Result of FASTA (ccds) for
pF1KB8908
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8908, 242 aa
1>>>pF1KB8908 242 - 242 aa - 242 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3652+/-0.00077; mu= 6.0974+/- 0.047
mean_var=161.6228+/-32.779, 0's: 0 Z-trim(114.0): 159 B-trim: 0 in 0/51
Lambda= 0.100884
statistics sampled from 14405 (14582) to 14405 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.448), width: 16
Scan time: 2.190
The best scores are: opt bits E(32554)
CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 ( 242) 1678 255.3 2.7e-68
CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 ( 243) 997 156.2 1.9e-38
CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 ( 289) 796 127.0 1.4e-29
CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 ( 290) 784 125.2 4.6e-29
CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 ( 106) 536 88.8 1.6e-18
CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 ( 224) 452 76.8 1.3e-14
CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 ( 230) 435 74.4 7.5e-14
CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 ( 217) 417 71.7 4.4e-13
CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 ( 235) 417 71.7 4.7e-13
CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 ( 153) 410 70.6 6.9e-13
CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 ( 233) 408 70.4 1.2e-12
>>CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 (242 aa)
initn: 1678 init1: 1678 opt: 1678 Z-score: 1339.6 bits: 255.3 E(32554): 2.7e-68
Smith-Waterman score: 1678; 100.0% identity (100.0% similar) in 242 aa overlap (1-242:1-242)
10 20 30 40 50 60
pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 EVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN
190 200 210 220 230 240
pF1KB8 KD
::
CCDS88 KD
>>CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 (243 aa)
initn: 947 init1: 645 opt: 997 Z-score: 803.9 bits: 156.2 E(32554): 1.9e-38
Smith-Waterman score: 997; 62.0% identity (81.6% similar) in 245 aa overlap (1-241:1-239)
10 20 30 40 50
pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP--GGSAPGFQHASHHVQD
::::::: ::::::.::::.: :::: : :..: ..:::: ::: ::: :. .:.
CCDS11 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGS---FQHPSQ-IQE
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 FFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSA
:.: : :..:.. ::::::...:::: ..::::. : ::::.::: . ..::: ::: .:
CCDS11 FYH-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 NTNSSEGQGHLNQNSSPSLMFPWMRPHAP-GRRSGRQTYSRYQTLELEKEFLFNPYLTRK
.. .: .:. ::. .::::::.: ::: ::::::::::::::::::::::::::
CCDS11 ASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEE
:::::::::::::::::::::::::::::::::::.:... ..:..:.. :. . .:
CCDS11 RRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADE
180 190 200 210 220 230
240
pF1KB8 KEENKD
. .:
CCDS11 GDAQKGDKK
240
>>CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 (289 aa)
initn: 893 init1: 601 opt: 796 Z-score: 644.8 bits: 127.0 E(32554): 1.4e-29
Smith-Waterman score: 866; 54.3% identity (69.1% similar) in 265 aa overlap (15-238:23-285)
10 20 30 40
pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP----GGSAPG
:::...:.::::.: :: :: . . :.:: :
CCDS56 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG
10 20 30 40 50 60
50 60 70
pF1KB8 FQHASHHV----------------------QDFFHHGTSGISNSGYQQNP----------
: :: .. :..:: : .: ..:: :
CCDS56 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPG-GGSPAAAYQAAPPPPPHPPPPP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 ----CS-LSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ
:. ..:::. .:::::. : :: .. .:::: .:::::::::.. : .: ::::
CCDS56 PPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSG-NIGEDPDHLNQ
120 130 140 150 160 170
140 150 160 170 180 190
pF1KB8 NSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER
.:::: :::::::.::::: :::::::.:::::::::::::::::::::::::::.::::
CCDS56 SSSPSQMFPWMRPQAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTER
180 190 200 210 220 230
200 210 220 230 240
pF1KB8 QVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD
:::::::::::::::::::::.: .:.: : : .: .: ::.. :
CCDS56 QVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN
240 250 260 270 280
>>CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 (290 aa)
initn: 885 init1: 646 opt: 784 Z-score: 635.3 bits: 125.2 E(32554): 4.6e-29
Smith-Waterman score: 854; 54.1% identity (68.8% similar) in 266 aa overlap (15-238:23-286)
10 20 30 40
pF1KB8 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGP----GGSAPG
:::...:.::::.: :: :: . . :.:: :
CCDS22 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG
10 20 30 40 50 60
50 60 70
pF1KB8 FQHASHHV----------------------QDFFHHGTSGISNSGYQQNP----------
: :: .. :..:: : .: ..:: :
CCDS22 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPG-GGSPAAAYQAAPPPPPHPPPPP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 ----CS-LSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ
:. ..:::. .:::::. : :: .. .:::: .:::::::::.. : .: ::::
CCDS22 PPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSG-NIGEDPDHLNQ
120 130 140 150 160 170
140 150 160 170 180 190
pF1KB8 NSSPSLMFPWMRPHA-PGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTE
.:::: :::::::.: :::: :::::::.:::::::::::::::::::::::::::.:::
CCDS22 SSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTE
180 190 200 210 220 230
200 210 220 230 240
pF1KB8 RQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD
::::::::::::::::::::::.: .:.: : : .: .: ::.. :
CCDS22 RQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAEGLTN
240 250 260 270 280 290
>>CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 (106 aa)
initn: 540 init1: 483 opt: 536 Z-score: 446.1 bits: 88.8 E(32554): 1.6e-18
Smith-Waterman score: 536; 79.4% identity (89.2% similar) in 102 aa overlap (138-238:1-102)
110 120 130 140 150 160
pF1KB8 VVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHA-PGRRSGRQTYSRYQTLELEK
:::::::.: :::: :::::::.:::::::
CCDS56 MFPWMRPQAAPGRRRGRQTYSRFQTLELEK
10 20 30
170 180 190 200 210 220
pF1KB8 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEG
::::::::::::::::::::.:::::::::::::::::::::::::.: .:.: : :
CCDS56 EFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETK
40 50 60 70 80 90
230 240
pF1KB8 NEEEEKEEEEKEENKD
.: .: ::.. :
CCDS56 KEAQELEEDRAEGLTN
100
>>CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 (224 aa)
initn: 443 init1: 342 opt: 452 Z-score: 375.7 bits: 76.8 E(32554): 1.3e-14
Smith-Waterman score: 452; 39.8% identity (60.2% similar) in 241 aa overlap (1-224:1-224)
10 20 30 40 50
pF1KB8 MSSYFVNPLFSKYKAG--ESL--EPAYYDCRFPQSVGRSHALVYGPG-GSAPGFQHASHH
::::::: : :. ::. . :. . . . : . :::: :. :: .:..
CCDS11 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPL-RHYPAPYGPGPGQDKGFATSSYY
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 VQDFFHHGTSGISNSGY-QQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDC
...:: . ::. .: : :: : .: ::... :
CCDS11 PP----------AGGGYGRAAPCD---YGPAPAFY-REKESACALSGADEQPPFHPEPRK
60 70 80 90 100
120 130 140 150 160
pF1KB8 KSSANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGRRSGRQTYSRYQTLELEK
.. :. .: :. . .. :.: ..:::. .:. : :::::.:::::::::
CCDS11 SDCAQDKSVFGETEEQKCSTP--VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEK
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB8 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN---NKDKLPGARDEEKVE
:: .: ::::.::::..::: :::::.::::::::::::::. . ..: . ..:::
CCDS11 EFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQA
170 180 190 200 210 220
230 240
pF1KB8 EEGNEEEEKEEEEKEENKD
:
CCDS11 E
>>CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 (230 aa)
initn: 537 init1: 389 opt: 435 Z-score: 362.1 bits: 74.4 E(32554): 7.5e-14
Smith-Waterman score: 508; 43.9% identity (61.3% similar) in 253 aa overlap (2-236:3-230)
10 20 30 40 50
pF1KB8 MSSYFVNPLFSKYKAGESL----EPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHH
:::.:: ::::: :: :: ::. .: : . :: :: :..: ::
CCDS54 MSSSYYVNALFSKYTAGASLFQNAEPT--SCSFAPNSQRSG---YGAGAGA----FAST-
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 VQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCK
: ... :: :.: . : .: .. :: :: : :. .. . :
CCDS54 VPGLYN------VNSPLYQSPFA-SGYGLGADAYG--NLPCASY--DQNIPGLCS--DLA
60 70 80 90
120 130 140 150 160 170
pF1KB8 SSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLT
..: ...:: : ... . .:::: .: :. :::::.::::::::::: :: :::
CCDS54 KGACDKTDEGALHGAAEANFRI-YPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLT
100 110 120 130 140 150
180 190 200 210 220
pF1KB8 RKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDE--------------EK
:.::::..::: :::::.::::::::::::::. ::. : : .:
CCDS54 RRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH-KDEGPTAAAAPEGAVPSAAATAAADK
160 170 180 190 200 210
230 240
pF1KB8 VEEEGNEEEEKEEEEKEENKD
..:: ..:::..:::
CCDS54 ADEEDDDEEEEDEEE
220 230
>>CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 (217 aa)
initn: 432 init1: 382 opt: 417 Z-score: 348.3 bits: 71.7 E(32554): 4.4e-13
Smith-Waterman score: 467; 40.7% identity (61.3% similar) in 243 aa overlap (1-230:1-217)
10 20 30 40 50
pF1KB8 MSS-YFVNPLFSKYKAGESLE-----PAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASH
::: :..: ::::: :. :. : .: : .. : :: .::. .: ::
CCDS11 MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPG---YG-AGSGASFA-AS-
10 20 30 40 50
60 70 80 90 100
pF1KB8 HVQDFFHHG-------TSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEAS
.: .. : ..:. .:: .: :.. : . : .:.: :.
CCDS11 -MQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMH--CAPF-------EQNLSGVC----
60 70 80 90 100
110 120 130 140 150 160
pF1KB8 VVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKE
: ...: . . .. : .:. . .:::: . :. :::::.::::::::::
CCDS11 ----PGDSAKAAGAKEQRDSDLAAESNFRI-YPWMRSSGTDRKRGRQTYTRYQTLELEKE
110 120 130 140 150
170 180 190 200 210 220
pF1KB8 FLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGN
: .: ::::.::::..:.: :::::.::::::::::::::: : ::. ....: : .
CCDS11 FHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKEN-KTAGPGTTGQDRAEAEEE
160 170 180 190 200 210
230 240
pF1KB8 EEEEKEEEEKEENKD
:::
CCDS11 EEE
>>CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 (235 aa)
initn: 442 init1: 359 opt: 417 Z-score: 347.8 bits: 71.7 E(32554): 4.7e-13
Smith-Waterman score: 431; 36.4% identity (58.6% similar) in 261 aa overlap (1-242:1-235)
10 20 30 40 50
pF1KB8 MSSYFVNPLFSKYKAG-ESLEP-------AYYDCRFPQSVGRSHAL--VYGPGGSAPGFQ
:.:::.:: .: . :: ... : :: : .. : . : .:. .: .
CCDS88 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQEN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 HASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQ
. . . .: ::: ::.. .: ::. : . ..:..:
CCDS88 VVFSSSRGPYDYG----SNSFYQEKDMLSNC--------------RQNTLGHNTQTSIAQ
70 80 90 100
120 130 140 150 160
pF1KB8 YPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMR---PHA-----PGRRSGRQTYSRYQTL
. .: .:. ..... ..:::. :. :: ::: :::::::
CCDS88 --------DFSSEQGRTAPQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTL
110 120 130 140 150
170 180 190 200 210 220
pF1KB8 ELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENN-KDKLPGARDEEK
:::::: :: ::::.::::...:: :::::.::::::::::::::.: . : :.
CCDS88 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGAT
160 170 180 190 200 210
230 240
pF1KB8 VEEEGNEEEEKEEEEKEENKD
.. :..::..:: :.:..:.
CCDS88 ADSLGGKEEKREETEEEKQKE
220 230
>>CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 (153 aa)
initn: 398 init1: 359 opt: 410 Z-score: 344.8 bits: 70.6 E(32554): 6.9e-13
Smith-Waterman score: 410; 46.8% identity (67.9% similar) in 156 aa overlap (96-242:6-153)
70 80 90 100 110 120
pF1KB8 GISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEG
::. : . ..:..: : .: . .. .
CCDS41 MLSNCRQNTLGHNTQTSIAQ--DFSSEQGRTAPQD
10 20 30
130 140 150 160 170
pF1KB8 QGHLNQNSSPSLMFPWMR---PHA-----PGRRSGRQTYSRYQTLELEKEFLFNPYLTRK
: : ..:::. :. :: ::: ::::::::::::: :: ::::.
CCDS41 QKASIQ------IYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRR
40 50 60 70 80
180 190 200 210 220 230
pF1KB8 RRIEVSHALGLTERQVKIWFQNRRMKWKKENN-KDKLPGARDEEKVEEEGNEEEEKEEEE
::::...:: :::::.::::::::::::::.: . : :. .. :..::..:: :
CCDS41 RRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETE
90 100 110 120 130 140
240
pF1KB8 KEENKD
.:..:.
CCDS41 EEKQKE
150
242 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:26:45 2016 done: Fri Nov 4 16:26:46 2016
Total Scan time: 2.190 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]