.. .. ... . . : .. ... ::. ..
XP_016 RDLSEELEALKTELEDTLDTTAAQ--QELRTKREQEVAELK-KALEEETKNHEAQIQDMR
1150 1160 1170 1180 1190
560 570 580 590 600 610
pF1KB9 SRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELK
.::. : : ..:::. . :.. ...... : ::::: . .... : .
XP_016 QRHATALEEL------SEQLEQAKRFKAN-LEKNKQGLETDNKELACEVKVLQQVKAESE
1200 1210 1220 1230 1240 1250
620 630 640 650 660 670
pF1KB9 RKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI-EKSSKQRAMLAGATAVYSQFITQLTD
.:...:.. ..: :. :::. :. ::.:: . : ..... . .
XP_016 HKRKKLDAQVQELHAKV------SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK
1260 1270 1280 1290 1300
680 690 700 710 720 730
pF1KB9 ENQSCCPVCQRVFQTEAELQEVIS---DLQSKLR-LAPDKLKSTESELKKKEKRRDEMLG
.. . ... .:. ::: .:.:..: : .: . :.. ...: :..
XP_016 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ
1310 1320 1330 1340 1350 1360
740 750 760 770 780
pF1KB9 LVPMRQSIIDLKEK------EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESA
.. ..... : :.: : :.. ... .: . :.. .::. . ..
XP_016 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL
1370 1380 1390 1400 1410 1420
790 800 810 820 830
pF1KB9 KVCLTDVTIMERFQME----LKDVERKIAQQAAKLQGIDLDRTVQQ--VNQEKQEKQHKL
. : :.:. : . :. ..:. : :. ..:. . .. .. : .::. :
XP_016 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA
1430 1440 1450 1460 1470 1480
840 850 860 870 880 890
pF1KB9 DTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQR----RQQLEEQTVELS
... .: . .. ..: ..:.. ..: : : ... :... .. ::.:. :.
XP_016 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR
1490 1500 1510 1520 1530 1540
900 910 920 930 940 950
pF1KB9 TEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIH
:... : :.. ... ::.... .. . :. .. .. .: ..: . ..:....
XP_016 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN---EEKKRLLIKQVRELE
1550 1560 1570 1580 1590 1600
960 970 980 990 1000 1010
pF1KB9 GYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMR-LMRQDIDTQKIQ
. ..: : . ::. : .:. . ::. .: .... ...: :. : : :.
XP_016 AELED-ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL
1610 1620 1630 1640 1650 1660
1020 1030 1040 1050 1060
pF1KB9 E--RWLQDNLTLRKRNEE--LKEVEEERKQHLKEMGQMQVLQMKSEHQK--LEENIDNIK
: : .:.. .... : :: .: : : .:... . . ..:... : ..: :
XP_016 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA
1670 1680 1690 1700 1710 1720
1070 1080 1090 1100 1110 1120
pF1KB9 RNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTL
... : ... : .: ....::.: :
XP_016 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ
1730 1740 1750 1760 1770 1780
>>XP_016880170 (OMIM: 160776) PREDICTED: myosin-10 isofo (1976 aa)
initn: 140 init1: 85 opt: 425 Z-score: 182.2 bits: 46.6 E(85289): 0.0021
Smith-Waterman score: 514; 21.6% identity (58.7% similar) in 958 aa overlap (183-1096:839-1749)
160 170 180 190 200
pF1KB9 NVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQ-----KVKEYQ
:. :.. :: .. :.. :::: :
XP_016 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ
810 820 830 840 850 860
210 220 230 240 250 260
pF1KB9 MELK-YLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYEN---ELDPLKNRLKEIEHNL-
... :.....: .. .. . :: . :. :. .: :..:.:: :.:
XP_016 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLE
870 880 890 900 910 920
270 280 290 300 310 320
pF1KB9 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL
:.. . ... . :...::.:. ..:::.... .:. ..:. . . ... :...
XP_016 SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKLQLEKVTAEAKIKKMEEEI
930 940 950 960 970 980
330 340 350 360 370 380
pF1KB9 VDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDG
. . . :. ::..:.... .: ...: . .. .. . :.. . . ..::
XP_016 LLLEDQNSKFIKEKKLMEDRIAEC---SSQLAEEEEKAKNLAKIRNKQ-EVMISDLE---
990 1000 1010 1020 1030 1040
390 400 410 420 430
pF1KB9 FERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIR----DKKTG
:: :. ....: .... .:: ...:....:: : ::::.. :.
XP_016 -ERLKKEEKTRQELEK-AKRKLDGE---TTDLQDQIAE----LQAQIDELKLQLAKKEEE
1050 1060 1070 1080 1090
440 450 460 470 480 490
pF1KB9 L-GRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNV
: : . . .: : .:.: :: :. ::: .: ::.... . . .::::..
XP_016 LQGALARGDDETL-HKNNALKVVR-ELQA------QIAELQEDFESEKASRNKAEKQK--
1100 1110 1120 1130 1140
500 510 520 530 540 550
pF1KB9 ETLKMEVISLQNEKAD-LDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIK
. :. :. .:..: : :: : . ::.. .. ... . . : .. ... ::. ..
XP_016 RDLSEELEALKTELEDTLDTTAAQ--QELRTKREQEVAELK-KALEEETKNHEAQIQDMR
1150 1160 1170 1180 1190
560 570 580 590 600 610
pF1KB9 SRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELK
.::. : : ..:::. . :.. ...... : ::::: . .... : .
XP_016 QRHATALEEL------SEQLEQAKRFKAN-LEKNKQGLETDNKELACEVKVLQQVKAESE
1200 1210 1220 1230 1240 1250
620 630 640 650 660 670
pF1KB9 RKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI-EKSSKQRAMLAGATAVYSQFITQLTD
.:...:.. ..: :. :::. :. ::.:: . : ..... . .
XP_016 HKRKKLDAQVQELHAKV------SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK
1260 1270 1280 1290 1300
680 690 700 710 720 730
pF1KB9 ENQSCCPVCQRVFQTEAELQEVIS---DLQSKLR-LAPDKLKSTESELKKKEKRRDEMLG
.. . ... .:. ::: .:.:..: : .: . :.. ...: :..
XP_016 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ
1310 1320 1330 1340 1350 1360
740 750 760 770 780
pF1KB9 LVPMRQSIIDLKEK------EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESA
.. ..... : :.: : :.. ... .: . :.. .::. . ..
XP_016 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL
1370 1380 1390 1400 1410 1420
790 800 810 820 830
pF1KB9 KVCLTDVTIMERFQME----LKDVERKIAQQAAKLQGIDLDRTVQQ--VNQEKQEKQHKL
. : :.:. : . :. ..:. : :. ..:. . .. .. : .::. :
XP_016 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA
1430 1440 1450 1460 1470 1480
840 850 860 870 880 890
pF1KB9 DTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQR----RQQLEEQTVELS
... .: . .. ..: ..:.. ..: : : ... :... .. ::.:. :.
XP_016 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR
1490 1500 1510 1520 1530 1540
900 910 920 930 940 950
pF1KB9 TEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIH
:... : :.. ... ::.... .. . :. .. .. .: ..: . ..:....
XP_016 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN---EEKKRLLIKQVRELE
1550 1560 1570 1580 1590 1600
960 970 980 990 1000 1010
pF1KB9 GYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMR-LMRQDIDTQKIQ
. ..: : . ::. : .:. . ::. .: .... ...: :. : : :.
XP_016 AELED-ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL
1610 1620 1630 1640 1650 1660
1020 1030 1040 1050 1060
pF1KB9 E--RWLQDNLTLRKRNEE--LKEVEEERKQHLKEMGQMQVLQMKSEHQK--LEENIDNIK
: : .:.. .... : :: .: : : .:... . . ..:... : ..: :
XP_016 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA
1670 1680 1690 1700 1710 1720
1070 1080 1090 1100 1110 1120
pF1KB9 RNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTL
... : ... : .: ....::.: :
XP_016 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ
1730 1740 1750 1760 1770 1780
>>NP_005955 (OMIM: 160776) myosin-10 isoform 2 [Homo sap (1976 aa)
initn: 140 init1: 85 opt: 425 Z-score: 182.2 bits: 46.6 E(85289): 0.0021
Smith-Waterman score: 514; 21.6% identity (58.7% similar) in 958 aa overlap (183-1096:839-1749)
160 170 180 190 200
pF1KB9 NVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQ-----KVKEYQ
:. :.. :: .. :.. :::: :
NP_005 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ
810 820 830 840 850 860
210 220 230 240 250 260
pF1KB9 MELK-YLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYEN---ELDPLKNRLKEIEHNL-
... :.....: .. .. . :: . :. :. .: :..:.:: :.:
NP_005 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLE
870 880 890 900 910 920
270 280 290 300 310 320
pF1KB9 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL
:.. . ... . :...::.:. ..:::.... .:. ..:. . . ... :...
NP_005 SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKLQLEKVTAEAKIKKMEEEI
930 940 950 960 970 980
330 340 350 360 370 380
pF1KB9 VDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDG
. . . :. ::..:.... .: ...: . .. .. . :.. . . ..::
NP_005 LLLEDQNSKFIKEKKLMEDRIAEC---SSQLAEEEEKAKNLAKIRNKQ-EVMISDLE---
990 1000 1010 1020 1030 1040
390 400 410 420 430
pF1KB9 FERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIR----DKKTG
:: :. ....: .... .:: ...:....:: : ::::.. :.
NP_005 -ERLKKEEKTRQELEK-AKRKLDGE---TTDLQDQIAE----LQAQIDELKLQLAKKEEE
1050 1060 1070 1080 1090
440 450 460 470 480 490
pF1KB9 L-GRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNV
: : . . .: : .:.: :: :. ::: .: ::.... . . .::::..
NP_005 LQGALARGDDETL-HKNNALKVVR-ELQA------QIAELQEDFESEKASRNKAEKQK--
1100 1110 1120 1130 1140
500 510 520 530 540 550
pF1KB9 ETLKMEVISLQNEKAD-LDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIK
. :. :. .:..: : :: : . ::.. .. ... . . : .. ... ::. ..
NP_005 RDLSEELEALKTELEDTLDTTAAQ--QELRTKREQEVAELK-KALEEETKNHEAQIQDMR
1150 1160 1170 1180 1190
560 570 580 590 600 610
pF1KB9 SRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELK
.::. : : ..:::. . :.. ...... : ::::: . .... : .
NP_005 QRHATALEEL------SEQLEQAKRFKAN-LEKNKQGLETDNKELACEVKVLQQVKAESE
1200 1210 1220 1230 1240 1250
620 630 640 650 660 670
pF1KB9 RKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI-EKSSKQRAMLAGATAVYSQFITQLTD
.:...:.. ..: :. :::. :. ::.:: . : ..... . .
NP_005 HKRKKLDAQVQELHAKV------SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK
1260 1270 1280 1290 1300
680 690 700 710 720 730
pF1KB9 ENQSCCPVCQRVFQTEAELQEVIS---DLQSKLR-LAPDKLKSTESELKKKEKRRDEMLG
.. . ... .:. ::: .:.:..: : .: . :.. ...: :..
NP_005 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ
1310 1320 1330 1340 1350 1360
740 750 760 770 780
pF1KB9 LVPMRQSIIDLKEK------EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESA
.. ..... : :.: : :.. ... .: . :.. .::. . ..
NP_005 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL
1370 1380 1390 1400 1410 1420
790 800 810 820 830
pF1KB9 KVCLTDVTIMERFQME----LKDVERKIAQQAAKLQGIDLDRTVQQ--VNQEKQEKQHKL
. : :.:. : . :. ..:. : :. ..:. . .. .. : .::. :
NP_005 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA
1430 1440 1450 1460 1470 1480
840 850 860 870 880 890
pF1KB9 DTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQR----RQQLEEQTVELS
... .: . .. ..: ..:.. ..: : : ... :... .. ::.:. :.
NP_005 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR
1490 1500 1510 1520 1530 1540
900 910 920 930 940 950
pF1KB9 TEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIH
:... : :.. ... ::.... .. . :. .. .. .: ..: . ..:....
NP_005 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN---EEKKRLLIKQVRELE
1550 1560 1570 1580 1590 1600
960 970 980 990 1000 1010
pF1KB9 GYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMR-LMRQDIDTQKIQ
. ..: : . ::. : .:. . ::. .: .... ...: :. : : :.
NP_005 AELED-ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL
1610 1620 1630 1640 1650 1660
1020 1030 1040 1050 1060
pF1KB9 E--RWLQDNLTLRKRNEE--LKEVEEERKQHLKEMGQMQVLQMKSEHQK--LEENIDNIK
: : .:.. .... : :: .: : : .:... . . ..:... : ..: :
NP_005 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA
1670 1680 1690 1700 1710 1720
1070 1080 1090 1100 1110 1120
pF1KB9 RNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTL
... : ... : .: ....::.: :
NP_005 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ
1730 1740 1750 1760 1770 1780
>>NP_001243024 (OMIM: 160776) myosin-10 isoform 3 [Homo (1985 aa)
initn: 140 init1: 85 opt: 425 Z-score: 182.2 bits: 46.6 E(85289): 0.0021
Smith-Waterman score: 514; 21.6% identity (58.7% similar) in 958 aa overlap (183-1096:848-1758)
160 170 180 190 200
pF1KB9 NVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQ-----KVKEYQ
:. :.. :: .. :.. :::: :
NP_001 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ
820 830 840 850 860 870
210 220 230 240 250 260
pF1KB9 MELK-YLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYEN---ELDPLKNRLKEIEHNL-
... :.....: .. .. . :: . :. :. .: :..:.:: :.:
NP_001 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLE
880 890 900 910 920 930
270 280 290 300 310 320
pF1KB9 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL
:.. . ... . :...::.:. ..:::.... .:. ..:. . . ... :...
NP_001 SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKLQLEKVTAEAKIKKMEEEI
940 950 960 970 980 990
330 340 350 360 370 380
pF1KB9 VDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDG
. . . :. ::..:.... .: ...: . .. .. . :.. . . ..::
NP_001 LLLEDQNSKFIKEKKLMEDRIAEC---SSQLAEEEEKAKNLAKIRNKQ-EVMISDLE---
1000 1010 1020 1030 1040
390 400 410 420 430
pF1KB9 FERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIR----DKKTG
:: :. ....: .... .:: ...:....:: : ::::.. :.
NP_001 -ERLKKEEKTRQELEK-AKRKLDGE---TTDLQDQIAE----LQAQIDELKLQLAKKEEE
1050 1060 1070 1080 1090 1100
440 450 460 470 480 490
pF1KB9 L-GRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNV
: : . . .: : .:.: :: :. ::: .: ::.... . . .::::..
NP_001 LQGALARGDDETL-HKNNALKVVR-ELQA------QIAELQEDFESEKASRNKAEKQK--
1110 1120 1130 1140 1150
500 510 520 530 540 550
pF1KB9 ETLKMEVISLQNEKAD-LDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIK
. :. :. .:..: : :: : . ::.. .. ... . . : .. ... ::. ..
NP_001 RDLSEELEALKTELEDTLDTTAAQ--QELRTKREQEVAELK-KALEEETKNHEAQIQDMR
1160 1170 1180 1190 1200
560 570 580 590 600 610
pF1KB9 SRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELK
.::. : : ..:::. . :.. ...... : ::::: . .... : .
NP_001 QRHATALEEL------SEQLEQAKRFKAN-LEKNKQGLETDNKELACEVKVLQQVKAESE
1210 1220 1230 1240 1250 1260
620 630 640 650 660 670
pF1KB9 RKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI-EKSSKQRAMLAGATAVYSQFITQLTD
.:...:.. ..: :. :::. :. ::.:: . : ..... . .
NP_001 HKRKKLDAQVQELHAKV------SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK
1270 1280 1290 1300 1310
680 690 700 710 720 730
pF1KB9 ENQSCCPVCQRVFQTEAELQEVIS---DLQSKLR-LAPDKLKSTESELKKKEKRRDEMLG
.. . ... .:. ::: .:.:..: : .: . :.. ...: :..
NP_001 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ
1320 1330 1340 1350 1360 1370
740 750 760 770 780
pF1KB9 LVPMRQSIIDLKEK------EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESA
.. ..... : :.: : :.. ... .: . :.. .::. . ..
NP_001 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL
1380 1390 1400 1410 1420 1430
790 800 810 820 830
pF1KB9 KVCLTDVTIMERFQME----LKDVERKIAQQAAKLQGIDLDRTVQQ--VNQEKQEKQHKL
. : :.:. : . :. ..:. : :. ..:. . .. .. : .::. :
NP_001 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA
1440 1450 1460 1470 1480 1490
840 850 860 870 880 890
pF1KB9 DTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQR----RQQLEEQTVELS
... .: . .. ..: ..:.. ..: : : ... :... .. ::.:. :.
NP_001 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR
1500 1510 1520 1530 1540 1550
900 910 920 930 940 950
pF1KB9 TEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIH
:... : :.. ... ::.... .. . :. .. .. .: ..: . ..:....
NP_001 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN---EEKKRLLIKQVRELE
1560 1570 1580 1590 1600 1610
960 970 980 990 1000 1010
pF1KB9 GYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMR-LMRQDIDTQKIQ
. ..: : . ::. : .:. . ::. .: .... ...: :. : : :.
NP_001 AELED-ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL
1620 1630 1640 1650 1660 1670
1020 1030 1040 1050 1060
pF1KB9 E--RWLQDNLTLRKRNEE--LKEVEEERKQHLKEMGQMQVLQMKSEHQK--LEENIDNIK
: : .:.. .... : :: .: : : .:... . . ..:... : ..: :
NP_001 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA
1680 1690 1700 1710 1720 1730
1070 1080 1090 1100 1110 1120
pF1KB9 RNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTL
... : ... : .: ....::.: :
NP_001 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ
1740 1750 1760 1770 1780 1790
>>XP_016880169 (OMIM: 160776) PREDICTED: myosin-10 isofo (1985 aa)
initn: 140 init1: 85 opt: 425 Z-score: 182.2 bits: 46.6 E(85289): 0.0021
Smith-Waterman score: 514; 21.6% identity (58.7% similar) in 958 aa overlap (183-1096:848-1758)
160 170 180 190 200
pF1KB9 NVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQ-----KVKEYQ
:. :.. :: .. :.. :::: :
XP_016 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ
820 830 840 850 860 870
210 220 230 240 250 260
pF1KB9 MELK-YLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYEN---ELDPLKNRLKEIEHNL-
... :.....: .. .. . :: . :. :. .: :..:.:: :.:
XP_016 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLE
880 890 900 910 920 930
270 280 290 300 310 320
pF1KB9 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL
:.. . ... . :...::.:. ..:::.... .:. ..:. . . ... :...
XP_016 SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKLQLEKVTAEAKIKKMEEEI
940 950 960 970 980 990
330 340 350 360 370 380
pF1KB9 VDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDG
. . . :. ::..:.... .: ...: . .. .. . :.. . . ..::
XP_016 LLLEDQNSKFIKEKKLMEDRIAEC---SSQLAEEEEKAKNLAKIRNKQ-EVMISDLE---
1000 1010 1020 1030 1040
390 400 410 420 430
pF1KB9 FERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIR----DKKTG
:: :. ....: .... .:: ...:....:: : ::::.. :.
XP_016 -ERLKKEEKTRQELEK-AKRKLDGE---TTDLQDQIAE----LQAQIDELKLQLAKKEEE
1050 1060 1070 1080 1090 1100
440 450 460 470 480 490
pF1KB9 L-GRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNV
: : . . .: : .:.: :: :. ::: .: ::.... . . .::::..
XP_016 LQGALARGDDETL-HKNNALKVVR-ELQA------QIAELQEDFESEKASRNKAEKQK--
1110 1120 1130 1140 1150
500 510 520 530 540 550
pF1KB9 ETLKMEVISLQNEKAD-LDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIK
. :. :. .:..: : :: : . ::.. .. ... . . : .. ... ::. ..
XP_016 RDLSEELEALKTELEDTLDTTAAQ--QELRTKREQEVAELK-KALEEETKNHEAQIQDMR
1160 1170 1180 1190 1200
560 570 580 590 600 610
pF1KB9 SRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELK
.::. : : ..:::. . :.. ...... : ::::: . .... : .
XP_016 QRHATALEEL------SEQLEQAKRFKAN-LEKNKQGLETDNKELACEVKVLQQVKAESE
1210 1220 1230 1240 1250 1260
620 630 640 650 660 670
pF1KB9 RKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI-EKSSKQRAMLAGATAVYSQFITQLTD
.:...:.. ..: :. :::. :. ::.:: . : ..... . .
XP_016 HKRKKLDAQVQELHAKV------SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK
1270 1280 1290 1300 1310
680 690 700 710 720 730
pF1KB9 ENQSCCPVCQRVFQTEAELQEVIS---DLQSKLR-LAPDKLKSTESELKKKEKRRDEMLG
.. . ... .:. ::: .:.:..: : .: . :.. ...: :..
XP_016 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ
1320 1330 1340 1350 1360 1370
740 750 760 770 780
pF1KB9 LVPMRQSIIDLKEK------EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESA
.. ..... : :.: : :.. ... .: . :.. .::. . ..
XP_016 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL
1380 1390 1400 1410 1420 1430
790 800 810 820 830
pF1KB9 KVCLTDVTIMERFQME----LKDVERKIAQQAAKLQGIDLDRTVQQ--VNQEKQEKQHKL
. : :.:. : . :. ..:. : :. ..:. . .. .. : .::. :
XP_016 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA
1440 1450 1460 1470 1480 1490
840 850 860 870 880 890
pF1KB9 DTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQR----RQQLEEQTVELS
... .: . .. ..: ..:.. ..: : : ... :... .. ::.:. :.
XP_016 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR
1500 1510 1520 1530 1540 1550
900 910 920 930 940 950
pF1KB9 TEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIH
:... : :.. ... ::.... .. . :. .. .. .: ..: . ..:....
XP_016 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN---EEKKRLLIKQVRELE
1560 1570 1580 1590 1600 1610
960 970 980 990 1000 1010
pF1KB9 GYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMR-LMRQDIDTQKIQ
. ..: : . ::. : .:. . ::. .: .... ...: :. : : :.
XP_016 AELED-ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL
1620 1630 1640 1650 1660 1670
1020 1030 1040 1050 1060
pF1KB9 E--RWLQDNLTLRKRNEE--LKEVEEERKQHLKEMGQMQVLQMKSEHQK--LEENIDNIK
: : .:.. .... : :: .: : : .:... . . ..:... : ..: :
XP_016 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA
1680 1690 1700 1710 1720 1730
1070 1080 1090 1100 1110 1120
pF1KB9 RNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTL
... : ... : .: ....::.: :
XP_016 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ
1740 1750 1760 1770 1780 1790
>>XP_016880168 (OMIM: 160776) PREDICTED: myosin-10 isofo (1986 aa)
initn: 140 init1: 85 opt: 425 Z-score: 182.2 bits: 46.6 E(85289): 0.0021
Smith-Waterman score: 514; 21.6% identity (58.7% similar) in 958 aa overlap (183-1096:849-1759)
160 170 180 190 200
pF1KB9 NVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQ-----KVKEYQ
:. :.. :: .. :.. :::: :
XP_016 KQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ
820 830 840 850 860 870
210 220 230 240 250 260
pF1KB9 MELK-YLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYEN---ELDPLKNRLKEIEHNL-
... :.....: .. .. . :: . :. :. .: :..:.:: :.:
XP_016 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLE
880 890 900 910 920 930
270 280 290 300 310 320
pF1KB9 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL
:.. . ... . :...::.:. ..:::.... .:. ..:. . . ... :...
XP_016 SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EGARQKLQLEKVTAEAKIKKMEEEI
940 950 960 970 980 990
330 340 350 360 370 380
pF1KB9 VDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDG
. . . :. ::..:.... .: ...: . .. .. . :.. . . ..::
XP_016 LLLEDQNSKFIKEKKLMEDRIAEC---SSQLAEEEEKAKNLAKIRNKQ-EVMISDLE---
1000 1010 1020 1030 1040 1050
390 400 410 420 430
pF1KB9 FERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIR----DKKTG
:: :. ....: .... .:: ...:....:: : ::::.. :.
XP_016 -ERLKKEEKTRQELEK-AKRKLDGE---TTDLQDQIAE----LQAQIDELKLQLAKKEEE
1060 1070 1080 1090 1100
440 450 460 470 480 490
pF1KB9 L-GRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNV
: : . . .: : .:.: :: :. ::: .: ::.... . . .::::..
XP_016 LQGALARGDDETL-HKNNALKVVR-ELQA------QIAELQEDFESEKASRNKAEKQK--
1110 1120 1130 1140 1150
500 510 520 530 540 550
pF1KB9 ETLKMEVISLQNEKAD-LDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIK
. :. :. .:..: : :: : . ::.. .. ... . . : .. ... ::. ..
XP_016 RDLSEELEALKTELEDTLDTTAAQ--QELRTKREQEVAELK-KALEEETKNHEAQIQDMR
1160 1170 1180 1190 1200
560 570 580 590 600 610
pF1KB9 SRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELK
.::. : : ..:::. . :.. ...... : ::::: . .... : .
XP_016 QRHATALEEL------SEQLEQAKRFKAN-LEKNKQGLETDNKELACEVKVLQQVKAESE
1210 1220 1230 1240 1250 1260
620 630 640 650 660 670
pF1KB9 RKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEI-EKSSKQRAMLAGATAVYSQFITQLTD
.:...:.. ..: :. :::. :. ::.:: . : ..... . .
XP_016 HKRKKLDAQVQELHAKV------SEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK
1270 1280 1290 1300 1310
680 690 700 710 720 730
pF1KB9 ENQSCCPVCQRVFQTEAELQEVIS---DLQSKLR-LAPDKLKSTESELKKKEKRRDEMLG
.. . ... .:. ::: .:.:..: : .: . :.. ...: :..
XP_016 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ
1320 1330 1340 1350 1360 1370
740 750 760 770 780
pF1KB9 LVPMRQSIIDLKEK------EIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESA
.. ..... : :.: : :.. ... .: . :.. .::. . ..
XP_016 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL
1380 1390 1400 1410 1420 1430
790 800 810 820 830
pF1KB9 KVCLTDVTIMERFQME----LKDVERKIAQQAAKLQGIDLDRTVQQ--VNQEKQEKQHKL
. : :.:. : . :. ..:. : :. ..:. . .. .. : .::. :
XP_016 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA
1440 1450 1460 1470 1480 1490
840 850 860 870 880 890
pF1KB9 DTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQR----RQQLEEQTVELS
... .: . .. ..: ..:.. ..: : : ... :... .. ::.:. :.
XP_016 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR
1500 1510 1520 1530 1540 1550
900 910 920 930 940 950
pF1KB9 TEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIH
:... : :.. ... ::.... .. . :. .. .. .: ..: . ..:....
XP_016 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN---EEKKRLLIKQVRELE
1560 1570 1580 1590 1600 1610
960 970 980 990 1000 1010
pF1KB9 GYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMR-LMRQDIDTQKIQ
. ..: : . ::. : .:. . ::. .: .... ...: :. : : :.
XP_016 AELED-ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL
1620 1630 1640 1650 1660 1670
1020 1030 1040 1050 1060
pF1KB9 E--RWLQDNLTLRKRNEE--LKEVEEERKQHLKEMGQMQVLQMKSEHQK--LEENIDNIK
: : .:.. .... : :: .: : : .:... . . ..:... : ..: :
XP_016 EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA
1680 1690 1700 1710 1720 1730
1070 1080 1090 1100 1110 1120
pF1KB9 RNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTL
... : ... : .: ....::.: :
XP_016 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ
1740 1750 1760 1770 1780 1790
1312 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:32:02 2016 done: Tue Nov 8 16:32:04 2016
Total Scan time: 14.150 Total Display time: 0.430
Function used was FASTA [36.3.4 Apr, 2011]