Result of FASTA (omim) for
pF1KB8942
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8942, 301 aa
1>>>pF1KB8942 301 - 301 aa - 301 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0937+/-0.000323; mu= 5.1047+/- 0.020
mean_var=221.3630+/-45.245, 0's: 0 Z-trim(122.9): 248 B-trim: 0 in 0/59
Lambda= 0.086203
statistics sampled from 41600 (41886) to 41600 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.491), width: 16
Scan time: 7.890
The best scores are: opt bits E(85289)
NP_001129743 (OMIM: 217095,611770) homeobox protei ( 301) 2099 273.0 5.1e-73
NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 718 101.3 2.7e-21
NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 ( 364) 656 93.6 6.2e-19
NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 ( 273) 506 74.8 2.1e-13
XP_006723629 (OMIM: 604612) PREDICTED: homeobox pr ( 202) 493 73.1 5.2e-13
NP_001180 (OMIM: 602183,613330) homeobox protein N ( 333) 390 60.5 5.3e-09
NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 ( 354) 383 59.6 1e-08
NP_003308 (OMIM: 118700,188550,600635,610978) home ( 371) 373 58.4 2.5e-08
NP_001073136 (OMIM: 118700,188550,600635,610978) h ( 401) 373 58.5 2.6e-08
NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 ( 239) 322 51.9 1.5e-06
NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 316 51.1 2.4e-06
NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 319 51.7 2.5e-06
NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 310 50.2 3.1e-06
NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 312 50.8 4.5e-06
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 312 50.9 5.4e-06
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 312 50.9 5.4e-06
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 312 50.9 5.4e-06
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 312 50.9 5.4e-06
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 312 50.9 5.4e-06
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 312 50.9 5.4e-06
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 312 50.9 5.4e-06
NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 295 48.6 1.6e-05
XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 288 47.7 3e-05
NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 288 47.7 3e-05
NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 286 47.5 3.9e-05
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 286 47.6 4.2e-05
NP_005211 (OMIM: 104510,190320,600525) homeobox pr ( 287) 284 47.2 4.4e-05
NP_004396 (OMIM: 126255) homeobox protein DLX-2 [H ( 328) 285 47.4 4.4e-05
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 279 46.7 7.9e-05
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 275 46.2 0.00011
NP_835221 (OMIM: 600029) homeobox protein DLX-1 is ( 255) 270 45.5 0.00014
NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 271 45.6 0.00014
NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 271 45.7 0.00016
XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 271 45.7 0.00016
XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 272 45.9 0.00016
XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 271 45.8 0.00018
XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 271 45.8 0.00018
XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 271 45.8 0.00018
NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 271 45.8 0.00018
XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 271 45.8 0.00018
XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 271 45.8 0.00018
XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 271 45.9 0.0002
XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 271 45.9 0.00022
>>NP_001129743 (OMIM: 217095,611770) homeobox protein Nk (301 aa)
initn: 2099 init1: 2099 opt: 2099 Z-score: 1431.8 bits: 273.0 E(85289): 5.1e-73
Smith-Waterman score: 2099; 100.0% identity (100.0% similar) in 301 aa overlap (1-301:1-301)
10 20 30 40 50 60
pF1KB8 MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 QNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 YSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRA
250 260 270 280 290 300
pF1KB8 W
:
NP_001 W
>>NP_004378 (OMIM: 108900,187500,217095,225250,600584,61 (324 aa)
initn: 652 init1: 424 opt: 718 Z-score: 503.2 bits: 101.3 E(85289): 2.7e-21
Smith-Waterman score: 759; 45.2% identity (64.8% similar) in 330 aa overlap (1-301:1-324)
10 20 30 40 50
pF1KB8 MLLSP-VTSTPFSVKDILRLERE-RSCPAA---SPHPRVRKSPENFQYLRMDAEPRGSEV
:. :: .: ::::::::: ::.. :: :: : . .. .: . . . : ..
NP_004 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 HNAGGGGGDRKLDGSEPPGGPCEAVLEMDA----ERMGEPQPGLNAASPLGGGTRVPERG
: : : : : . : ... . ...:.: : .: . ..
NP_004 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDP---AKDPRAEKKELCALQ
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 VGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQL
. ..... .:.:.::.::::::::::::: ::::::::::::::::..:::.:.:
NP_004 KAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKL
120 130 140 150 160 170
180 190 200 210 220
pF1KB8 TSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTP----RRVAVPVLVRDGKPCLGPG-PG
::::::::::::::::::::::..:::.: : : ::.:::::::::::::: . :
NP_004 TSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPY
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 APAFP---SPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAG------
:::. .:: . . : : ::.:: . :: .: :. :.::.: : ..:.
NP_004 APAYGVGLNPY--GYNAYPAYPGYGGAACSPGY-SCTAAYPAGPSPAQPATAAANNNFVN
240 250 260 270 280 290
280 290 300
pF1KB8 FGHGGQNAT-----PQGHLA-ATLQGVRAW
:: : ::. ::.. . .::.:.:::
NP_004 FGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
300 310 320
>>NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 [Hom (364 aa)
initn: 671 init1: 510 opt: 656 Z-score: 460.9 bits: 93.6 E(85289): 6.2e-19
Smith-Waterman score: 722; 46.7% identity (68.3% similar) in 306 aa overlap (1-289:2-298)
10 20 30 40
pF1KB8 MLLSPVTSTPFSVKDILRLERERS------CPAASPH-----PRVRKSPENFQYL---R
:: :::::::::::::: ::.... : : : . . :. :. .
NP_660 MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 MDAEPRGSEVHNAGG-GGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGG
: : .: .. .. ...: . :.. : : ..::. . . : . ... .
NP_660 EDEEDEGEKLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 TRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREH
. .... ..:: . .::.:: :.:::::::::::::. ::::::::::::::::::
NP_660 SCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREH
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 LASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGH--PLTPRRVAVPVLVRDGKPCLG
:::.:.::::::::::::::::::::::::::::..: : ::::::::::::::::.
NP_660 LASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKPCVT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 PGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGG
: .: :. .:::...: :: :.. : . :::. :.: .. : . :.:... .
NP_660 P--SAQAYGAPYSVGASAYS----YNSFP-AYGYGNSAAAAAAAAA--AAAAAAAYSSSY
250 260 270 280 290
290 300
pF1KB8 QNATPQGHLAATLQGVRAW
: : :
NP_660 GCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAAGA
300 310 320 330 340 350
>>NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 [Hom (273 aa)
initn: 484 init1: 349 opt: 506 Z-score: 361.7 bits: 74.8 E(85289): 2.1e-13
Smith-Waterman score: 509; 40.4% identity (61.0% similar) in 282 aa overlap (7-276:6-268)
10 20 30 40 50 60
pF1KB8 MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGG
:.: ::::::: : . . . : ..::. : .: : . .:
NP_002 MSLTNTKTGFSVKDILDLP-----DTNDEEGSVAEGPEE--------ENEGPEPAKRAG
10 20 30 40
70 80 90 100 110
pF1KB8 GGGDRKLDG--SEPPGGPCEAVLEMDAERMGEPQPGLN--------AASPLGGGTRVPER
:. ::. : : .: . : ::. .: : .... ::
NP_002 PLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 GVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQ
.. .: :. . . : ..:: :::::.::. :::::.::::::::::::::: ..
NP_002 SADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 LTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAF
:: :::::::::.::: :: : .:..:.. : .:::::::::::::::: . :
NP_002 LTPTQVKIWFQNHRYKMKRARAEKGMEVTPLP-SPRRVAVPVLVRDGKPCHALKAQDLA-
170 180 190 200 210 220
240 250 260 270 280
pF1KB8 PSPYSAAVSPYSCYGGYS--GAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQ
. ..:.. :.: :.. : :.: :.. :..:. :. : ::..:
NP_002 AATFQAGI-PFSAYSAQSLQHMQYNAQYSS--ASTPQYPTAH-PLVQAQQWTW
230 240 250 260 270
290 300
pF1KB8 GHLAATLQGVRAW
>>XP_006723629 (OMIM: 604612) PREDICTED: homeobox protei (202 aa)
initn: 453 init1: 349 opt: 493 Z-score: 354.6 bits: 73.1 E(85289): 5.2e-13
Smith-Waterman score: 493; 48.9% identity (71.5% similar) in 186 aa overlap (94-276:18-197)
70 80 90 100 110 120
pF1KB8 DRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNA-ASPLGGGTRVPERGVGNSGDSVRGG
:: : : : .... :: .. .: :. .
XP_006 MIFSATSPPKFSPTLLHGLAAGAPPQDSSSKSPEPSADESPDNDKET
10 20 30 40
130 140 150 160 170 180
pF1KB8 RSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQN
. : ..:: :::::.::. :::::.::::::::::::::: ..:: :::::::::
XP_006 PGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQN
50 60 70 80 90 100
190 200 210 220 230 240
pF1KB8 RRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYS
.::: :: : .:..:.. : .:::::::::::::::: . : . ..:.. :.:
XP_006 HRYKMKRARAEKGMEVTPLP-SPRRVAVPVLVRDGKPCHALKAQDLA-AATFQAGI-PFS
110 120 130 140 150 160
250 260 270 280 290 300
pF1KB8 CYGGYS--GAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRA
:.. : :.: :.. :..:. :. : ::..:
XP_006 AYSAQSLQHMQYNAQYSS--ASTPQYPTAH-PLVQAQQWTW
170 180 190 200
pF1KB8 W
>>NP_001180 (OMIM: 602183,613330) homeobox protein Nkx-3 (333 aa)
initn: 347 init1: 282 opt: 390 Z-score: 282.6 bits: 60.5 E(85289): 5.3e-09
Smith-Waterman score: 395; 39.3% identity (60.7% similar) in 247 aa overlap (37-258:98-332)
10 20 30 40 50 60
pF1KB8 TSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGGGGGDRK
: :: . : :. ::. .:: .::. .
NP_001 DSLLASPAGTRTAAGRTAESPEGWDSDSALSEEN-ESRRRCADARGAS--GAGLAGGSLS
70 80 90 100 110 120
70 80 90 100 110
pF1KB8 L-----------DGSEPPGGPCEAVLEMDAERMGEPQPGL--NAASPLGGGTRVPERGVG
: : : .: .. ::.: :. .: ....: :. . . :.:
NP_001 LGQPVCELAASKDLEEEAAGRSDS--EMSASVSGDRSPRTEDDGVGPRGAHVSALCSGAG
130 140 150 160 170 180
120 130 140 150 160
pF1KB8 NSGDSVRGGRSEQ------PKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLAS
..: : .: .:. :: :..:. :. ::.:::. :::::..:::::.::: ::.
NP_001 GGGGSGPAGVAEEEEEPAAPKPRKKRS-RAAFSHAQVFELERRFNHQRYLSGPERADLAA
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB8 ALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPG---
.:.:: ::::::::::::: ::... .: ::. : . ..::: ::::: . ::
NP_001 SLKLTETQVKIWFQNRRYKTKRRQMAADL-LASAP-AAKKVAVKVLVRDDQRQYLPGEVL
250 260 270 280 290
230 240 250 260 270 280
pF1KB8 -PGA--PAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHG
: . : :: : :: : :.. . .:. ::
NP_001 RPPSLLPLQPSYYY----PYYCLPGWALSTCAAAAGTQ
300 310 320 330
290 300
pF1KB8 GQNATPQGHLAATLQGVRAW
>>NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 [Hom (354 aa)
initn: 569 init1: 332 opt: 383 Z-score: 277.6 bits: 59.6 E(85289): 1e-08
Smith-Waterman score: 474; 45.1% identity (62.5% similar) in 224 aa overlap (88-301:152-354)
60 70 80 90 100 110
pF1KB8 AGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGD
:: :. :.:.:. .:. : :.....
NP_149 PAYTDGMRGGAATGWYGANPDPRYSSISRFMG-PSAGVNVAG-MGSLT-----GIADAAK
130 140 150 160 170
120 130 140 150 160 170
pF1KB8 SVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVK
:. .. : ::: ::::::::: ::::::::.:::::::::::: ..:: ::::
NP_149 SLGPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVK
180 190 200 210 220 230
180 190 200 210 220
pF1KB8 IWFQNRRYKCKRQRQDKS---LELAGH-------PLTPRRVAVPVLVRDGKPCLGPGPGA
:::::.::: ::: .::. :. : : .::::::::::.::::: . ::
NP_149 IWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQN---GA
240 250 260 270 280 290
230 240 250 260 270 280
pF1KB8 PAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATP
. :.: .:. .: :: : .:: :: : : .. . .. .
NP_149 ST-PTPGQAGPQP--------PAPTPAP--ELEELSPSPPALHGPGGGLAALDAAAGEYS
300 310 320 330 340
290 300
pF1KB8 QGHLAATLQGVRAW
: :.:.: :.:
NP_149 GGVLGANLLYGRTW
350
>>NP_003308 (OMIM: 118700,188550,600635,610978) homeobox (371 aa)
initn: 496 init1: 332 opt: 373 Z-score: 270.6 bits: 58.4 E(85289): 2.5e-08
Smith-Waterman score: 498; 36.8% identity (54.1% similar) in 353 aa overlap (1-297:1-342)
10 20 30 40
pF1KB8 MLLSPVTSTPFSVKDILR-LERE------------------RSCPAASPHPRVRKSPENF
: .:: .:::::.::: ::. :. :: : ... .
NP_003 MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPTAAMQQHAVGH
10 20 30 40 50 60
50 60 70 80 90
pF1KB8 Q-----YLRMDAEPRGSEVHNAGGGGGDRKLDG-SEPPGGPCEAVLEMDAERMG----EP
. .: : . :.: :: . .: . :: : : . ... .: : .:
NP_003 HGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELP--PYQDTMRNSASGPGWYGANP
70 80 90 100 110
100 110 120 130 140
pF1KB8 QPGLNAAS----PLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLAL
.: . : : : .: . :.:. :: : . . :.: ::: ::::::::: :
NP_003 DPRFPAISRFMGPASGMNMSGMGGLGSLGD-VSKNMAPLPSA-PRRKRRVLFSQAQVYEL
120 130 140 150 160 170
150 160 170 180 190
pF1KB8 ERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLEL---------
:::::::.:::::::::::: ..:: :::::::::.::: ::: .::. .
NP_003 ERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGG
180 190 200 210 220 230
200 210 220 230 240
pF1KB8 -----AGHPL-------TPRRVAVPVLVRDGKPCLG--PGPGAPAFPSPYSAAVSPYSCY
.: : .::::::::::.::::: . :.::: .. . . .. .
NP_003 GGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQA
240 250 260 270 280 290
250 260 270 280 290 300
pF1KB8 GGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW
. ..: ..: : :: : : . : ..: . :.: :.:::
NP_003 AQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAH--HAASP-----AALQGQVSSLSH
300 310 320 330 340
NP_003 LNSSGSDYGTMSCSTLLYGRTW
350 360 370
>>NP_001073136 (OMIM: 118700,188550,600635,610978) homeo (401 aa)
initn: 496 init1: 332 opt: 373 Z-score: 270.2 bits: 58.5 E(85289): 2.6e-08
Smith-Waterman score: 498; 36.8% identity (54.1% similar) in 353 aa overlap (1-297:31-372)
10 20
pF1KB8 MLLSPVTSTPFSVKDILR-LERE-------
: .:: .:::::.::: ::.
NP_001 MWSGGSGKARGWEAAAGGRSSPGRLSRRRIMSMSPKHTTPFSVSDILSPLEESYKKVGME
10 20 30 40 50 60
30 40 50 60
pF1KB8 -----------RSCPAASPHPRVRKSPENFQ-----YLRMDAEPRGSEVHNAGGGGGDRK
:. :: : ... . . .: : . :.: :: . .
NP_001 GGGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGN
70 80 90 100 110 120
70 80 90 100 110
pF1KB8 LDG-SEPPGGPCEAVLEMDAERMG----EPQPGLNAAS----PLGGGTRVPERGVGNSGD
: . :: : : . ... .: : .:.: . : : : .: . :.:. ::
NP_001 LGNMSELP--PYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGD
130 140 150 160 170
120 130 140 150 160 170
pF1KB8 SVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVK
: . . :.: ::: ::::::::: ::::::::.:::::::::::: ..:: ::::
NP_001 -VSKNMAPLPSA-PRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVK
180 190 200 210 220 230
180 190 200 210
pF1KB8 IWFQNRRYKCKRQRQDKSLEL--------------AGHPL-------TPRRVAVPVLVRD
:::::.::: ::: .::. . .: : .::::::::::.:
NP_001 IWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKD
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB8 GKPCLG--PGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLA
:::: . :.::: .. . . .. . . ..: ..: : :: : : .
NP_001 GKPCQAGAPAPGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQ
300 310 320 330 340 350
280 290 300
pF1KB8 SAGFGHGGQNATPQGHLAATLQGVRAW
: ..: . :.: :.:::
NP_001 SPDLAH--HAASP-----AALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW
360 370 380 390 400
>>NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 [Hom (239 aa)
initn: 451 init1: 289 opt: 322 Z-score: 238.7 bits: 51.9 E(85289): 1.5e-06
Smith-Waterman score: 430; 43.3% identity (58.1% similar) in 203 aa overlap (65-255:28-217)
40 50 60 70 80 90
pF1KB8 RKSPENFQYLRMDAEPRGSEVHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPG
:. . : :: : : :.:: :.
NP_055 MATSGRLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWL--DSERGHYPSSD
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 LNA--ASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFK
.. .:: .. : : .. ..: :..:.: :::::.::.: :::::.
NP_055 ESSLETSPPDSSQRPSARPASPGSD-----------AEKRKKRRVLFSKAQTLELERRFR
60 70 80 90 100
160 170 180 190 200
pF1KB8 QQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQD---------KSLELAGHPL
:::::::::::.::: :.:: :::::::::.::: :: : : :: . :
NP_055 QQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB8 TPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAP-YGAGYGTCYAG
:::.::::::::.:: : : : . . .: . : : .: :
NP_055 LLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFP
170 180 190 200 210 220
270 280 290 300
pF1KB8 APSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW
NP_055 AYQHLASPALVSWNW
230
301 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:36:23 2016 done: Fri Nov 4 16:36:24 2016
Total Scan time: 7.890 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]