Result of FASTA (omim) for
pF1KB8964
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8964, 350 aa
1>>>pF1KB8964 350 - 350 aa - 350 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8205+/-0.000334; mu= -6.6883+/- 0.021
mean_var=310.9000+/-63.413, 0's: 0 Z-trim(125.4): 130 B-trim: 987 in 1/61
Lambda= 0.072738
statistics sampled from 49080 (49212) to 49080 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.832), E-opt: 0.2 (0.577), width: 16
Scan time: 9.200
The best scores are: opt bits E(85289)
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 2441 268.7 1.3e-71
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 773 93.8 7.8e-19
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 773 93.8 8.2e-19
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 770 93.5 1e-18
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 770 93.5 1e-18
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 641 79.9 1.2e-14
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 576 73.0 1e-12
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 545 69.9 1.5e-11
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 528 68.0 3.8e-11
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 523 67.6 6.6e-11
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 519 67.2 9.1e-11
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 515 66.7 1.1e-10
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 504 65.6 2.7e-10
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 501 65.2 2.9e-10
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 500 65.1 3.1e-10
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 500 65.1 3.3e-10
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 494 64.4 4e-10
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 495 64.6 4.7e-10
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 493 64.4 5.9e-10
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 486 63.6 8.7e-10
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 480 62.9 1.2e-09
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 468 61.7 3e-09
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 466 61.5 3.5e-09
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 433 58.1 4e-08
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 431 57.9 4.8e-08
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 411 55.9 2.9e-07
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 400 54.6 4.2e-07
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 402 54.9 5e-07
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 402 54.9 5.1e-07
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 402 54.9 5.2e-07
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 386 53.3 1.7e-06
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 386 53.3 1.7e-06
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 386 53.3 1.7e-06
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 386 53.3 1.7e-06
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 386 53.3 1.7e-06
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 386 53.3 1.7e-06
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 381 52.7 2.3e-06
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 381 52.8 2.8e-06
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 346 48.9 2.1e-05
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 342 48.4 2.3e-05
XP_011512595 (OMIM: 608924) PREDICTED: forkhead bo ( 581) 328 47.2 0.00011
XP_016865723 (OMIM: 608924) PREDICTED: forkhead bo ( 649) 328 47.2 0.00012
XP_011512594 (OMIM: 608924) PREDICTED: forkhead bo ( 655) 328 47.2 0.00012
NP_001012427 (OMIM: 608924) forkhead box protein P ( 678) 328 47.2 0.00013
XP_006715054 (OMIM: 608924) PREDICTED: forkhead bo ( 679) 328 47.2 0.00013
NP_001012426 (OMIM: 608924) forkhead box protein P ( 680) 328 47.2 0.00013
XP_011512592 (OMIM: 608924) PREDICTED: forkhead bo ( 685) 328 47.2 0.00013
XP_011512591 (OMIM: 608924) PREDICTED: forkhead bo ( 687) 328 47.2 0.00013
XP_016865722 (OMIM: 608924) PREDICTED: forkhead bo ( 687) 328 47.2 0.00013
XP_016880719 (OMIM: 600838,601705) PREDICTED: fork ( 485) 320 46.3 0.00017
>>NP_004488 (OMIM: 602295) hepatocyte nuclear factor 3-g (350 aa)
initn: 2441 init1: 2441 opt: 2441 Z-score: 1406.5 bits: 268.7 E(85289): 1.3e-71
Smith-Waterman score: 2441; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KB8 MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMTLNPLSSPYPPGGLPASPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMTLNPLSSPYPPGGLPASPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAAST
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TTPAATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDAPYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TTPAATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDAPYNF
250 260 270 280 290 300
310 320 330 340 350
pF1KB8 NHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSLLNAS
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSLLNAS
310 320 330 340 350
>>XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte nucl (439 aa)
initn: 900 init1: 754 opt: 773 Z-score: 459.1 bits: 93.8 E(85289): 7.8e-19
Smith-Waterman score: 836; 46.2% identity (62.0% similar) in 355 aa overlap (19-321:38-383)
10 20 30 40
pF1KB8 MLGSVKMEAHDLAEWSYYPEAGEVYSP--VTPVP--TMAPLNSYMT--
: : :: :. .: . . .::. .
XP_016 MNSMNTYMTMNTMTTSGNMTPASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 LNPLSSPYPPGGLPA-SPLPSGPLAPPAP-AAPLGPTFPGLGVSGGSSSSGYGAPGPGLV
.. ... :.:. : . .. . .: :: ..: . .. . :. : . : :
XP_016 VTAMGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYA--PSNLGRSRAGGG--
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 HGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQR
: : ..: ::::::::::::::::::::.::::::::::::::::::::.::::
XP_016 -GDA--KTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 WQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVK
:::::::::::::::::::::::::::::::.:::.:::::::::::::::::: :..
XP_016 WQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPG
190 200 210 220 230 240
230 240 250 260
pF1KB8 KGGSGAATTTRNGT-GSAASTTTPAATVTSPPQPPP---------------PAPEPEA--
::.:.. . .:. :. : :... ..: : ::: : :
XP_016 AGGGGGSGSGGSGAKGGPESRKDPSGA-SNPSADSPLHRGVHGKTGQLEGAPAPGPAASP
250 260 270 280 290
270 280 290
pF1KB8 QGGEDVGALDCG------SPASST--PYFTG----LELPG--------------ELKLDA
: . :: : .::::: : .: .:. .:: :
XP_016 QTLDHSGATATGGASELKTPASSTAPPISSGPGALASVPASHPAHGLAPHESQLHLKGDP
300 310 320 330 340 350
300 310 320 330 340 350
pF1KB8 PYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSLLNAS
:.:::::::::::: .. :::
XP_016 HYSFNHPFSINNLMS-SSEQQHKLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSPIE
360 370 380 390 400 410
>>NP_004487 (OMIM: 602294) hepatocyte nuclear factor 3-a (472 aa)
initn: 973 init1: 754 opt: 773 Z-score: 458.7 bits: 93.8 E(85289): 8.2e-19
Smith-Waterman score: 836; 46.2% identity (62.0% similar) in 355 aa overlap (19-321:71-416)
10 20 30 40
pF1KB8 MLGSVKMEAHDLAEWSYYPEAGEVYSP--VTPVP--TMAPLNSYMT--
: : :: :. .: . . .::. .
NP_004 MNSMNTYMTMNTMTTSGNMTPASFNMSYANPGLGAGLSPGAVAGMPGGSAGAMNSMTAAG
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB8 LNPLSSPYPPGGLPA-SPLPSGPLAPPAP-AAPLGPTFPGLGVSGGSSSSGYGAPGPGLV
.. ... :.:. : . .. . .: :: ..: . .. . :. : . : :
NP_004 VTAMGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYA--PSNLGRSRAGGG--
110 120 130 140 150
110 120 130 140 150 160
pF1KB8 HGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQR
: : ..: ::::::::::::::::::::.::::::::::::::::::::.::::
NP_004 -GDA--KTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQR
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB8 WQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVK
:::::::::::::::::::::::::::::::.:::.:::::::::::::::::: :..
NP_004 WQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPG
220 230 240 250 260 270
230 240 250 260
pF1KB8 KGGSGAATTTRNGT-GSAASTTTPAATVTSPPQPPP---------------PAPEPEA--
::.:.. . .:. :. : :... ..: : ::: : :
NP_004 AGGGGGSGSGGSGAKGGPESRKDPSGA-SNPSADSPLHRGVHGKTGQLEGAPAPGPAASP
280 290 300 310 320 330
270 280 290
pF1KB8 QGGEDVGALDCG------SPASST--PYFTG----LELPG--------------ELKLDA
: . :: : .::::: : .: .:. .:: :
NP_004 QTLDHSGATATGGASELKTPASSTAPPISSGPGALASVPASHPAHGLAPHESQLHLKGDP
340 350 360 370 380 390
300 310 320 330 340 350
pF1KB8 PYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSLLNAS
:.:::::::::::: .. :::
NP_004 HYSFNHPFSINNLMS-SSEQQHKLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSPIE
400 410 420 430 440 450
>>NP_710141 (OMIM: 600288) hepatocyte nuclear factor 3-b (457 aa)
initn: 997 init1: 720 opt: 770 Z-score: 457.2 bits: 93.5 E(85289): 1e-18
Smith-Waterman score: 864; 44.0% identity (62.1% similar) in 375 aa overlap (13-313:13-385)
10 20 30 40 50
pF1KB8 MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPT---MAPLNSYMTLNPLSSPYPPGGLPA
..:: : : :: :. . . : .:.::... . :.. :
NP_710 MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSGSGNMSA
10 20 30 40 50 60
60 70 80 90
pF1KB8 SPL-----------PS-GPLAPPAPA-------------APLGPTF-PGLGVSGGSSSSG
. . :: . ..: : : : .:: . :.:. ::.....
NP_710 GSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGA
70 80 90 100 110 120
100 110 120 130
pF1KB8 YGAPGP--------------GLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKM
.:. .: :: .... :: ::: .::::::::::::::::::.:.::
NP_710 MGGLAPYANMNSMSPMYGQAGLSRARD-PKTYRRSYTHAKPPYSYISLITMAIQQSPNKM
130 140 150 160 170
140 150 160 170 180 190
pF1KB8 LTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSS
:::::::::::::::.::.:::::::::::::::::::.:: ::::::::::.:.:::.:
NP_710 LTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDS
180 190 200 210 220 230
200 210 220 230 240
pF1KB8 GNMFENGCYLRRQKRFKLEEKV------------KKGGSGA-ATTTRNGTGSAASTTTPA
::::::::::::::::: :... ::...:: :. .. : ... .. :::
NP_710 GNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASETPA
240 250 260 270 280 290
250 260 270 280
pF1KB8 ATVTSPPQPPPPAPEPEAQG-----GEDVGALDCGSPASST-------------PYFTGL
.: :: . : : . : : ..::. :: : :. ::
NP_710 GT-ESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGL
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB8 ELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSL
..:: . : :::::::::::: .
NP_710 PPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPM
360 370 380 390 400 410
>>NP_068556 (OMIM: 600288) hepatocyte nuclear factor 3-b (463 aa)
initn: 997 init1: 720 opt: 770 Z-score: 457.1 bits: 93.5 E(85289): 1e-18
Smith-Waterman score: 864; 44.0% identity (62.1% similar) in 375 aa overlap (13-313:19-391)
10 20 30 40 50
pF1KB8 MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPT---MAPLNSYMTLNPLSSPYP
..:: : : :: :. . . : .:.::... .
NP_068 MHSASSMLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSG
10 20 30 40 50 60
60 70 80
pF1KB8 PGGLPASPL-----------PS-GPLAPPAPA-------------APLGPTF-PGLGVSG
:.. :. . :: . ..: : : : .:: . :.:. :
NP_068 SGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLG
70 80 90 100 110 120
90 100 110 120 130
pF1KB8 GSSSSGYGAPGP--------------GLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQ
:......:. .: :: .... :: ::: .:::::::::::::::::
NP_068 GQAAGAMGGLAPYANMNSMSPMYGQAGLSRARD-PKTYRRSYTHAKPPYSYISLITMAIQ
130 140 150 160 170
140 150 160 170 180 190
pF1KB8 QAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYW
:.:.:::::::::::::::::.::.:::::::::::::::::::.:: ::::::::::.:
NP_068 QSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFW
180 190 200 210 220 230
200 210 220 230
pF1KB8 ALHPSSGNMFENGCYLRRQKRFKLEEKV------------KKGGSGA-ATTTRNGTGSAA
.:::.:::::::::::::::::: :... ::...:: :. .. : ...
NP_068 TLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGP
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 STTTPAATVTSPPQPPPPAPEPEAQG-----GEDVGALDCGSPASST-------------
.. :::.: :: . : : . : : ..::. :: :
NP_068 ASETPAGT-ESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGP
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB8 PYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQG
:. :: ..:: . : :::::::::::: .
NP_068 PHHPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYP
360 370 380 390 400 410
350
pF1KB8 LYSRSLLNAS
NP_068 GYGSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
420 430 440 450 460
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 741 init1: 542 opt: 641 Z-score: 383.9 bits: 79.9 E(85289): 1.2e-14
Smith-Waterman score: 647; 43.4% identity (62.0% similar) in 274 aa overlap (65-334:79-331)
40 50 60 70 80 90
pF1KB8 APLNSYMTLNPLSSPYPPGGLPASPLPSGPLAPPA---PAAPLGPTFPGLGVSGGSSSSG
::::: :: : ::. :. :...:....:
NP_004 PAQRRRRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPP-GPA-PAAGAGAGGGGGG
50 60 70 80 90 100
100 110 120 130 140 150
pF1KB8 YGAPGPGLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLF
:: : : .: . ::. :::::::.:::::: :.: : :::::: ..: :
NP_004 GGAGGGG-----SAGSGAKNPLV--KPPYSYIALITMAILQSPKKRLTLSEICEFISGRF
110 120 130 140 150
160 170 180 190 200 210
pF1KB8 PYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQK
:::::. :::::::.::.::::::. : : .::::.::.: : :..::.:: .:::.:
NP_004 PYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRK
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB8 RFKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATVTS-PPQPPPPAPEPEAQGGEDVGA
::: . . ....: . :.:.:... :::... :: :::: :.: : :
NP_004 RFKRQPLLPPNAAAAESLLLRGAGAAGGAGDPAAAAALFPPAPPPP---PHAYG---YGP
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB8 LDCGSPASSTPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAE
:: . :: : . : :: : : ::. .. . :
NP_004 YGCGYGLQLPPYAPPSALFAAAAAAAAAAAFHPHS------PPPPPPPHGAAAELARTAF
280 290 300 310 320
340 350
pF1KB8 GGEPGVYYQGLYSRSLLNAS
: .:
NP_004 GYRPHPLGAALPGPLPASAAKAGGPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAAA
330 340 350 360 370 380
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 561 init1: 510 opt: 576 Z-score: 349.4 bits: 73.0 E(85289): 1e-12
Smith-Waterman score: 603; 37.3% identity (59.0% similar) in 300 aa overlap (46-316:7-293)
20 30 40 50 60 70
pF1KB8 SYYPEAGEVYSPVTPVPTMAPLNSYMTLNPLSSPYPPGGLPASPL--PSGPLAPPAPAAP
.. : .:.:: : :::: ::.: :
NP_036 MAGRSDMDPPAAFSGFPALPAVAPSGP--PPSPLAG
10 20 30
80 90 100 110 120 130
pF1KB8 LGP-TFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQ
: : ...: . .. ::::: . :::: ..:::::::.::.::. .
NP_036 AEPGREPEEAAAGRGEAAPTPAPGPG--------RRRRRPLQRGKPPYSYIALIAMALAH
40 50 60 70 80
140 150 160 170 180 190
pF1KB8 APGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWA
:::. :::. ::..: . : .::.. ..:::::::.:..::::::: : : .::::.::.
NP_036 APGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWT
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB8 LHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATVTSP--
: :....::.:: .:::.:::: : ..... . . : . :: : :
NP_036 LDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSA
150 160 170 180 190 200
260 270 280
pF1KB8 -PQPPPPA--------------------PEPEAQGGEDVGAL---DCGSPASSTPYFTGL
: : ::: ::: .. :..: :.. :.: : ..
NP_036 GPGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFPPCAA-AASPPLYS--
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB8 ELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSRSL
..: .: : : :. . :.. ::
NP_036 QVPDRLVLPATRPGPGPLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL
270 280 290 300 310
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 623 init1: 510 opt: 545 Z-score: 328.4 bits: 69.9 E(85289): 1.5e-11
Smith-Waterman score: 568; 36.8% identity (55.7% similar) in 318 aa overlap (31-324:16-308)
10 20 30 40 50 60
pF1KB8 MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMTLNPLSSPYPPGGLPASPL
:: .. .::. .. :: : :
NP_001 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAG---GGYTAMPA
10 20 30 40
70 80 90 100 110 120
pF1KB8 PSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPY
: . . :: : .:: : . . : .: : .: .::::
NP_001 PMSVYSHPAHA----EQYPG----GMARAYGPYTPQP-------------QPKDMVKPPY
50 60 70 80
130 140 150 160 170 180
pF1KB8 SYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVAR
:::.:::::::.:: : .::. :::.::: ::.::.:.: :::::::.::.:.::::: :
NP_001 SYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPR
90 100 110 120 130 140
190 200 210 220
pF1KB8 SPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKK---------------GGSG
. ::::::::.: :.: :::::: .:::..::: .. :: : .
NP_001 DDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPPPGRQP
150 160 170 180 190 200
230 240 250 260 270
pF1KB8 AATTTRNGTGSAASTTTPAATVT-------SPPQPPPPAPEPEAQGGEDVGALD-CGSPA
. ... :.: . : . . . :.:: : : :. ...:. ::
NP_001 PPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPD
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB8 SSTPYFT-GLELPGELKLDAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGV
::. .. : :: : : ... : . ..: ::. . ::
NP_001 SSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAP-PPHHSQGFSVDNIMTSLRGS
270 280 290 300 310 320
340 350
pF1KB8 YYQGLYSRSLLNAS
NP_001 PQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGG
330 340 350 360 370 380
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 473 init1: 473 opt: 528 Z-score: 321.2 bits: 68.0 E(85289): 3.8e-11
Smith-Waterman score: 538; 36.3% identity (61.2% similar) in 281 aa overlap (62-340:5-265)
40 50 60 70 80 90
pF1KB8 PTMAPLNSYMTLNPLSSPYPPGGLPASPLPSGPLAPPAPAAPLGPTFPGLGVSGGSSSSG
::: :: : . . . : ...:
NP_004 MTAESGP-PPPQPEV-----LATVKEERGETAAG
10 20
100 110 120 130 140 150
pF1KB8 YGAPGPGLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLF
:.:: . .: . .::: ..:::::::.::.::: .:: . :::. ::..: . :
NP_004 AGVPGEATGRGAG-GRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITERF
30 40 50 60 70 80
160 170 180 190 200 210
pF1KB8 PYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQK
:.::.: ..:::::::.:..::::.:. : .::::.:::: :.. .:::.: .:::.:
NP_004 PFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSFLRRRK
90 100 110 120 130 140
220 230 240 250 260 270
pF1KB8 RFKLEEKVKKGGSGAATTTRNGTGSAASTTTPAATVTSPPQPPPPAPEPEAQGGEDVGAL
::: .. : . ......::.... ::... : : : .: :. .:
NP_004 RFK-----RSDLSTYPAYMHDAAAAAAAAAAAAAAAAIFPGAVP-AARPPYPGAVYAGYA
150 160 170 180 190 200
280 290 300 310 320
pF1KB8 DCGSPASSTPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTPAP--PKLDVGFGGYGA
: :. : . :: .. . ..:.: : ::: : . .:.. ::
NP_004 P-PSLAAPPPVYYPAASPGPCRVFGLVP-ERPLS-----PELGPAPSGPGGSCAFASAGA
210 220 230 240 250
330 340 350
pF1KB8 EGGEPGVYYQGLYSRSLLNAS
. : :
NP_004 PATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGS
260 270 280 290 300 310
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 550 init1: 457 opt: 523 Z-score: 316.8 bits: 67.6 E(85289): 6.6e-11
Smith-Waterman score: 536; 37.5% identity (59.0% similar) in 315 aa overlap (31-339:61-344)
10 20 30 40 50
pF1KB8 MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMT---LNPLSSPYPPGGLPA
:: :: .. .::. : .: :
NP_036 GDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGA
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB8 SPLPSGPL-APPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHA
. :.: . :: : . : :.:::. ..: :. : ::. .: ::. . .
NP_036 G--PGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSAG-GLAPSK--PKN-----SLV
100 110 120 130 140
120 130 140 150 160 170
pF1KB8 KPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFV
:::::::.:::::: :.: : :::: : ..: . ::::::. :::::::.::.:::::
NP_036 KPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFV
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB8 KVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGS
:. : : .::::.::.: :.: .::.:: .:::.:::: ... . . : :. :
NP_036 KIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALMMQSFGAYS
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB8 AASTTTPAATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDA
: ::. .. : : . .: : .: : . . :... ..:. : : :
NP_036 LA-----AAAGAAGPYGRPYGLHPAAAAG----AYSHPAAAAAAAAAAALQYPYALPPVA
270 280 290 300 310
300 310 320 330 340 350
pF1KB8 PYNFNHPFSINNLMSEQTPAPPKLDVGF--GGYGAEGGEPGVYYQGLYSRSLLNAS
: .. .: :. ..: ...:.. : ::. :
NP_036 P-----------VLPPAVPLLPSGELGRKAAAFGSQLG-PGLQLQLNSLGAAAAAAGTAG
320 330 340 350
NP_036 AAGTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSFLRP
360 370 380 390 400 410
350 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:43:10 2016 done: Fri Nov 4 16:43:11 2016
Total Scan time: 9.200 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]