Result of FASTA (omim) for
pF1KB8960
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8960, 340 aa
1>>>pF1KB8960 340 - 340 aa - 340 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9813+/-0.000378; mu= 9.8003+/- 0.024
mean_var=155.2881+/-32.013, 0's: 0 Z-trim(118.2): 212 B-trim: 1647 in 2/53
Lambda= 0.102921
statistics sampled from 30700 (30965) to 30700 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.363), width: 16
Scan time: 8.670
The best scores are: opt bits E(85289)
NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 2271 348.8 9.7e-96
NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 958 153.9 4.8e-37
NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 604 101.4 3.6e-21
NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 439 76.8 7.7e-14
NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 432 75.6 1.2e-13
NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 431 75.5 1.4e-13
NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 419 73.7 5e-13
NP_055027 (OMIM: 605559) homeobox protein Hox-C11 ( 304) 337 61.6 2.5e-09
NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313) 328 60.3 6.5e-09
NP_067015 (OMIM: 142986) homeobox protein Hox-D11 ( 338) 328 60.3 6.8e-09
NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 313 58.0 2.7e-08
XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 305 56.8 5.7e-08
NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 305 56.8 5.7e-08
XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 304 56.6 6.4e-08
NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 293 55.1 2.2e-07
NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 292 54.9 2.5e-07
NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 289 54.4 2.8e-07
NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 287 54.1 3.7e-07
NP_001186676 (OMIM: 142985) homeobox protein Hox-D ( 106) 279 52.6 4.6e-07
XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 283 53.5 5.2e-07
NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 283 53.5 5.2e-07
XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 283 53.5 5.2e-07
XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 283 53.6 6.2e-07
NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 277 52.6 1.1e-06
NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 277 52.6 1.1e-06
NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 275 52.3 1.2e-06
NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 275 52.4 1.4e-06
NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 271 51.7 1.8e-06
NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 264 50.7 3.8e-06
NP_067016 (OMIM: 142988) homeobox protein Hox-D12 ( 270) 263 50.6 4.7e-06
NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 259 49.7 4.7e-06
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 263 50.6 5.3e-06
NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 259 49.9 6.4e-06
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 262 50.6 7.3e-06
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 262 50.6 7.3e-06
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 262 50.6 7.3e-06
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 262 50.6 7.3e-06
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 262 50.6 7.3e-06
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 262 50.6 7.3e-06
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 262 50.6 7.3e-06
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 262 50.6 7.3e-06
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 257 49.7 8.3e-06
NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 256 49.5 9.1e-06
NP_776272 (OMIM: 142975) homeobox protein Hox-C12 ( 282) 255 49.4 1.1e-05
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 49.9 1.2e-05
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 49.9 1.2e-05
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 257 49.9 1.2e-05
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 257 49.9 1.2e-05
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 49.9 1.2e-05
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 49.9 1.2e-05
>>NP_002139 (OMIM: 142984,192950) homeobox protein Hox-D (340 aa)
initn: 2271 init1: 2271 opt: 2271 Z-score: 1839.8 bits: 348.8 E(85289): 9.7e-96
Smith-Waterman score: 2271; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340)
10 20 30 40 50 60
pF1KB8 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 EVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEIS
250 260 270 280 290 300
310 320 330 340
pF1KB8 KSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
::::::::::::::::::::::::::::::::::::::::
NP_002 KSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
310 320 330 340
>>NP_059105 (OMIM: 605560) homeobox protein Hox-C10 [Hom (342 aa)
initn: 947 init1: 589 opt: 958 Z-score: 786.1 bits: 153.9 E(85289): 4.8e-37
Smith-Waterman score: 958; 50.5% identity (75.1% similar) in 321 aa overlap (28-340:25-342)
10 20 30 40 50 60
pF1KB8 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKR
:: ::.::: : :.. :. ::: :::.::
NP_059 MTCPRNVTPNSYAEPLAAPGGGERYSRSAGMYMQSGS-DFNCGVMRGCGLAPSLSKR
10 20 30 40 50
70 80 90 100 110
pF1KB8 -EVNHQNMGMNVHP-YIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSD
: . ....:..: :. :.::: ::. . :.:::: . . .::. ..:::. :::::
NP_059 DEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 KRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTY-ATGKTQEYN--NSPEGSST
.. . :. :.. .:::: :. :::::.:.: : .: : :: . . :. :.
NP_059 EKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSALDKTPHCSGANDFEAPFE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 VMLQLNPRGA--AKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEE-RSCL
.::::. .:::.. .... . . . :.... .: . : : : ..
NP_059 QRASLNPRAEHLESPQLGG-KVSFPETPKSDSQTPSPNEIKTEQSLAGPKGSPSESEKER
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 AEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT
:... :::.....:.:::::... :.::::::::::::::::::::::::::::::::::
NP_059 AKAADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT
240 250 260 270 280 290
300 310 320 330 340
pF1KB8 RERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
:::::::::..:::::::::::::::::::::.:::::::::.:..:.
NP_059 RERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
300 310 320 330 340
>>NP_061824 (OMIM: 142957) homeobox protein Hox-A10 [Hom (410 aa)
initn: 864 init1: 514 opt: 604 Z-score: 501.0 bits: 101.4 E(85289): 3.6e-21
Smith-Waterman score: 802; 46.1% identity (65.7% similar) in 362 aa overlap (28-340:57-410)
10 20 30 40 50
pF1KB8 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSL
: . ...:.:: .::. ::.:.:::.:.:
NP_061 NSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPP-AADL-PYGLQSCGLFPTL
30 40 50 60 70 80
60 70 80 90
pF1KB8 A-KREVNHQ--------NMGMNVHPYIPQ-VDSWTDPNRSCRIEQP-----VTQQVP---
. ::. . ..: ..: : :. .: : : ::::.: : :: :
NP_061 GGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPP
90 100 110 120 130 140
100 110 120 130 140
pF1KB8 -----------TCSFTTNIKEESNCCMY--SDKRNKL--ISAEVPSYQRLVP-ESCPV-E
.:::. ::::::. :.: .:: :. .::. . : : ..: .
NP_061 PQPPQPAPQATSCSFAQNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGT
150 160 170 180 190 200
150 160 170 180 190
pF1KB8 NPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVM---LQLNPRGAA---KPQLSAAQLQ
. :::::::::::.:.:.: :... :.. . . .: : . : :.... .
NP_061 SSGVPVPGYFRLSQAYGTAKG--YGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSAD
210 220 230 240 250 260
200 210 220 230 240
pF1KB8 MEKKMNEPVSGQEPTKV------SQV-ESPEAKGGLPEERS-CLAEVSVSSPEVQEKESK
.: : :: . :: : .:... :: : .: : .::: :.:
NP_061 AARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPE---KDSL
270 280 290 300 310
250 260 270 280 290 300
pF1KB8 EEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDR
. :... ..::::::::::::::::::::::::::::::::::::::::::.::.::::
NP_061 GNSKGEN-AANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDR
320 330 340 350 360 370
310 320 330 340
pF1KB8 QVKIWFQNRRMKLKKMSRENRIRELTANLTFS
::::::::::::::::.:::::::::::..::
NP_061 QVKIWFQNRRMKLKKMNRENRIRELTANFNFS
380 390 400 410
>>NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [Homo (352 aa)
initn: 468 init1: 385 opt: 439 Z-score: 369.5 bits: 76.8 E(85289): 7.7e-14
Smith-Waterman score: 443; 30.6% identity (56.9% similar) in 353 aa overlap (5-327:12-346)
10 20 30 40
pF1KB8 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPP-PSADMGTYGMQ---
.:: . ... :::::. .. : :. . :: :.:. :.
NP_055 MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVF----AARFGPPGPGAQGRPAGVADGP
10 20 30 40 50
50 60 70 80
pF1KB8 --------TCGLLP-----SLAKREVNHQ-----NMGMNVHPYIPQ---VDSWTDPNRSC
.:.. : : . : : :. :::.: . : ..:.:
NP_055 AATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYV
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB8 RIEQPVTQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPV
: . . : .: . .. . :. . :. : . :. .:.
NP_055 R-----SWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHY--GIKPETRAAPA
120 130 140 150 160
150 160 170 180 190 200
pF1KB8 PGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNEPVSGQ
:. ..: ....:. ..: . .: . .:.. :..: .. ...: ..:
NP_055 PA--TAASTTSSSSTSLSSSSKRTECSVARE--SQGSSGPEFSCNSF-LQEKAAAATGGT
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB8 EPTKVSQVESPEAKGGLPEERSC----LAEVSVSSPEVQEKE-SKEEIKSDTPTSNWLTA
: . . . . :: : .: . :.. : :... ..... ..:..::. :
NP_055 GPG--AGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB8 KSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKK
.: :::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.::
NP_055 RSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKK
290 300 310 320 330 340
330 340
pF1KB8 MSRENRIRELTANLTFS
::.:
NP_055 MSKEKCPKGD
350
>>NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [Homo (250 aa)
initn: 478 init1: 401 opt: 432 Z-score: 365.8 bits: 75.6 E(85289): 1.2e-13
Smith-Waterman score: 436; 39.5% identity (65.0% similar) in 220 aa overlap (125-327:35-246)
100 110 120 130 140 150
pF1KB8 TQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSY-QRLVPESCPVENPEVPVPG--Y
:.. :.. ..: :: . :..:: : .
NP_076 GTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQ-PKAPVFGASW
10 20 30 40 50 60
160 170 180 190 200
pF1KB8 FRLSQTYATGKTQEYNN---SPEGSSTV-------MLQLNPRGAAKPQLSAAQLQMEKKM
:: .:.:. . .:.: . :. ::: : : . : .. : .
NP_076 APLSP-HASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLL
70 80 90 100 110 120
210 220 230 240 250
pF1KB8 NEPVSGQEPTKVSQVESPEAKGG----LPEERSCLAEVSVSSPEVQEKESKEEIKSDTPT
. : :. . . : :...: : ..: .. .. . .:.::. . .:.
NP_076 GAP--GELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKIC----EGSEDKERPDQTNPS
130 140 150 160 170
260 270 280 290 300 310
pF1KB8 SNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNR
.::: :.:.:::::::::.:::::::::::::::::.:: :... .::..::::::::::
NP_076 ANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNR
180 190 200 210 220 230
320 330 340
pF1KB8 RMKLKKMSRENRIRELTANLTFS
:::.:::..:
NP_076 RMKMKKMNKEQGKE
240 250
>>NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [Homo (260 aa)
initn: 466 init1: 411 opt: 431 Z-score: 364.7 bits: 75.5 E(85289): 1.4e-13
Smith-Waterman score: 435; 39.4% identity (66.2% similar) in 216 aa overlap (134-332:43-258)
110 120 130 140 150 160
pF1KB8 TTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVEN-PEVPVPGYFRLSQTYATGK
:::. . .: :. : : . . ..
NP_008 DSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQ
20 30 40 50 60 70
170 180 190 200 210
pF1KB8 T----QEYNNSPE-GSSTVMLQ--LNP-RGAAK-PQLSAAQLQMEKKMNEPVSGQEPTKV
. . :. .:. :..: ... :.: ::.. :.. :. .. : . . .
NP_008 SSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGP
80 90 100 110 120 130
220 230 240 250 260
pF1KB8 SQVES-PEAKGGLPEERSCLAEVSVSSPEV------QEKESKEEIKSDTPTSNWLTAKSG
.. .: :. : : : : .. :::. ..:: : .. ..:..::. :.:
NP_008 GEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARST
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB8 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSR
:::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.:::..
NP_008 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNK
200 210 220 230 240 250
330 340
pF1KB8 ENRIRELTANLTFS
:. .:
NP_008 EKTDKEQS
260
>>NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [Homo (272 aa)
initn: 431 init1: 383 opt: 419 Z-score: 354.9 bits: 73.7 E(85289): 5e-13
Smith-Waterman score: 419; 53.4% identity (73.7% similar) in 133 aa overlap (203-327:135-267)
180 190 200 210 220
pF1KB8 SSTVMLQLNPRGAAKPQLSAAQLQMEKKMNEPVS---GQEPTKVSQVES--PEAKGGLPE
::.: :. :: ... : : :. :
NP_689 GRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPV
110 120 130 140 150 160
230 240 250 260 270 280
pF1KB8 ERSCLAEVSVSSPEVQEKES---KEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKE
.: .. : . :.:: : : ..:..::: :.: ::::::::::::::::::
NP_689 DREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKE
170 180 190 200 210 220
290 300 310 320 330 340
pF1KB8 FLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
:::::::::.:: :... .:::.:::::::::::::.::....
NP_689 FLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
230 240 250 260 270
>>NP_055027 (OMIM: 605559) homeobox protein Hox-C11 [Hom (304 aa)
initn: 356 init1: 308 opt: 337 Z-score: 288.4 bits: 61.6 E(85289): 2.5e-09
Smith-Waterman score: 341; 30.6% identity (55.9% similar) in 304 aa overlap (41-336:20-301)
20 30 40 50 60
pF1KB8 NTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGL-LPSLAKREVNHQNMGM
::.: : . .: ::: . . ..
NP_055 MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYMPEFST---
10 20 30 40
70 80 90 100 110 120
pF1KB8 NVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVP
: ..::. :.: .: : . ::: .. : :. . .. .. .:
NP_055 -VSSFLPQA-----PSR--QISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADE
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 SYQR-LVPESCPVE---NPEVPVPGYFRLSQTYATGKTQEYNNSPEG--SSTVMLQLNPR
..: .: : .: . : :. . : .:: : : ::. .. :.
NP_055 LMHRECLPPSTVTEILMKNEGSYGGHHHPSAPHAT---------PAGFYSSVNKNSVLPQ
100 110 120 130 140
190 200 210 220 230 240
pF1KB8 GAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPE-ERSCLAEVSVSSPEV
. . .: . . : ::. .: .. :.: :.: . : . ::. . .
NP_055 AFDRFFDNAYCGGGDPPAEPPCSGKGEAK-GEPEAPPASGLASRAEAGAEAEAEEENTNP
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB8 QEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKS
. . : . . .. . .: :::::::.: : :::.::.::.:...:.::..:.
NP_055 SSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRM
210 220 230 240 250 260
310 320 330 340
pF1KB8 VNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
.::::::::::::::::: ::.::. :.. ...:
NP_055 LNLTDRQVKIWFQNRRMKEKKLSRD-RLQYFSGNPLL
270 280 290 300
>>NP_005514 (OMIM: 142958,605432) homeobox protein Hox-A (313 aa)
initn: 374 init1: 303 opt: 328 Z-score: 281.1 bits: 60.3 E(85289): 6.5e-09
Smith-Waterman score: 328; 28.0% identity (54.8% similar) in 314 aa overlap (31-336:10-310)
10 20 30 40 50 60
pF1KB8 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKR
:..::.: : . . : . .: ::. .
NP_005 MDFDERGPCSSNMYLP--SCTYYVSGPDFSSL-PSFLPQ
10 20 30
70 80 90 100 110 120
pF1KB8 EVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKR
. . : .. .:::. . . .:.:. : ... . : .. :
NP_005 TPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEE--LVHRDCL
40 50 60 70 80 90
130 140 150 160 170
pF1KB8 NKLISAEVPSYQRLVPESCPVENPEVP-VPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQ
. .: ::. . :. : : . .: : . : . : ... : . . .
NP_005 QAPSAAGVPG-DVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPEN
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 LNPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSS
: . :: . . ... : . . : .. :: .: :.....
NP_005 LASSDYPGDK-SAEKGPPAATATSAAAAAAATGAPATSSSDSGGG----GGC-RETAAAA
160 170 180 190 200
240 250 260 270 280 290
pF1KB8 PEVQEKESKEEIKSDTPTSNWLTAKSG-------RKKRCPYTKHQTLELEKEFLFNMYLT
: .... : .: .:. :.: :::::::::.: :::.::.:..:..
NP_005 EEKERRRRPESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYIN
210 220 230 240 250 260
300 310 320 330 340
pF1KB8 RERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
.:.::..:. .::::::::::::::::: ::..:. :.. .::
NP_005 KEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRD-RLQYYSANPLL
270 280 290 300 310
>>NP_067015 (OMIM: 142986) homeobox protein Hox-D11 [Hom (338 aa)
initn: 354 init1: 310 opt: 328 Z-score: 280.6 bits: 60.3 E(85289): 6.8e-09
Smith-Waterman score: 335; 34.8% identity (62.6% similar) in 187 aa overlap (168-339:155-338)
140 150 160 170 180 190
pF1KB8 SCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQM
..: :... . . :.. :: . :. .
NP_067 MQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQ-GFDQF-Y
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB8 EKKMNEPVSGQEPTKVSQVESPEAKGGLPEERSCL-----AEVSVSSPEVQEKESKEEIK
: . : .: .: .::. . . :. . . ..: . : . :
NP_067 EAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEGSG
190 200 210 220 230 240
260 270 280 290 300
pF1KB8 SD---TP-------TSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKS
.: : .:. .. . .:::::::::.: :::.::.::.:...:.::..:.
NP_067 GDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRM
250 260 270 280 290 300
310 320 330 340
pF1KB8 VNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
.::::::::::::::::: ::..:. :.. .:.: :
NP_067 LNLTDRQVKIWFQNRRMKEKKLNRD-RLQYFTGNPLF
310 320 330
340 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:42:00 2016 done: Fri Nov 4 16:42:01 2016
Total Scan time: 8.670 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]