Result of FASTA (omim) for
pF1KB8965
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8965, 354 aa
1>>>pF1KB8965 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1878+/-0.000334; mu= 3.2903+/- 0.021
mean_var=170.0715+/-35.612, 0's: 0 Z-trim(120.8): 135 B-trim: 1384 in 1/52
Lambda= 0.098346
statistics sampled from 36329 (36482) to 36329 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.428), width: 16
Scan time: 8.250
The best scores are: opt bits E(85289)
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 2487 364.6 2e-100
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 949 146.4 1.1e-34
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 554 90.4 8.7e-18
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 526 86.4 1.4e-16
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 513 84.5 3.8e-16
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 511 84.3 6.8e-16
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 492 81.5 2.8e-15
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 490 81.2 3.9e-15
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 487 80.8 4.8e-15
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 485 80.6 6.8e-15
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 483 80.3 8.4e-15
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 482 80.2 1.1e-14
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 481 80.0 1.2e-14
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 479 79.7 1.3e-14
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 478 79.6 1.4e-14
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 477 79.4 1.6e-14
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 471 78.6 2.6e-14
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 454 76.2 1.5e-13
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 452 75.9 1.9e-13
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 452 75.9 2e-13
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 448 75.4 3e-13
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 441 74.3 4.6e-13
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 436 73.6 9.4e-13
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 436 73.6 9.5e-13
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 423 71.7 2.9e-12
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 398 68.3 4.7e-11
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 398 68.3 4.8e-11
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 398 68.3 4.9e-11
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 398 68.4 5.3e-11
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 377 65.3 3.7e-10
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 377 65.4 4.5e-10
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 371 64.5 7e-10
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 371 64.5 7.2e-10
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 371 64.5 7.2e-10
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 371 64.5 7.2e-10
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 371 64.5 7.2e-10
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 371 64.5 7.2e-10
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 361 62.9 1.2e-09
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 339 59.9 1.2e-08
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 338 59.7 1.4e-08
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 338 59.7 1.4e-08
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 338 59.7 1.4e-08
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 338 59.7 1.4e-08
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 338 59.8 1.9e-08
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 338 59.8 1.9e-08
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 338 59.8 1.9e-08
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 338 59.8 1.9e-08
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 338 59.8 1.9e-08
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 338 59.8 1.9e-08
NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 320 57.2 8.6e-08
>>NP_001442 (OMIM: 265380,601089) forkhead box protein F (379 aa)
initn: 2487 init1: 2487 opt: 2487 Z-score: 1923.9 bits: 364.6 E(85289): 2e-100
Smith-Waterman score: 2487; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:26-379)
10 20 30
pF1KB8 MDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMA
:::::::::::::::::::::::::::::::::::
NP_001 MSSAPEKQQPPHGGGGGGGGGGGAAMDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 IQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 YWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGLS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB8 CPPNSLALEGGLGMMNGHLPGNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGEYPHHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPPNSLALEGGLGMMNGHLPGNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGEYPHHD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 SSVPASPLLPTGAGGVMEPHAVYSGSAAAWPPSASAALNSGASYIKQQPLSPCNPAANPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVPASPLLPTGAGGVMEPHAVYSGSAAAWPPSASAALNSGASYIKQQPLSPCNPAANPL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB8 SGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHSAG
310 320 330 340 350 360
340 350
pF1KB8 GGSYYHQQVTYQDIKPCVM
:::::::::::::::::::
NP_001 GGSYYHQQVTYQDIKPCVM
370
>>NP_001443 (OMIM: 603250) forkhead box protein F2 [Homo (444 aa)
initn: 1164 init1: 819 opt: 949 Z-score: 743.5 bits: 146.4 E(85289): 1.1e-34
Smith-Waterman score: 1270; 56.5% identity (74.9% similar) in 386 aa overlap (4-354:81-444)
10 20 30
pF1KB8 MDPASSGPSKAKKTNAGIRRPEKPPYSYIALIV
:..: . :::...:.:::::::::::::::
NP_001 SSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB8 MAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGK
:::::::.:::::::::::::.:::::::.::::::::::::::::::::::::::::::
NP_001 MAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGK
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB8 GHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYS-MMNGLGFNH--LPDTYGFQGS
::::::::::::::::::::::::::::::::::::: ...::::. ::. . ::.
NP_001 GHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGASLLPQGFDFQAP
180 190 200 210 220 230
160 170 180 190
pF1KB8 AGG-LSCPPNSLALEGGLGMMNGHLPGNVD-GMALPSHS---------VPHLPSNGGHSY
.. :.: .: . ::: :: :.. : : . :::. :::. : : .:
NP_001 PSAPLGC--HSQGGYGGLDMM----PAGYDAGAGAPSHAHPHHHHHHHVPHMSPNPGSTY
240 250 260 270 280
200 210 220 230 240
pF1KB8 MGGC------------GGAAAGEY-PHHDSS-VPASPLLPTGAGGVMEPHAVYSGSAAAW
:..: ::...:.: : .:: ::.:: . .. .: :. :.. :: :
NP_001 MASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPVPSSPAMASA----IECHSPYTSPAAHW
290 300 310 320 330 340
250 260 270 280 290 300
pF1KB8 P-PSASAALNSGASYIKQQP-LSPC-NPAANP-LSGSLSTHSLEQPYLHQNSHNAPAELQ
:.:: :.:: : :.: ::::. : .:.:..:::: :::::... .:.
NP_001 SSPGASP-------YLKQPPALTPSSNPAASAGLHSSMSSYSLEQSYLHQNARE---DLS
350 360 370 380 390
310 320 330 340 350
pF1KB8 -GIPRYHSQSPSMCDRKEFVFSFNAMASSSMHSAGGGSYYHQ--QVTYQDIKPCVM
:.:::. .: .::::.::..::.. ::.: ...:::::. : . ::::::::
NP_001 VGLPRYQHHSTPVCDRKDFVLNFNGI--SSFHPSASGSYYHHHHQSVCQDIKPCVM
400 410 420 430 440
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 525 init1: 461 opt: 554 Z-score: 440.3 bits: 90.4 E(85289): 8.7e-18
Smith-Waterman score: 557; 33.0% identity (58.0% similar) in 367 aa overlap (7-350:108-456)
10 20 30
pF1KB8 MDPASSGPSKAKKTNAGIRRPE-KPPYSYIALIVMA
: . . ....: . : ::::::::::.::
NP_004 LLAPPAGGSPAPPGPAPAAGAGAGGGGGGGGAGGGGSAGSGAKNPLVKPPYSYIALITMA
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB8 IQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGH
: .:: :::::::: .:...:::..: .. .:.::.:::::::.::.:.:. : ::::.
NP_004 ILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGN
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB8 YWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGLS
:::.:: : ::..::: :: . :.:. : : . ..: . : :.::: .
NP_004 YWTLDPESADMFDNGSFLRRRKRFKRQ-PLLPPNAAAAESLLLR------G-AGAAGGAG
200 210 220 230 240
160 170 180 190 200 210
pF1KB8 CPPNSLALEGGLG----MMNGHLP-GNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGE
: . :: :. : : :. :: :. : .. . .. ..:::.
NP_004 DPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLP----PYAPPSALFA-AAAAAAAAAAF
250 260 270 280 290 300
220 230 240 250 260
pF1KB8 YPHHDSSVPASPLLPTGAGGVM-------EPHAVYSGSAAAWPPSASAALNSGASYIKQQ
.:: : : : ::.. . .:: . .. . : ::. : . ::: . ..
NP_004 HPHS----PPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASAAKAGGPGASALARS
310 320 330 340 350 360
270 280 290 300 310
pF1KB8 PLSPCNPAANPLSGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQS----------PSM
:.: . .. :. . .. . : .. .:. . . : :.. :.
NP_004 PFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAPGSSGGGCAAQAAVGPAA
370 380 390 400 410 420
320 330 340 350
pF1KB8 CDRKEFVFSFNAMASSSMHSAGGGSYYHQQVTYQDIKPCVM
. .: . : ::: ::. :. :: .. ....
NP_004 ALTRSLVAAAAAAASSVSSSAALGTL-HQGTALSSVENFTARISNC
430 440 450 460
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 528 init1: 461 opt: 526 Z-score: 418.5 bits: 86.4 E(85289): 1.4e-16
Smith-Waterman score: 526; 38.9% identity (62.5% similar) in 301 aa overlap (5-286:107-389)
10 20 30
pF1KB8 MDPASSGPSKAKKTN-AGIRRPE-KPPYSYIALI
..::. . .. :. : : ::::::::::
NP_004 CSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRSPLVKPPYSYIALI
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB8 VMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPG
.::: .:: :::::::: .:...:::..: .. .:.::.:::::::.::.:.:. : ::
NP_004 TMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPG
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB8 KGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAG
::.:::.:: : ::..::: :: . :.: : : : . . : :. ..:.:.
NP_004 KGNYWTLDPESADMFDNGSFLRRRKRFKR--QPLPPPHPHPHP----H-PELL-LRGGAA
200 210 220 230 240
160 170 180 190 200 210
pF1KB8 GLSCPPNSLALEGGLGMMNGHLPGNVDGMALPSHSVPHL-PSNGGHSYMGGCGGAAAGEY
. . : :. :.. .... : :.:::....: :. : . . . :::.
NP_004 AAGDPG---AFLPGFAAYGAY--GYGYGLALPAYGAPPPGPAPHPHPHPHAFAFAAAAAA
250 260 270 280 290 300
220 230 240 250
pF1KB8 PHHDSSVP-----ASPLLP------TGAGGVMEPHAVYSGSA-----AAWPPSASAALNS
. ::: : : : .:::.. : : :::. :. : .: :.
NP_004 APCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAP-APASGSGPGPGPAGLPAFLGAELGC
310 320 330 340 350 360
260 270 280 290 300 310
pF1KB8 GASYIKQQPLSPCNPAANPLSGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCD
. .. . ::: :::. .: : : :.:
NP_004 AKAFYAAS-LSP--PAAGTAAG-LPTALLRQGLKTDAGGGAGGGGAGAGQRPSFSIDHIM
370 380 390 400 410
320 330 340 350
pF1KB8 RKEFVFSFNAMASSSMHSAGGGSYYHQQVTYQDIKPCVM
NP_004 GHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVAGHIRLSHPGDALLS
420 430 440 450 460 470
>>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa)
initn: 497 init1: 476 opt: 513 Z-score: 410.8 bits: 84.5 E(85289): 3.8e-16
Smith-Waterman score: 513; 34.2% identity (61.1% similar) in 319 aa overlap (3-304:29-328)
10 20 30
pF1KB8 MDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVM
: . .:. : ... . :.::::::::::.:
NP_005 MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAM
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 AIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKG
:::..: .:.::. ::::...::::.. . :::.::.:::::::.::.:.:. ::::::
NP_005 AIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 HYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGL
:::.:: :::.:..::: : . : : . . .. .. ::..:
NP_005 SYWTLDPRCLDMFENGNYRRRKR--KPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGG
130 140 150 160 170
160 170 180 190 200 210
pF1KB8 SCPPNS---LALEGGLGMMNGHLPGNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGEY
: : : : : ...: :. . :. . :. ..: . .:. ...:.:.
NP_005 SGPAISRLQAAPAGPSPLLDG--PSPPAPLHWPGTASPN--EDAGDAAQGA-AAVAVGQA
180 190 200 210 220 230
220 230 240 250 260
pF1KB8 PHHDSSVPASPLLPTGAGG--------VMEPHAVYSGSAAAWPPSASAALNSGASYIKQQ
. .. :.::: :.. .. . .. .:. . :::.. :. :: .
NP_005 ARTGDG-PGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLG-GA-----K
240 250 260 270 280
270 280 290 300 310
pF1KB8 PLSPCNPAANPLSGSL--STHSLEQPY---LHQNSHNAPAELQ-GIPRYHSQSPSMCDRK
: .:.. :..:: .. ::. :. : . : . : :::
NP_005 P----GPGGR-LGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTV
290 300 310 320 330 340
320 330 340 350
pF1KB8 EFVFSFNAMASSSMHSAGGGSYYHQQVTYQDIKPCVM
NP_005 LHFQ
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 555 init1: 484 opt: 511 Z-score: 406.3 bits: 84.3 E(85289): 6.8e-16
Smith-Waterman score: 529; 34.7% identity (57.8% similar) in 329 aa overlap (23-341:78-394)
10 20 30 40 50
pF1KB8 MDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQF
::::::::::.::::..: :..::. ::::
NP_001 SHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQF
50 60 70 80 90 100
60 70 80 90 100 110
pF1KB8 LQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSF
...::::.: . :::.::.::::::::::.:.:. .:::: :::.:: : :::.:::
NP_001 IMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSF
110 120 130 140 150 160
120 130 140 150 160 170
pF1KB8 RRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGLSCPPNSLALEGGLGMMNG
:: : :..: .:.: . : ... : : : . :: : . : :
NP_001 LRRRRRFKKK-DAVKDKEEK-DRLHLKE-PPPPGRQPPPA----PP-----EQADGNAPG
170 180 190 200 210
180 190 200 210 220
pF1KB8 HLPGNV--DGMALPSHSVPHLPSNGGHSYMGGCGGAAAG---EYPHHDSSVPASPLLPTG
: : . . . . : :. . . : :.::: : : .:: .: : :
NP_001 PQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPG
220 230 240 250 260 270
230 240 250 260 270 280
pF1KB8 AGGVMEPHAVYSGSAAAWPPSASAAL-NSGASYIKQQPLSPCNPAANPLSGSLSTHSLEQ
. .: .. ....: ::. :: . . .. .. .. . . .. ::. : .
NP_001 SLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLAS
280 290 300 310 320 330
290 300 310 320 330 340
pF1KB8 PYLHQNSHNAPAELQGI--PRYHSQSPSMCDRKEFVFSFNAMA--SSSMHSAGGGSYYHQ
. . :: : : : : :.. . : .. . ... .:::.. ::
NP_001 AAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHC
340 350 360 370 380 390
350
pF1KB8 QVTYQDIKPCVM
NP_001 NLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGG
400 410 420 430 440 450
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 476 init1: 436 opt: 492 Z-score: 395.2 bits: 81.5 E(85289): 2.8e-15
Smith-Waterman score: 492; 37.1% identity (57.7% similar) in 272 aa overlap (6-262:51-308)
10 20 30
pF1KB8 MDPASSGPSKAKKTNAGIRRPE---KPPYSYIALI
..:. : . ::: ::::::::::
NP_036 AVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALI
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB8 VMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPG
.::. .: .::::. ::.:. :: :.: : . :.::.::::.::.::.:.:. : ::
NP_036 AMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPG
90 100 110 120 130 140
100 110 120 130 140
pF1KB8 KGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQG---
::.:::.:::. ::..::: :: . :.: . . : : . : . . :
NP_036 KGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPA-PGPAL
150 160 170 180 190
150 160 170 180 190 200
pF1KB8 -----SAGGLSCPPNSLALEGGLGMMNGHLPGNVDGMALPSHSVPHLPSNGGHSYMGGCG
::: :: : .: .: : .. :.. : :. .. .. :.
NP_036 LVPPPSAGPGPSPPARLFSVDSL--VN--LQPELAGLGAPEPPCCAAPDAAAAAF-PPCA
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB8 GAAAGEYPHHDSSVPASPLLPT---GAGGV-MEPHAVYSGSAAAWPPSASAALNSGASYI
.::. : :.:: .::. : : . :: . .: ::: : :. : .:.
NP_036 AAAS---PPLYSQVPDRLVLPATRPGPGPLPAEPLLALAGPAAALGP-----LSPGEAYL
260 270 280 290 300
270 280 290 300 310 320
pF1KB8 KQQPLSPCNPAANPLSGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFV
.:
NP_036 RQPGFASGLERYL
310
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 525 init1: 463 opt: 490 Z-score: 392.7 bits: 81.2 E(85289): 3.9e-15
Smith-Waterman score: 511; 34.7% identity (59.3% similar) in 300 aa overlap (4-281:27-320)
10 20 30
pF1KB8 MDPASSG-PSKAKKTNAGIRRPE------KPPYSYIA
:..: :..: .:: :: . ::::::::
NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 LIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGR
::.::: .: .::::. ::.:. ::::.: . . :.::.::::.::.::.:.:. ::
NP_004 LIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGR
70 80 90 100 110 120
100 110 120 130 140
pF1KB8 PGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYG----
::::.::..:: .: ::: ::: :: . :.:. . : : : .. . . .
NP_004 PGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAY-MHDAAAAAAAAAAAAAAAA
130 140 150 160 170
150 160 170 180 190 200
pF1KB8 -FQGSAGGLSCPPNSLALEGGLGMMNGHLPGNVDGMAL---PSHSVPHLPSNGGHSYMGG
: :.. . . :: :. .: . . : : : : . .: .:
NP_004 IFPGAVPA-ARPPYPGAVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPLSPELGP
180 190 200 210 220 230
210 220 230 240 250
pF1KB8 CGGAAAGEYPHHDSSVPASPL--LPTGAGGV--MEPHA---VYSGSAAAWPPSASAALNS
.. .: ....::. :.: :. .: : .:.: .:.: .:..:. .
NP_004 APSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFA
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB8 GASYIKQQPLSPCNPAANPLSGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCD
.:. . .: .: :. ::.. :
NP_004 AAGRLA----GPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAY
300 310 320 330 340 350
>>NP_004109 (OMIM: 602939) forkhead box protein S1 [Homo (330 aa)
initn: 486 init1: 464 opt: 487 Z-score: 391.1 bits: 80.8 E(85289): 4.8e-15
Smith-Waterman score: 493; 35.7% identity (55.1% similar) in 305 aa overlap (16-309:11-297)
10 20 30 40 50 60
pF1KB8 MDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFF
: .: ::::::::::.::::::: .: ::: ::.....:: :.
NP_004 MQQQPLPGPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFY
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 RGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFR
: . ::.::.::::::::::.:.:. .:::: :::.:: . :::.::: :: : :
NP_004 RHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFT
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 RKCQALKPMYSMMNGLG-FNHLPDTYGFQGSAGGLSC--PPN-----SLALEGGLGMMNG
:. : : . . : ... : .: ::. .:.. : .: : .
NP_004 RQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSFPPELPDPKGLSFGGLVGAMPA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 HL-PGNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGEYPHHDSSVPASPLLPTGAGGV
. :...:: : : :.. .. : :: : :: . : . ::
NP_004 SMCPATTDGRPRP----PMEPKE-----ISTPKPACPGELPVATSS-SSCPAFGFPAG-F
180 190 200 210 220
240 250 260 270 280
pF1KB8 MEPHAVYSGSAAAWPPSASAALNSGASY-IKQQPLSPCNPAANPLSGSLSTHS-LEQPYL
: .. .. . . : .. :.:: . : :. : : : :.. . :
NP_004 SEAESFNKAPTPVLSPESGI----GSSYQCRLQALNFCMGADPGLEHLLASAAPSPAPPT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 HQNSHNAPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHSAGGGSYYHQQVTYQDI
.: :: : : :..
NP_004 PPGSLRAPLPL---PTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE
290 300 310 320 330
>>NP_150285 (OMIM: 612788) forkhead box protein Q1 [Homo (403 aa)
initn: 458 init1: 329 opt: 485 Z-score: 388.3 bits: 80.6 E(85289): 6.8e-15
Smith-Waterman score: 487; 35.4% identity (57.4% similar) in 277 aa overlap (6-277:103-364)
10 20 30
pF1KB8 MDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMA
.: ... ... ::: ::::::::::.::
NP_150 GAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRP-KPPYSYIALIAMA
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB8 IQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRP-GKG
:..: ::::.:: ..:...:::::::: ::.::::::::::.::.:. . .:: ::
NP_150 IRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKD
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB8 HYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGGL
.:: ..: ::. : .: :::: . . .. . : .. :. : .. .
NP_150 NYWMLNPNSEYTFADGVFRRRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAPAAPASPRM
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB8 SCPPNSLALEGGLGMMNGHLPGNVDG-MALPSHSVPHLPSNGGHSYMGGCGGAAAGEYPH
: . . : ... . .:. . : .: . : . . : .: :
NP_150 RSPARQEERASPAGKFSSSFA--IDSILRKPFRSRRLRDTAPGTTLQWG--AAPCPPLPA
260 270 280 290 300
220 230 240 250 260 270
pF1KB8 HDSSVPASP---LLPTGAGGVMEPHAVYSGSAAAWPPSASAALNSGASYIKQQPLSPCNP
. .::.: ::: : :. :: : .. : ::.: : . :: :
NP_150 FPALLPAAPCRALLPLCAYGAGEP-ARLGAREAEVPPTAPPLLLA--------PL-PAAA
310 320 330 340 350
280 290 300 310 320 330
pF1KB8 AANPLSGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSS
:.:: :
NP_150 PAKPLRGPAAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA
360 370 380 390 400
354 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:44:13 2016 done: Fri Nov 4 16:44:14 2016
Total Scan time: 8.250 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]