Result of FASTA (omim) for
pF1KB8979
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8979, 374 aa
1>>>pF1KB8979 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1503+/-0.000523; mu= 18.0164+/- 0.032
mean_var=126.4943+/-34.053, 0's: 0 Z-trim(108.3): 632 B-trim: 918 in 1/47
Lambda= 0.114035
statistics sampled from 15632 (16391) to 15632 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.528), E-opt: 0.2 (0.192), width: 16
Scan time: 7.270
The best scores are: opt bits E(85289)
NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 2520 426.9 3.7e-119
NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 2380 403.8 3e-112
XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 746 135.1 2.7e-31
NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 746 135.1 2.7e-31
NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 693 126.4 1.1e-28
NP_001983 (OMIM: 187930) proteinase-activated rece ( 425) 671 122.8 1.5e-27
XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 625 115.4 3.2e-25
XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 625 115.4 3.2e-25
XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 618 114.0 5.6e-25
XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 618 114.0 5.6e-25
XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 618 114.0 5.6e-25
NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 618 114.0 5.6e-25
XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 618 114.0 5.6e-25
XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 618 114.0 5.6e-25
XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 618 114.0 5.6e-25
NP_001298242 (OMIM: 187930) proteinase-activated r ( 304) 568 105.6 1.5e-22
XP_005260196 (OMIM: 602779) PREDICTED: proteinase- ( 273) 565 105.1 2e-22
NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 539 100.9 4.4e-21
NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 539 100.9 4.4e-21
XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 539 101.0 4.7e-21
NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 539 101.0 4.7e-21
NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 539 101.0 4.7e-21
NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo ( 373) 522 98.2 3.3e-20
NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 515 97.0 7.2e-20
XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 515 97.0 7.2e-20
NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 515 97.0 7.2e-20
XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 515 97.0 7.2e-20
XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 515 97.0 7.2e-20
XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 515 97.0 7.2e-20
NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 500 94.5 3.8e-19
NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 500 94.5 3.8e-19
NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 500 94.5 3.8e-19
NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 500 94.5 3.8e-19
NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 500 94.5 3.8e-19
NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 500 94.5 3.8e-19
NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 500 94.5 3.8e-19
NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 500 94.5 3.8e-19
NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 496 93.9 6.3e-19
NP_076404 (OMIM: 606379) G-protein coupled recepto ( 358) 478 90.9 4.8e-18
NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 476 90.6 5.8e-18
NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 476 90.6 5.8e-18
NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 476 90.6 5.8e-18
NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 476 90.6 5.8e-18
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 470 89.6 1.2e-17
NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 470 89.6 1.2e-17
XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 470 89.6 1.2e-17
NP_001333125 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 469 89.4 1.3e-17
NP_001333123 (OMIM: 606922) 2-oxoglutarate recepto ( 337) 469 89.4 1.3e-17
XP_005254101 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 469 89.4 1.3e-17
XP_005254103 (OMIM: 606922) PREDICTED: 2-oxoglutar ( 337) 469 89.4 1.3e-17
>>NP_004092 (OMIM: 601919) proteinase-activated receptor (374 aa)
initn: 2520 init1: 2520 opt: 2520 Z-score: 2260.3 bits: 426.9 E(85289): 3.7e-119
Smith-Waterman score: 2520; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KB8 MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL
310 320 330 340 350 360
370
pF1KB8 MSKTRNHSTAYLTK
::::::::::::::
NP_004 MSKTRNHSTAYLTK
370
>>NP_001243495 (OMIM: 601919) proteinase-activated recep (352 aa)
initn: 2380 init1: 2380 opt: 2380 Z-score: 2136.1 bits: 403.8 E(85289): 3e-112
Smith-Waterman score: 2380; 100.0% identity (100.0% similar) in 352 aa overlap (23-374:1-352)
10 20 30 40 50 60
pF1KB8 MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT
::::::::::::::::::::::::::::::::::::::
NP_001 MENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWT
10 20 30
70 80 90 100 110 120
pF1KB8 GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQP
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFL
280 290 300 310 320 330
370
pF1KB8 MSKTRNHSTAYLTK
::::::::::::::
NP_001 MSKTRNHSTAYLTK
340 350
>>XP_016864712 (OMIM: 600933) PREDICTED: proteinase-acti (383 aa)
initn: 533 init1: 301 opt: 746 Z-score: 682.9 bits: 135.1 E(85289): 2.7e-31
Smith-Waterman score: 746; 38.4% identity (70.0% similar) in 307 aa overlap (80-372:47-345)
50 60 70 80 90 100
pF1KB8 EFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGV
: . . . ::..:.: ..: .: .:::::.
XP_016 RSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGL
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB8 PANAVTLWMLFFRTRSICTTVFY-TNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRA
:.:...::...:::.. .:.: .:::.::.: . .:.:::::..::::..::.:: .
XP_016 PSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNV
80 90 100 110 120 130
170 180 190 200 210 220
pF1KB8 TTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPF
.::::::::::...:.:..:: .::.:. . . : . :. .: ..: .:.
XP_016 LIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPL
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB8 FILKQEYYLVQPDITTCHDVHNTCESSSPFQLY------YFISLAFFGFLIPFVLIIYCY
...:: .. .::::::: : :: ::.:::. ::.: : :
XP_016 YVVKQTIFIPALNITTCHDVL-------PEQLLVGDMFNYFLSLAIGVFLFPAFLTASAY
200 210 220 230 240
290 300 310 320 330
pF1KB8 AAIIRTL--NAYDH----RWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGL
. .:: : .:.:. . .: . .:... :::.:::..:..:. .. . .
XP_016 VLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHV
250 260 270 280 290 300
340 350 360 370
pF1KB8 YFIYLIALCLGSLNSCLDPFLYFLMSKT-RNHSTAYLTK
: .:..::::..::::.:::.:...:. :.:. :
XP_016 YALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRK
310 320 330 340 350 360
XP_016 SSSYSSSSTTVKTSY
370 380
>>NP_005233 (OMIM: 600933) proteinase-activated receptor (397 aa)
initn: 533 init1: 301 opt: 746 Z-score: 682.7 bits: 135.1 E(85289): 2.7e-31
Smith-Waterman score: 746; 38.4% identity (70.0% similar) in 307 aa overlap (80-372:61-359)
50 60 70 80 90 100
pF1KB8 EFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGV
: . . . ::..:.: ..: .: .:::::.
NP_005 RSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGL
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB8 PANAVTLWMLFFRTRSICTTVFY-TNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRA
:.:...::...:::.. .:.: .:::.::.: . .:.:::::..::::..::.:: .
NP_005 PSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNV
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB8 TTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPF
.::::::::::...:.:..:: .::.:. . . : . :. .: ..: .:.
NP_005 LIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGISLAIWLLILLVTIPL
160 170 180 190 200
230 240 250 260 270 280
pF1KB8 FILKQEYYLVQPDITTCHDVHNTCESSSPFQLY------YFISLAFFGFLIPFVLIIYCY
...:: .. .::::::: : :: ::.:::. ::.: : :
NP_005 YVVKQTIFIPALNITTCHDVL-------PEQLLVGDMFNYFLSLAIGVFLFPAFLTASAY
210 220 230 240 250 260
290 300 310 320 330
pF1KB8 AAIIRTL--NAYDH----RWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGL
. .:: : .:.:. . .: . .:... :::.:::..:..:. .. . .
NP_005 VLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHV
270 280 290 300 310 320
340 350 360 370
pF1KB8 YFIYLIALCLGSLNSCLDPFLYFLMSKT-RNHSTAYLTK
: .:..::::..::::.:::.:...:. :.:. :
NP_005 YALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRK
330 340 350 360 370 380
NP_005 SSSYSSSSTTVKTSY
390
>>NP_003941 (OMIM: 602779) proteinase-activated receptor (385 aa)
initn: 676 init1: 467 opt: 693 Z-score: 635.7 bits: 126.4 E(85289): 1.1e-28
Smith-Waterman score: 693; 36.9% identity (69.6% similar) in 293 aa overlap (70-362:54-344)
40 50 60 70 80 90
pF1KB8 FRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPA
: ..: . :.. ... . : . . :.:.::
NP_003 SVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT-LELPDSSRALLLGWVPTRLVPA
30 40 50 60 70 80
100 110 120 130 140 150
pF1KB8 IYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNW
.: ::.:::.:::...::.: .. . .:.. ::: ::.:. ..:: .::::: :. :
NP_003 LYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRW
90 100 110 120 130 140
160 170 180 190 200 210
pF1KB8 VFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWA
:::. :: .:. .::.:: :.:::: .:..::::.:::. :.: . :: : .:
NP_003 PFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWL
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB8 TVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLII
. ::. . .: . :.. : . :::. ..: .: : ::..: ..:.. ..
NP_003 MAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQ-PAFTCLALLGCFLPLLAML
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB8 YCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFI
::.: ..:: : .:. .. . ..:. . :.:::..:..:... . .::
NP_003 LCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGA
270 280 290 300 310 320
340 350 360 370
pF1KB8 YLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
:. .: :..::::.:::.:. .:
NP_003 YVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHS
330 340 350 360 370 380
>>NP_001983 (OMIM: 187930) proteinase-activated receptor (425 aa)
initn: 663 init1: 334 opt: 671 Z-score: 615.7 bits: 122.8 E(85289): 1.5e-27
Smith-Waterman score: 671; 32.1% identity (64.7% similar) in 377 aa overlap (2-362:4-375)
10 20 30 40 50
pF1KB8 MKALIFAAAGLLLLLPTFC-QSGMENDTNNLAKPTLPIKTFRGAPPNS-FEEFPFSAL
. :...:: . : : . .. . .. .. :: ..: ::. .: : .
NP_001 MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 EGWTGAT----ITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPAN
.. .: : .... . : .. ... . :::::: : ..:..: ::::..: :
NP_001 KNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 --AVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATT
:.....: ..... ..:.. .:: :: :: .:::::.:...:..: :: ::: .:
NP_001 IMAIVVFILKMKVKKP-AVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVT
130 140 150 160 170
180 190 200 210 220
pF1KB8 VIFYGNMYCSILLLACISINRYLAIVHP---FTYRGLPKHTYALVTCGLVWATVFLYMLP
. :: ::: ::::.. :::.:.::.:.: ...: : . .. :: .:: .. ..:
NP_001 AAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASF---TCLAIWALAIAGVVP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 FFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIR
... .: . .::::::: : . . ::: ... :..:... ::..:::
NP_001 LLLKEQTIQVPGLNITTCHDVLNETLLEG-YYAYYFSAFSAVFFFVPLIISTVCYVSIIR
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 TLN----AYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNT-DGLYFIYLI
:. : . . : .. :: :::.:.:..:: :.. ...: .. :: ::.
NP_001 CLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLL
300 310 320 330 340 350
350 360 370
pF1KB8 ALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
.:..:.. :.::..:. :
NP_001 CVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNL
360 370 380 390 400 410
>>XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinocepto (548 aa)
initn: 616 init1: 325 opt: 625 Z-score: 573.7 bits: 115.4 E(85289): 3.2e-25
Smith-Waterman score: 633; 32.0% identity (61.9% similar) in 378 aa overlap (12-363:116-487)
10 20 30
pF1KB8 MKALIFAAAGLLLLLPTFCQ---SGMENDTNNLAKPTLPIK
::::: . . :... ..: .: :
XP_006 GGWPPESRALRHGRRLKRCILLPGDPLSSHLLLLPLLLHRQFSAQKFLDSHLCRPDTA-K
90 100 110 120 130 140
40 50 60 70 80
pF1KB8 TFRGAPPNSFEEFPFSALEGWTGATITVKIKC---------PEESASHLHVKN------A
. : : .: .:: : . : .. . : : :. :...: : :
XP_006 NNRCA---DFLKFPSCPLSPGGAQTASLCLLCQGSWHQLESPGEDPSRMQVPNSTGPDNA
150 160 170 180 190 200
90 100 110 120 130 140
pF1KB8 TMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRT--RSICTTVFYTNLAIADFL
:. .: . . .:..: :: .:..:.: .::.: : :: ...:. ::...:..
XP_006 TLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSP-SVIFMINLSVTDLM
210 220 230 240 250 260
150 160 170 180 190 200
pF1KB8 FCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTY
. .:::.: :: : ..:::: .:: ..:: ::.::: ::: ..:::..:.:....:..
XP_006 LASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSS
270 280 290 300 310 320
210 220 230 240 250 260
pF1KB8 RGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHN-TCESSSPFQL
. .. ::...:. .: .. . :. : . : :: :: . : : .
XP_006 KRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWA
330 340 350 360 370 380
270 280 290 300 310
pF1KB8 YYFISLAFFGFLIPFVLIIYCYAAII----RTLNAYDHRWLWY-VKASLLILVIFTICFA
..... .. ::::::. . ::.: : :: .:. .. : . ..:. :. :::
XP_006 VFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFA
390 400 410 420 430 440
320 330 340 350 360 370
pF1KB8 PSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
:.:..:. : .. . . . : .: ..:::. ::.:::::.:.. :.
XP_006 PNNFVLLAHIVSRLFYGKS-YYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGC
450 460 470 480 490
XP_006 RRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQESVF
500 510 520 530 540
>>XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinocepto (548 aa)
initn: 616 init1: 325 opt: 625 Z-score: 573.7 bits: 115.4 E(85289): 3.2e-25
Smith-Waterman score: 633; 32.0% identity (61.9% similar) in 378 aa overlap (12-363:116-487)
10 20 30
pF1KB8 MKALIFAAAGLLLLLPTFCQ---SGMENDTNNLAKPTLPIK
::::: . . :... ..: .: :
XP_006 GGWPPESRALRHGRRLKRCILLPGDPLSSHLLLLPLLLHRQFSAQKFLDSHLCRPDTA-K
90 100 110 120 130 140
40 50 60 70 80
pF1KB8 TFRGAPPNSFEEFPFSALEGWTGATITVKIKC---------PEESASHLHVKN------A
. : : .: .:: : . : .. . : : :. :...: : :
XP_006 NNRCA---DFLKFPSCPLSPGGAQTASLCLLCQGSWHQLESPGEDPSRMQVPNSTGPDNA
150 160 170 180 190 200
90 100 110 120 130 140
pF1KB8 TMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRT--RSICTTVFYTNLAIADFL
:. .: . . .:..: :: .:..:.: .::.: : :: ...:. ::...:..
XP_006 TLQMLRNPAIAVALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSP-SVIFMINLSVTDLM
210 220 230 240 250 260
150 160 170 180 190 200
pF1KB8 FCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTY
. .:::.: :: : ..:::: .:: ..:: ::.::: ::: ..:::..:.:....:..
XP_006 LASVLPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSS
270 280 290 300 310 320
210 220 230 240 250 260
pF1KB8 RGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHN-TCESSSPFQL
. .. ::...:. .: .. . :. : . : :: :: . : : .
XP_006 KRWRRRRYAVAACAGTWLLLLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWA
330 340 350 360 370 380
270 280 290 300 310
pF1KB8 YYFISLAFFGFLIPFVLIIYCYAAII----RTLNAYDHRWLWY-VKASLLILVIFTICFA
..... .. ::::::. . ::.: : :: .:. .. : . ..:. :. :::
XP_006 VFLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFA
390 400 410 420 430 440
320 330 340 350 360 370
pF1KB8 PSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
:.:..:. : .. . . . : .: ..:::. ::.:::::.:.. :.
XP_006 PNNFVLLAHIVSRLFYGKS-YYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGC
450 460 470 480 490
XP_006 RRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRPGLQRQESVF
500 510 520 530 540
>>XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 616 init1: 325 opt: 618 Z-score: 569.4 bits: 114.0 E(85289): 5.6e-25
Smith-Waterman score: 618; 34.5% identity (66.9% similar) in 290 aa overlap (82-363:11-298)
60 70 80 90 100 110
pF1KB8 PFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPA
:::. .: . . .:..: :: .:..:.
XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPG
10 20 30 40
120 130 140 150 160
pF1KB8 NAVTLWMLFFRT--RSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRAT
: .::.: : :: ...:. ::...:... .:::.: :: : ..:::: .:: ..
XP_011 NLFSLWVLCRRMGPRSP-SVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVV
50 60 70 80 90
170 180 190 200 210 220
pF1KB8 TVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFF
:: ::.::: ::: ..:::..:.:....:.. . .. ::...:. .: .. . :.
XP_011 TVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ILKQEYYLVQPDITTCHDVHN-TCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAII--
: . : :: :: . : : . ..... .. ::::::. . ::.: :
XP_011 RTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILK
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 --RTLNAYDHRWLWY-VKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIA
:: .:. .. : . ..:. :. ::::.:..:. : .. . . . : .: ..
XP_011 LLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKS-YYHVYKLT
220 230 240 250 260 270
350 360 370
pF1KB8 LCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
:::. ::.:::::.:.. :.
XP_011 LCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAG
280 290 300 310 320 330
>>XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinocepto (359 aa)
initn: 616 init1: 325 opt: 618 Z-score: 569.4 bits: 114.0 E(85289): 5.6e-25
Smith-Waterman score: 618; 34.5% identity (66.9% similar) in 290 aa overlap (82-363:11-298)
60 70 80 90 100 110
pF1KB8 PFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPA
:::. .: . . .:..: :: .:..:.
XP_011 MQVPNSTGPDNATLQMLRNPAIAVALPVVYSLVAAVSIPG
10 20 30 40
120 130 140 150 160
pF1KB8 NAVTLWMLFFRT--RSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRAT
: .::.: : :: ...:. ::...:... .:::.: :: : ..:::: .:: ..
XP_011 NLFSLWVLCRRMGPRSP-SVIFMINLSVTDLMLASVLPFQIYYHCNRHHWVFGVLLCNVV
50 60 70 80 90
170 180 190 200 210 220
pF1KB8 TVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFF
:: ::.::: ::: ..:::..:.:....:.. . .. ::...:. .: .. . :.
XP_011 TVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGTWLLLLTALSPLA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ILKQEYYLVQPDITTCHDVHN-TCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAII--
: . : :: :: . : : . ..... .. ::::::. . ::.: :
XP_011 RTDLTYPVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFILLFLIPFVITVACYTATILK
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 --RTLNAYDHRWLWY-VKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIA
:: .:. .. : . ..:. :. ::::.:..:. : .. . . . : .: ..
XP_011 LLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRLFYGKS-YYHVYKLT
220 230 240 250 260 270
350 360 370
pF1KB8 LCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
:::. ::.:::::.:.. :.
XP_011 LCLSCLNNCLDPFVYYFASREFQLRLREYLGCRRVPRDTLDTRRESLFSARTTSVRSEAG
280 290 300 310 320 330
374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:48:58 2016 done: Fri Nov 4 16:48:59 2016
Total Scan time: 7.270 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]