Result of FASTA (omim) for
pF1KB8962
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8962, 342 aa
1>>>pF1KB8962 342 - 342 aa - 342 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3061+/-0.000369; mu= 4.4045+/- 0.023
mean_var=215.2439+/-42.562, 0's: 0 Z-trim(120.2): 195 B-trim: 121 in 2/54
Lambda= 0.087420
statistics sampled from 35017 (35234) to 35017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.413), width: 16
Scan time: 9.180
The best scores are: opt bits E(85289)
NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 2323 305.3 1.3e-82
NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 958 133.1 8.5e-31
NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 605 88.7 2.5e-17
NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 449 68.8 1.5e-11
NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 438 67.4 4e-11
NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 427 66.0 9.8e-11
NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 404 63.2 9.4e-10
NP_055027 (OMIM: 605559) homeobox protein Hox-C11 ( 304) 382 60.4 5.8e-09
NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313) 367 58.5 2.2e-08
NP_067015 (OMIM: 142986) homeobox protein Hox-D11 ( 338) 362 57.9 3.6e-08
XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 310 51.2 2.7e-06
NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 310 51.2 2.7e-06
XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 309 51.1 2.9e-06
NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 304 50.5 4.9e-06
NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 302 50.2 5.4e-06
NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 298 49.7 7.1e-06
NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 299 49.9 7.9e-06
NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 298 49.8 8.7e-06
NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 294 49.2 1e-05
NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 285 47.8 1.3e-05
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 294 49.4 1.4e-05
NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 290 48.8 1.7e-05
NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 285 48.0 2.2e-05
NP_776272 (OMIM: 142975) homeobox protein Hox-C12 ( 282) 283 47.9 3.2e-05
XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 281 47.5 3.2e-05
XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 281 47.5 3.2e-05
NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 281 47.5 3.2e-05
NP_004518 (OMIM: 214300,600147) homeobox protein M ( 254) 281 47.6 3.5e-05
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 281 47.6 3.5e-05
XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 281 47.6 3.8e-05
NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 278 47.4 6e-05
NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 275 46.9 6e-05
NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 275 46.9 6e-05
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 275 46.9 6.9e-05
NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 272 46.5 8.6e-05
NP_005513 (OMIM: 142955,601536) homeobox protein H ( 335) 272 46.6 9.3e-05
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 274 46.9 9.6e-05
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 274 46.9 9.6e-05
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 274 46.9 9.6e-05
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 274 46.9 9.6e-05
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 274 46.9 9.6e-05
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 274 46.9 9.6e-05
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 274 46.9 9.6e-05
NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 266 45.7 0.00012
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 271 46.5 0.00012
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 271 46.5 0.00012
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 271 46.5 0.00012
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 271 46.5 0.00012
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 271 46.5 0.00012
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 271 46.5 0.00012
>>NP_059105 (OMIM: 605560) homeobox protein Hox-C10 [Hom (342 aa)
initn: 2323 init1: 2323 opt: 2323 Z-score: 1604.2 bits: 305.3 E(85289): 1.3e-82
Smith-Waterman score: 2323; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342)
10 20 30 40 50 60
pF1KB8 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKRDEGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 SPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 KSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKERAKAADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 NPRAEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKERAKAADS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 SPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLE
250 260 270 280 290 300
310 320 330 340
pF1KB8 ISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
::::::::::::::::::::::::::::::::::::::::::
NP_059 ISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
310 320 330 340
>>NP_002139 (OMIM: 142984,192950) homeobox protein Hox-D (340 aa)
initn: 947 init1: 589 opt: 958 Z-score: 673.9 bits: 133.1 E(85289): 8.5e-31
Smith-Waterman score: 958; 50.5% identity (75.1% similar) in 321 aa overlap (25-342:28-340)
10 20 30 40 50
pF1KB8 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGS-DFNCGVMRGCGLAPSLSKR
:: ::.::: : :.. :. ::: :::.::
NP_002 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 DEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSA
: . ....:..: :. :.::: ::. . :.:::: . . .::. ..:::. :::::
NP_002 -EVNHQNMGMNVHP-YIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSD
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 EKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSALDKTPHCSGANDFEAPFE
.. . :. :.. .:::: :. :::::.:.: : .: : :: . . :. :.
NP_002 KRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTY-ATGKTQEYN--NSPEGSST
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 QRASLNPRAEHLESPQLGG-KVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKER
.::::. .:::.. .... . . . :.... .: . : : : ..
NP_002 VMLQLNPRGA--AKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEE-RSCL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 AKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT
:... :::.....:.:::::... :.::::::::::::::::::::::::::::::::::
NP_002 AEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT
240 250 260 270 280 290
300 310 320 330 340
pF1KB8 RERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
:::::::::..:::::::::::::::::::::.:::::::::.:..:.
NP_002 RERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
300 310 320 330 340
>>NP_061824 (OMIM: 142957) homeobox protein Hox-A10 [Hom (410 aa)
initn: 673 init1: 522 opt: 605 Z-score: 432.2 bits: 88.7 E(85289): 2.5e-17
Smith-Waterman score: 752; 42.1% identity (62.8% similar) in 368 aa overlap (17-342:49-410)
10 20 30 40
pF1KB8 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRG
:. ::: : .:.:. ..:. : ...
NP_061 SCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYG-LQS
20 30 40 50 60 70
50 60 70 80 90
pF1KB8 CGLAPSLS-KRDEGSSPS-------LALNTYPSYLSQLDSWGDPKAAYRLEQPVGRP---
::: :.:. ::.:..::. :. ... : .: : : . :.: : : :
NP_061 CGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPP
80 90 100 110 120 130
100 110 120 130
pF1KB8 ----------------LSSCSYPPSVKEENVCCMY-SAEKRAKSGPEAALYSH----PLP
.:::. ..:::. :.: ::.: : . :: . : :
NP_061 QQQPPPPPQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPP
140 150 160 170 180 190
140 150 160 170 180 190
pF1KB8 ESC-LGEHE-VPVPSYYRASPSY-SALDKTPHCSGANDFEA-PFEQRASLNPRAEHLESP
..: :: ::::.:.: : .: .: .::... : :: :. :. :
NP_061 DGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFP--AQPPGRGFDLPPA
200 210 220 230 240 250
200 210 220 230 240
pF1KB8 QLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKG------SPSESEKERAKAADSSPDT
.:... . .. .. : :. . : .: .: : : .:. ..:: .
NP_061 LASGSADAARKERALDSPPPPT--LACGSGGGSQGDEEAHASSSAAEELSPAPSESSKAS
260 270 280 290 300 310
250 260 270 280 290 300
pF1KB8 SDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKT
.... . :.::.. ::::::::::::::::::::::::::::::::::::::::::..
NP_061 PEKDSLGNSKGENAA-NWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRS
320 330 340 350 360 370
310 320 330 340
pF1KB8 INLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
..::::::::::::::::::::::::::::::.::::.
NP_061 VHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS
380 390 400 410
>>NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [Homo (260 aa)
initn: 439 init1: 418 opt: 449 Z-score: 328.5 bits: 68.8 E(85289): 1.5e-11
Smith-Waterman score: 470; 35.9% identity (60.2% similar) in 259 aa overlap (95-334:6-258)
70 80 90 100 110 120
pF1KB8 ALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGP
:.:. ....: . : . . :
NP_008 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHP
10 20 30
130 140 150 160 170 180
pF1KB8 EAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRA
:: : .:. : . : :. .:. . . .: : .. :. . :. .
NP_008 AAARPSGLVPD-C---SDFPSCSFA-PKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADT
40 50 60 70 80 90
190 200 210 220 230
pF1KB8 EHLES--PQLGGKVSFPETPKSDSQTP-SPNEIKTEQSLAGPK----------GSPSESE
..... :.: :::: : . . .:. ... :: :::.:
NP_008 RYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGEL-
100 110 120 130 140
240 250 260 270 280
pF1KB8 KERAKAADSSPD------TSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEK
..:: . ::. .. .: : .. : ..::. :.: :::::::::.:::::::
NP_008 RDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEK
150 160 170 180 190 200
290 300 310 320 330 340
pF1KB8 EFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
::::::::::.:: :.....:::.:::::::::::::.::::.:. .:
NP_008 EFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
210 220 230 240 250 260
>>NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [Homo (272 aa)
initn: 446 init1: 392 opt: 438 Z-score: 320.7 bits: 67.4 E(85289): 4e-11
Smith-Waterman score: 438; 40.9% identity (63.1% similar) in 203 aa overlap (134-329:69-267)
110 120 130 140 150 160
pF1KB8 SVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPH
: : . ::. :.. . ..:
NP_689 PRQAATLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 CSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSF---PETPKSDSQTPSPNEIKTEQSL
..: : . .:. :.: : : .. . :: : : . :. ::
NP_689 AAAAPDGRY---MRSWLEPTPGALSFAGLPSSRPYGIKPE-PLSARRGDCPTLDTHTLSL
100 110 120 130 140 150
230 240 250 260 270
pF1KB8 AGPK-GSPSESEKERAKAADSSPDTSDNEA---KEEIKAENTTGNWLTAKSGRKKRCPYT
. ::: ..... . . : ....::. : : .: ..::: :.: ::::::::
NP_689 TDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYT
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 KHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELT
:::::::::::::::::::.:: :... .:::.:::::::::::::.::.:..
NP_689 KHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
220 230 240 250 260 270
340
pF1KB8 SNFNFT
>>NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [Homo (250 aa)
initn: 429 init1: 404 opt: 427 Z-score: 313.7 bits: 66.0 E(85289): 9.8e-11
Smith-Waterman score: 451; 42.2% identity (64.9% similar) in 211 aa overlap (140-329:43-246)
110 120 130 140 150 160
pF1KB8 VCCMYSAEKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSA--LDKTPHCSG
:: : : :. .: ..: .:: ::
NP_076 DSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASG
20 30 40 50 60 70
170 180 190 200 210 220
pF1KB8 A-NDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNE--IKTEQSLAGP
. . :. : .. : :: : .. . .:.... .:. .. .:.: :..:
NP_076 SLPSVYHPYIQPQGVPP----AESRYL--RTWLEPAPRGEA-APGQGQAAVKAEPLLGAP
80 90 100 110 120
230 240 250 260
pF1KB8 -----KGSPSES-EKERAKAA---DSSPDTSDN------EAKEEIKAENTTGNWLTAKSG
.:.: : : .. : .. : .:: : ::. : ..::: :.:.
NP_076 GELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSS
130 140 150 160 170 180
270 280 290 300 310 320
pF1KB8 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNR
:::::::::.:::::::::::::::::.:: :... .::..:::::::::::::.::::.
NP_076 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK
190 200 210 220 230 240
330 340
pF1KB8 ENRIRELTSNFNFT
:
NP_076 EQGKE
250
>>NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [Homo (352 aa)
initn: 437 init1: 384 opt: 404 Z-score: 296.1 bits: 63.2 E(85289): 9.4e-10
Smith-Waterman score: 422; 38.5% identity (61.5% similar) in 213 aa overlap (122-329:150-346)
100 110 120 130 140
pF1KB8 VGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVP-----
::: . . ::. . .:.:
NP_055 MEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPET----RAAPAPATAAS
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 SYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDS
. .: : :. .: .:: : . .. . : : .. . :: : .
NP_055 TTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGG-----TGPGAGI
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 QTPSPNEIKTEQSLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTAK
. . . ..: : . . :. : ::. : :.:. .... .: ..::. :.
NP_055 GAATGTGGSSEPSACSDHPIPGCSLKEEEKQ-HSQPQ------QQQLDPNNPAANWIHAR
240 250 260 270 280
270 280 290 300 310 320
pF1KB8 SGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKM
: :::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.:::
NP_055 STRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKM
290 300 310 320 330 340
330 340
pF1KB8 NRENRIRELTSNFNFT
..:
NP_055 SKEKCPKGD
350
>>NP_055027 (OMIM: 605559) homeobox protein Hox-C11 [Hom (304 aa)
initn: 361 init1: 306 opt: 382 Z-score: 281.9 bits: 60.4 E(85289): 5.8e-09
Smith-Waterman score: 382; 32.4% identity (58.4% similar) in 315 aa overlap (39-338:2-301)
10 20 30 40 50 60
pF1KB8 PNSYAEPLAAPGGGERYSRSAGMYMQSGSDFNCGVMRGCGLAPSLSKR--DEGSSPSLAL
:: .: : .:: ..: : : : :
NP_055 MFN-SVNLGNFCSPSRKERGADFGERGSCAS
10 20 30
70 80 90 100 110
pF1KB8 NTY-PS---YLSQLDSWGD--PKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAE--K
: : :: :. .... .. :.: : .. : :. . :: :.: . :.. .
NP_055 NLYLPSCTYYMPEFSTVSSFLPQAPSR---QISYPYSA-QVPP-VREVSYGLEPSGKWHH
40 50 60 70 80
120 130 140 150 160 170
pF1KB8 RAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPSYSALDK--TPHCSGANDFEAPFEQ
: . . : .. . . :: : . .. ::.. . .:: . :. : . ..
NP_055 RNSYSSCYAAADELMHRECLPPSTV-TEILMKNEGSYGGHHHPSAPHATPAG-FYSSVNK
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB8 RASLNPRA--EHLESPQLGGKVSFPETPKSDS-QTPSPNEIKTEQSLAGPKGSPSESEKE
. : :.: . ... :: : : : . .. . : ..::. . .:.: :
NP_055 NSVL-PQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAE
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB8 RAKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYL
. .. :: .. . ::: : : .: :::::::.: : :::.::.::.:.
NP_055 EENTNPSSSGSAHSVAKEPAK-----GAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYI
210 220 230 240 250
300 310 320 330 340
pF1KB8 TRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
..:.::..:. .::::::::::::::::: ::..:. :.. ...:
NP_055 NKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRD-RLQYFSGNPLL
260 270 280 290 300
>>NP_005514 (OMIM: 142958,605432) homeobox protein Hox-A (313 aa)
initn: 403 init1: 311 opt: 367 Z-score: 271.5 bits: 58.5 E(85289): 2.2e-08
Smith-Waterman score: 387; 32.3% identity (57.4% similar) in 303 aa overlap (60-338:23-310)
30 40 50 60 70 80
pF1KB8 GMYMQSGSDFNCGVMRGCGLAPSLSKRDEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLE
:.:... . ::.: : : .: .
NP_005 MDFDERGPCSSNMYLPSCTYYVSGPDFS--SLPSFLPQTPSSRPMTYSYSSN
10 20 30 40 50
90 100 110 120 130
pF1KB8 QPVGRPLSSCSY-----PPSVKEE---NVCCMYSAEKRAK----SGPEAA-LYSHPLPES
: .:. .. :..: . :. ::::. .. ..: :: . . : .:
NP_005 LPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKS
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB8 CLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKV
. .. :.:. .: ::.. .. : : : . : .: :.: : . :
NP_005 SANVYHHPTPAV--SSNFYSTVGRNGVLPQAFD---QFFETAYGTP--ENLASSDYPGDK
120 130 140 150 160
200 210 220 230 240
pF1KB8 SFPETPKSDSQTPSPNEIK------TEQSLAGPKGSPSES-----EKERAKAADSSPDTS
: . : . . : . : .: .: :. :. :::: . .:: .
NP_005 SAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 DNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTI
.. .. : :: ...: . :::::::::.: :::.::.:..:...:.::..:. .
NP_005 SSSGHTEDKAGGSSG-----QRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRML
230 240 250 260 270
310 320 330 340
pF1KB8 NLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
::::::::::::::::: ::.::. :.. ..:
NP_005 NLTDRQVKIWFQNRRMKEKKINRD-RLQYYSANPLL
280 290 300 310
>>NP_067015 (OMIM: 142986) homeobox protein Hox-D11 [Hom (338 aa)
initn: 391 init1: 318 opt: 362 Z-score: 267.7 bits: 57.9 E(85289): 3.6e-08
Smith-Waterman score: 362; 34.2% identity (60.7% similar) in 234 aa overlap (115-338:112-335)
90 100 110 120 130 140
pF1KB8 AYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVP
.: : .. :::. . :: . :.. :
NP_067 GSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPA--GRR--P
90 100 110 120 130
150 160 170 180 190 200
pF1KB8 VPSYYRASPSYSALDKTPH--CSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETP
..: : :: ..:..: . . . : ... : . :. :
NP_067 -DVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPP
140 150 160 170 180 190
210 220 230 240 250
pF1KB8 KSDSQTPSP----NEIKTEQSLAGPKGSPSESE---KERAKAADSSPDTSDNEAKE-EIK
. :.: .. . . .: ::: . .: ::..: .:.:. :
NP_067 PPPAP-PQPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEGS--GGDGEGPPGEAG
200 210 220 230 240 250
260 270 280 290 300 310
pF1KB8 AENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKI
::.... .. . .:::::::::.: :::.::.::.:...:.::..:. .:::::::::
NP_067 AEKSSSA-VAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKI
260 270 280 290 300 310
320 330 340
pF1KB8 WFQNRRMKLKKMNRENRIRELTSNFNFT
:::::::: ::.::. :.. .:.:
NP_067 WFQNRRMKEKKLNRD-RLQYFTGNPLF
320 330
342 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:42:38 2016 done: Fri Nov 4 16:42:40 2016
Total Scan time: 9.180 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]