Result of FASTA (omim) for
pF1KB8974
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8974, 369 aa
1>>>pF1KB8974 369 - 369 aa - 369 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9234+/-0.000562; mu= 18.4509+/- 0.035
mean_var=110.9643+/-29.427, 0's: 0 Z-trim(106.6): 654 B-trim: 771 in 1/51
Lambda= 0.121754
statistics sampled from 13912 (14694) to 13912 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.498), E-opt: 0.2 (0.172), width: 16
Scan time: 6.200
The best scores are: opt bits E(85289)
NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 2441 440.8 2.3e-123
XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 2441 440.8 2.3e-123
NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 2356 425.9 7e-119
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 2356 425.9 7e-119
NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 1007 189.0 1.5e-47
NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 1007 189.0 1.5e-47
NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 1007 189.0 1.5e-47
NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 1007 189.0 1.5e-47
NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 931 175.5 1.4e-43
NP_848540 (OMIM: 606065) atypical chemokine recept ( 350) 837 159.1 1.4e-38
NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 837 159.1 1.4e-38
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 837 159.1 1.5e-38
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 837 159.1 1.5e-38
NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 791 151.0 3.9e-36
NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 791 151.0 3.9e-36
NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 773 147.8 3.5e-35
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 773 147.8 3.6e-35
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 773 147.8 3.6e-35
NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 764 146.3 1.1e-34
XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 764 146.3 1.1e-34
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 757 145.0 2.5e-34
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 757 145.1 2.6e-34
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 757 145.1 2.7e-34
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 757 145.1 2.7e-34
NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 755 144.7 3.3e-34
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 748 143.4 7.4e-34
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 748 143.4 7.4e-34
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 748 143.4 7.4e-34
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 748 143.4 7.4e-34
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 746 143.1 9.5e-34
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 746 143.1 9.5e-34
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 746 143.1 9.5e-34
NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 746 143.1 9.5e-34
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 746 143.1 9.5e-34
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 746 143.1 9.5e-34
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 740 142.0 2e-33
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 737 141.5 2.8e-33
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 737 141.5 2.8e-33
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 722 138.9 1.8e-32
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 697 134.5 3.7e-31
NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 689 133.1 9.8e-31
NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 689 133.1 9.8e-31
NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 689 133.1 1e-30
NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 689 133.1 1e-30
NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 689 133.1 1e-30
NP_116743 (OMIM: 601613) C-X-C chemokine receptor ( 327) 687 132.7 1.2e-30
NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 687 132.8 1.3e-30
NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 677 131.0 4.3e-30
XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 677 131.0 4.4e-30
NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 677 131.1 4.6e-30
>>NP_112477 (OMIM: 604738) C-C chemokine receptor type 9 (369 aa)
initn: 2441 init1: 2441 opt: 2441 Z-score: 2335.8 bits: 440.8 E(85289): 2.3e-123
Smith-Waterman score: 2441; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
310 320 330 340 350 360
pF1KB8 ETTSGALSL
:::::::::
NP_112 ETTSGALSL
>>XP_011531614 (OMIM: 604738) PREDICTED: C-C chemokine r (369 aa)
initn: 2441 init1: 2441 opt: 2441 Z-score: 2335.8 bits: 440.8 E(85289): 2.3e-123
Smith-Waterman score: 2441; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
310 320 330 340 350 360
pF1KB8 ETTSGALSL
:::::::::
XP_011 ETTSGALSL
>>NP_001243298 (OMIM: 604738) C-C chemokine receptor typ (357 aa)
initn: 2356 init1: 2356 opt: 2356 Z-score: 2255.3 bits: 425.9 E(85289): 7e-119
Smith-Waterman score: 2356; 100.0% identity (100.0% similar) in 357 aa overlap (13-369:1-357)
10 20 30 40 50 60
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
10 20 30 40
70 80 90 100 110 120
pF1KB8 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
290 300 310 320 330 340
pF1KB8 ETTSGALSL
:::::::::
NP_001 ETTSGALSL
350
>>NP_006632 (OMIM: 604738) C-C chemokine receptor type 9 (357 aa)
initn: 2356 init1: 2356 opt: 2356 Z-score: 2255.3 bits: 425.9 E(85289): 7e-119
Smith-Waterman score: 2356; 100.0% identity (100.0% similar) in 357 aa overlap (13-369:1-357)
10 20 30 40 50 60
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
10 20 30 40
70 80 90 100 110 120
pF1KB8 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
290 300 310 320 330 340
pF1KB8 ETTSGALSL
:::::::::
NP_006 ETTSGALSL
350
>>NP_001288647 (OMIM: 600242) C-C chemokine receptor typ (372 aa)
initn: 1007 init1: 603 opt: 1007 Z-score: 974.5 bits: 189.0 E(85289): 1.5e-47
Smith-Waterman score: 1007; 41.9% identity (74.6% similar) in 358 aa overlap (13-364:22-371)
10 20 30 40 50
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFL
..::: ...:. :.... . : :..::.: . ::
NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT-----VDYTLFESLCSKKDVRNFKAWFL
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 PPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQ
: .: .. .:: :::.::.:.: : :.::::: .:::::.::.:::.:::::: .:: .
NP_001 PIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 WKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFT
: : . .::.. ..:::.:.: .::..:::.:::.::.::. :: : . :: ::. :
NP_001 WVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVG
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 IWVLAAALCIPEILYSQIKEESGIAI--CTMVYPSDESTKLKSAVLTLKVILGFFLPFVV
::.::..: :::.:::.... :. :... : .. .. . ....::..:...
NP_001 IWILATVLSIPELLYSDLQRSSSEQAMRCSLI---TEHVEAFITIQVAQMVIGFLVPLLA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 MACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNC
:. :: .::.::.::.. ..::.:: :.:..::.. :.::: ..:.::. . . :.:
NP_001 MSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 AVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQ---WVSF
.: ...: ..:: ..: . :.:: ::.:.: .:: :: : .:.:::.:: : : :
NP_001 ELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSC
300 310 320 330 340 350
350 360
pF1KB8 TR-REGSLKLSSMLLETTSGALSL
. :..:... . : :
NP_001 RHIRRSSMSVEAETTTTFSP
360 370
>>NP_001288646 (OMIM: 600242) C-C chemokine receptor typ (372 aa)
initn: 1007 init1: 603 opt: 1007 Z-score: 974.5 bits: 189.0 E(85289): 1.5e-47
Smith-Waterman score: 1007; 41.9% identity (74.6% similar) in 358 aa overlap (13-364:22-371)
10 20 30 40 50
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFL
..::: ...:. :.... . : :..::.: . ::
NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT-----VDYTLFESLCSKKDVRNFKAWFL
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 PPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQ
: .: .. .:: :::.::.:.: : :.::::: .:::::.::.:::.:::::: .:: .
NP_001 PIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 WKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFT
: : . .::.. ..:::.:.: .::..:::.:::.::.::. :: : . :: ::. :
NP_001 WVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVG
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 IWVLAAALCIPEILYSQIKEESGIAI--CTMVYPSDESTKLKSAVLTLKVILGFFLPFVV
::.::..: :::.:::.... :. :... : .. .. . ....::..:...
NP_001 IWILATVLSIPELLYSDLQRSSSEQAMRCSLI---TEHVEAFITIQVAQMVIGFLVPLLA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 MACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNC
:. :: .::.::.::.. ..::.:: :.:..::.. :.::: ..:.::. . . :.:
NP_001 MSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 AVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQ---WVSF
.: ...: ..:: ..: . :.:: ::.:.: .:: :: : .:.:::.:: : : :
NP_001 ELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSC
300 310 320 330 340 350
350 360
pF1KB8 TR-REGSLKLSSMLLETTSGALSL
. :..:... . : :
NP_001 RHIRRSSMSVEAETTTTFSP
360 370
>>NP_001288645 (OMIM: 600242) C-C chemokine receptor typ (372 aa)
initn: 1007 init1: 603 opt: 1007 Z-score: 974.5 bits: 189.0 E(85289): 1.5e-47
Smith-Waterman score: 1007; 41.9% identity (74.6% similar) in 358 aa overlap (13-364:22-371)
10 20 30 40 50
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFL
..::: ...:. :.... . : :..::.: . ::
NP_001 MKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT-----VDYTLFESLCSKKDVRNFKAWFL
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 PPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQ
: .: .. .:: :::.::.:.: : :.::::: .:::::.::.:::.:::::: .:: .
NP_001 PIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAKS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 WKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFT
: : . .::.. ..:::.:.: .::..:::.:::.::.::. :: : . :: ::. :
NP_001 WVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVG
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 IWVLAAALCIPEILYSQIKEESGIAI--CTMVYPSDESTKLKSAVLTLKVILGFFLPFVV
::.::..: :::.:::.... :. :... : .. .. . ....::..:...
NP_001 IWILATVLSIPELLYSDLQRSSSEQAMRCSLI---TEHVEAFITIQVAQMVIGFLVPLLA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 MACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNC
:. :: .::.::.::.. ..::.:: :.:..::.. :.::: ..:.::. . . :.:
NP_001 MSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 AVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQ---WVSF
.: ...: ..:: ..: . :.:: ::.:.: .:: :: : .:.:::.:: : : :
NP_001 ELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSC
300 310 320 330 340 350
350 360
pF1KB8 TR-REGSLKLSSMLLETTSGALSL
. :..:... . : :
NP_001 RHIRRSSMSVEAETTTTFSP
360 370
>>NP_001829 (OMIM: 600242) C-C chemokine receptor type 7 (378 aa)
initn: 1007 init1: 603 opt: 1007 Z-score: 974.4 bits: 189.0 E(85289): 1.5e-47
Smith-Waterman score: 1007; 41.9% identity (74.6% similar) in 358 aa overlap (13-364:28-377)
10 20 30 40
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQ
..::: ...:. :.... . : :..::.
NP_001 MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTT-----VDYTLFESLCSKKDVRN
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 FASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWA
: . ::: .: .. .:: :::.::.:.: : :.::::: .:::::.::.:::.::::::
NP_001 FKAWFLPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 IAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYS
.:: .: : . .::.. ..:::.:.: .::..:::.:::.::.::. :: : . :: :
NP_001 YSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLIS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 KMVCFTIWVLAAALCIPEILYSQIKEESGIAI--CTMVYPSDESTKLKSAVLTLKVILGF
:. : ::.::..: :::.:::.... :. :... : .. .. . ....::
NP_001 KLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLI---TEHVEAFITIQVAQMVIGF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 FLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYA
..:...:. :: .::.::.::.. ..::.:: :.:..::.. :.::: ..:.::. .
NP_001 LVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFN
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 MFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQ-
. :.: .: ...: ..:: ..: . :.:: ::.:.: .:: :: : .:.:::.:: :
NP_001 ITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQL
300 310 320 330 340 350
350 360
pF1KB8 --WVSFTR-REGSLKLSSMLLETTSGALSL
: : . :..:... . : :
NP_001 RQWSSCRHIRRSSMSVEAETTTTFSP
360 370
>>NP_001288643 (OMIM: 600242) C-C chemokine receptor typ (315 aa)
initn: 942 init1: 538 opt: 931 Z-score: 903.1 bits: 175.5 E(85289): 1.4e-43
Smith-Waterman score: 931; 43.2% identity (75.4% similar) in 317 aa overlap (54-364:1-314)
30 40 50 60 70 80
pF1KB8 SMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMT
.: .. .:: :::.::.:.: : :.::::
NP_001 MYSIICFVGLLGNGLVVLTYIYFKRLKTMT
10 20 30
90 100 110 120 130 140
pF1KB8 DMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVD
: .:::::.::.:::.:::::: .:: .: : . .::.. ..:::.:.: .::..:::.:
NP_001 DTYLLNLAVADILFLLTLPFWAYSAAKSWVFGVHFCKLIFAIYKMSFFSGMLLLLCISID
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB8 RYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAI--CTMV
::.::.::. :: : . :: ::. : ::.::..: :::.:::.... :. :...
NP_001 RYVAIVQAVSAHRHRARVLLISKLSCVGIWILATVLSIPELLYSDLQRSSSEQAMRCSLI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB8 YPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLT
: .. .. . ....::..:...:. :: .::.::.::.. ..::.:: :.:..
NP_001 ---TEHVEAFITIQVAQMVIGFLVPLLAMSFCYLVIIRTLLQARNFERNKAIKVIIAVVV
160 170 180 190 200
270 280 290 300 310 320
pF1KB8 VFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVG
::.. :.::: ..:.::. . . :.: .: ...: ..:: ..: . :.:: ::.:.:
NP_001 VFIVFQLPYNGVVLAQTVANFNITSSTCELSKQLNIAYDVTYSLACVRCCVNPFLYAFIG
210 220 230 240 250 260
330 340 350 360
pF1KB8 ERFRRDLVKTLKNLGCISQAQ---WVSFTR-REGSLKLSSMLLETTSGALSL
.:: :: : .:.:::.:: : : : . :..:... . : :
NP_001 VKFRNDLFKLFKDLGCLSQEQLRQWSSCRHIRRSSMSVEAETTTTFSP
270 280 290 300 310
>>NP_848540 (OMIM: 606065) atypical chemokine receptor 4 (350 aa)
initn: 808 init1: 380 opt: 837 Z-score: 813.4 bits: 159.1 E(85289): 1.4e-38
Smith-Waterman score: 837; 36.9% identity (69.8% similar) in 325 aa overlap (12-336:6-322)
10 20 30 40 50 60
pF1KB8 MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFI
:.. :: : . :. ... .. : :..::.::. ::: . .::.
NP_848 MALEQNQSTDYYYEE-NEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFV
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 VGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCK
.: :::.:. .: : . .: ::...::::.::::.: ::::::. :. : . .:::
NP_848 IGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 VVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALC
.....: .:: : . .. :::.:::.:... . ... : ..:: .:. : :
NP_848 ITSALYTLNFVSGMQFLACISIDRYVAVTK-VPSQSGVGKPCW---IICFCVWMAAILLS
120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHT
::.... .... : : ..: .:..:. . :.. .:: .::..:. :: : .:
NP_848 IPQLVFYTVNDN---ARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITART
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 LIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ
:.. . . . ::: .::. ::...:.::: . . ..:: .:..: .: .:: .:
NP_848 LMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLL
::..::.:::::::.::::.: :. ..:. :. :
NP_848 VTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTS
290 300 310 320 330 340
pF1KB8 ETTSGALSL
NP_848 TFSI
350
369 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:46:33 2016 done: Fri Nov 4 16:46:34 2016
Total Scan time: 6.200 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]