Result of FASTA (omim) for
pF1KB8925
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8925, 273 aa
1>>>pF1KB8925 273 - 273 aa - 273 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2930+/-0.000284; mu= 7.5574+/- 0.018
mean_var=155.8701+/-32.687, 0's: 0 Z-trim(122.4): 237 B-trim: 1982 in 1/50
Lambda= 0.102729
statistics sampled from 40139 (40440) to 40139 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.474), width: 16
Scan time: 6.870
The best scores are: opt bits E(85289)
NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 ( 273) 1845 284.4 1.6e-76
XP_006723629 (OMIM: 604612) PREDICTED: homeobox pr ( 202) 1270 199.0 5.8e-51
NP_001129743 (OMIM: 217095,611770) homeobox protei ( 301) 506 85.9 9.4e-17
NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 ( 364) 481 82.3 1.4e-15
NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 466 80.0 6.1e-15
NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 ( 239) 436 75.5 1.1e-13
NP_003308 (OMIM: 118700,188550,600635,610978) home ( 371) 368 65.6 1.6e-10
NP_001073136 (OMIM: 118700,188550,600635,610978) h ( 401) 368 65.6 1.7e-10
NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 ( 354) 365 65.1 2.1e-10
NP_001180 (OMIM: 602183,613330) homeobox protein N ( 333) 305 56.2 9.5e-08
NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 287 53.5 6.2e-07
NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 273 51.5 2.7e-06
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 272 51.4 3.5e-06
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 272 51.4 3.5e-06
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 272 51.4 3.5e-06
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 272 51.4 3.5e-06
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 272 51.4 3.5e-06
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 272 51.4 3.5e-06
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 272 51.4 3.5e-06
XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 257 49.0 1.1e-05
NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 257 49.0 1.1e-05
NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 249 47.6 1.7e-05
NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 251 48.1 1.9e-05
NP_001476 (OMIM: 601135) homeobox protein GBX-2 is ( 348) 247 47.6 3.8e-05
NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 244 47.1 4.4e-05
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 245 47.4 5.5e-05
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 245 47.4 5.5e-05
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 245 47.4 5.5e-05
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 245 47.4 5.5e-05
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 245 47.4 5.5e-05
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 245 47.4 5.5e-05
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 245 47.4 5.5e-05
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 245 47.4 5.5e-05
NP_001091639 (OMIM: 611074) brain-specific homeobo ( 233) 240 46.4 5.7e-05
NP_835221 (OMIM: 600029) homeobox protein DLX-1 is ( 255) 240 46.5 6.1e-05
NP_005213 (OMIM: 600030) homeobox protein DLX-6 [H ( 293) 239 46.4 7.6e-05
NP_612138 (OMIM: 601911,616788) homeobox protein D ( 240) 236 45.8 8.9e-05
NP_004396 (OMIM: 126255) homeobox protein DLX-2 [H ( 328) 235 45.8 0.00012
NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 232 45.3 0.00014
NP_005212 (OMIM: 220600,600028) homeobox protein D ( 289) 233 45.5 0.00014
XP_016867454 (OMIM: 603354) PREDICTED: homeobox pr ( 203) 230 44.9 0.00014
XP_016867453 (OMIM: 603354) PREDICTED: homeobox pr ( 204) 230 44.9 0.00015
XP_011541345 (OMIM: 604823) PREDICTED: homeobox pr ( 233) 229 44.8 0.00018
NP_003649 (OMIM: 604823) homeobox protein BarH-lik ( 279) 229 44.9 0.0002
NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 228 44.7 0.00022
NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 230 45.1 0.00022
NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 228 44.7 0.00024
NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 228 44.8 0.00026
NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313) 227 44.6 0.00027
NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 226 44.6 0.00037
>>NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 [Hom (273 aa)
initn: 1845 init1: 1845 opt: 1845 Z-score: 1494.8 bits: 284.4 E(85289): 1.6e-76
Smith-Waterman score: 1845; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273)
10 20 30 40 50 60
pF1KB8 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQ
190 200 210 220 230 240
250 260 270
pF1KB8 SLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW
:::::::::::::::::::::::::::::::::
NP_002 SLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW
250 260 270
>>XP_006723629 (OMIM: 604612) PREDICTED: homeobox protei (202 aa)
initn: 1270 init1: 1270 opt: 1270 Z-score: 1036.0 bits: 199.0 E(85289): 5.8e-51
Smith-Waterman score: 1270; 100.0% identity (100.0% similar) in 187 aa overlap (87-273:16-202)
60 70 80 90 100 110
pF1KB8 QSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDK
::::::::::::::::::::::::::::::
XP_006 MIFSATSPPKFSPTLLHGLAAGAPPQDSSSKSPEPSADESPDNDK
10 20 30 40
120 130 140 150 160 170
pF1KB8 ETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWF
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB8 QNHRYKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNHRYKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSA
110 120 130 140 150 160
240 250 260 270
pF1KB8 YSAQSLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW
:::::::::::::::::::::::::::::::::::::
XP_006 YSAQSLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW
170 180 190 200
>>NP_001129743 (OMIM: 217095,611770) homeobox protein Nk (301 aa)
initn: 484 init1: 349 opt: 506 Z-score: 421.7 bits: 85.9 E(85289): 9.4e-17
Smith-Waterman score: 509; 40.7% identity (61.1% similar) in 285 aa overlap (6-268:7-276)
10 20 30 40
pF1KB8 MSLTNTKTGFSVKDILDLP-----DTNDEEGSVAEGPEE--------ENEGPEPAKRAG
:.: ::::::: : . . . : ..::. : .: : . .:
NP_001 MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 PLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEP
:. ::. : : .: . : ::. .: : .... ::
NP_001 GGGDRKLDG--SEPPGGPCEAVLEMDAERMGEPQPGLN--------AASPLGGGTRVPER
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 SADESPDNDKETPGGGGDAGKKRKRR---VLFSKAQTYELERRFRQQRYLSAPEREHLAS
.. .: :. . :: .. : :.:: ::::.::. :::::.:::::::::::::::
NP_001 GVGNSGDSVR---GGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLAS
120 130 140 150 160
170 180 190 200 210 220
pF1KB8 LIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLP-SPRRVAVPVLVRDGKPCHALKAQD
..:: :::::::::.::: :: : .:..:.. : .:::::::::::::::: .
NP_001 ALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGA
170 180 190 200 210 220
230 240 250 260 270
pF1KB8 LA-AATFQAGI-PFSAYSAQSLQHMQYNAQYSS--ASTPQYPTAH-PLVQAQQWTW
: . ..:.. :.: :.. : :.: :.. :..:. :. : ::..:
NP_001 PAFPSPYSAAVSPYSCYGGYS--GAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNA
230 240 250 260 270 280
NP_001 TPQGHLAATLQGVRAW
290 300
>>NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 [Hom (364 aa)
initn: 477 init1: 334 opt: 481 Z-score: 400.6 bits: 82.3 E(85289): 1.4e-15
Smith-Waterman score: 485; 40.1% identity (61.3% similar) in 279 aa overlap (6-255:8-275)
10 20 30
pF1KB8 MSLTNTKTGFSVKDILDLPDTN----------DEEG---------SVAEGPEEENEGP
:.: :::::::.: . . : : ..::: . . :
NP_660 MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 EPAKRAGPLGQGALDAVQSLPLKNPFYDSSDNP--YTRWL---ASTEGLQYSLHGLAAGA
: . : :. ..:: . ::. : :.. . . .: .. . ..
NP_660 EDEEDEGE----KLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRD
70 80 90 100 110
100 110 120 130 140 150
pF1KB8 PPQDSSS--KSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRY
: : . :: : ..: . ...: : ..:: :::::.::..::::::.::::
NP_660 RSQKSCQLKKSLETAGDCKAAEESERP----KPRSRRKPRVLFSQAQVFELERRFKQQRY
120 130 140 150 160 170
160 170 180 190 200
pF1KB8 LSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEV---TPLPSPRRVAVPVLV
::::::::::: ..:: :::::::::.::: :: : .:..:. .: : ::::::::::
NP_660 LSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLV
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 RDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQYPTAHPLVQAQ
:::::: . .:: .: ...: :::: .:. . :. . ..:.
NP_660 RDGKPCVTPSAQAYGAP-YSVGA--SAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSS
240 250 260 270 280
270
pF1KB8 QWTW
NP_660 SYGCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSGGSAQPLHQGTAA
290 300 310 320 330 340
>>NP_004378 (OMIM: 108900,187500,217095,225250,600584,61 (324 aa)
initn: 383 init1: 348 opt: 466 Z-score: 389.3 bits: 80.0 E(85289): 6.1e-15
Smith-Waterman score: 466; 37.2% identity (60.3% similar) in 282 aa overlap (6-264:8-275)
10 20 30 40
pF1KB8 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPE-----EENEGP--------EPAKRA
: : :::::::.: .... :.: . : : . .: .: :
NP_004 MFPSPALTPTPFSVKDILNL---EQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYA
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 GPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPE
:: . :. .:: . .: : . . .. . : .: ... :
NP_004 GPEA-----AAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 PSADESPDNDKETPGGGGD---AGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLA
: .. . ..: . ... : ..:: :::::.::.:::::::.::::::::::..::
NP_004 LCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLA
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 SLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSP-----RRVAVPVLVRDGKPCHA
:...:: :::::::::.::: :: : .. .:.. :: : ::.:::::::::::: .
NP_004 SVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLG
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 LKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQYP--TAHPLVQAQQWTW
.: : .. .:. .:.: . : . ..: .: : .:.:
NP_004 DSAP--YAPAYGVGLNPYGYNA----YPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATA
240 250 260 270 280
NP_004 AANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
290 300 310 320
>>NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 [Hom (239 aa)
initn: 557 init1: 388 opt: 436 Z-score: 367.0 bits: 75.5 E(85289): 1.1e-13
Smith-Waterman score: 526; 45.8% identity (64.0% similar) in 236 aa overlap (54-273:21-239)
30 40 50 60 70 80
pF1KB8 EEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLPLKNPFYDSSD-NPYTRWLASTEG
:: : :: ..: . . .: . :: : .:
NP_055 MATSGRLSFTVRSLLDLPEQDA-QHLPRREPEPRAPQPDPCAAWLDSERG
10 20 30 40
90 100 110 120 130 140
pF1KB8 LQYSLHGLAAGAPPQDSSS-KSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTY
.: : .: :: .. :.... :. .::. :: :..:::::::::::
NP_055 -HY---------PSSDESSLETSPPDSSQRPSARPASPGS--DAEKRKKRRVLFSKAQTL
50 60 70 80 90
150 160 170 180 190
pF1KB8 ELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPS--
::::::::::::::::::.::::.:::::::::::::::::.::::: . : : .
NP_055 ELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASA
100 110 120 130 140 150
200 210 220 230 240
pF1KB8 -----P---RRVAVPVLVRDGKPCHALKAQDL--AAATFQAGIPFSAYSAQSLQHMQYNA
: :::.::::::::.:: . . .. ::: . : : .: : : : :
NP_055 ELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAPPAA--ACPLP--GYPA
160 170 180 190 200 210
250 260 270
pF1KB8 QYSSASTPQYPTAHPLVQAQ--QWTW
... .:. . :.. .:.:
NP_055 FGPGSALGLFPAYQHLASPALVSWNW
220 230
>>NP_003308 (OMIM: 118700,188550,600635,610978) homeobox (371 aa)
initn: 491 init1: 357 opt: 368 Z-score: 310.0 bits: 65.6 E(85289): 1.6e-10
Smith-Waterman score: 456; 38.9% identity (59.1% similar) in 257 aa overlap (26-255:62-303)
10 20 30 40 50
pF1KB8 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEG-PEPAKRA-GPLGQGAL
:.:. . . : :. .. : : .: :
NP_003 GGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB8 DAVQSLPLKNPFYDSSDNPYTR--WLASTEGLQY-SLHGLAAGAPPQDSSSKSPEPSADE
.. :: :. :. : . : ... .. .. . . : .. :. . : .
NP_003 GNMSELP---PYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGD
100 110 120 130 140
120 130 140 150 160 170
pF1KB8 SPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPT
: : .. .::::::::.::.:::::::.::.::::::::::::.:.::::
NP_003 VSKNMAPLP-----SAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPT
150 160 170 180 190 200
180 190 200
pF1KB8 QVKIWFQNHRYKMKRARAEKGMEV--------------TPLP--------SPRRVAVPVL
::::::::::::::: .:. . : : ::::::::::
NP_003 QVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVL
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB8 VRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQYPTAHPLVQA
:.:::::.: : .::..:. .. :. ::. :: ..:.
NP_003 VKDGKPCQA-GAPAPGAASLQG------HAQQQAQHQAQAAQAAAAAISVGSGGAGLGAH
270 280 290 300 310
270
pF1KB8 QQWTW
NP_003 PGHQPGSAGQSPDLAHHAASPAALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW
320 330 340 350 360 370
>>NP_001073136 (OMIM: 118700,188550,600635,610978) homeo (401 aa)
initn: 491 init1: 357 opt: 368 Z-score: 309.5 bits: 65.6 E(85289): 1.7e-10
Smith-Waterman score: 456; 38.9% identity (59.1% similar) in 257 aa overlap (26-255:92-333)
10 20 30 40 50
pF1KB8 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEG-PEPAKRA-GPLGQGAL
:.:. . . : :. .. : : .: :
NP_001 GGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNL
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB8 DAVQSLPLKNPFYDSSDNPYTR--WLASTEGLQY-SLHGLAAGAPPQDSSSKSPEPSADE
.. :: :. :. : . : ... .. .. . . : .. :. . : .
NP_001 GNMSELP---PYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGD
130 140 150 160 170
120 130 140 150 160 170
pF1KB8 SPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPT
: : .. .::::::::.::.:::::::.::.::::::::::::.:.::::
NP_001 VSKNMAPLP-----SAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPT
180 190 200 210 220 230
180 190 200
pF1KB8 QVKIWFQNHRYKMKRARAEKGMEV--------------TPLP--------SPRRVAVPVL
::::::::::::::: .:. . : : ::::::::::
NP_001 QVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVL
240 250 260 270 280 290
210 220 230 240 250 260
pF1KB8 VRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQYPTAHPLVQA
:.:::::.: : .::..:. .. :. ::. :: ..:.
NP_001 VKDGKPCQA-GAPAPGAASLQG------HAQQQAQHQAQAAQAAAAAISVGSGGAGLGAH
300 310 320 330 340
270
pF1KB8 QQWTW
NP_001 PGHQPGSAGQSPDLAHHAASPAALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW
350 360 370 380 390 400
>>NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 [Hom (354 aa)
initn: 536 init1: 357 opt: 365 Z-score: 307.8 bits: 65.1 E(85289): 2.1e-10
Smith-Waterman score: 474; 46.9% identity (63.0% similar) in 192 aa overlap (36-216:117-288)
10 20 30 40 50 60
pF1KB8 TKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLPLKNPF
: : :: : : .: . : .:
NP_149 AAAAATYHMPPGVSQFPHGAMGSYCNGGLGNMGELPAYTDGMRGGAATGWYGANP--DPR
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB8 YDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDA
:.: .:... . :.. . : .: ...:: : .... :
NP_149 YSS----ISRFMGPSAGVNVAGMGSLTGIA---DAAKSLGP-----------LHAAAAAA
150 160 170 180
130 140 150 160 170 180
pF1KB8 GKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR
. .::::::::.::.:::::::.::.::::::::::::.:.:::::::::::::::::::
NP_149 APRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR
190 200 210 220 230 240
190 200 210 220 230
pF1KB8 ARAEK-----------GMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPF
.: : : ::::::::::::.:::::.
NP_149 QAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAP
250 260 270 280 290 300
240 250 260 270
pF1KB8 SAYSAQSLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW
NP_149 TPAPELEELSPSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW
310 320 330 340 350
>>NP_001180 (OMIM: 602183,613330) homeobox protein Nkx-3 (333 aa)
initn: 346 init1: 260 opt: 305 Z-score: 260.1 bits: 56.2 E(85289): 9.5e-08
Smith-Waterman score: 311; 36.5% identity (53.2% similar) in 233 aa overlap (21-213:77-290)
10 20 30 40
pF1KB8 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPE---------EENEGPEP
: : .::.:: ::::. .
NP_001 PAVCCWRLFGERDAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRR
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB8 AKRA-GPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSS
: : : : : :: : .: . ::... :. ::: ...:
NP_001 CADARGASGAGL--AGGSLSLGQPVCE---------LAASKDLEEE----AAG---RSDS
110 120 130 140
110 120 130
pF1KB8 SKSPEPSADESP--DNDKETP------------GGGGDAG----------------KKRK
: :.:.:: ..: : :::: .: .:..
NP_001 EMSASVSGDRSPRTEDDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKR
150 160 170 180 190 200
140 150 160 170 180 190
pF1KB8 RRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEK
:. ::.::..:::::: .:::::.::: ::. ..:: :::::::::.::: :: .
NP_001 SRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAA
210 220 230 240 250 260
200 210 220 230 240 250
pF1KB8 GMEVTPLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQ
. .. :. ..::: ::::: .
NP_001 DL-LASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYYYPYYCLPGWALSTCA
270 280 290 300 310 320
273 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:31:11 2016 done: Fri Nov 4 16:31:13 2016
Total Scan time: 6.870 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]