FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8846, 535 aa
  1>>>pF1KB8846 535 - 535 aa - 535 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9255+/-0.000892; mu= 11.0671+/- 0.053
 mean_var=110.8018+/-23.259, 0's: 0 Z-trim(108.8): 70  B-trim: 476 in 1/50
 Lambda= 0.121843
 statistics sampled from 10403 (10471) to 10403 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.322), width:  16
 Scan time:  3.590

The best scores are:                                      opt bits E(32554)
CCDS11998.1 SOCS6 gene_id:9306|Hs108|chr18         ( 535) 3590 642.1 4.9e-184
CCDS32637.1 SOCS7 gene_id:30837|Hs108|chr17        ( 581)  573 111.7 2.3e-24
CCDS9047.1 SOCS2 gene_id:8835|Hs108|chr12          ( 198)  339 70.4 2.3e-12


>>CCDS11998.1 SOCS6 gene_id:9306|Hs108|chr18              (535 aa)
 initn: 3590 init1: 3590 opt: 3590  Z-score: 3417.5  bits: 642.1 E(32554): 4.9e-184
Smith-Waterman score: 3590; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535)

               10        20        30        40        50        60
pF1KB8 MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 EKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDVRAQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDVRAQR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PIRSTSLRSHHYSPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PIRSTSLRSHHYSPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ETTCQEQANSLKSSASHNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ETTCQEQANSLKSSASHNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 CLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 RAGHDDVPPLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RAGHDDVPPLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 VQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGS
              430       440       450       460       470       480

              490       500       510       520       530     
pF1KB8 ATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY
              490       500       510       520       530     

>>CCDS32637.1 SOCS7 gene_id:30837|Hs108|chr17             (581 aa)
 initn: 527 init1: 317 opt: 573  Z-score: 550.8  bits: 111.7 E(32554): 2.3e-24
Smith-Waterman score: 612; 39.3% identity (61.6% similar) in 318 aa overlap (245-535:238-553)

          220       230       240       250        260       270   
pF1KB8 LMPQDYIQYTVPLDEGMYPLEGSRSYCLDSSSPMEVSAVP-PQVGGRAFPEDESQVDQDL
                                     :. . .::.   ..:: :  : ..     :
CCDS32 GSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKL
       210       220       230       240       250       260       

           280       290          300       310       320       330
pF1KB8 VVAPEIFVDQSVNGLLIGTTGVMLQ---SPRAGHDDVPPLSPLLPPMQNNQIQRNFSGLT
       . .   :   : . :. : :  ...   : :.  .  :: .:  :: .. ..  ..::  
CCDS32 TRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPP-TPPPPPRRSLSLLDDISGTL
       270       280       290       300        310       320      

              340                350         360                370
pF1KB8 GTEAHVAESMRCHLNFD---------PNSAPGVA--RVYDSVQSSGPMVV---------T
        : . ::       .:          :.. : .:  :. .:..:. :. .         .
CCDS32 PTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSS
        330       340       350       360       370       380      

              380       390        400       410       420         
pF1KB8 SLTEELKKLAKQGWYWGPITRWE-AEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTL
       :..  :..: : ::::::.. :: :: :: . :::::::::::: ::.:::::::.: : 
CCDS32 SFAASLRELEKCGWYWGPMN-WEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITH
        390       400        410       420       430       440     

     430       440       450        460       470        480       
pF1KB8 HTRIEHSNGRFSFYEQPDVEGHT-SIVDLIEHSIRDSENGAFCYS-RSRLPGSATYPVRL
       :::.::  : ::.. .:  : .  :.:..:...:  :.:: : :  :::.::    ::.:
CCDS32 HTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQL
         450       460       470       480       490       500     

       490       500       510       520       530                 
pF1KB8 TNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY            
         ::::: .:.:::.:::: ::: .::: :  ::::. . .:... .:            
CCDS32 LYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLK
         510       520       530       540       550       560     

CCDS32 EAQLISKQKQEVEPST
         570       580 

>>CCDS9047.1 SOCS2 gene_id:8835|Hs108|chr12               (198 aa)
 initn: 298 init1: 200 opt: 339  Z-score: 335.6  bits: 70.4 E(32554): 2.3e-12
Smith-Waterman score: 339; 31.9% identity (65.7% similar) in 207 aa overlap (339-535:2-196)

      310       320       330       340       350       360        
pF1KB8 PLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDSVQSS---G
                                     ..:: :. . :.. :.   . .. :.   .
CCDS90                              MTLRC-LEPSGNGGEGTRSQWGTAGSAEEPS
                                             10        20        30

         370       380       390       400       410       420     
pF1KB8 PMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSH
       :...  :.. :..:.. ::::: .:  ::. :: ..:.:.::.:::: . :::..: .. 
CCDS90 PQAAR-LAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTS
                40        50        60        70        80         

         430       440           450       460          470        
pF1KB8 GKTLHTRIEHSNGRFSFYE----QPDVEGHTSIVDLIEHSI---RDSENGAFCYSRSRLP
       .   . :::...:.: .      .  ..   :.: ::.. .   .:...:       . :
CCDS90 AGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGP------EAP
      90       100       110       120       130       140         

      480       490       500       510       520       530       
pF1KB8 GSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY  
        ..:  . ::.:.  . .. :::.:::..: . :    :  ::::...::::.: ..  
CCDS90 RNGTVHLYLTKPL--YTSAPSLQHLCRLTINKCT--GAIWGLPLPTRLKDYLEEYKFQV
           150         160       170         180       190        




535 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:04:43 2016 done: Fri Nov  4 16:04:44 2016
 Total Scan time:  3.590 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]