Result of FASTA (omim) for
pF1KB8988
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8988, 388 aa
1>>>pF1KB8988 388 - 388 aa - 388 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3464+/-0.000329; mu= 0.3845+/- 0.021
mean_var=277.7676+/-56.458, 0's: 0 Z-trim(124.7): 156 B-trim: 36 in 1/54
Lambda= 0.076954
statistics sampled from 46631 (46796) to 46631 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.836), E-opt: 0.2 (0.549), width: 16
Scan time: 9.660
The best scores are: opt bits E(85289)
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 2730 315.8 1.1e-85
NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 847 106.7 1e-22
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 559 74.7 4.1e-13
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 461 64.0 9.4e-10
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 430 60.4 8.4e-09
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 408 57.8 3.2e-08
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 408 58.0 5e-08
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 405 57.7 6.5e-08
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315) 397 56.7 9.1e-08
NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 400 57.1 9.2e-08
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 394 56.5 1.5e-07
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 384 55.1 2e-07
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 386 55.4 2.1e-07
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 365 53.1 9.8e-07
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474) 369 53.7 1.1e-06
NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 358 52.4 2.1e-06
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 352 51.5 2.1e-06
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 358 52.4 2.2e-06
NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 358 52.6 3.1e-06
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 358 52.7 3.3e-06
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 358 52.7 3.3e-06
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 358 52.7 3.3e-06
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 358 52.7 3.3e-06
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 358 52.7 3.3e-06
NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 358 52.7 3.4e-06
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 358 52.7 3.4e-06
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 358 52.7 3.4e-06
NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 358 52.7 3.4e-06
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 358 52.7 3.4e-06
NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 358 52.7 3.4e-06
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 358 52.7 3.4e-06
NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 358 52.7 3.5e-06
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 358 52.7 3.5e-06
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 358 52.7 3.6e-06
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 358 52.7 3.6e-06
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 346 51.3 7.5e-06
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 346 51.3 7.6e-06
NP_848511 (OMIM: 606698) transcription factor SOX- ( 753) 343 51.0 1.1e-05
XP_011532722 (OMIM: 606698) PREDICTED: transcripti ( 448) 335 49.9 1.4e-05
NP_001295094 (OMIM: 606698) transcription factor S ( 448) 335 49.9 1.4e-05
XP_005265860 (OMIM: 606698) PREDICTED: transcripti ( 448) 335 49.9 1.4e-05
NP_001139283 (OMIM: 607257) transcription factor S ( 801) 337 50.4 1.8e-05
>>NP_113627 (OMIM: 612202) transcription factor SOX-7 [H (388 aa)
initn: 2730 init1: 2730 opt: 2730 Z-score: 1659.1 bits: 315.8 E(85289): 1.1e-85
Smith-Waterman score: 2730; 100.0% identity (100.0% similar) in 388 aa overlap (1-388:1-388)
10 20 30 40 50 60
pF1KB8 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 KRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 QAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 QAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 GPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 PYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 GQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQV
310 320 330 340 350 360
370 380
pF1KB8 TPTGPTETSLISVLADATATYYNSYSVS
::::::::::::::::::::::::::::
NP_113 TPTGPTETSLISVLADATATYYNSYSVS
370 380
>>NP_071899 (OMIM: 610928,613674) transcription factor S (414 aa)
initn: 775 init1: 525 opt: 847 Z-score: 528.9 bits: 106.7 E(85289): 1e-22
Smith-Waterman score: 847; 43.3% identity (61.9% similar) in 404 aa overlap (5-385:27-411)
10 20 30
pF1KB8 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGD
:: :: :.: : : ... :..: : :
NP_071 MSSPDAGYASDDQSQTQSALPAVMAGLGPCPWAESLS-PIGDMKVK-GEAPANSGAPAGA
10 20 30 40 50
40 50 60 70 80 90
pF1KB8 KG---SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYV
: .::::::::::::::::::::::: :::::::::::::::::::::::..:::.:
NP_071 AGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFV
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB8 DEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNAL--PEKRSGSR
.::::::.:::::.:::::::::.::.::: :::. ::: .:.. : : :: .
NP_071 EEAERLRVQHMQDHPNYKYRPRRRKQVKRL-KRVEGGFL-HGLAEPQAAALGPEGGRVAM
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 GALGEKEDRGEYSPGTAL--PSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
.:: . . . : : : . : :.. . :.: .: :: :::: . ::::
NP_071 DGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSL----GAPP-LDGYP--LPTP-DTSPLD
180 190 200 210 220
220 230 240 250 260
pF1KB8 VLEPEQTFFSSP----CQEEHGHPRRI-------PHLPGHPYSPEYAPSPLHCSHPLGSL
..:. .::..: : . :. :. :. :. .: : : : : :
NP_071 GVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIP-GLL
230 240 250 260 270 280
270 280 290 300 310
pF1KB8 ALGQSPGV---SMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEH-PGFDALD
: .. : .: :: : . . .. :.. :: ::::: : :. :
NP_071 APPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQPSPPPEALPCRDGTD
290 300 310 320 330 340
320 330 340 350 360 370
pF1KB8 QLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLAD
. .::::..::.::.:::. .:. . . .:: : :. .. .. ::..:
NP_071 PSQPAELLGEVDRTEFEQYLHFVCKPEMG---LPYQGHD--SGVN-LPDSHGAISSVVSD
350 360 370 380 390 400
380
pF1KB8 AT-ATYYNSYSVS
:. :.:: .:
NP_071 ASSAVYYCNYPDV
410
>>NP_060889 (OMIM: 137940,601618,607823) transcription f (384 aa)
initn: 745 init1: 480 opt: 559 Z-score: 356.5 bits: 74.7 E(85289): 4.1e-13
Smith-Waterman score: 782; 41.6% identity (58.2% similar) in 409 aa overlap (2-388:30-383)
10 20 30
pF1KB8 MASLLGAYPWPEGLECPALDAELSDGQ-SPPA
:. : : .: :: : . : :::
NP_060 MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPR
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 VPRP------PGDKG-----SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLG
:.: :. .: .::::::::::::::::::::::: :::::::: ::::::
NP_060 SPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB8 KSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSR
:.:: :. ..:::.:.::::::.::..:.:::::::::::::.. .:..::.:: .:.
NP_060 KAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARK-ARRLEPGLLLPGLAP
130 140 150 160 170
150 160 170 180 190 200
pF1KB8 DQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYG
: :: .. : : :. ..: : : ... :
NP_060 PQPP-PEPFPAASG------------------SARA-FRELP--------PLGAEFDGLG
180 190 200 210
210 220 230 240 250
pF1KB8 LPTPPEMSPLDVLEP-EQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGS
:::: : :::: ::: : .:: : : : :. :::. : : :
NP_060 LPTP-ERSPLDGLEPGEAAFFPPPAAPEDCALR--------PFRAPYAPTELS-RDPGGC
220 230 240 250 260
260 270 280 290 300 310
pF1KB8 LALGQSPGVSMMSPVPGCPPSPAYY----SPATYHPLHSNLQAHLGQLSPPPEHPGFDAL
: . .. . :. : . :: .:. : : : :::::: : ...
NP_060 Y--GAPLAEALRTAPPAAPLAGLYYGTLGTPGPY-P---------GPLSPPPEAPPLESA
270 280 290 300
320 330 340 350 360 370
pF1KB8 DQLSQV-ELLGDMDRNEFDQYLN-TPGHPDSATGAMALSGHVPVSQVTPTG---PTETSL
. :. . .: .:.: .::::::: . .:: : : : :: .... : . : :.::
NP_060 EPLGPAADLWADVDLTEFDQYLNCSRTRPD-APG---LPYHVALAKLGPRAMSCPEESSL
310 320 330 340 350 360
380
pF1KB8 ISVLADATATYYNSYSVS
::.:.::... : : .:
NP_060 ISALSDASSAVYYSACISG
370 380
>>NP_000337 (OMIM: 114290,608160,616425) transcription f (509 aa)
initn: 479 init1: 383 opt: 461 Z-score: 296.1 bits: 64.0 E(85289): 9.4e-10
Smith-Waterman score: 461; 32.3% identity (54.7% similar) in 322 aa overlap (30-341:90-406)
10 20 30 40 50
pF1KB8 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDE
: : :.. .. ...::::::::::.
NP_000 LKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAA
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB8 RKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRK
:..:: : : :::::::: ::: :. :. :.:::.:.::::::.:: .:.:.:::.:::.
NP_000 RRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR
120 130 140 150 160 170
120 130 140 150 160 170
pF1KB8 KQAKRLCKRVDPGFLLSSLSRDQ--NALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGC
:..: ... . . .: . .:: : ....: .. ::.: . :
NP_000 KSVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPT
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB8 YHEGPAGGGGGGTPSSVDTYPYGLPTPP-EMSPLDVLEPEQTFFSSPCQEEHGHPRRIPH
. . : . : : :: .. .:. : . .:. : . .
NP_000 TPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISN--IETFDVNEFDQY
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 LP--GHPYSPE-YAPSPLHCSHPLGSLA-LGQSPGVSMMSP--VPGCPPS-PAYYSPATY
:: ::: : .. :. ..: : : : :: .: ::. : ::
NP_000 LPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQ
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB8 HPLHSNLQAHLGQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAM
: . . : : . ::..: .: ::. :. .:... .:.:
NP_000 APPQPQ-AAPPQQPAAPPQQPQAHTLTTLSSEP--GQSQRTHIKTEQLSPSHYSEQQQHS
360 370 380 390 400 410
350 360 370 380
pF1KB8 ALSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS
NP_000 PQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQR
420 430 440 450 460 470
>>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H (391 aa)
initn: 377 init1: 377 opt: 430 Z-score: 279.0 bits: 60.4 E(85289): 8.4e-09
Smith-Waterman score: 470; 31.9% identity (57.1% similar) in 301 aa overlap (37-325:43-324)
10 20 30 40 50 60
pF1KB8 AYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQ
: :....:..:::::::::.. .:...: .
NP_005 PGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQE
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB8 NPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLC
:: .::.:.:: :: ::... ..:::..:::.::: ::...:.:::::::: .: :
NP_005 NPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRK--TKTLL
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB8 KRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGG
:. : ::. : .:. :.: : . : : :.:.:..
NP_005 KK-DK----YSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRL--------ESPGGAA
140 150 160 170
190 200 210 220 230
pF1KB8 GGGTPS----SVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQ---EEHGHPRRIPHLPG
::: . .:: .. . . . . : . .. . : . :.:: . :: :
NP_005 GGGYAHVNGWANGAYPGSVAAAAAAAAM-MQEAQLAYGQHPGAGGAHPHAHPAH-PH-PH
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 HPYSPEYAPSPLHCSHPLGSLA---LGQSPGVSMMSP--VPGCPPSPAYYSPATYHPLHS
::.. . :.:.: . .:.: ...: : :: : : . : . :. :.
NP_005 HPHAHPHNPQPMH-RYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 NLQAHLGQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGH
: . . . .. :: .: . : :
NP_005 NSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEG
300 310 320 330 340 350
360 370 380
pF1KB8 VPVSQVTPTGPTETSLISVLADATATYYNSYSVS
NP_005 GDPAAAAAAAAQSRLHSLPQHYQGAGAGVNGTVPLTHI
360 370 380 390
>>NP_004180 (OMIM: 604747) transcription factor SOX-14 [ (240 aa)
initn: 390 init1: 369 opt: 408 Z-score: 268.5 bits: 57.8 E(85289): 3.2e-08
Smith-Waterman score: 408; 39.7% identity (59.3% similar) in 204 aa overlap (45-240:8-198)
20 30 40 50 60 70
pF1KB8 ECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAE
:.:::::::::.. .:...: .:: .::.:
NP_004 MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSE
10 20 30
80 90 100 110 120 130
pF1KB8 LSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFL
.:: :: :: :. ..::::.:::.::: :::...:.:::::::: : : :. :
NP_004 ISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKP--KNLLKKDRYVFP
40 50 60 70 80 90
140 150 160 170 180
pF1KB8 LSSLSRDQNALPEKRSG-----SRGALGEKEDRGEYSPGTALP-SLRGCYHEGPAGGGGG
: :. : . : : .: : : :. : . : .. : :: :: ...
NP_004 LPYLG-DTD--PLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLD-----PAQFSSS
100 110 120 130 140
190 200 210 220 230 240
pF1KB8 GTPSSVDTYPYGLPTP--PEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEY
. ... :. : : : : : . .: : :. : :: : ::.
NP_004 AI-QKMGEVPHTLATGALPYASTLGYQNGAFGSLSCPSQHTHTHPS--PTNPGYVVPCNC
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB8 APSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPP
NP_004 TAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM
210 220 230 240
>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H (446 aa)
initn: 473 init1: 386 opt: 408 Z-score: 265.0 bits: 58.0 E(85289): 5e-08
Smith-Waterman score: 419; 32.2% identity (49.6% similar) in 367 aa overlap (32-317:84-437)
10 20 30 40 50
pF1KB8 ASLLGAYPWPEGLECPALDAELSDGQSPPAVPRP--PGDKGS---ESRIRRPMNAFMVWA
:: : : :. . ...::::::::::
NP_055 GDPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWA
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB8 KDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRP
. :..:: : : :::::::: ::: :. :. :.:::.:.::::::.:: .:.:.:::.:
NP_055 QAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQP
120 130 140 150 160 170
120 130 140 150 160
pF1KB8 RRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYS----------
::.:.:: . : : :. .:. . ..: ::. . .:...
NP_055 RRRKSAKAGHSDSDSGAELGP-HPGGGAVYKAEAG----LGDGHHHGDHTGQTHGPPTPP
180 190 200 210 220
170 180 190
pF1KB8 --PGTAL------PSLRGCYHEG--PAGGGGG-----------------GTPSSVDTY--
: : : : :. :: :. .: :: .. :..
NP_055 TTPKTELQQAGAKPELK---LEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEF
230 240 250 260 270 280
200 210 220 230
pF1KB8 ----PYGLPTPPE-------------MSPLDVLEPEQTFFSSPCQEEHGHPRRIPHL---
: : :.::: ::. . . . .:: : : :: ::.
NP_055 DQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPT--ETGPPR--PHIKTE
290 300 310 320 330 340
240 250 260 270 280
pF1KB8 ---PGH-PYSPEYAPSPLHCSH--------PLGSLA-----LGQSPGVSMMSPVPGCPPS
::: .:. .:. :: : : .: :. . :... :: :.
NP_055 QPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPG
350 360 370 380 390 400
290 300 310 320 330 340
pF1KB8 PAYYSPATYHPLHSNLQAHLGQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPG
: : . : . . :. :. :: : . ::
NP_055 -LYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
410 420 430 440
350 360 370 380
pF1KB8 HPDSATGAMALSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS
>>NP_008872 (OMIM: 602229,609136,611584,613266) transcri (466 aa)
initn: 463 init1: 384 opt: 405 Z-score: 263.0 bits: 57.7 E(85289): 6.5e-08
Smith-Waterman score: 452; 30.0% identity (52.2% similar) in 404 aa overlap (21-386:77-451)
10 20 30 40
pF1KB8 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRP---PGDKGSESRIRR
... .: . :: : : . :. ...:
NP_008 GPGELGKVKKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKR
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB8 PMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQ
:::::::::. :..:: : : :::::::: ::: :. :. :.:::...::::::.:: .
NP_008 PMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKK
110 120 130 140 150 160
110 120 130 140 150
pF1KB8 DYPNYKYRPRRKK-----QAKRLCK--RVDPGFLLSSLSRDQNALPEKRS---GSRGALG
:.:.:::.:::.: :.. : ... : . .. ..: ..: :: . :
NP_008 DHPDYKYQPRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDG
170 180 190 200 210 220
160 170 180 190 200
pF1KB8 EKEDRGEYSPGTALPSL--RGCYHEGPAGG-------GGGGTP----SSVDTYPYGLPTP
. : . : : : . . : : : :: : ..:: . .
NP_008 NPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVM
230 240 250 260 270 280
210 220 230 240 250
pF1KB8 PEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLP--GHPYSPEYAPSPLHC---SHPLG-
.: .:: : .: . : .::: .. :. . : . : :.: :
NP_008 SNMETFDVAELDQ--YLPP----NGHPGHVSSYSAAGYGLGSALAVASGHSAWISKPPGV
290 300 310 320 330 340
260 270 280 290 300 310
pF1KB8 SLALGQSPGVSMMSPVP---GCPPSPAYYS--PATYHPLHSNLQ-AHLGQLSPPPEHPGF
.: . :::. . : . : .: .:. :.: . ...:. : :. : .: :
NP_008 ALPTVSPPGVDAKAQVKTETAGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQF
350 360 370 380 390 400
320 330 340 350 360 370
pF1KB8 DALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLIS
: :. . : . : :: .:.: . : . ::.. : .
NP_008 DYSDHQPS----GPY-------Y----GHSGQASGLY--------SAFSYMGPSQRPLYT
410 420 430
380
pF1KB8 VLADATATYYNSYSVS
...: . . .:.:
NP_008 AISDPSPSGPQSHSPTHWEQPVYTTLSRP
440 450 460
>>NP_008874 (OMIM: 601947) transcription factor SOX-12 [ (315 aa)
initn: 370 init1: 370 opt: 397 Z-score: 260.4 bits: 56.7 E(85289): 9.1e-08
Smith-Waterman score: 406; 34.2% identity (49.8% similar) in 307 aa overlap (25-291:12-305)
10 20 30 40 50
pF1KB8 MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRP-------PG-DKGSESRIRRPMNAF
:: :: : : :: : ..:.::::::
NP_008 MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKTPSGHIKRPMNAF
10 20 30 40
60 70 80 90 100 110
pF1KB8 MVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNY
:::.. ::... : ::.::::.:: ::. :. : :.: :.: :::::::.:: :::.:
NP_008 MVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDY
50 60 70 80 90 100
120 130 140 150
pF1KB8 KYRPRRKKQAKRLCKRVDP--GFLLSSLSRDQNALPEKRSGSR---GALG--------EK
:::::.:... : : : .: . :: :.: : : :: .
NP_008 KYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLP-GRGGRRAAGGPLGGGAAAPEDDD
110 120 130 140 150 160
160 170 180 190 200
pF1KB8 EDRGEY--------SPGTAL----PSLRGCYHE-----GPAGGGGGGTPSSVDTYPYGL-
:: : .:: : :. :. . ::.: :.... .. :
NP_008 EDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSGEGAAAAAAASPTPSEDEE
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB8 PTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLA
: : . : :. .: .: : :.: :: :. : :: :
NP_008 PEEEEEEAAAAEEGEEETVASG-EESLGFLSRLP--PG--------PAGLDCS-ALDRDP
230 240 250 260 270
270 280 290 300 310 320
pF1KB8 LGQSP-GVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEHPGFDALDQLSQ
: : :.: . : : . . . ..:
NP_008 DLQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY
280 290 300 310
330 340 350 360 370 380
pF1KB8 VELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLADATAT
>>NP_003099 (OMIM: 600898,615866) transcription factor S (441 aa)
initn: 483 init1: 377 opt: 400 Z-score: 260.3 bits: 57.1 E(85289): 9.2e-08
Smith-Waterman score: 417; 30.9% identity (49.9% similar) in 391 aa overlap (18-360:18-395)
10 20 30 40 50
pF1KB8 MASLLGAYPWPEGLECPALDAELSD--GQSPPAVPRPPGD--KGSESRIRRPMNAFMVWA
:::.: .. . :: :. . : : . ..:.:::::::::.
NP_003 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 KDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRP
: ::... :.::.::::.:: ::: :: : :.: :.. :::::::.:: :::.:::::
NP_003 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 RRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRG--ALGEKEDRGEYSPGTAL--P
:.: ..::. :. . ... .:: : : : : ..: . : :
NP_003 RKKP-------KMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAP
130 140 150 160 170
180 190 200
pF1KB8 SLRGCY-------HEGPAGG---------------GGGGTPSSV-----DTYPYGLPTPP
. : . : :: ::::. ..: :
NP_003 AAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDD
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 EMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQS
:.. ::.. : :. : . : . :. .:. : :.: : .:
NP_003 ELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPA----SPTLSSSA--ES
240 250 260 270 280
270 280 290 300 310 320
pF1KB8 P-GVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEHPGFDALDQLSQVELL
: :.:... : . : : . :. ... . : :. : :. . . :.
NP_003 PEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSS
290 300 310 320 330 340
330 340 350 360 370
pF1KB8 G--------DMDRNEFDQYLNTPGHPDSAT----GAMALSGHVPVSQVTPTGPTETSLIS
: : : :: :: ::. :. : .:.. .: :
NP_003 GSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSL
350 360 370 380 390 400
380
pF1KB8 VLADATATYYNSYSVS
NP_003 GSHFEFPDYCTPELSEMIAGDWLEANFSDLVFTY
410 420 430 440
388 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:52:01 2016 done: Fri Nov 4 16:52:02 2016
Total Scan time: 9.660 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]