FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8950, 324 aa 1>>>pF1KB8950 324 - 324 aa - 324 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0716+/-0.000782; mu= 6.7603+/- 0.048 mean_var=223.1304+/-46.611, 0's: 0 Z-trim(116.3): 164 B-trim: 937 in 1/52 Lambda= 0.085861 statistics sampled from 16764 (16938) to 16764 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.52), width: 16 Scan time: 2.890 The best scores are: opt bits E(32554) CCDS4387.1 5 gene_id:1482|Hs108|chr5 ( 324) 2213 286.0 2.8e-77 CCDS54949.1 5 gene_id:1482|Hs108|chr5 ( 151) 746 103.9 8.4e-23 CCDS54950.1 5 gene_id:1482|Hs108|chr5 ( 112) 742 103.3 9.6e-23 CCDS41558.1 3 gene_id:159296|Hs108|chr10 ( 364) 713 100.2 2.6e-21 CCDS42855.1 4 gene_id:644524|Hs108|chr20 ( 354) 480 71.3 1.3e-12 CCDS13145.1 2 gene_id:4821|Hs108|chr20 ( 273) 466 69.5 3.5e-12 CCDS9660.1 8 gene_id:26257|Hs108|chr14 ( 239) 433 65.3 5.4e-11 >>CCDS4387.1 5 gene_id:1482|Hs108|chr5 (324 aa) initn: 2213 init1: 2213 opt: 2213 Z-score: 1500.8 bits: 286.0 E(32554): 2.8e-77 Smith-Waterman score: 2213; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324) 10 20 30 40 50 60 pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 YGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 YGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDL 250 260 270 280 290 300 310 320 pF1KB8 NAVQSPGIPQSNSGVSTLHGIRAW :::::::::::::::::::::::: CCDS43 NAVQSPGIPQSNSGVSTLHGIRAW 310 320 >>CCDS54949.1 5 gene_id:1482|Hs108|chr5 (151 aa) initn: 742 init1: 742 opt: 746 Z-score: 522.9 bits: 103.9 E(32554): 8.4e-23 Smith-Waterman score: 746; 95.8% identity (96.6% similar) in 118 aa overlap (1-118:1-117) 10 20 30 40 50 60 pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV ::::::::::::::::::::::::::::::::::::::::::::::::::: : : . CCDS54 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKG-CELPRGQ 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST CCDS54 RPPVLFSSALSQPDFLQMLSETCRWLPVHLAE 120 130 140 150 >>CCDS54950.1 5 gene_id:1482|Hs108|chr5 (112 aa) initn: 742 init1: 742 opt: 742 Z-score: 521.8 bits: 103.3 E(32554): 9.6e-23 Smith-Waterman score: 742; 100.0% identity (100.0% similar) in 111 aa overlap (1-111:1-111) 10 20 30 40 50 60 pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKA 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST >>CCDS41558.1 3 gene_id:159296|Hs108|chr10 (364 aa) initn: 680 init1: 491 opt: 713 Z-score: 496.0 bits: 100.2 E(32554): 2.6e-21 Smith-Waterman score: 861; 47.3% identity (65.2% similar) in 376 aa overlap (1-324:2-364) 10 20 30 40 50 pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYA-G :.::: .: ::::::::::::::.. . .: .:.: :: . . ::::: . .. : CCDS41 MMLPSP-VTSTPFSVKDILNLEQQHQHFHGA-HLQADLEHHFHSAPCMLAAAEGTQFSDG 10 20 30 40 50 60 70 80 90 100 pF1KB8 PEAAAPG-------LPELRAELGRAPSPAKCASAFPAA----PAFYPRAYSD-PDPAKDP : : : : :.. : . : ... . :. . . :. ..: CCDS41 GEEDEEDEGEKLSYLNSLAAADGHGDS-GLCPQGYVHTVLRDSCSEPKEHEEEPEVVRD- 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 RAEKKELCALQKAVEL--EKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLS :..:. : :.:..: . :...:::. : :::::::::::::.::::::::::::: CCDS41 RSQKS--CQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 APERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLV ::::..::: :::::::::::::::::::::::::..::: : ::::: ::.:::::: CCDS41 APEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLEL-GAHAPPPPP-RRVAVPVLV 180 190 200 210 220 230 230 240 250 260 pF1KB8 RDGKPCLGDSAP-YAPAYGVGLNPYGYNAYPAYPGYGG---------------AACSPGY ::::::. :: :. :.:: . :.::..::: :::. :: : .: CCDS41 RDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAY-GYGNSAAAAAAAAAAAAAAAAYSSSY 240 250 260 270 280 290 270 280 290 300 310 pF1KB8 SCTAAYPAG-----------PSPAQPATAAANNN-FVNFGVGDLNAVQSPGIPQ-----S .: ::::: . ::: .::... ::: :..:.. : : : . CCDS41 GC--AYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVN--VSNLGGFGSGGSAQPLHQGT 300 310 320 330 340 320 pF1KB8 NSGVS----TLHGIRAW .:.. ::.::::: CCDS41 AAGAACAQGTLQGIRAW 350 360 >>CCDS42855.1 4 gene_id:644524|Hs108|chr20 (354 aa) initn: 484 init1: 335 opt: 480 Z-score: 340.2 bits: 71.3 E(32554): 1.3e-12 Smith-Waterman score: 484; 42.7% identity (62.9% similar) in 248 aa overlap (9-236:51-294) 10 20 30 pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLE : : .. .. .: : : ::. .: CCDS42 EETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAA 30 40 50 60 70 80 40 50 60 70 80 pF1KB8 ATLAPSSCMLAAFK--PEAYAGPEAAAP-----GLPELRAELGRAPSPAKCASA---FPA :. : .. :... : . :..: :: .. .:: . . ..: . : CCDS42 AAAAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNM-GELPAYTDGMRGGAATGWYGA 90 100 110 120 130 90 100 110 120 130 140 pF1KB8 APAFYPRAYSDPDPAKDPRA--EKKELCALQKAVELEKTEAD-NAERPRARRRRKPRVLF : :: ::. . : : . . .: .. :. . .: : ::: :::: CCDS42 NPD--PR-YSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLF 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB8 SQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELV :::::::::::::::.:::::::..:::...:: :::::::::.::: ::: .:.. . . CCDS42 SQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQL 200 210 220 230 240 250 210 220 230 240 250 pF1KB8 ----GL-PPPPPPPA-RRIAVPVLVRDGKPCL-GDSAPYAPAYGVGLNPYGYNAYPAYPG :: :::::::. ::.::::::.::::: : :.: CCDS42 QQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELS 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB8 YGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTL CCDS42 PSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW 320 330 340 350 >>CCDS13145.1 2 gene_id:4821|Hs108|chr20 (273 aa) initn: 383 init1: 348 opt: 466 Z-score: 332.2 bits: 69.5 E(32554): 3.5e-12 Smith-Waterman score: 466; 36.9% identity (60.2% similar) in 279 aa overlap (8-275:6-264) 10 20 30 40 50 60 pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE : : :::::::.: . . ....: : . .: .: ::: CCDS13 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPE--EENEGP--------EPAKRAGPL 10 20 30 40 70 80 90 100 110 pF1KB8 A-----AAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCA . :. .:: . .: : . . .. . : .: ... : : CCDS13 GQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSA 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 LQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVL .. . ..: . ... : ..:: :::::.::.:::::::.::::::::::..:::.. CCDS13 DESPDNDKETPGGGGD---AGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLI 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 KLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSA .:: :::::::::.::: :: : .. .:.. :: : ::.:::::::::::: . .: CCDS13 RLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSP-----RRVAVPVLVRDGKPCHALKA 170 180 190 200 210 220 240 250 260 270 280 pF1KB8 P--YAPAYGVGLNPYGYNA----YPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAAN : .. .:. .:.: . : . ..: .: : .:.: CCDS13 QDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQY--PTAHPLVQAQQWTW 230 240 250 260 270 290 300 310 320 pF1KB8 NNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW >>CCDS9660.1 8 gene_id:26257|Hs108|chr14 (239 aa) initn: 470 init1: 318 opt: 433 Z-score: 310.8 bits: 65.3 E(32554): 5.4e-11 Smith-Waterman score: 480; 41.0% identity (55.4% similar) in 249 aa overlap (59-289:18-238) 30 40 50 60 70 80 pF1KB8 AAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPA :: : ::. . : :::.: ::. . . CCDS96 MATSGRLSFTVRSLLDLPEQDAQHLPRREPE-PRAPQPDPCAAWLDS 10 20 30 40 90 100 110 120 130 pF1KB8 APAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRAR---------RRR . :: :: . :: . :...:: :: .:. CCDS96 ERGHYPS--SDESS-------------------LETSPPDSSQRPSARPASPGSDAEKRK 50 60 70 80 140 150 160 170 180 190 pF1KB8 KPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQD : :::::.::. ::::::.::::::::::.::::.:.:: :::::::::.::: :: : CCDS96 KRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAP 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB8 QTLELVGLPPPP-----PPPARRIAVPVLVRDGKPCLG----DSAPYAPAYGVGLNPYGY . : : : ::..::::::::.:: : . . : : : . CCDS96 GAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAPPAAA 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB8 NAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQ :.::..: :: : . .:: :.:: .. : CCDS96 CPLPGYPAFG-----PG-SALGLFPAYQHLASPALVSWNW 210 220 230 320 pF1KB8 SNSGVSTLHGIRAW 324 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:47:53 2016 done: Sat Nov 5 00:47:54 2016 Total Scan time: 2.890 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]