FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8989, 390 aa
  1>>>pF1KB8989 390 - 390 aa - 390 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2826+/-0.000448; mu= 4.0918+/- 0.028
 mean_var=198.6037+/-39.453, 0's: 0 Z-trim(117.4): 5  B-trim: 419 in 1/51
 Lambda= 0.091008
 statistics sampled from 29293 (29296) to 29293 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.343), width:  16
 Scan time:  9.060

The best scores are:                                      opt bits E(85289)
NP_036364 (OMIM: 603198,613327) polymerase I and t ( 390) 2422 330.6   4e-90
XP_005257299 (OMIM: 603198,613327) PREDICTED: poly ( 225)  991 142.5 9.6e-34
NP_004648 (OMIM: 606728) serum deprivation-respons ( 425)  647 97.5 6.1e-20


>>NP_036364 (OMIM: 603198,613327) polymerase I and trans  (390 aa)
 initn: 2422 init1: 2422 opt: 2422  Z-score: 1739.0  bits: 330.6 E(85289): 4e-90
Smith-Waterman score: 2422; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390)

               10        20        30        40        50        60
pF1KB8 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 MEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 FTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGD
              310       320       330       340       350       360

              370       380       390
pF1KB8 LRRGSSPDVHALLEITEESDAVLVDKSDSD
       ::::::::::::::::::::::::::::::
NP_036 LRRGSSPDVHALLEITEESDAVLVDKSDSD
              370       380       390

>>XP_005257299 (OMIM: 603198,613327) PREDICTED: polymera  (225 aa)
 initn: 988 init1: 988 opt: 991  Z-score: 726.8  bits: 142.5 E(85289): 9.6e-34
Smith-Waterman score: 991; 86.2% identity (89.2% similar) in 195 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB8 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVN
               70        80        90       100       110       120

              130       140       150       160         170        
pF1KB8 VKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVK--LPAKLSISKSLKESEAL
       ::::::::::::::::::::::::::::::::::::: . :   :. :.  : .  .  :
XP_005 VKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQPKKKPNAPSDLATPKIVPFD--L
              130       140       150       160       170          

      180       190       200       210       220       230        
pF1KB8 PEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSK
       :: :  .:     ::                                             
XP_005 PETEPFDLKPETVPELPPFDQTPRALPYYPEPGPRPTPEELTAGGSV             
      180       190       200       210       220                  

>>NP_004648 (OMIM: 606728) serum deprivation-response pr  (425 aa)
 initn: 680 init1: 418 opt: 647  Z-score: 479.0  bits: 97.5 E(85289): 6.1e-20
Smith-Waterman score: 703; 38.5% identity (67.5% similar) in 382 aa overlap (14-379:14-355)

               10        20        30            40         50     
pF1KB8 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGA----GSEELIKSD-QVNGVLVL
                    ::  : .  .::: . . .  :: .    ..:: :... :::.: ::
NP_004 MGEDAAQAEKFQHPG-SDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVL
               10         20        30        40        50         

          60        70        80        90       100       110     
pF1KB8 SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR
       .::::... .: .: .: ..:.::  .::.:..::..:.::.: .:.::::::::::: :
NP_004 TLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSR
      60        70        80        90       100       110         

         120       130       140       150       160       170     
pF1KB8 KVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKES
       :::.....:.  ..:: .:.:.:: :.:.:::: .:::.:.:.: ..::.. ... .  :
NP_004 KVSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPV--S
     120       130       140       150       160       170         

         180       190       200                210       220      
pF1KB8 EALPEKEGEELGEGERPEEDAAALELSSD-------EAVE--VEEVIEESRAERIKRSGL
        :.  :: :   :..  ::   ...::::       ::.:  .:: .::::::.::::.:
NP_004 GAVEGKE-ELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSL
       180        190       200       210       220       230      

        230       240       250       260       270       280      
pF1KB8 RRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER
       ..::..:::::                             :...::.::::::..: .::
NP_004 KKVDSLKKAFS-----------------------------RQNIEKKMNKLGTKIVSVER
        240                                    250       260       

        290       300       310       320       330       340      
pF1KB8 REKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGA
       :::.:       ::.: .:   . .:.. .:: :.::  ::.:::. .. . :.  .. .
NP_004 REKIK-------KSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSEDLPS
       270              280       290       300       310       320

        350       360       370         380       390              
pF1KB8 DDDEGGAERGEAGDLRRGSSPDVHALLE--ITEESDAVLVDKSDSD              
       ...  . .. :.    .. .  . ::.:  :.::.                         
NP_004 SEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKATSRGSNSGMDSNIDLTIVEDE
              330       340       350       360       370       380

NP_004 EEESVALEQAQKVRYEGSYALTSEEAERSDGDPVQPAVLQVHQTS
              390       400       410       420     




390 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:52:34 2016 done: Fri Nov  4 16:52:36 2016
 Total Scan time:  9.060 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]