FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8947, 314 aa
  1>>>pF1KB8947 314 - 314 aa - 314 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3719+/-0.000938; mu= 15.4659+/- 0.056
 mean_var=67.4953+/-13.770, 0's: 0 Z-trim(105.4): 21  B-trim: 0 in 0/50
 Lambda= 0.156112
 statistics sampled from 8377 (8384) to 8377 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.258), width:  16
 Scan time:  2.470

The best scores are:                                      opt bits E(32554)
CCDS12093.1 SLC39A3 gene_id:29985|Hs108|chr19      ( 314) 1976 454.0  7e-128
CCDS45909.1 SLC39A3 gene_id:29985|Hs108|chr19      ( 105)  455 111.2 3.7e-25
CCDS1055.1 SLC39A1 gene_id:27173|Hs108|chr1        ( 324)  382 95.0 8.5e-20
CCDS9563.1 SLC39A2 gene_id:29986|Hs108|chr14       ( 309)  355 88.9 5.5e-18


>>CCDS12093.1 SLC39A3 gene_id:29985|Hs108|chr19           (314 aa)
 initn: 1976 init1: 1976 opt: 1976  Z-score: 2409.4  bits: 454.0 E(32554): 7e-128
Smith-Waterman score: 1976; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314)

               10        20        30        40        50        60
pF1KB8 MVKLLVAKILCMVGVFFFMLLGSLLPVKIIETDFEKAHRSKKILSLCNTFGGGVFLATCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MVKLLVAKILCMVGVFFFMLLGSLLPVKIIETDFEKAHRSKKILSLCNTFGGGVFLATCF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 NALLPAVREKLQKVLSLGHISTDYPLAETILLLGFFMTVFLEQLILTFRKEKPSFIDLET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 NALLPAVREKLQKVLSLGHISTDYPLAETILLLGFFMTVFLEQLILTFRKEKPSFIDLET
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FNAGSDVGSDSEYESPFMGGARGHALYVEPHGHGPSLSVQGLSRASPVRLLSLAFALSAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 FNAGSDVGSDSEYESPFMGGARGHALYVEPHGHGPSLSVQGLSRASPVRLLSLAFALSAH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 SVFEGLALGLQEEGEKVVSLFVGVAVHETLVAVALGISMARSAMPLRDAAKLAVTVSAMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SVFEGLALGLQEEGEKVVSLFVGVAVHETLVAVALGISMARSAMPLRDAAKLAVTVSAMI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 PLGIGLGLGIESAQGVPGSVASVLLQGLAGGTFLFITFLEILAKELEEKSDRLLKVLFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PLGIGLGLGIESAQGVPGSVASVLLQGLAGGTFLFITFLEILAKELEEKSDRLLKVLFLV
              250       260       270       280       290       300

              310    
pF1KB8 LGYTVLAGMVFLKW
       ::::::::::::::
CCDS12 LGYTVLAGMVFLKW
              310    

>>CCDS45909.1 SLC39A3 gene_id:29985|Hs108|chr19           (105 aa)
 initn: 478 init1: 454 opt: 455  Z-score: 565.1  bits: 111.2 E(32554): 3.7e-25
Smith-Waterman score: 455; 84.9% identity (93.0% similar) in 86 aa overlap (1-85:1-86)

               10        20        30        40        50        60
pF1KB8 MVKLLVAKILCMVGVFFFMLLGSLLPVKIIETDFEKAHRSKKILSLCNTFGGGVFLATCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MVKLLVAKILCMVGVFFFMLLGSLLPVKIIETDFEKAHRSKKILSLCNTFGGGVFLATCF
               10        20        30        40        50        60

               70         80        90       100       110         
pF1KB8 NALLPAVREKLQKVLSLGH-ISTDYPLAETILLLGFFMTVFLEQLILTFRKEKPSFIDLE
       ::::::::::..   .:.  ..: .:                                  
CCDS45 NALLPAVREKVRAPWALAAALGTLWPRDSDAFSTLMPSSVKALML               
               70        80        90       100                    

>>CCDS1055.1 SLC39A1 gene_id:27173|Hs108|chr1             (324 aa)
 initn: 598 init1: 346 opt: 382  Z-score: 468.9  bits: 95.0 E(32554): 8.5e-20
Smith-Waterman score: 575; 34.5% identity (66.1% similar) in 316 aa overlap (5-313:27-323)

                                     10        20        30        
pF1KB8                       MVKLLVAKILCMVGVFFFMLLGSLLPVKIIE---TDFE
                                 : .:.  .: .. . :: ::.:. ...   .. :
CCDS10 MGPWGEPELLVWRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHE
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KB8 KAHRSKKILSLCNTFGGGVFLATCFNALLPAVREKLQKVLSLGHISTDYPLAETILLLGF
        .   .: ::: . :.::::::::.  :::     ....:.  :.. ..:: : :: .::
CCDS10 GSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGF
               70        80        90       100       110       120

         100       110        120       130       140       150    
pF1KB8 FMTVFLEQLILTFRKEK-PSFIDLETFNAGSDVGSDSEYESPFMGGARGHALYVEPHGH-
       :... .::. :...... ::   ::   :             ..: . :       : : 
CCDS10 FLVLVMEQITLAYKEQSGPS--PLEETRA-------------LLGTVNGG----PQHWHD
              130       140                      150           160 

           160         170       180       190       200       210 
pF1KB8 GPSLSVQGLSRASP--VRLLSLAFALSAHSVFEGLALGLQEEGEKVVSLFVGVAVHETLV
       ::..   . . :.:  .:   :.:.:. ::::::::.:::..  ... : ... .:. ..
CCDS10 GPGVPQASGAPATPSALRACVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGIL
             170       180       190       200       210       220 

             220       230       240       250       260       270 
pF1KB8 AVALGISMARSAMPLRDAAKLAVTVSAMIPLGIGLGLGIESAQGVPGSVASVLLQGLAGG
       ::.:.. . .: .  . .:  ..  : : ::::::: ..  . :   ..:. .:.:.:.:
CCDS10 AVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAG
             230       240       250       260       270       280 

             280       290       300       310    
pF1KB8 TFLFITFLEILAKELEEKSDRLLKVLFLVLGYTVLAGMVFLKW
       :::.::::::: .::  . .:.:::..:. :...:.:..:.. 
CCDS10 TFLYITFLEILPQELASSEQRILKVILLLAGFALLTGLLFIQI
             290       300       310       320    

>>CCDS9563.1 SLC39A2 gene_id:29986|Hs108|chr14            (309 aa)
 initn: 352 init1: 153 opt: 355  Z-score: 436.4  bits: 88.9 E(32554): 5.5e-18
Smith-Waterman score: 423; 32.1% identity (60.9% similar) in 327 aa overlap (1-307:1-303)

               10        20          30        40        50        
pF1KB8 MVKLLVAKILCMVGVFFFMLLGSLLPV--KIIETDFEKAHRSKKILSLCNTFGGGVFLAT
       : .::  :. :. ... . :  .: :.  : .. :  ..:. . .: : . ...::::..
CCDS95 MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAARGHH-RLVLRLLGCISAGVFLGA
               10        20        30        40         50         

       60            70                  80           90       100 
pF1KB8 CFNAL----LPAVREKLQKVL----------SLGHIST---DYPLAETILLLGFFMTVFL
        :  .    :  .. ..:: .          : :  ..   .:: .: :. ::::.. ::
CCDS95 GFMHMTAEALEEIESQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFL
      60        70        80        90       100       110         

             110       120       130       140       150       160 
pF1KB8 EQLILTFRKEKPSFIDLETFNAGSDVGSDSEYESPFMGGARGHALYVEPHGHGPSLSVQG
       :.: :   .  :.        ::... .: :.     :::  : . .. ::: :: : .:
CCDS95 ESLAL---QCCPG-------AAGGSTVQDEEW-----GGA--HIFELHSHGHLPSPS-KG
     120                 130       140              150        160 

             170       180       190       200       210       220 
pF1KB8 LSRASPVRLLSLAFALSAHSVFEGLALGLQEEGEKVVSLFVGVAVHETLVAVALGISMAR
            :.: : : ..:: ::::::::.:::     .:.: ..: .:. ::. ..:. ...
CCDS95 -----PLRALVLLLSLSFHSVFEGLAVGLQPTVAATVQLCLAVLAHKGLVVFGVGMRLVH
                  170       180       190       200       210      

             230       240       250        260       270       280
pF1KB8 SAMPLRDAAKLAVTVSAMIPLGIGLGLGIESAQGVPG-SVASVLLQGLAGGTFLFITFLE
        .   : :.   . .. : :::...::.. ....  : ..:...:.:.:.::::..::::
CCDS95 LGTSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLE
        220       230       240       250       260       270      

              290       300       310    
pF1KB8 ILAKELEEKSDRLLKVLFLVLGYTVLAGMVFLKW
       :: .::      : :   .. :.. .:       
CCDS95 ILPRELASPEAPLAKWSCVAAGFAFMAFIALWA 
        280       290       300          




314 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:38:02 2016 done: Fri Nov  4 16:38:03 2016
 Total Scan time:  2.470 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]