Result of FASTA (omim) for
pF1KB8929
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8929, 281 aa
1>>>pF1KB8929 281 - 281 aa - 281 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1703+/-0.000338; mu= -0.0941+/- 0.021
mean_var=262.9100+/-52.748, 0's: 0 Z-trim(124.1): 11 B-trim: 817 in 1/58
Lambda= 0.079099
statistics sampled from 45120 (45131) to 45120 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.833), E-opt: 0.2 (0.529), width: 16
Scan time: 7.080
The best scores are: opt bits E(85289)
NP_001796 (OMIM: 245480,600749) CCAAT/enhancer-bin ( 281) 1930 232.4 7.5e-61
NP_001272807 (OMIM: 189965) CCAAT/enhancer-binding ( 322) 438 62.2 1.5e-09
NP_005185 (OMIM: 189965) CCAAT/enhancer-binding pr ( 345) 438 62.2 1.6e-09
NP_001272758 (OMIM: 116897,601626) CCAAT/enhancer- ( 239) 412 59.1 9.4e-09
NP_001274364 (OMIM: 116897,601626) CCAAT/enhancer- ( 344) 412 59.2 1.2e-08
NP_004355 (OMIM: 116897,601626) CCAAT/enhancer-bin ( 358) 412 59.2 1.3e-08
NP_001274353 (OMIM: 116897,601626) CCAAT/enhancer- ( 393) 412 59.3 1.3e-08
NP_001272808 (OMIM: 189965) CCAAT/enhancer-binding ( 147) 400 57.5 1.7e-08
NP_005186 (OMIM: 116898) CCAAT/enhancer-binding pr ( 269) 387 56.3 7.4e-08
>>NP_001796 (OMIM: 245480,600749) CCAAT/enhancer-binding (281 aa)
initn: 1930 init1: 1930 opt: 1930 Z-score: 1213.4 bits: 232.4 E(85289): 7.5e-61
Smith-Waterman score: 1930; 100.0% identity (100.0% similar) in 281 aa overlap (1-281:1-281)
10 20 30 40 50 60
pF1KB8 MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESGEEQLLSDLFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESGEEQLLSDLFAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KPAPEARGLKGPGTPAFPHYLPPDPRPFAYPPHTFGPDRKALGPGIYSSPGSYDPRAVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPAPEARGLKGPGTPAFPHYLPPDPRPFAYPPHTFGPDRKALGPGIYSSPGSYDPRAVAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KEEPRGPEGSRAASRGSYNPLQYQVAHCGQTAMHLPPTLAAPGQPLRVLKAPLATAAPPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEEPRGPEGSRAASRGSYNPLQYQVAHCGQTAMHLPPTLAAPGQPLRVLKAPLATAAPPC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SPLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYM
190 200 210 220 230 240
250 260 270 280
pF1KB8 AENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
:::::::::::::::::::::::::::::::::::::::::
NP_001 AENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
250 260 270 280
>>NP_001272807 (OMIM: 189965) CCAAT/enhancer-binding pro (322 aa)
initn: 464 init1: 362 opt: 438 Z-score: 292.5 bits: 62.2 E(85289): 1.5e-09
Smith-Waterman score: 478; 37.1% identity (55.3% similar) in 313 aa overlap (13-280:18-322)
10 20 30 40
pF1KB8 MSHGTYYECEPRGGQQ-PLEFSGGRAGP----GELGDMCEHEASIDLSAYIES-G
::. : ..: :: ::::.. .:: .::.: :.: :
NP_001 MEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPAGELGSIGDHERAIDFSPYLEPLG
10 20 30 40 50 60
50 60 70 80 90
pF1KB8 EEQ-----LLSDLF-AVKPAPE-ARGLKGPGTPAFPHYLPPD--------PRPFAYPP-H
: .: : :. ::: : . .: . . : : ..:
NP_001 APQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSDLFSDDYGGKNCKKPAEYGYVSLG
70 80 90 100 110 120
100 110 120 130
pF1KB8 TFGPDRKALGPGIYSS-----------------PGSYDPRAVAVKEEPRGPEGSRAASRG
.: . :: :: .. :: ..: ::: .: :. . . :
NP_001 RLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPG-FEPADCKRKEEAGAPGGGAGMAAG
130 140 150 160 170
140 150 160 170 180 190
pF1KB8 SYNPLQ----YQVAHCGQT-AMHLPPTLAAPGQPLRVLKAPLATAAPPCSPLL-KAPSPA
:. ::.. :.. .. . . :: : .: . ::: . ::.:.
NP_001 FPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTP-----SPADAKAPPTACYAGAAPAPS
180 190 200 210 220 230
200 210 220 230 240 250
pF1KB8 GPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRV
:.::.:.: : ::..::::::::::::::::: : ::::.:::: ::::::...:
NP_001 QVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKV
240 250 260 270 280 290
260 270 280
pF1KB8 EQLTQELDTLRNLFRQIPEAANLIKGVGGCS
:::..::.::::::.:.:: :. . : :
NP_001 EQLSRELSTLRNLFKQLPEP--LLASSGHC
300 310 320
>>NP_005185 (OMIM: 189965) CCAAT/enhancer-binding protei (345 aa)
initn: 464 init1: 362 opt: 438 Z-score: 292.1 bits: 62.2 E(85289): 1.6e-09
Smith-Waterman score: 478; 37.1% identity (55.3% similar) in 313 aa overlap (13-280:41-345)
10 20 30
pF1KB8 MSHGTYYECEPRGGQQ-PLEFSGGRAGP----GELGDMCEHE
::. : ..: :: ::::.. .::
NP_005 CLPLPPPPPAFKSMEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPAGELGSIGDHE
20 30 40 50 60 70
40 50 60 70 80
pF1KB8 ASIDLSAYIES-GEEQ-----LLSDLF-AVKPAPE-ARGLKGPGTPAFPHYLPPD-----
.::.: :.: : : .: : :. ::: : . .: . . :
NP_005 RAIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSDLFSDDYGGKN
80 90 100 110 120 130
90 100 110 120
pF1KB8 ---PRPFAYPP-HTFGPDRKALGPGIYSS-----------------PGSYDPRAVAVKEE
: ..: .: . :: :: .. :: ..: :::
NP_005 CKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPG-FEPADCKRKEE
140 150 160 170 180
130 140 150 160 170
pF1KB8 PRGPEGSRAASRGSYNPLQ----YQVAHCGQT-AMHLPPTLAAPGQPLRVLKAPLATAAP
.: :. . . : :. ::.. :.. .. . . :: : .: . ::
NP_005 AGAPGGGAGMAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTP-----SPADAKAP
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB8 PCSPLL-KAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVL
: . ::.:. :.::.:.: : ::..::::::::::::::::: : ::::.:::
NP_005 PTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVL
250 260 270 280 290 300
240 250 260 270 280
pF1KB8 EYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
: ::::::...::::..::.::::::.:.:: :. . : :
NP_005 ELTAENERLQKKVEQLSRELSTLRNLFKQLPEP--LLASSGHC
310 320 330 340
>>NP_001272758 (OMIM: 116897,601626) CCAAT/enhancer-bind (239 aa)
initn: 491 init1: 352 opt: 412 Z-score: 278.1 bits: 59.1 E(85289): 9.4e-09
Smith-Waterman score: 486; 44.3% identity (64.3% similar) in 230 aa overlap (69-281:20-239)
40 50 60 70 80 90
pF1KB8 SIDLSAYIESGEEQLLSDLFAVKPAPEARGLKGPGTPAFPHYLPPDPRPFAYPPHTFGPD
: : : . . : ::.. . :
NP_001 MPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREED
10 20 30 40
100 110 120 130 140 150
pF1KB8 R-KALG-PGIYSSPGSYDPRAVAVKEEPRGPEGSRAASRGSYNPLQYQVAHCGQTAMHLP
. : :. :.. : . : . .:. : . :: . ::.:.::::::.:::
NP_001 EAKQLALAGLF--PYQPPPPPPPSHPHPHPPPAHLAAPH-----LQFQIAHCGQTTMHLQ
50 60 70 80 90 100
160 170 180 190 200
pF1KB8 PTLAAPGQPLRVLK---APLATAA--P-PCS---------PLLKAPSPAGPLHKGKKAVN
: .: : : . :: :: : : : : :.: . .: :.::.:.
NP_001 PGHPTP-PPTPVPSPHPAPALGAAGLPGPGSALKGLGAAHPDLRASGGSGA-GKAKKSVD
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB8 KDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELDTLR
:.: :::.:::::::::::::::::.: .:::::::: ..:.:::.:::::..::::::
NP_001 KNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLR
170 180 190 200 210 220
270 280
pF1KB8 NLFRQIPEAANLIKGVGGCS
..:::.::.. :.:..:.:.
NP_001 GIFRQLPESS-LVKAMGNCA
230
>>NP_001274364 (OMIM: 116897,601626) CCAAT/enhancer-bind (344 aa)
initn: 571 init1: 352 opt: 412 Z-score: 276.1 bits: 59.2 E(85289): 1.2e-08
Smith-Waterman score: 569; 41.5% identity (60.1% similar) in 318 aa overlap (25-281:33-344)
10 20 30 40 50
pF1KB8 MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESG--EEQ
:.: :: .::::.:::.::::. . ...
NP_001 SHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDE
10 20 30 40 50 60
60 70 80 90
pF1KB8 LLSDLFA-------VKPA--PEARGLKG----PGTPAFPH--YLPPDPRPFAYPPHTFGP
.:.::: .: : : . : : ::.:: : .: . :: .:
NP_001 FLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHG---PPPGYGC
70 80 90 100 110
100 110 120 130 140
pF1KB8 DRKALGPG----IYSSPGSYDPRAVAVKEEPRGP-EGSRAASRG--SYNP----------
. : .: :. : ...:.::: :... : : :.:
NP_001 AAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPH
120 130 140 150 160 170
150 160 170 180
pF1KB8 ------------LQYQVAHCGQTAMHLPPTLAAPGQPLRVLK---APLATAA--P-PCS-
::.:.::::::.::: : .: : : . :: :: : : :
NP_001 PHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTP-PPTPVPSPHPAPALGAAGLPGPGSA
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 --------PLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQ
: :.: . .: :.::.:.:.: :::.:::::::::::::::::.: .:::
NP_001 LKGLGAAHPDLRASGGSGA-GKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQ
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 QKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
::::: ..:.:::.:::::..::::::..:::.::.. :.:..:.:.
NP_001 QKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESS-LVKAMGNCA
300 310 320 330 340
>>NP_004355 (OMIM: 116897,601626) CCAAT/enhancer-binding (358 aa)
initn: 571 init1: 352 opt: 412 Z-score: 275.9 bits: 59.2 E(85289): 1.3e-08
Smith-Waterman score: 569; 41.5% identity (60.1% similar) in 318 aa overlap (25-281:47-358)
10 20 30 40 50
pF1KB8 MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESG--EEQ
:.: :: .::::.:::.::::. . ...
NP_004 SHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDE
20 30 40 50 60 70
60 70 80 90
pF1KB8 LLSDLFA-------VKPA--PEARGLKG----PGTPAFPH--YLPPDPRPFAYPPHTFGP
.:.::: .: : : . : : ::.:: : .: . :: .:
NP_004 FLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHG---PPPGYGC
80 90 100 110 120 130
100 110 120 130 140
pF1KB8 DRKALGPG----IYSSPGSYDPRAVAVKEEPRGP-EGSRAASRG--SYNP----------
. : .: :. : ...:.::: :... : : :.:
NP_004 AAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPH
140 150 160 170 180 190
150 160 170 180
pF1KB8 ------------LQYQVAHCGQTAMHLPPTLAAPGQPLRVLK---APLATAA--P-PCS-
::.:.::::::.::: : .: : : . :: :: : : :
NP_004 PHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTP-PPTPVPSPHPAPALGAAGLPGPGSA
200 210 220 230 240 250
190 200 210 220 230
pF1KB8 --------PLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQ
: :.: . .: :.::.:.:.: :::.:::::::::::::::::.: .:::
NP_004 LKGLGAAHPDLRASGGSGA-GKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQ
260 270 280 290 300 310
240 250 260 270 280
pF1KB8 QKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
::::: ..:.:::.:::::..::::::..:::.::.. :.:..:.:.
NP_004 QKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESS-LVKAMGNCA
320 330 340 350
>>NP_001274353 (OMIM: 116897,601626) CCAAT/enhancer-bind (393 aa)
initn: 571 init1: 352 opt: 412 Z-score: 275.3 bits: 59.3 E(85289): 1.3e-08
Smith-Waterman score: 569; 41.5% identity (60.1% similar) in 318 aa overlap (25-281:82-393)
10 20 30 40 50
pF1KB8 MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESG--EEQ
:.: :: .::::.:::.::::. . ...
NP_001 SHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDE
60 70 80 90 100 110
60 70 80 90
pF1KB8 LLSDLFA-------VKPA--PEARGLKG----PGTPAFPH--YLPPDPRPFAYPPHTFGP
.:.::: .: : : . : : ::.:: : .: . :: .:
NP_001 FLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHG---PPPGYGC
120 130 140 150 160
100 110 120 130 140
pF1KB8 DRKALGPG----IYSSPGSYDPRAVAVKEEPRGP-EGSRAASRG--SYNP----------
. : .: :. : ...:.::: :... : : :.:
NP_001 AAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPH
170 180 190 200 210 220
150 160 170 180
pF1KB8 ------------LQYQVAHCGQTAMHLPPTLAAPGQPLRVLK---APLATAA--P-PCS-
::.:.::::::.::: : .: : : . :: :: : : :
NP_001 PHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTP-PPTPVPSPHPAPALGAAGLPGPGSA
230 240 250 260 270 280
190 200 210 220 230
pF1KB8 --------PLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQ
: :.: . .: :.::.:.:.: :::.:::::::::::::::::.: .:::
NP_001 LKGLGAAHPDLRASGGSGA-GKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQ
290 300 310 320 330 340
240 250 260 270 280
pF1KB8 QKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
::::: ..:.:::.:::::..::::::..:::.::.. :.:..:.:.
NP_001 QKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESS-LVKAMGNCA
350 360 370 380 390
>>NP_001272808 (OMIM: 189965) CCAAT/enhancer-binding pro (147 aa)
initn: 362 init1: 362 opt: 400 Z-score: 273.5 bits: 57.5 E(85289): 1.7e-08
Smith-Waterman score: 400; 50.7% identity (71.1% similar) in 142 aa overlap (141-280:13-147)
120 130 140 150 160
pF1KB8 GSYDPRAVAVKEEPRGPEGSRAASRGSYNPLQYQVAHCGQT-AMHLPPTLAAPGQPLRVL
: ::.. :.. .. . . :: :
NP_001 MAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTP----
10 20 30
170 180 190 200 210 220
pF1KB8 KAPLATAAPPCSPLL-KAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRR
.: . ::: . ::.:. :.::.:.: : ::..::::::::::::::::: :
NP_001 -SPADAKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMR
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB8 ILETQQKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
::::.:::: ::::::...::::..::.::::::.:.:: :. . : :
NP_001 NLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEP--LLASSGHC
100 110 120 130 140
>>NP_005186 (OMIM: 116898) CCAAT/enhancer-binding protei (269 aa)
initn: 424 init1: 318 opt: 387 Z-score: 262.1 bits: 56.3 E(85289): 7.4e-08
Smith-Waterman score: 444; 39.5% identity (55.5% similar) in 299 aa overlap (12-280:13-268)
10 20 30 40
pF1KB8 MSHGTYYECEPRGGQQPLE----FSGGRAG-------PGELGD-------MCEHEASID
::. : : . :::: :: ::. : . :..::
NP_005 MSAALFSLDGPARGAPWPAEPAPFYEPGRAGKPGRGAEPGALGEPGAAAPAMYDDESAID
10 20 30 40 50 60
50 60 70 80 90
pF1KB8 LSAYIESG---------EEQLLSDLFAVKPAPEARGLKGPGTPAFPHYLPPDPRPFAYPP
.::::.: ...:..::: . . : :: . :: : : :
NP_005 FSAYIDSMAAVPTLELCHDELFADLFN---SNHKAGGAGPL-----ELLPGGP---ARP-
70 80 90 100
100 110 120 130 140 150
pF1KB8 HTFGPDRKALGPGIYSSPGSYDPRAVAVKEEPRGPEGSRAASRGSYNPLQYQVAHCGQTA
:::: :.. :: .:.:: .:. . :: : : :: :.::.
NP_005 ---------LGPG----PAA--PRL--LKREPDWGDGD---APGSLLPAQ--VAACAQTV
110 120 130 140
160 170 180 190 200 210
pF1KB8 MHLPPTLAAPGQPLRVLKAPLATAAPP-CSP-LLKAPSPAGPLHKGKKAVNKDSLEYRLR
. .::: ::: .: .. :: :: ::.:: ::.. .. : ::: :
NP_005 V----SLAAAGQP-----TPPTSPEPPRSSPRQTPAPGPAREKSAGKRGPDRGSPEYRQR
150 160 170 180 190
220 230 240 250 260 270
pF1KB8 RERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEA
:::::::::::::::::: : :::..: ::::.:..::::::..: ::..:.:.:
NP_005 RERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKLHQRVEQLTRDLAGLRQFFKQLPSP
200 210 220 230 240 250
280
pF1KB8 ANL-IKGVGGCS
: :.. :
NP_005 PFLPAAGTADCR
260
281 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:03:03 2016 done: Sat Nov 5 20:03:04 2016
Total Scan time: 7.080 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]