Result of FASTA (omim) for
pF1KB8835
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8835, 459 aa
1>>>pF1KB8835 459 - 459 aa - 459 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1479+/-0.000382; mu= -0.6429+/- 0.024
mean_var=448.1247+/-99.194, 0's: 0 Z-trim(124.7): 1290 B-trim: 2441 in 1/57
Lambda= 0.060586
statistics sampled from 45263 (46988) to 45263 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.551), width: 16
Scan time: 11.840
The best scores are: opt bits E(85289)
NP_006617 (OMIM: 605976) zinc finger and BTB domai ( 424) 555 62.5 2.6e-09
XP_011539548 (OMIM: 600871,607847,613107) PREDICTE ( 422) 338 43.5 0.0013
NP_005254 (OMIM: 600871,607847,613107) zinc finger ( 422) 338 43.5 0.0013
NP_001120687 (OMIM: 600871,607847,613107) zinc fin ( 422) 338 43.5 0.0013
XP_011539547 (OMIM: 600871,607847,613107) PREDICTE ( 422) 338 43.5 0.0013
XP_005270806 (OMIM: 600871,607847,613107) PREDICTE ( 422) 338 43.5 0.0013
NP_001120688 (OMIM: 600871,607847,613107) zinc fin ( 422) 338 43.5 0.0013
NP_006488 (OMIM: 603825) hypermethylated in cancer ( 714) 343 44.2 0.0014
NP_001091672 (OMIM: 603825) hypermethylated in can ( 733) 343 44.2 0.0014
NP_001092740 (OMIM: 611692) zinc finger and BTB do ( 500) 323 42.3 0.0037
XP_011517001 (OMIM: 611692) PREDICTED: zinc finger ( 504) 323 42.3 0.0037
XP_005252046 (OMIM: 611692) PREDICTED: zinc finger ( 514) 323 42.3 0.0037
XP_011512891 (OMIM: 611643) PREDICTED: zinc finger ( 390) 318 41.7 0.0043
NP_001291435 (OMIM: 611643) zinc finger protein wi ( 390) 318 41.7 0.0043
XP_016866333 (OMIM: 611643) PREDICTED: zinc finger ( 390) 318 41.7 0.0043
XP_006715158 (OMIM: 611643) PREDICTED: zinc finger ( 408) 318 41.7 0.0044
XP_005249157 (OMIM: 611643) PREDICTED: zinc finger ( 418) 318 41.7 0.0045
XP_005249155 (OMIM: 611643) PREDICTED: zinc finger ( 442) 318 41.8 0.0046
XP_005249154 (OMIM: 611643) PREDICTED: zinc finger ( 442) 318 41.8 0.0046
XP_011512890 (OMIM: 611643) PREDICTED: zinc finger ( 516) 318 41.9 0.0051
NP_061983 (OMIM: 611643) zinc finger protein with ( 545) 318 41.9 0.0052
XP_005249152 (OMIM: 611643) PREDICTED: zinc finger ( 545) 318 41.9 0.0052
XP_005259428 (OMIM: 610671) PREDICTED: zinc finger (1055) 322 42.6 0.0062
NP_149104 (OMIM: 610671) zinc finger protein 628 [ (1059) 322 42.6 0.0062
NP_008894 (OMIM: 194529) zinc finger protein 22 [H ( 224) 305 40.3 0.0067
NP_001292132 (OMIM: 609451) zinc finger protein 90 ( 636) 315 41.7 0.0069
NP_597715 (OMIM: 609451) zinc finger protein 90 ho ( 636) 315 41.7 0.0069
XP_005255861 (OMIM: 609451) PREDICTED: zinc finger ( 636) 315 41.7 0.0069
XP_016878441 (OMIM: 609451) PREDICTED: zinc finger ( 720) 315 41.8 0.0075
XP_005250017 (OMIM: 614040) PREDICTED: zinc finger ( 595) 312 41.4 0.008
XP_011514160 (OMIM: 614040) PREDICTED: zinc finger ( 595) 312 41.4 0.008
XP_005250016 (OMIM: 614040) PREDICTED: zinc finger ( 595) 312 41.4 0.008
NP_997219 (OMIM: 614040) zinc finger protein 467 i ( 595) 312 41.4 0.008
XP_005250018 (OMIM: 614040) PREDICTED: zinc finger ( 595) 312 41.4 0.008
XP_005259409 (OMIM: 609133) PREDICTED: flt3-intera ( 496) 310 41.1 0.008
NP_116225 (OMIM: 609133) flt3-interacting zinc fin ( 496) 310 41.1 0.008
XP_011515874 (OMIM: 611781) PREDICTED: PR domain z ( 316) 305 40.4 0.0082
XP_006715927 (OMIM: 614040) PREDICTED: zinc finger ( 636) 312 41.4 0.0083
NP_008887 (OMIM: 194536) zinc finger protein 12 is ( 659) 312 41.5 0.0085
NP_057349 (OMIM: 194536) zinc finger protein 12 is ( 697) 312 41.5 0.0088
XP_016862357 (OMIM: 606042) PREDICTED: myoneurin i ( 309) 303 40.3 0.0092
NP_001229824 (OMIM: 612791) zinc finger protein wi ( 390) 305 40.6 0.0094
XP_006715281 (OMIM: 612791) PREDICTED: zinc finger ( 390) 305 40.6 0.0094
XP_011517372 (OMIM: 187900,604383) PREDICTED: zinc ( 330) 303 40.3 0.0096
NP_004179 (OMIM: 187900,604383) zinc finger protei ( 330) 303 40.3 0.0096
XP_005249480 (OMIM: 612791) PREDICTED: zinc finger ( 405) 305 40.6 0.0096
XP_016862356 (OMIM: 606042) PREDICTED: myoneurin i ( 337) 303 40.3 0.0097
>>NP_006617 (OMIM: 605976) zinc finger and BTB domain-co (424 aa)
initn: 1034 init1: 460 opt: 555 Z-score: 288.1 bits: 62.5 E(85289): 2.6e-09
Smith-Waterman score: 825; 33.9% identity (62.3% similar) in 448 aa overlap (1-446:1-413)
10 20 30 40 50 60
pF1KB8 MASGVEVLRFQLPGHEAATLRNMNQLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRD
::. .::.::. . ..:..:: :: .. ::::.: .. .:.:::::::::: :.::
NP_006 MAAESDVLHFQFEQQGDVVLQKMNLLRQQNLFCDVSIYINDTEFQGHKVILAACSTFMRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 QFLLNPSSELQVSLMHSARIVADLLLSCYTGALEFAVRDIVNYLTAASYLQMEHVVEKCR
::::. :.........::.. ::::::::::: .....:::::::::: :.::::
NP_006 QFLLTQSKHVRITILQSAEVGRKLLLSCYTGALEVKRKELLKYLTAASYLQMVHIVEKCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NALSQFIEPKIGLKEDGVSEASLVSSISATKSLLPPARTPKPAPKPPPPPPLPPPLLRPV
.:::...: ...:... ....: .: : : . .
NP_006 EALSKYLEIDLSMKNNN-QHTDLCQS-------------SDPDVKNEDENSDKDCEIIEI
130 140 150 160
190 200 210 220 230
pF1KB8 KLEFPLDEDLELKAEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGLGGGLGIGGS--
. . :.. :...: :: :. ::: ...: : .:. .
NP_006 SEDSPVNIDFHVKEEE---------SNALQSTVESLTSERKEMKSPELSTVDIGFKDNEI
170 180 190 200 210
240 250 260 270 280 290
pF1KB8 VGGHLGELAQSSVPPSTVAPPQGVVKACYSLSEDAEGEGLLLIPGGRASVGATSGLVEAA
:. .. ..: . . : :: . .:: .. :. .. :. . : . .
NP_006 CILHVESISTAGVENGQFSQPCTSSKASMYFSETQHS---LINSTVESRVAEVPGNQDQG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB8 AVAMAARGAGGSLGAGGSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHFI
..:. :... . : :.: :.. .: .::. : ::. . :.. .: .
NP_006 LFCENTEGSYGTVSEIQN---LEEGYS----LRH-QCPRCPRGFLHVENYLRHLK-MHKL
280 290 300 310 320
360 370 380 390 400 410
pF1KB8 FMCPRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCS
:.: .::: :....:::::. : :.. .: .: : :: ::::.::::.::: :::.:
NP_006 FLCLQCGKTFTQKKNLNRHIRGHMGIRPFQCTVCLKTFTAKSTLQDHLNIHSGDRPYKCH
330 340 350 360 370 380
420 430 440 450
pF1KB8 YCDVRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
::. : :: :...:: ::....:..
NP_006 CCDMDFKHKSALKKHLTSVHGRSSGEKLSRPDLKRQSLL
390 400 410 420
>>XP_011539548 (OMIM: 600871,607847,613107) PREDICTED: z (422 aa)
initn: 477 init1: 308 opt: 338 Z-score: 185.6 bits: 43.5 E(85289): 0.0013
Smith-Waterman score: 346; 33.8% identity (55.4% similar) in 222 aa overlap (224-433:140-358)
200 210 220 230 240 250
pF1KB8 AEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGL--GGGLGIGGSVGGHLGELAQSSV
.: :.: :.:::. . . :. :
XP_011 DEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYG
110 120 130 140 150 160
260 270 280 290 300
pF1KB8 PPSTVAPP-QGVVKACYSLSEDAEGEGLLLIPG-GRASVGATSGLVEAAAVAMAARGAG-
: ... :. .: . . . : :: : : :..: . ::.. . :: :
XP_011 PKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGL
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB8 -GSLGAG---GSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHF---IFMC
.. ::: :. . ::. . :: :: .::. . : :.: .: : :
XP_011 HADKGAGVKVESELLCTRLLLGGG---SYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFAC
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB8 PRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCD
::: :.:. .:..: :: .: .: :::: : ..::: :: .:: .::: :.::
XP_011 EMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCG
290 300 310 320 330 340
430 440 450
pF1KB8 VRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
:: .: ...:
XP_011 KRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQ
350 360 370 380 390 400
>>NP_005254 (OMIM: 600871,607847,613107) zinc finger pro (422 aa)
initn: 477 init1: 308 opt: 338 Z-score: 185.6 bits: 43.5 E(85289): 0.0013
Smith-Waterman score: 346; 33.8% identity (55.4% similar) in 222 aa overlap (224-433:140-358)
200 210 220 230 240 250
pF1KB8 AEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGL--GGGLGIGGSVGGHLGELAQSSV
.: :.: :.:::. . . :. :
NP_005 DEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYG
110 120 130 140 150 160
260 270 280 290 300
pF1KB8 PPSTVAPP-QGVVKACYSLSEDAEGEGLLLIPG-GRASVGATSGLVEAAAVAMAARGAG-
: ... :. .: . . . : :: : : :..: . ::.. . :: :
NP_005 PKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGL
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB8 -GSLGAG---GSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHF---IFMC
.. ::: :. . ::. . :: :: .::. . : :.: .: : :
NP_005 HADKGAGVKVESELLCTRLLLGGG---SYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFAC
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB8 PRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCD
::: :.:. .:..: :: .: .: :::: : ..::: :: .:: .::: :.::
NP_005 EMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCG
290 300 310 320 330 340
430 440 450
pF1KB8 VRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
:: .: ...:
NP_005 KRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQ
350 360 370 380 390 400
>>NP_001120687 (OMIM: 600871,607847,613107) zinc finger (422 aa)
initn: 477 init1: 308 opt: 338 Z-score: 185.6 bits: 43.5 E(85289): 0.0013
Smith-Waterman score: 346; 33.8% identity (55.4% similar) in 222 aa overlap (224-433:140-358)
200 210 220 230 240 250
pF1KB8 AEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGL--GGGLGIGGSVGGHLGELAQSSV
.: :.: :.:::. . . :. :
NP_001 DEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYG
110 120 130 140 150 160
260 270 280 290 300
pF1KB8 PPSTVAPP-QGVVKACYSLSEDAEGEGLLLIPG-GRASVGATSGLVEAAAVAMAARGAG-
: ... :. .: . . . : :: : : :..: . ::.. . :: :
NP_001 PKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGL
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB8 -GSLGAG---GSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHF---IFMC
.. ::: :. . ::. . :: :: .::. . : :.: .: : :
NP_001 HADKGAGVKVESELLCTRLLLGGG---SYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFAC
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB8 PRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCD
::: :.:. .:..: :: .: .: :::: : ..::: :: .:: .::: :.::
NP_001 EMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCG
290 300 310 320 330 340
430 440 450
pF1KB8 VRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
:: .: ...:
NP_001 KRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQ
350 360 370 380 390 400
>>XP_011539547 (OMIM: 600871,607847,613107) PREDICTED: z (422 aa)
initn: 477 init1: 308 opt: 338 Z-score: 185.6 bits: 43.5 E(85289): 0.0013
Smith-Waterman score: 346; 33.8% identity (55.4% similar) in 222 aa overlap (224-433:140-358)
200 210 220 230 240 250
pF1KB8 AEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGL--GGGLGIGGSVGGHLGELAQSSV
.: :.: :.:::. . . :. :
XP_011 DEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYG
110 120 130 140 150 160
260 270 280 290 300
pF1KB8 PPSTVAPP-QGVVKACYSLSEDAEGEGLLLIPG-GRASVGATSGLVEAAAVAMAARGAG-
: ... :. .: . . . : :: : : :..: . ::.. . :: :
XP_011 PKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGL
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB8 -GSLGAG---GSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHF---IFMC
.. ::: :. . ::. . :: :: .::. . : :.: .: : :
XP_011 HADKGAGVKVESELLCTRLLLGGG---SYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFAC
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB8 PRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCD
::: :.:. .:..: :: .: .: :::: : ..::: :: .:: .::: :.::
XP_011 EMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCG
290 300 310 320 330 340
430 440 450
pF1KB8 VRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
:: .: ...:
XP_011 KRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQ
350 360 370 380 390 400
>>XP_005270806 (OMIM: 600871,607847,613107) PREDICTED: z (422 aa)
initn: 477 init1: 308 opt: 338 Z-score: 185.6 bits: 43.5 E(85289): 0.0013
Smith-Waterman score: 346; 33.8% identity (55.4% similar) in 222 aa overlap (224-433:140-358)
200 210 220 230 240 250
pF1KB8 AEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGL--GGGLGIGGSVGGHLGELAQSSV
.: :.: :.:::. . . :. :
XP_005 DEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYG
110 120 130 140 150 160
260 270 280 290 300
pF1KB8 PPSTVAPP-QGVVKACYSLSEDAEGEGLLLIPG-GRASVGATSGLVEAAAVAMAARGAG-
: ... :. .: . . . : :: : : :..: . ::.. . :: :
XP_005 PKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGL
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB8 -GSLGAG---GSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHF---IFMC
.. ::: :. . ::. . :: :: .::. . : :.: .: : :
XP_005 HADKGAGVKVESELLCTRLLLGGG---SYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFAC
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB8 PRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCD
::: :.:. .:..: :: .: .: :::: : ..::: :: .:: .::: :.::
XP_005 EMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCG
290 300 310 320 330 340
430 440 450
pF1KB8 VRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
:: .: ...:
XP_005 KRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQ
350 360 370 380 390 400
>>NP_001120688 (OMIM: 600871,607847,613107) zinc finger (422 aa)
initn: 477 init1: 308 opt: 338 Z-score: 185.6 bits: 43.5 E(85289): 0.0013
Smith-Waterman score: 346; 33.8% identity (55.4% similar) in 222 aa overlap (224-433:140-358)
200 210 220 230 240 250
pF1KB8 AEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGL--GGGLGIGGSVGGHLGELAQSSV
.: :.: :.:::. . . :. :
NP_001 DEAQPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGLFCEPAPEPGHPAALYG
110 120 130 140 150 160
260 270 280 290 300
pF1KB8 PPSTVAPP-QGVVKACYSLSEDAEGEGLLLIPG-GRASVGATSGLVEAAAVAMAARGAG-
: ... :. .: . . . : :: : : :..: . ::.. . :: :
NP_001 PKRAAGGAGAGAPGSCSAGAGATAGPGLGLYGDFGSAAAGLYERPTAAAGLLYPERGHGL
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB8 -GSLGAG---GSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHF---IFMC
.. ::: :. . ::. . :: :: .::. . : :.: .: : :
NP_001 HADKGAGVKVESELLCTRLLLGGG---SYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFAC
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB8 PRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCD
::: :.:. .:..: :: .: .: :::: : ..::: :: .:: .::: :.::
NP_001 EMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCG
290 300 310 320 330 340
430 440 450
pF1KB8 VRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
:: .: ...:
NP_001 KRFHQKSDMKKHTFIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQ
350 360 370 380 390 400
>>NP_006488 (OMIM: 603825) hypermethylated in cancer 1 p (714 aa)
initn: 594 init1: 231 opt: 343 Z-score: 185.5 bits: 44.2 E(85289): 0.0014
Smith-Waterman score: 402; 31.2% identity (53.6% similar) in 304 aa overlap (162-435:295-592)
140 150 160 170 180 190
pF1KB8 GLKEDGVSEASLVSSISATKSLLPPARTPKPAPKPPPPPPLPPPLLRPVKLEFPLDE-DL
:.:.:: : : : : .: : :
NP_006 LALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGD
270 280 290 300 310 320
200 210 220 230 240
pF1KB8 ELKAEEEDEDE--DEDVSDICIVKVESALEVAHRLKPPGGLGG-GLGIGGSVGGHLGELA
:: :. . .: .: .: . : .: . ::.: : : : :. .: .
NP_006 ELGRERGSPSERCEERGGDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEET
330 340 350 360 370 380
250 260 270 280 290
pF1KB8 QSSVPPSTVAPPQGVVKA--CYSLS---EDAEGEGLLL-IPGGR---------ASVGA--
:: :: :: : ... : :. .. :..: . :: :. : : :
NP_006 GSSEDPS---PPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHV
390 400 410 420 430 440
300 310 320 330 340
pF1KB8 -----TSGLVEAAAVAMAARGAGGSLGAGGSR-GPLPGGFSGGNPLKNIKCTKCPEVFQG
: .::: :: .: : : .:.::.. . :::. :. :. .:..: . ..
NP_006 EEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGL--GELLRPYRCASCDKSYKD
450 460 470 480 490
350 360 370 380 390 400
pF1KB8 VEKLVFHMRAQHFI---FMCPRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKST
: : .. :.. . : :::.:.. ....::: : :.: .: :: ::..
NP_006 PATLRQHEKT-HWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYR
500 510 520 530 540 550
410 420 430 440 450
pF1KB8 LHDHLNLHSGARPYRCSYCDVRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
: .:. .::: .::.:. : .::.. . :.:
NP_006 LTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGP
560 570 580 590 600 610
NP_006 DGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPKVALESLYPLAKF
620 630 640 650 660 670
>>NP_001091672 (OMIM: 603825) hypermethylated in cancer (733 aa)
initn: 594 init1: 231 opt: 343 Z-score: 185.4 bits: 44.2 E(85289): 0.0014
Smith-Waterman score: 402; 31.2% identity (53.6% similar) in 304 aa overlap (162-435:314-611)
140 150 160 170 180 190
pF1KB8 GLKEDGVSEASLVSSISATKSLLPPARTPKPAPKPPPPPPLPPPLLRPVKLEFPLDE-DL
:.:.:: : : : : .: : :
NP_001 LALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGD
290 300 310 320 330 340
200 210 220 230 240
pF1KB8 ELKAEEEDEDE--DEDVSDICIVKVESALEVAHRLKPPGGLGG-GLGIGGSVGGHLGELA
:: :. . .: .: .: . : .: . ::.: : : : :. .: .
NP_001 ELGRERGSPSERCEERGGDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEET
350 360 370 380 390 400
250 260 270 280 290
pF1KB8 QSSVPPSTVAPPQGVVKA--CYSLS---EDAEGEGLLL-IPGGR---------ASVGA--
:: :: :: : ... : :. .. :..: . :: :. : : :
NP_001 GSSEDPS---PPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHV
410 420 430 440 450 460
300 310 320 330 340
pF1KB8 -----TSGLVEAAAVAMAARGAGGSLGAGGSR-GPLPGGFSGGNPLKNIKCTKCPEVFQG
: .::: :: .: : : .:.::.. . :::. :. :. .:..: . ..
NP_001 EEEEALYGRAEAAEVAAGAAGLGPPFGGGGDKVAGAPGGL--GELLRPYRCASCDKSYKD
470 480 490 500 510
350 360 370 380 390 400
pF1KB8 VEKLVFHMRAQHFI---FMCPRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKST
: : .. :.. . : :::.:.. ....::: : :.: .: :: ::..
NP_001 PATLRQHEKT-HWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYR
520 530 540 550 560 570
410 420 430 440 450
pF1KB8 LHDHLNLHSGARPYRCSYCDVRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
: .:. .::: .::.:. : .::.. . :.:
NP_001 LTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGP
580 590 600 610 620 630
NP_001 DGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDPKVALESLYPLAKF
640 650 660 670 680 690
>>NP_001092740 (OMIM: 611692) zinc finger and BTB domain (500 aa)
initn: 715 init1: 317 opt: 323 Z-score: 177.7 bits: 42.3 E(85289): 0.0037
Smith-Waterman score: 512; 26.8% identity (54.6% similar) in 471 aa overlap (8-438:7-451)
10 20 30 40 50 60
pF1KB8 MASGVEVLRFQLPGHEAATLRNMNQLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRD
..:..: . ...: ..:.:: . ..::. . .. ::.::..::: ::..::
NP_001 MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRD
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 QFLLNPSSELQVSLMHSARIVADLLLSCYTGALEFAVRDIVNYLTAASYLQMEHVVEKCR
. :. : :..:.... . .:: :::: . . ..:.:..:::::.:::. :..::
NP_001 HSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCT
60 70 80 90 100 110
130 140 150 160
pF1KB8 NALSQFIEPKI----------GLKED-----GVSEASLVSS-ISATKSLLPPARTPKPAP
. : . :. :: : .:. ::...:. .. . . .: : :
NP_001 QILES-IHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPT-AS
120 130 140 150 160 170
170 180 190 200 210
pF1KB8 KPPPPPPLPPPLLRP-VKLEFPLDE-------DLELKAEEEDEDEDEDVSDICIVKVESA
. : :: .. : :. . :.. : . :. : : . :..:.
NP_001 SDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVK
180 190 200 210 220 230
220 230 240 250 260
pF1KB8 LEVAHRLKPPGGLGGGLGIGG--------------SVGGHLGELAQSSVPPSTVAP-PQG
.: . : : . ...:: : .::.. : . : . : .: : .
NP_001 MEKSDR--PSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSY-GSVLQHAYSYSQAASQPTN
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB8 VVKACYSLSEDAEGEGLL-LIPGGRASVGATSGLVEAAAVAMAARGAGGSLGAGGSRGPL
: .: :::... ....: . :::: .: .: . . : :. .
NP_001 VSEAFGSLSNSSPSRSMLSCFRGGRARQK------RALSVHLHSDLQGLVQGSDSEAMMN
300 310 320 330 340
330 340 350 360 370 380
pF1KB8 PGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHFIFMCPRCGKQFNHSSNLNRHMNV
:. .. .. . : :.:. : :::.::....:.::: .
NP_001 NPGYESSPRERSARGHWYPYN----ERLI-----------CIYCGKSFNQKGSLDRHMRL
350 360 370 380 390
390 400 410 420 430 440
pF1KB8 HRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCDVRFAHKPAIRRHLKEQHGK
: :. : .::: .:.:. :. :. :. .:.:: : : . .. .::...:
NP_001 HMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPG
400 410 420 430 440 450
450
pF1KB8 TTAENVLEASVAEINVLIR
NP_001 VAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
460 470 480 490 500
459 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:58:18 2016 done: Fri Nov 4 15:58:20 2016
Total Scan time: 11.840 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]