Result of FASTA (omim) for
pF1KB8881
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8881, 179 aa
1>>>pF1KB8881 179 - 179 aa - 179 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7501+/-0.000297; mu= 11.4355+/- 0.019
mean_var=84.4993+/-17.150, 0's: 0 Z-trim(118.3): 66 B-trim: 1471 in 1/52
Lambda= 0.139524
statistics sampled from 31108 (31182) to 31108 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.366), width: 16
Scan time: 5.320
The best scores are: opt bits E(85289)
NP_003197 (OMIM: 603306) transcription factor 21 [ ( 179) 1165 243.4 1.4e-64
NP_938206 (OMIM: 603306) transcription factor 21 [ ( 179) 1165 243.4 1.4e-64
NP_005089 (OMIM: 603628) musculin [Homo sapiens] ( 206) 635 136.8 2.1e-32
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199) 237 56.7 2.6e-08
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201) 222 53.7 2.1e-07
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201) 222 53.7 2.1e-07
XP_005264216 (OMIM: 609635) PREDICTED: transcripti ( 210) 221 53.5 2.6e-07
NP_786951 (OMIM: 609635) transcription factor 23 [ ( 214) 221 53.5 2.6e-07
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 210 51.2 9.5e-07
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 210 51.2 9.5e-07
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217) 205 50.3 2.4e-06
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202) 203 49.8 3.1e-06
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202) 203 49.8 3.1e-06
NP_066279 (OMIM: 604882,610370) neurogenin-3 [Homo ( 214) 196 48.4 8.5e-06
XP_016871769 (OMIM: 604882,610370) PREDICTED: neur ( 214) 196 48.4 8.5e-06
NP_002491 (OMIM: 125853,601724,606394) neurogenic ( 356) 191 47.6 2.6e-05
XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172) 184 46.0 3.8e-05
NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172) 184 46.0 3.8e-05
XP_005268588 (OMIM: 602406) PREDICTED: heart- and ( 214) 183 45.8 5.2e-05
NP_004812 (OMIM: 602406) heart- and neural crest d ( 215) 183 45.8 5.2e-05
NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331) 184 46.2 6.4e-05
XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 184 46.2 6.4e-05
NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331) 184 46.2 6.4e-05
XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 184 46.2 6.4e-05
XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 184 46.2 6.4e-05
NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331) 184 46.2 6.4e-05
XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 184 46.2 6.4e-05
XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 184 46.2 6.4e-05
NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331) 184 46.2 6.4e-05
XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 184 46.2 6.4e-05
NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331) 184 46.2 6.4e-05
NP_006151 (OMIM: 601725) neurogenic differentiatio ( 382) 184 46.2 7.2e-05
NP_067014 (OMIM: 611635) neurogenic differentiatio ( 331) 183 46.0 7.4e-05
NP_005589 (OMIM: 162360) helix-loop-helix protein ( 133) 176 44.3 9.5e-05
NP_005163 (OMIM: 601461) protein atonal homolog 1 ( 354) 179 45.2 0.00014
NP_660161 (OMIM: 609875) protein atonal homolog 7 ( 152) 173 43.7 0.00016
NP_073565 (OMIM: 611513) neurogenic differentiatio ( 337) 176 44.6 0.0002
NP_005590 (OMIM: 162361) helix-loop-helix protein ( 135) 169 42.9 0.00025
NP_001104531 (OMIM: 162361) helix-loop-helix prote ( 135) 169 42.9 0.00025
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328) 174 44.1 0.00026
NP_076924 (OMIM: 606624) neurogenin-2 [Homo sapien ( 272) 171 43.5 0.00034
NP_061140 (OMIM: 608689) mesoderm posterior protei ( 268) 170 43.3 0.00038
NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189) 167 42.6 0.00044
NP_001004311 (OMIM: 608697,612310) factor in the g ( 219) 165 42.2 0.00065
NP_001035047 (OMIM: 277300,605195,608681) mesoderm ( 397) 165 42.4 0.0011
NP_006152 (OMIM: 601726) neurogenin-1 [Homo sapien ( 237) 161 41.4 0.0012
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206) 159 41.0 0.0014
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108) 155 40.0 0.0015
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280) 159 41.1 0.0018
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302) 159 41.1 0.002
>>NP_003197 (OMIM: 603306) transcription factor 21 [Homo (179 aa)
initn: 1165 init1: 1165 opt: 1165 Z-score: 1280.3 bits: 243.4 E(85289): 1.4e-64
Smith-Waterman score: 1165; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KB8 MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDT
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 LRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
130 140 150 160 170
>>NP_938206 (OMIM: 603306) transcription factor 21 [Homo (179 aa)
initn: 1165 init1: 1165 opt: 1165 Z-score: 1280.3 bits: 243.4 E(85289): 1.4e-64
Smith-Waterman score: 1165; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KB8 MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 KAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDT
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 LRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
130 140 150 160 170
>>NP_005089 (OMIM: 603628) musculin [Homo sapiens] (206 aa)
initn: 654 init1: 614 opt: 635 Z-score: 702.9 bits: 136.8 E(85289): 2.1e-32
Smith-Waterman score: 635; 71.5% identity (83.2% similar) in 137 aa overlap (44-178:70-206)
20 30 40 50 60 70
pF1KB8 EVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQ-KGRGGLGKRRKAPTKKS-PLSG
:. :. : :: : . :: : .:
NP_005 SPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKG
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB8 VSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHL
. : :: :::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_005 SAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHL
100 110 120 130 140 150
140 150 160 170
pF1KB8 RQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
::.: .:.:::::.:::::::::.:.:.:.:: ::: .:.:::::::
NP_005 RQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
160 170 180 190 200
>>NP_004600 (OMIM: 601010) transcription factor 15 [Homo (199 aa)
initn: 208 init1: 208 opt: 237 Z-score: 270.1 bits: 56.7 E(85289): 2.6e-08
Smith-Waterman score: 237; 38.2% identity (64.2% similar) in 123 aa overlap (25-143:21-137)
10 20 30 40 50
pF1KB8 MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRG---GLG
.. ..: . ......: .: .: :: : :
NP_004 MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGPEAARRGPGPGGG
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 KRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSK
.: . .:. : : :.::::::: : . .. ::. :.: .: : : ::::
NP_004 RRAGGGGGAGPVVVVRQ------RQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 LDTLRLASSYIAHLRQILA-NDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGT
..:::::::::::: ..: .:. ..:
NP_004 IETLRLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGAVPAAADGGRQPRSICTFCLS
120 130 140 150 160 170
>>XP_006716679 (OMIM: 609067) PREDICTED: basic helix-loo (201 aa)
initn: 199 init1: 199 opt: 222 Z-score: 253.7 bits: 53.7 E(85289): 2.1e-07
Smith-Waterman score: 223; 42.5% identity (67.9% similar) in 106 aa overlap (39-135:26-131)
10 20 30 40 50 60
pF1KB8 VEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQK------GRGGL-GKRRK
:. .. .:: .: .: :: : ::.
XP_006 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRR
10 20 30 40 50
70 80 90 100 110
pF1KB8 APTKKSPLSGVS-QEGKQV-QRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLD
: ... .: . . :.. ::..:::::: : .. ::. :.: .: : : ::::..
XP_006 AGGRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 TLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
:::::::::.:: ..:
XP_006 TLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQP
120 130 140 150 160 170
>>NP_001073983 (OMIM: 609067) basic helix-loop-helix tra (201 aa)
initn: 199 init1: 199 opt: 222 Z-score: 253.7 bits: 53.7 E(85289): 2.1e-07
Smith-Waterman score: 223; 42.5% identity (67.9% similar) in 106 aa overlap (39-135:26-131)
10 20 30 40 50 60
pF1KB8 VEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQK------GRGGL-GKRRK
:. .. .:: .: .: :: : ::.
NP_001 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRR
10 20 30 40 50
70 80 90 100 110
pF1KB8 APTKKSPLSGVS-QEGKQV-QRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLD
: ... .: . . :.. ::..:::::: : .. ::. :.: .: : : ::::..
NP_001 AGGRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 TLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
:::::::::.:: ..:
NP_001 TLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQP
120 130 140 150 160 170
>>XP_005264216 (OMIM: 609635) PREDICTED: transcription f (210 aa)
initn: 220 init1: 205 opt: 221 Z-score: 252.4 bits: 53.5 E(85289): 2.6e-07
Smith-Waterman score: 236; 38.4% identity (62.3% similar) in 138 aa overlap (49-171:44-179)
20 30 40 50 60 70
pF1KB8 ECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKR--RKAPTKKSPLSGVSQEG
: . :. ..: : .: .. .: :
XP_005 GVGHSQTQAKARLLPGADRKRSRLSRTRQDPWEERSWSNQRWSRATPGPRGTRAGGLALG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB8 KQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILA
.. ::::.:.:.: .:: :...:: :::::::::::.: ::.:::::: . :.
XP_005 RSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLG
80 90 100 110 120 130
140 150 160 170
pF1KB8 ND-------KYENG--YIHPVNLTWP----FMVAGKPESDLKEVVTASRLCGTTAS
.. . : :.::.. :: ....: ::: . .:::
XP_005 HELPGPAWPPFLRGLRYLHPLK-KWPMRSRLYAGGLGYSDL-DSTTASTPSQRTRDAETV
140 150 160 170 180 190
XP_005 THAYGPGFSTSPQILSHQT
200 210
>>NP_786951 (OMIM: 609635) transcription factor 23 [Homo (214 aa)
initn: 220 init1: 205 opt: 221 Z-score: 252.3 bits: 53.5 E(85289): 2.6e-07
Smith-Waterman score: 236; 38.4% identity (62.3% similar) in 138 aa overlap (49-171:44-179)
20 30 40 50 60 70
pF1KB8 ECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKR--RKAPTKKSPLSGVSQEG
: . :. ..: : .: .. .: :
NP_786 GVGHSQTQAKARLLPGADRKRSRLSRTRQDPWEERSWSNQRWSRATPGPRGTRAGGLALG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB8 KQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILA
.. ::::.:.:.: .:: :...:: :::::::::::.: ::.:::::: . :.
NP_786 RSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLG
80 90 100 110 120 130
140 150 160 170
pF1KB8 ND-------KYENG--YIHPVNLTWP----FMVAGKPESDLKEVVTASRLCGTTAS
.. . : :.::.. :: ....: ::: . .:::
NP_786 HELPGPAWPPFLRGLRYLHPLK-KWPMRSRLYAGGLGYSDL-DSTTASTPSQRTRDAEVG
140 150 160 170 180 190
NP_786 SQVPGEADALLSTTPLSPALGDK
200 210
>>NP_001258822 (OMIM: 200110,209885,227260,607556) twist (160 aa)
initn: 263 init1: 112 opt: 210 Z-score: 242.1 bits: 51.2 E(85289): 9.5e-07
Smith-Waterman score: 224; 35.4% identity (57.8% similar) in 161 aa overlap (1-156:1-147)
10 20 30 40 50 60
pF1KB8 MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRR
: :: : : .. . : . .. :.: . . ...:: :.::: :. :
NP_001 MEEGSSSPVSPVDSLGTSEEELERQP--KRFGRKRRYSKKSS--EDGSPTPGKRG-----
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDT
: :: :. : : : :: ::.::: : . :..::. :. .: .: : ::::..:
NP_001 ---KKGSP-SAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQT
60 70 80 90 100
130 140 150 160 170
pF1KB8 LRLASSYIAHLRQILANDKYEN-----GYIHPVNLTWPFMVAGKPESDLKEVVTASRLCG
:.::. :: : :.: .:...: .:. :.. : :
NP_001 LKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH
110 120 130 140 150 160
pF1KB8 TTAS
>>NP_476527 (OMIM: 200110,209885,227260,607556) twist-re (160 aa)
initn: 263 init1: 112 opt: 210 Z-score: 242.1 bits: 51.2 E(85289): 9.5e-07
Smith-Waterman score: 224; 35.4% identity (57.8% similar) in 161 aa overlap (1-156:1-147)
10 20 30 40 50 60
pF1KB8 MSTGSLSDVEDLQEVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGKRR
: :: : : .. . : . .. :.: . . ...:: :.::: :. :
NP_476 MEEGSSSPVSPVDSLGTSEEELERQP--KRFGRKRRYSKKSS--EDGSPTPGKRG-----
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 KAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDT
: :: :. : : : :: ::.::: : . :..::. :. .: .: : ::::..:
NP_476 ---KKGSP-SAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQT
60 70 80 90 100
130 140 150 160 170
pF1KB8 LRLASSYIAHLRQILANDKYEN-----GYIHPVNLTWPFMVAGKPESDLKEVVTASRLCG
:.::. :: : :.: .:...: .:. :.. : :
NP_476 LKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH
110 120 130 140 150 160
pF1KB8 TTAS
179 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:19:13 2016 done: Fri Nov 4 16:19:13 2016
Total Scan time: 5.320 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]