Result of FASTA (omim) for
pF1KB8994
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8994, 329 aa
1>>>pF1KB8994 329 - 329 aa - 329 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4839+/-0.000305; mu= 21.9638+/- 0.019
mean_var=96.9709+/-22.702, 0's: 0 Z-trim(118.3): 164 B-trim: 1877 in 1/50
Lambda= 0.130243
statistics sampled from 30887 (31125) to 30887 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.365), width: 16
Scan time: 7.750
The best scores are: opt bits E(85289)
NP_001308879 (OMIM: 610147) G-protein coupled bile ( 330) 2204 424.1 1.9e-118
NP_001070659 (OMIM: 610147) G-protein coupled bile ( 330) 2204 424.1 1.9e-118
XP_016858957 (OMIM: 610147) PREDICTED: G-protein c ( 330) 2204 424.1 1.9e-118
XP_016858956 (OMIM: 610147) PREDICTED: G-protein c ( 330) 2204 424.1 1.9e-118
NP_733800 (OMIM: 610147) G-protein coupled bile ac ( 330) 2204 424.1 1.9e-118
NP_001070662 (OMIM: 610147) G-protein coupled bile ( 330) 2204 424.1 1.9e-118
XP_016858958 (OMIM: 610147) PREDICTED: G-protein c ( 330) 2204 424.1 1.9e-118
XP_011509045 (OMIM: 610147) PREDICTED: G-protein c ( 330) 2204 424.1 1.9e-118
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 230 53.3 9.3e-07
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 230 53.3 9.3e-07
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 230 53.3 9.8e-07
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 230 53.4 1e-06
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 230 53.4 1e-06
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 230 53.4 1e-06
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 230 53.4 1e-06
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 230 53.4 1e-06
NP_003766 (OMIM: 603751) sphingosine 1-phosphate r ( 384) 208 49.2 1.7e-05
NP_001159687 (OMIM: 605146) sphingosine 1-phosphat ( 398) 204 48.4 2.9e-05
NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398) 204 48.4 2.9e-05
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382) 202 48.0 3.7e-05
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382) 202 48.0 3.7e-05
XP_016869883 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869882 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869887 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869876 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869888 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869879 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869894 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869878 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869889 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869881 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869892 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
NP_001392 (OMIM: 602282) lysophosphatidic acid rec ( 364) 201 47.8 4.1e-05
XP_016869884 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869885 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869886 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869875 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869896 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869891 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_005251839 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869890 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869873 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869895 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_005251838 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869880 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869877 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
NP_476500 (OMIM: 602282) lysophosphatidic acid rec ( 364) 201 47.8 4.1e-05
XP_016869874 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869872 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
XP_016869893 (OMIM: 602282) PREDICTED: lysophospha ( 364) 201 47.8 4.1e-05
>>NP_001308879 (OMIM: 610147) G-protein coupled bile aci (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
NP_001 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>NP_001070659 (OMIM: 610147) G-protein coupled bile aci (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
NP_001 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>XP_016858957 (OMIM: 610147) PREDICTED: G-protein coupl (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
XP_016 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>XP_016858956 (OMIM: 610147) PREDICTED: G-protein coupl (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
XP_016 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>NP_733800 (OMIM: 610147) G-protein coupled bile acid r (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
NP_733 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>NP_001070662 (OMIM: 610147) G-protein coupled bile aci (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
NP_001 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>XP_016858958 (OMIM: 610147) PREDICTED: G-protein coupl (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
XP_016 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>XP_011509045 (OMIM: 610147) PREDICTED: G-protein coupl (330 aa)
initn: 2202 init1: 1774 opt: 2204 Z-score: 2247.3 bits: 424.1 E(85289): 1.9e-118
Smith-Waterman score: 2204; 99.7% identity (99.7% similar) in 330 aa overlap (1-329:1-330)
10 20 30 40 50 60
pF1KB8 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTPNSTGEVPSPIPKGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 GLLTGLALP-LPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSIRLALLLTWAGPLLFASLPALGWNHWTPGANCSSQAIFPAPYLYLEVYGLLLPAVGA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQ
250 260 270 280 290 300
300 310 320
pF1KB8 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
::::::::::::::::::::::::::::::
XP_011 GLWGRASRDSPGPSIAYHPSSQSSVDLDLN
310 320 330
>>NP_071640 (OMIM: 142703) histamine H2 receptor isoform (359 aa)
initn: 190 init1: 64 opt: 230 Z-score: 242.3 bits: 53.3 E(85289): 9.3e-07
Smith-Waterman score: 233; 27.4% identity (56.2% similar) in 299 aa overlap (1-277:1-286)
10 20 30 40 50
pF1KB8 MTPNSTGE---VPSPIPKGALGLSLALASLIITA-NLLLALGIAWDRRLRSPPAGCFFLS
:.::.:. . : : .. . ::. :: .: :... :... .::::. ..::..:
NP_071 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVS
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LLLAGLLTGL-ALPLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLA-----NLLLVHGERY
: .. :: :: .::. .... : . :: :. :. .: ::... .::
NP_071 LAITDLLLGLLVLPFSAIYQLSCK--WSFGKVFCNIYTSLDVMLCTASILNLFMISLDRY
60 70 80 90 100 110
120 130 140 150 160
pF1KB8 MAVLRPLQPP---GSIRLA--LLLTWAGPLLFASLPA-LGWN---HWTPGANCSSQAIFP
::. ::. : .:.: :.: :. . .. : :::: . . : . .:.
NP_071 CAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 APYLYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQ
. :::::. : . .: . .. .. .. . : ..: .. :. .: : :.
NP_071 VN----EVYGLVDGLV--TFYLPLLIMCITYYRIFKVAR-DQAKRINHISSW-KAATIRE
180 190 200 210 220
230 240 250 260 270
pF1KB8 ARAQ---AGAMLLFGLCWGPYVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVA
.: :..: : .:: :: .... : .. .. .: :: :..: :.
NP_071 HKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDD--AINEVLEAIVLWLGYANSALNPIL
230 240 250 260 270 280
280 290 300 310 320
pF1KB8 MGLGDQRYTAPWRAAAQRCLQGLWGRASRDSPGPSIAYHPSSQSSVDLDLN
NP_071 YAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSG
290 300 310 320 330 340
>>XP_006714928 (OMIM: 142703) PREDICTED: histamine H2 re (362 aa)
initn: 190 init1: 64 opt: 230 Z-score: 242.3 bits: 53.3 E(85289): 9.3e-07
Smith-Waterman score: 233; 27.4% identity (56.2% similar) in 299 aa overlap (1-277:1-286)
10 20 30 40 50
pF1KB8 MTPNSTGE---VPSPIPKGALGLSLALASLIITA-NLLLALGIAWDRRLRSPPAGCFFLS
:.::.:. . : : .. . ::. :: .: :... :... .::::. ..::..:
XP_006 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVS
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 LLLAGLLTGL-ALPLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLA-----NLLLVHGERY
: .. :: :: .::. .... : . :: :. :. .: ::... .::
XP_006 LAITDLLLGLLVLPFSAIYQLSCK--WSFGKVFCNIYTSLDVMLCTASILNLFMISLDRY
60 70 80 90 100 110
120 130 140 150 160
pF1KB8 MAVLRPLQPP---GSIRLA--LLLTWAGPLLFASLPA-LGWN---HWTPGANCSSQAIFP
::. ::. : .:.: :.: :. . .. : :::: . . : . .:.
XP_006 CAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 APYLYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQ
. :::::. : . .: . .. .. .. . : ..: .. :. .: : :.
XP_006 VN----EVYGLVDGLV--TFYLPLLIMCITYYRIFKVAR-DQAKRINHISSW-KAATIRE
180 190 200 210 220
230 240 250 260 270
pF1KB8 ARAQ---AGAMLLFGLCWGPYVATLLLSVLAYEQRPPLGPGTLLSLLSLGSASAAAVPVA
.: :..: : .:: :: .... : .. .. .: :: :..: :.
XP_006 HKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDD--AINEVLEAIVLWLGYANSALNPIL
230 240 250 260 270 280
280 290 300 310 320
pF1KB8 MGLGDQRYTAPWRAAAQRCLQGLWGRASRDSPGPSIAYHPSSQSSVDLDLN
XP_006 YAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSG
290 300 310 320 330 340
329 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:55:29 2016 done: Fri Nov 4 16:55:30 2016
Total Scan time: 7.750 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]