FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8946, 313 aa
  1>>>pF1KB8946 313 - 313 aa - 313 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7177+/-0.000798; mu= 7.6166+/- 0.049
 mean_var=194.1893+/-40.743, 0's: 0 Z-trim(115.2): 146  B-trim: 905 in 2/49
 Lambda= 0.092037
 statistics sampled from 15559 (15718) to 15559 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.483), width:  16
 Scan time:  2.680

The best scores are:                                      opt bits E(32554)
CCDS5411.1 HOXA11 gene_id:3207|Hs108|chr7          ( 313) 2110 291.7 4.8e-79
CCDS2265.1 HOXD11 gene_id:3237|Hs108|chr2          ( 338)  547 84.2 1.5e-16
CCDS8867.1 HOXC11 gene_id:3227|Hs108|chr12         ( 304)  518 80.3   2e-15


>>CCDS5411.1 HOXA11 gene_id:3207|Hs108|chr7               (313 aa)
 initn: 2110 init1: 2110 opt: 2110  Z-score: 1532.5  bits: 291.7 E(32554): 4.8e-79
Smith-Waterman score: 2110; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)

               10        20        30        40        50        60
pF1KB8 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 TFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 AVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 AVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 AAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 AAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKIN
              250       260       270       280       290       300

              310   
pF1KB8 RDRLQYYSANPLL
       :::::::::::::
CCDS54 RDRLQYYSANPLL
              310   

>>CCDS2265.1 HOXD11 gene_id:3237|Hs108|chr2               (338 aa)
 initn: 871 init1: 507 opt: 547  Z-score: 410.5  bits: 84.2 E(32554): 1.5e-16
Smith-Waterman score: 900; 48.5% identity (63.1% similar) in 355 aa overlap (2-313:3-338)

                10        20        30        40        50         
pF1KB8  MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNL-PQVQPVR
         :::: :  ...::::.:.:::.  ::.: :::: : :::  ::. ::::: :.:::::
CCDS22 MNDFDECGQSAASMYLPGCAYYVAPSDFASKPSFLSQ-PSSCQMTFPYSSNLAPHVQPVR
               10        20        30         40        50         

       60        70                                           80   
pF1KB8 EVTFREYAIEPATKWHPRGN-----------------------------------LAHCY
       ::.::.:..: : ::  ::.                                    :   
CCDS22 EVAFRDYGLERA-KWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAA
      60        70         80        90       100       110        

            90       100       110       120            130        
pF1KB8 SAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP-----AVSSNFYSTVGRNGVLPQ
       .::: . .  :  :  ::   ::: :.   :   : :     ...:::::.:::::.:::
CCDS22 AAEEAAMQRELLPP--AGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQ
      120       130         140       150       160       170      

      140       150       160       170       180       190        
pF1KB8 AFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGG
       .::::.:.: : :       . : .     ::   :     .::  : : :..   ::::
CCDS22 GFDQFYEAAPGPP-------FAGPQ-----PPPPPAPPQPEGAADKGDPRTGA---GGGG
        180              190            200       210          220 

      200       210       220         230       240       250      
pF1KB8 GCRETAAAAEEKERRRRPESSSSPESSSGHT--EDKAGGSSGQRTRKKRCPYTKYQIREL
       :   : :.   . .     :... :.  :..  : .... . ::.:::::::::::::::
CCDS22 GSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIREL
             230       240       250       260       270       280 

        260       270       280       290       300       310   
pF1KB8 EREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
       ::::::.:::::::::::::::::::::::::::::::::::.:::::::...:::.
CCDS22 EREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
             290       300       310       320       330        

>>CCDS8867.1 HOXC11 gene_id:3227|Hs108|chr12              (304 aa)
 initn: 769 init1: 480 opt: 518  Z-score: 390.3  bits: 80.3 E(32554): 2e-15
Smith-Waterman score: 959; 52.5% identity (72.6% similar) in 318 aa overlap (2-313:21-304)

                                  10        20        30        40 
pF1KB8                    MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSR
                           :: ::: :.::.::::::::.  :.::.. :::::.:: :
CCDS88 MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYM--PEFSTVSSFLPQAPS-R
               10        20        30        40          50        

              50        60        70        80         90       100
pF1KB8 PMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSA-EELVHRDCLQAPSAA
        ..: ::.   :: :::::.   :..::. ::: :.. . ::.: .::.::.::  ::..
CCDS88 QISYPYSA---QVPPVREVS---YGLEPSGKWHHRNSYSSCYAAADELMHRECLP-PSTV
        60           70           80        90       100        110

              110          120        130       140        150     
pF1KB8 GVPGDVLAKSSANV--YHHPT-P-AVSSNFYSTVGRNGVLPQAFDQFFETAY-GTPENLA
           ..: :. ..   .:::. : :. ..:::.:..:.:::::::.::..:: :  .  :
CCDS88 ---TEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPA
                 120       130       140       150       160       

         160       170       180       190       200       210     
pF1KB8 SSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRR
            : :.  :: : :  .:. :. : .:: :                   : .:.   
CCDS88 EPPCSG-KGEAKGEPEAPPASGLASRAEAGAEA-------------------EAEEENTN
       170        180       190                          200       

         220       230       240       250       260       270     
pF1KB8 PESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLS
       : ::.: .: . .   :... .. :::::::::.:.:::::::::::.::::::::::::
CCDS88 PSSSGSAHSVAKEPA-KGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLS
       210       220        230       240       250       260      

         280       290       300       310   
pF1KB8 RMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
       :::::::::::::::::::::::..::::::.:.::::
CCDS88 RMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL
        270       280       290       300    




313 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:37:28 2016 done: Fri Nov  4 16:37:28 2016
 Total Scan time:  2.680 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]