Result of FASTA (omim) for
pF1KB8997
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8997, 408 aa
1>>>pF1KB8997 408 - 408 aa - 408 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7313+/-0.000337; mu= 14.9419+/- 0.021
mean_var=72.9829+/-15.002, 0's: 0 Z-trim(115.8): 74 B-trim: 1112 in 1/48
Lambda= 0.150129
statistics sampled from 26375 (26454) to 26375 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.31), width: 16
Scan time: 6.750
The best scores are: opt bits E(85289)
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 2799 615.4 7.9e-176
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 2799 615.4 7.9e-176
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 2799 615.4 7.9e-176
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 2799 615.4 7.9e-176
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 2390 526.8 3.2e-149
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 2390 526.8 3.2e-149
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 1546 344.0 3.8e-94
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 1148 257.7 2.2e-68
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 566 131.8 3e-30
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 524 122.7 1.8e-27
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 507 119.0 2.4e-26
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 487 114.7 5.3e-25
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 474 111.7 1.9e-24
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 477 112.5 2.2e-24
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 475 112.1 3.2e-24
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 475 112.1 3.2e-24
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 475 112.1 3.2e-24
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 471 111.2 5.2e-24
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 460 108.8 2.3e-23
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 449 106.4 1.4e-22
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 411 98.2 4.1e-20
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 409 97.8 6e-20
XP_011540324 (OMIM: 602284) PREDICTED: bone morpho ( 357) 396 94.9 3.3e-19
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 389 93.4 1.1e-18
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 386 92.8 1.9e-18
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 379 91.2 4.2e-18
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 361 87.4 7.4e-17
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 361 87.4 7.4e-17
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 361 87.4 8.3e-17
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 361 87.4 9.2e-17
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 352 85.3 1.6e-16
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 345 83.9 7.3e-16
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392) 343 83.5 1e-15
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 328 80.2 1e-14
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 321 78.7 2.5e-14
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 295 73.0 1e-12
NP_001275756 (OMIM: 601918) growth/differentiation ( 366) 295 73.0 1.3e-12
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 295 73.0 1.3e-12
NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 295 73.0 1.3e-12
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 295 73.0 1.3e-12
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 295 73.0 1.3e-12
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 295 73.0 1.3e-12
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 295 73.0 1.3e-12
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 295 73.0 1.3e-12
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 295 73.0 1.3e-12
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 294 72.8 1.5e-12
XP_011541610 (OMIM: 601918) PREDICTED: growth/diff ( 454) 295 73.1 1.6e-12
NP_005251 (OMIM: 601918) growth/differentiation fa ( 454) 295 73.1 1.6e-12
XP_016857644 (OMIM: 602284) PREDICTED: bone morpho ( 382) 279 69.6 1.5e-11
NP_005250 (OMIM: 601788,614160) growth/differentia ( 375) 274 68.5 3.1e-11
>>XP_016877092 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 2799 init1: 2799 opt: 2799 Z-score: 3277.7 bits: 615.4 E(85289): 7.9e-176
Smith-Waterman score: 2799; 99.8% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KB8 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HHEEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDWERGFHRINI
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_016 HHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFHRINI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
310 320 330 340 350 360
370 380 390 400
pF1KB8 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
370 380 390 400
>>XP_005268072 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 2799 init1: 2799 opt: 2799 Z-score: 3277.7 bits: 615.4 E(85289): 7.9e-176
Smith-Waterman score: 2799; 99.8% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KB8 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HHEEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDWERGFHRINI
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_005 HHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFHRINI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
310 320 330 340 350 360
370 380 390 400
pF1KB8 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
370 380 390 400
>>NP_001193 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 2799 init1: 2799 opt: 2799 Z-score: 3277.7 bits: 615.4 E(85289): 7.9e-176
Smith-Waterman score: 2799; 99.8% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KB8 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HHEEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDWERGFHRINI
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_001 HHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFHRINI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
310 320 330 340 350 360
370 380 390 400
pF1KB8 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
370 380 390 400
>>NP_570911 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 2799 init1: 2799 opt: 2799 Z-score: 3277.7 bits: 615.4 E(85289): 7.9e-176
Smith-Waterman score: 2799; 99.8% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KB8 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 LLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HHEEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDWERGFHRINI
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_570 HHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFHRINI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 YEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 LHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 ARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL
310 320 330 340 350 360
370 380 390 400
pF1KB8 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 VNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
370 380 390 400
>>XP_016877093 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 2390 init1: 2390 opt: 2390 Z-score: 2800.0 bits: 526.8 E(85289): 3.2e-149
Smith-Waterman score: 2390; 99.7% identity (100.0% similar) in 345 aa overlap (64-408:1-345)
40 50 60 70 80 90
pF1KB8 KVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
::::::::::::::::::::::::::::::
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
10 20 30
100 110 120 130 140 150
pF1KB8 EEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 EEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 SSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWE
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB8 TFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLV
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 TFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQ
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 AFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVV
280 290 300 310 320 330
400
pF1KB8 LKNYQEMVVEGCGCR
:::::::::::::::
XP_016 LKNYQEMVVEGCGCR
340
>>XP_016877094 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 2390 init1: 2390 opt: 2390 Z-score: 2800.0 bits: 526.8 E(85289): 3.2e-149
Smith-Waterman score: 2390; 99.7% identity (100.0% similar) in 345 aa overlap (64-408:1-345)
40 50 60 70 80 90
pF1KB8 KVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
::::::::::::::::::::::::::::::
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
10 20 30
100 110 120 130 140 150
pF1KB8 EEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 EEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 SSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWE
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB8 TFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLV
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 TFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQ
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 AFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVV
280 290 300 310 320 330
400
pF1KB8 LKNYQEMVVEGCGCR
:::::::::::::::
XP_016 LKNYQEMVVEGCGCR
340
>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene (396 aa)
initn: 947 init1: 687 opt: 1546 Z-score: 1811.2 bits: 344.0 E(85289): 3.8e-94
Smith-Waterman score: 1648; 62.8% identity (82.0% similar) in 411 aa overlap (1-408:1-396)
10 20 30 40 50
pF1KB8 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
:. :.: :...:: ::::::: :.:.:: :..: : ..:: :.: : :.: .::
NP_001 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
::.::::..:: ::..::.: :: :::: .:: : : . .. :: ::::::::
NP_001 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDWERGFH-R
:::::: ::..: :: ... ::.::::::: .: :.::::..::::.... . .:: :
NP_001 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
:::::..:: : . .:::::::::..:..:::.:::.:::.::: . . :.:...:
NP_001 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
180 190 200 210 220
240 250 260 270 280 290
pF1KB8 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
:.::.. . . .:::::::: : .:.:.:::::::::::.:: : ..: ::. ::.
NP_001 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB8 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
:: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
NP_001 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
290 300 310 320 330 340
360 370 380 390 400
pF1KB8 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
:::::::::.::::::::::::::::::::: .::::::::.:::::::::
NP_001 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
350 360 370 380 390
>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b (240 aa)
initn: 743 init1: 687 opt: 1148 Z-score: 1348.7 bits: 257.7 E(85289): 2.2e-68
Smith-Waterman score: 1148; 70.8% identity (87.6% similar) in 233 aa overlap (176-408:13-240)
150 160 170 180 190 200
pF1KB8 SIPENEAISSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRLLDTRLV
:::::::..:: : . .:::::::::
XP_011 MQDALGNNSSFHHRINIYEIIKP-ATANSKFPVTRLLDTRLV
10 20 30 40
210 220 230 240 250 260
pF1KB8 HHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNW
..:..:::.:::.:::.::: . . :.:...::.::.. . . .:::::::: : .:
XP_011 NQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSW
50 60 70 80 90 100
270 280 290 300 310 320
pF1KB8 AQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDW
.:.:::::::::::.:: : ..: ::. ::. :: : :. .:.:: :::::::::::::
XP_011 SQIRPLLVTFGHDGKGHPL--HKREKRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDW
110 120 130 140 150
330 340 350 360 370 380
pF1KB8 IVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLY
:::::::.::::::.::::::::::::::::::::::::::.::::::::::::::::::
XP_011 IVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLY
160 170 180 190 200 210
390 400
pF1KB8 LDEYDKVVLKNYQEMVVEGCGCR
::: .::::::::.:::::::::
XP_011 LDENEKVVLKNYQDMVVEGCGCR
220 230 240
>>NP_001711 (OMIM: 602284) bone morphogenetic protein 8B (402 aa)
initn: 613 init1: 285 opt: 566 Z-score: 663.9 bits: 131.8 E(85289): 3e-30
Smith-Waterman score: 637; 31.6% identity (59.7% similar) in 434 aa overlap (2-407:4-401)
10 20 30 40 50
pF1KB8 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFE
.:: :. . :: :::.. .: : : . :: : .. :: .
NP_001 MTALPGPLWLLGLALCA--LGGGG-PGLRPPPGCPQ----------RRLGARER--RDVQ
10 20 30 40
60 70 80 90 100 110
pF1KB8 ATLLQMFGLRRRPQPSKS-------AVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPA
.: ..:: ::.: : : .: :::. ..:...:. . ::
NP_001 REILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLYHAMAGDDDEDGAPA------ERRL
50 60 70 80 90
120 130 140 150 160 170
pF1KB8 SRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDW
.::. : :: . . . : .: .: :.:..:: .::...::.:... : .
NP_001 GRADLVMSFVNMVERDRALGHQEPHWKEFRFDLTQIPAGEAVTAAEFRIYK--VPSIHLL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 ERGFHRINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPN
.: .: .....:.. .. . :. .:: . .. . : ..::. : : ... .
NP_001 NRTLH-VSMFQVVQEQSNR-ESDLF--FLDLQTLRAGDEGWLVLDVTAASDCWLLKRHKD
160 170 180 190 200 210
240 250 260 270 280
pF1KB8 YGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALT------
:: . : .:..:. : . . :. . .:..::: . . . :
NP_001 LGLRLYV------ETEDGHSVDPGLAGLLGQRAPRSQQPFVVTFFRASPSPIRTPRAVRP
220 230 240 250 260
290 300 310 320 330
pF1KB8 -RRRRAKRS---PKH----------HSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPG
:::. :.: :. :....: . :::: :::.:.:.:: ::..:: :
NP_001 LRRRQPKKSNELPQANRLPGIFDDVHGSHGR---QVCRRHELYVSFQDLGWLDWVIAPQG
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB8 YQAFYCHGDCPFPLADHLNSTNHAIVQTLVN-SVNSSIPKACCVPTELSAISMLYLDEYD
:.:.::.:.: ::: . .:.:::::.:.::. . ...:::::.::.::: :.:: : .
NP_001 YSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPDAVPKACCAPTKLSATSVLYYDSSN
330 340 350 360 370 380
400
pF1KB8 KVVLKNYQEMVVEGCGCR
.:.:.....:::..:::
NP_001 NVILRKHRNMVVKACGCH
390 400
>>NP_001710 (OMIM: 112267) bone morphogenetic protein 7 (431 aa)
initn: 669 init1: 273 opt: 524 Z-score: 614.3 bits: 122.7 E(85289): 1.8e-27
Smith-Waterman score: 669; 33.3% identity (60.0% similar) in 402 aa overlap (46-407:47-430)
20 30 40 50 60 70
pF1KB8 VLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQP--
:: . .:. :. .:...:: .::.:
NP_001 LWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQRE----ILSILGLPHRPRPHL
20 30 40 50 60 70
80 90 100 110
pF1KB8 -SKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPA-----------------SRAN
.: : .: ::: .. :: . :. :: . . . :.
NP_001 QGKHNSAPMFMLDLYNAMA-VEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLTDAD
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB8 TVRSFHH--EEHLENIPGTSENSAFRFLFNLSSIPENEAISSAELRLFREQVDQGPDWER
: :: . :. : . .. ::: .::.:::.::...::.:.... . . : :
NP_001 MVMSFVNLVEHDKEFFHPRYHHREFRF--DLSKIPEGEAVTAAEFRIYKDYIRERFDNET
140 150 160 170 180
180 190 200 210 220 230
pF1KB8 GFHRINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYG
::..:.:.. : . . :::.: . . : .::.. . .:. . . : :
NP_001 --FRISVYQVLQ---EHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLG
190 200 210 220 230 240
240 250 260 270 280
pF1KB8 LAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGH------ALTRR
: . : : . :.: ::.. .:..:.: . . : . ...
NP_001 LQLSVETLDGQSINPKLAGLIGRHGPQNK------QPFMVAFFKATEVHFRSIRSTGSKQ
250 260 270 280 290
290 300 310 320 330
pF1KB8 RRAKRSPKHHSQRA-RKKN----------KNCRRHSLYVDFSDVGWNDWIVAPPGYQAFY
: .:: ..:.: : : . :..: :::.: :.::.:::.:: :: :.:
NP_001 RSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYY
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB8 CHGDCPFPLADHLNSTNHAIVQTLVNSVNS-SIPKACCVPTELSAISMLYLDEYDKVVLK
:.:.: ::: ...:.::::::::::. .: ..:: ::.::.:.:::.::.:. ..:.::
NP_001 CEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILK
360 370 380 390 400 410
400
pF1KB8 NYQEMVVEGCGCR
.:..:::..:::
NP_001 KYRNMVVRACGCH
420 430
408 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:56:07 2016 done: Fri Nov 4 16:56:08 2016
Total Scan time: 6.750 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]