Result of FASTA (omim) for
pF1KB8982
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8982, 378 aa
1>>>pF1KB8982 378 - 378 aa - 378 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7165+/-0.000308; mu= -2.2864+/- 0.019
mean_var=234.2958+/-47.588, 0's: 0 Z-trim(124.1): 134 B-trim: 0 in 0/62
Lambda= 0.083790
statistics sampled from 44989 (45123) to 44989 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.529), width: 16
Scan time: 10.160
The best scores are: opt bits E(85289)
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 2660 333.7 4.2e-91
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 1386 179.6 7.6e-45
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 818 111.1 4.9e-24
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 560 80.0 1.5e-14
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 552 78.9 2e-14
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 523 75.4 2.4e-13
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 519 75.0 4.3e-13
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 505 73.2 9.9e-13
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 500 72.6 1.5e-12
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 492 71.7 4e-12
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 489 71.3 4.2e-12
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 489 71.4 5.2e-12
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 487 71.1 5.8e-12
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 487 71.1 5.9e-12
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 486 71.0 6.7e-12
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 480 70.3 1.1e-11
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 466 68.5 2.7e-11
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 466 68.5 3.1e-11
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 455 67.2 7.9e-11
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 454 67.1 8.6e-11
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 454 67.1 8.9e-11
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 454 67.1 9.5e-11
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 445 66.0 1.9e-10
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 433 64.7 6.8e-10
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 433 64.7 6.9e-10
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 433 64.7 6.9e-10
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 433 64.7 6.9e-10
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 433 64.7 6.9e-10
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 433 64.7 7e-10
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 425 63.6 1e-09
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 423 63.3 1.1e-09
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 427 63.9 1.2e-09
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 421 63.1 1.4e-09
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 420 63.0 1.4e-09
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 423 63.5 1.8e-09
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 420 63.1 1.9e-09
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 412 62.1 3.7e-09
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 412 62.1 3.8e-09
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 412 62.1 3.9e-09
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 344 53.9 1.2e-06
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 344 53.9 1.2e-06
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 344 53.9 1.2e-06
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 344 53.9 1.2e-06
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 335 52.8 2.6e-06
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 335 52.8 2.6e-06
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 328 51.9 3.6e-06
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 327 51.7 3.7e-06
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 327 51.7 3.7e-06
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 327 51.7 3.7e-06
XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 323 51.3 5.1e-06
>>NP_036320 (OMIM: 274600,600791,601093) forkhead box pr (378 aa)
initn: 2660 init1: 2660 opt: 2660 Z-score: 1756.6 bits: 333.7 E(85289): 4.2e-91
Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 378 aa overlap (1-378:1-378)
10 20 30 40 50 60
pF1KB8 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 DSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF
310 320 330 340 350 360
370
pF1KB8 YNSVNTSGVLYPREGTEV
::::::::::::::::::
NP_036 YNSVNTSGVLYPREGTEV
370
>>NP_658982 (OMIM: 274600,600791,601093) forkhead box pr (283 aa)
initn: 2000 init1: 1386 opt: 1386 Z-score: 926.1 bits: 179.6 E(85289): 7.6e-45
Smith-Waterman score: 1814; 74.9% identity (74.9% similar) in 378 aa overlap (1-378:1-283)
10 20 30 40 50 60
pF1KB8 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPV
:::::::::::
NP_658 FKKVPRDEDDP-------------------------------------------------
190
250 260 270 280 290 300
pF1KB8 DSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLV
::::::::::::::
NP_658 ----------------------------------------------AYVSGGSPTSHPLV
200
310 320 330 340 350 360
pF1KB8 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF
210 220 230 240 250 260
370
pF1KB8 YNSVNTSGVLYPREGTEV
::::::::::::::::::
NP_658 YNSVNTSGVLYPREGTEV
270 280
>>NP_001129121 (OMIM: 612351) forkhead box protein I3 [H (420 aa)
initn: 864 init1: 733 opt: 818 Z-score: 552.5 bits: 111.1 E(85289): 4.9e-24
Smith-Waterman score: 977; 44.8% identity (65.7% similar) in 397 aa overlap (40-378:28-420)
10 20 30 40 50 60
pF1KB8 SPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATP----NPYLWF
:.: : . : ..:.: : :::::.
NP_001 MALYCGDNFGVYSQPGLPPPAATAAAPGAPPAARAPY-GLADYAAPPAAAANPYLWL
10 20 30 40 50
70 80 90
pF1KB8 NGPTM-----------------TPPPYLPGPNASPFL--PQAYGV----QRPLL---PSV
::: . ::: :: :.::: : : :. :::. :..
NP_001 NGPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAA
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB8 SG-----LGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVA
. : ..:::: . :.:.:::.:::::::::::::::..::...::::.:::.::
NP_001 PASPAAPAGPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 DNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRR
:.::::..::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRR
180 190 200 210 220 230
220 230 240 250 260
pF1KB8 KRKRKSDVSS-STASLALEKTESSLPVD-------SPKTTEPQDILDGAS----PGGTTS
::::.:..:. ::.. . :.: .: .:. :. .: . : :: :
NP_001 KRKRRSEASNGSTVAAGTSKSEEGLSSGLGSGVGGKPEEESPSTLLRPSHSPEPPEGTKS
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 SPEKRPSPPPSGAPCLNSFLSSMTAYVSGGS-------PTSHPLVTPGLSPEPSDKTGQN
. . .: ...::::.:.::... ..: : :. : : . : . .
NP_001 TASSPGGPMLTSTPCLNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQLPSSGVFSPT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 SLTFNSFSPL--TNLSNHSGG--GDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVLY
:.. : . : .: ...: : ... .:.:.. . ::. : :: :.: .....:
NP_001 SISEASADTLQLSNSTSNSTGQRSSYYSPFPAS--TSGGQS-SPFSSPFHNFSMVNSLIY
360 370 380 390 400 410
pF1KB8 PREGTEV
::::.::
NP_001 PREGSEV
420
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 578 init1: 509 opt: 560 Z-score: 382.2 bits: 80.0 E(85289): 1.5e-14
Smith-Waterman score: 573; 39.2% identity (58.7% similar) in 288 aa overlap (76-328:40-317)
50 60 70 80 90 100
pF1KB8 RPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGS
.:.: : . :.. : : ::
NP_001 PNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAP-MSVYSHPAHAEQYP--------GGM
10 20 30 40 50 60
110 120 130 140 150 160
pF1KB8 DLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKA
.. : : . .:.::::: :::.:::..::::..::. :::.. : :::: .:
NP_001 ARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQ
70 80 90 100 110 120
170 180 190 200 210 220
pF1KB8 GWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR--KSD-V
:::::::::::::.:: :::::. ::::.::::::. .::.::.: :.:.: :.: :
NP_001 GWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAV
130 140 150 160 170 180
230 240 250 260
pF1KB8 SSSTASLALEKTESSLPVDSPKTTEPQDILDGASPG---------------GTTSSPEKR
... . :. : : .: . :.. :: .:: :: :: .
NP_001 KDKEEKDRLHLKEPPPPGRQPPPAPPEQA-DGNAPGPQPPPVRIQDIKTENGTCPSPPQP
190 200 210 220 230
270 280 290 300 310
pF1KB8 PSPPP---SGA----PCLNSFLSSMTAYVSGGSP-----TSHPLVTPGLS-----PEPSD
:: ::. : ..: :: .. ::.:: ...:: : . : ::
NP_001 LSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSA
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB8 KTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVL
..: :. . .:.:
NP_001 PPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSS
300 310 320 330 340 350
>>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa)
initn: 576 init1: 493 opt: 552 Z-score: 380.0 bits: 78.9 E(85289): 2e-14
Smith-Waterman score: 566; 38.0% identity (58.0% similar) in 324 aa overlap (74-364:7-312)
50 60 70 80 90 100
pF1KB8 PQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLG
: ::. :::.: :: .:: :: :.
NP_005 MSHLFDPRLPALAASPML-YLYGPERPGLP----LA
10 20 30
110 120 130 140 150 160
pF1KB8 GSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKS
. . : .. : . .::::: :::::::. ::..:.::. :::.. : ::::. .
NP_005 FAPAAALAASGRAETPQ--KPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDN
40 50 60 70 80
170 180 190 200 210
pF1KB8 KAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKR-------
. :::::::::::::::: ::::.. ::::.:::::: : ::.:::.::..
NP_005 RQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGP
90 100 110 120 130 140
220 230 240 250 260
pF1KB8 -----KRKSDVSSSTASLALEKTESSLPVDSPKTTE-------PQDILDGASPGGTTSSP
:: . . .. : .. :. ..: .. :. .::: :: . :
NP_005 GAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWP
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB8 -EKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGL--SPEPSDKTGQNSLTFNS
:. . : . .. : .: .: : :: :. ::. :::. .:
NP_005 GTASPNEDAGDAAQGAAAVAVGQAARTGDGPGS-PL-RPASRSSPKSSDKS-------KS
210 220 230 240 250 260
330 340 350 360 370
pF1KB8 FSPLTNLSNHSG----GGDW----ANPMPTNMLSYGGSVL---SQFSPHFYNSVNTSGVL
:: . :....: .:: :.: : . : :.:.: :.. : : :.
NP_005 FSIDSILAGKQGQKPPSGDELLGGAKPGPGGRL--GASLLAASSSLRPPFNASLMLDPHV
270 280 290 300 310
pF1KB8 YPREGTEV
NP_005 QGGFYQLGIPFLSYFPLQVPDTVLHFQ
320 330 340
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 479 init1: 458 opt: 523 Z-score: 360.5 bits: 75.4 E(85289): 2.4e-13
Smith-Waterman score: 523; 37.1% identity (56.5% similar) in 294 aa overlap (72-350:7-283)
50 60 70 80 90
pF1KB8 PSPQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQ-----AYGVQRPLL
::: : :.. . . : :. :
NP_004 MTAESGPPP--PQPEVLATVKEERGETAAGAGVPGE
10 20 30
100 110 120 130 140 150
pF1KB8 PSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADN
. : :: ... .. .::::: ::::::: ::..::::. ::.....
NP_004 ATGRGAGGR--------RRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITER
40 50 60 70 80
160 170 180 190 200 210
pF1KB8 FPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKR
:::: . :::::::::.::::: :.::. :::::::.:::: : ::..:.: :.:
NP_004 FPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSFLRRR
90 100 110 120 130 140
220 230 240 250 260 270
pF1KB8 KR--KSDVSSSTASLALEKTESSLPVDSPKTTEPQDILDGASPGGTTSSPEKRPS--PPP
:: .::.:. : . . .. . . .. :. :: :.. : . ::
NP_004 KRFKRSDLSTYPAYM---HDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPGAVYAGYAPP
150 160 170 180 190 200
280 290 300 310 320
pF1KB8 SGA---PCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPEPSDKTGQNSLTFNSF-SPLTNL
: : : : : : : .:: .: :.: :: : : .: : .: :.
NP_004 SLAAPPPVYYPAASPGPCRVFGLVPE-RPL-SPELGPAPSGPGG--SCAFASAGAPATTT
210 220 230 240 250
330 340 350 360 370
pF1KB8 SNHSGGGDWANPM-PTNMLS-YGGSVLSQFSPHFYNSVNTSGVLYPREGTEV
. . .: : : :. . . :.:
NP_004 GYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVE
260 270 280 290 300 310
>>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa)
initn: 521 init1: 492 opt: 519 Z-score: 356.1 bits: 75.0 E(85289): 4.3e-13
Smith-Waterman score: 545; 42.0% identity (63.6% similar) in 250 aa overlap (121-351:70-308)
100 110 120 130 140 150
pF1KB8 VQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIY
::.::::: :::.:::..::.:..::. ::
NP_005 VYSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIY
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 QYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNG
:.. : :::: ..: :::::::::::::.:: :::::. ::::.::::::. .::.::
NP_005 QFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENG
100 110 120 130 140 150
220 230 240 250
pF1KB8 NFRRKRKR--KSDVSSST---ASL-----ALEKTESSLP--VDSPKTTEPQDIL--DGAS
.: :.:.: :.:::. : : : : . : .:.:: .: . .. ..::
NP_005 SFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAAS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 PGGTTSSPEKRPSPPPS--GAPCLNSFLSSMTAYVSGGSPTSH---PLVTPGLSPEPSDK
:. . . . :: . :.: : :. .. .:. : : : ::.: :
NP_005 PALPVITKVETLSPESALQGSP--RSAASTPAGSPDGSLPEHHAAAPNGLPGFSVE----
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 TGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVLY
: .:. . : .:: :.: . .: : :...
NP_005 ---NIMTLRTSPPGGELS--PGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGG
280 290 300 310 320
pF1KB8 PREGTEV
NP_005 YQCSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHH
330 340 350 360 370 380
>>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa)
initn: 525 init1: 462 opt: 505 Z-score: 349.6 bits: 73.2 E(85289): 9.9e-13
Smith-Waterman score: 505; 36.8% identity (61.6% similar) in 250 aa overlap (110-356:6-248)
80 90 100 110 120 130
pF1KB8 NASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGA
:: :. ..::::: :::::::...
NP_004 MQQQPLPGPGAPTTEP-TKPPYSYIALIAMAIQSS
10 20 30
140 150 160 170 180 190
pF1KB8 PDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTL
: .: ::: ::.:. : :: ... :::::::::::::.:: :::::. ::::.::::
NP_004 PGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTL
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 DPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTEPQDI-LDGASPG
::.:. ::..:.: :.:.: . ... .. . :.. . : . :: . .:. :
NP_004 DPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRG-----PLRATSQDPGVPNATTG
100 110 120 130 140
260 270 280 290 300 310
pF1KB8 GTTSSPEKRPSPPP-SGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLS-PEPSDKTGQNS
: : . :.: : . .... .:: .. : : :. .: :.:.
NP_004 RQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDGRPRP-PMEPKEISTPKPACPGELPV
150 160 170 180 190 200
320 330 340 350 360 370
pF1KB8 LTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVLYPREGT
: .: : .. . .. : :: .:: ... :..
NP_004 ATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHL
210 220 230 240 250 260
pF1KB8 EV
NP_004 LASAAPSPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFF
270 280 290 300 310 320
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 455 init1: 455 opt: 500 Z-score: 346.5 bits: 72.6 E(85289): 1.5e-12
Smith-Waterman score: 500; 33.8% identity (55.5% similar) in 308 aa overlap (60-358:8-301)
30 40 50 60 70 80
pF1KB8 LYYENFFHPQGVPSPQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAY
.: :.: : :: ::.
NP_036 MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEP
10 20 30
90 100 110 120 130 140
pF1KB8 GVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVR--PPYSYSALIAMAIHGAPDKRLTLS
: : ...: : . : :.... : : ::::: ::::::. :: .::::.
NP_036 G--REPEEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB8 QIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMF
::..... : :: : :::::::::.::::: ::::. .::::::::::: ::
NP_036 AIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMF
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB8 DNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTEPQDILDGASPGGTTSSPEKR
:::.: :.::: . . . . : .: .: . : .:. . :
NP_036 DNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPY-APYAPAP-------GPALLVPPPSAG
160 170 180 190 200
270 280 290 300 310 320
pF1KB8 PSP-PPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPE---PSDKTGQNSLTFNSFS
:.: ::. ..:... . .. :.: ..: . : ... : . .
NP_036 PGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPD
210 220 230 240 250 260
330 340 350 360 370
pF1KB8 PLTNLSNHSGGGDWANPMPTN-MLSYGG--SVLSQFSPHFYNSVNTSGVLYPREGTEV
:. ... : : :.:.. .:. .: ..:. .::
NP_036 RLVLPATRPGPG----PLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL
270 280 290 300 310
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 463 init1: 463 opt: 492 Z-score: 338.7 bits: 71.7 E(85289): 4e-12
Smith-Waterman score: 494; 34.3% identity (57.3% similar) in 321 aa overlap (25-334:50-349)
10 20 30 40
pF1KB8 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHP----QGVPSP--QRPS
:::. : . : .: :.: :.:
NP_036 AEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPL
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB8 FEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLG
:: .: .: . .:.:. . : . . : :... :
NP_036 TLPKEAAGAGAGP----GGD-------VGAPEADGCKGGVGGEEGGASGGGPGAGSGSAG
80 90 100 110 120
110 120 130 140 150 160
pF1KB8 WLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQ
: ::. . .::.::::: :::.::: .:.:.:::: : ..... ::.: .. .::
NP_036 GLA-PSKPK-NSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 NSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTAS
::::::::::::: :.::. .:::::::::::. : :::::.: :.::: . .
NP_036 NSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFK--RHQQEH
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 LALEKTESSLPVDSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAY
: . ...: ..: .. .:. .: . : .:: . .. .:
NP_036 L---REQTALMMQS---FGAYSLAAAAGAAGPYGRPYGLHPAAAAGAYSHPAAAAAAAAA
250 260 270 280 290
290 300 310 320 330 340
pF1KB8 VSGGSPTSHPLVTPGLSPE----PSDKTGQNSLTFNS-FSPLTNLSNHSGGGDWANPMPT
.. : . : :.: : : :: . :... .:.: ..: .:. .: :
NP_036 AALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAGTA
300 310 320 330 340 350
350 360 370
pF1KB8 NMLSYGGSVLSQFSPHFYNSVNTSGVLYPREGTEV
NP_036 GAAGTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLR
360 370 380 390 400 410
378 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:50:09 2016 done: Fri Nov 4 16:50:10 2016
Total Scan time: 10.160 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]