FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9016, 261 aa
  1>>>pF1KB9016 261 - 261 aa - 261 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.3252+/-0.000444; mu= -8.4903+/- 0.028
 mean_var=564.3204+/-118.851, 0's: 0 Z-trim(124.7): 6  B-trim: 855 in 1/60
 Lambda= 0.053990
 statistics sampled from 46763 (46777) to 46763 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.548), width:  16
 Scan time:  8.080

The best scores are:                                      opt bits E(85289)
NP_036610 (OMIM: 606962) WW domain-binding protein ( 261) 1859 158.3 1.3e-38
NP_001317428 (OMIM: 606962) WW domain-binding prot ( 216)  971 89.0 7.6e-18
NP_689826 (OMIM: 610981) postacrosomal sheath WW d ( 309)  495 52.2 1.4e-06


>>NP_036610 (OMIM: 606962) WW domain-binding protein 2 i  (261 aa)
 initn: 1859 init1: 1859 opt: 1859  Z-score: 814.3  bits: 158.3 E(85289): 1.3e-38
Smith-Waterman score: 1859; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)

               10        20        30        40        50        60
pF1KB9 MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV
              190       200       210       220       230       240

              250       260 
pF1KB9 YMPTSQPPPPPYYPPEDKKTQ
       :::::::::::::::::::::
NP_036 YMPTSQPPPPPYYPPEDKKTQ
              250       260 

>>NP_001317428 (OMIM: 606962) WW domain-binding protein   (216 aa)
 initn: 1066 init1: 883 opt: 971  Z-score: 441.4  bits: 89.0 E(85289): 7.6e-18
Smith-Waterman score: 1405; 82.8% identity (82.8% similar) in 261 aa overlap (1-261:1-216)

               10        20        30        40        50        60
pF1KB9 MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY
       ::::::::::::                                             :::
NP_001 EFGQRMLQVASQ---------------------------------------------EFY
              130                                                  

              190       200       210       220       230       240
pF1KB9 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV
         140       150       160       170       180       190     

              250       260 
pF1KB9 YMPTSQPPPPPYYPPEDKKTQ
       :::::::::::::::::::::
NP_001 YMPTSQPPPPPYYPPEDKKTQ
         200       210      

>>NP_689826 (OMIM: 610981) postacrosomal sheath WW domai  (309 aa)
 initn: 436 init1: 293 opt: 495  Z-score: 239.3  bits: 52.2 E(85289): 1.4e-06
Smith-Waterman score: 509; 37.9% identity (59.2% similar) in 277 aa overlap (1-253:1-273)

               10         20        30        40        50         
pF1KB9 MALNKNHSEGG-GVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIF
       ::.:..:.:.  :... : ::.:    .:::.: . ..  ..:.: : ::..:: :::::
NP_689 MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIF
               10        20        30        40        50        60

      60          70        80        90       100       110       
pF1KB9 LSKGK--DAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAG
       ... .  : : :::::: :: .  ..::::.::.::::..:   :::::.:..::.:  :
NP_689 ITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNG
               70        80        90       100       110       120

       120       130       140       150                160        
pF1KB9 GAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYP-------P--PVANGMYPCPP
        ::::.: :...:: :.::  :  . .  .   : ::         :  : .  .:  ::
NP_689 DAIEFAQLMVKAASAAARG-FPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPP
              130        140       150       160       170         

       170       180         190       200          210       220  
pF1KB9 -GYPYPPPPPEFYPGPPMMDGA--MGYVQPPPPPYPGPME---PPVSGPDVPSTPAAEAK
        ::  :::    : .::   ::  .:   ::     .:..   ::..    :.  .:   
NP_689 AGYGAPPPG---YGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPPAGYGAPPL
     180          190       200       210       220       230      

            230           240         250       260                
pF1KB9 AAEAAASAYYNP----GNPHNVYM--PTSQPPPPPYYPPEDKKTQ               
       .  :   .: .:    : :   :   :...  ::  :                       
NP_689 GYGAPPLGYGTPPLGYGAPPLGYGAPPAGNEGPPAGYRASPAGSGARPQESTAAQAPENE
        240       250       260       270       280       290      

NP_689 ASLPSASSSQVHS
        300         




261 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:58:32 2016 done: Fri Nov  4 16:58:33 2016
 Total Scan time:  8.080 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]