Result of FASTA (omim) for
pF1KB8830
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8830, 440 aa
1>>>pF1KB8830 440 - 440 aa - 440 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3047+/-0.000421; mu= 12.4708+/- 0.026
mean_var=88.3772+/-18.234, 0's: 0 Z-trim(112.9): 85 B-trim: 648 in 1/48
Lambda= 0.136428
statistics sampled from 21908 (21995) to 21908 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.258), width: 16
Scan time: 8.230
The best scores are: opt bits E(85289)
XP_011534727 (OMIM: 616337) PREDICTED: suppressor ( 440) 3048 610.3 3.2e-174
XP_011534728 (OMIM: 616337) PREDICTED: suppressor ( 440) 3048 610.3 3.2e-174
NP_955453 (OMIM: 616337) suppressor of cytokine si ( 440) 3048 610.3 3.2e-174
NP_543143 (OMIM: 616337) suppressor of cytokine si ( 440) 3048 610.3 3.2e-174
NP_659198 (OMIM: 607094) suppressor of cytokine si ( 536) 1160 238.7 2.8e-62
NP_054730 (OMIM: 607094) suppressor of cytokine si ( 536) 1160 238.7 2.8e-62
XP_005266840 (OMIM: 605118) PREDICTED: suppressor ( 535) 232 56.0 2.7e-07
NP_004223 (OMIM: 605118) suppressor of cytokine si ( 535) 232 56.0 2.7e-07
XP_016881576 (OMIM: 605118) PREDICTED: suppressor ( 535) 232 56.0 2.7e-07
XP_016881575 (OMIM: 605118) PREDICTED: suppressor ( 535) 232 56.0 2.7e-07
NP_659508 (OMIM: 602441,607948,611162,614383) cyto ( 258) 207 51.0 4.4e-06
XP_011531631 (OMIM: 602441,607948,611162,614383) P ( 264) 207 51.0 4.5e-06
NP_037456 (OMIM: 602441,607948,611162,614383) cyto ( 275) 207 51.0 4.6e-06
XP_016880041 (OMIM: 608788) PREDICTED: suppressor ( 576) 195 48.8 4.5e-05
NP_055413 (OMIM: 608788) suppressor of cytokine si ( 581) 195 48.8 4.5e-05
XP_016880040 (OMIM: 608788) PREDICTED: suppressor ( 611) 195 48.8 4.7e-05
NP_003736 (OMIM: 603597) suppressor of cytokine si ( 211) 184 46.4 8.5e-05
NP_001257398 (OMIM: 605117) suppressor of cytokine ( 198) 159 41.5 0.0024
NP_001257397 (OMIM: 605117) suppressor of cytokine ( 198) 159 41.5 0.0024
NP_001257399 (OMIM: 605117) suppressor of cytokine ( 198) 159 41.5 0.0024
NP_001257396 (OMIM: 605117) suppressor of cytokine ( 198) 159 41.5 0.0024
NP_001257400 (OMIM: 605117) suppressor of cytokine ( 198) 159 41.5 0.0024
NP_003868 (OMIM: 605117) suppressor of cytokine si ( 198) 159 41.5 0.0024
XP_016875645 (OMIM: 605117) PREDICTED: suppressor ( 198) 159 41.5 0.0024
XP_011537238 (OMIM: 605117) PREDICTED: suppressor ( 204) 159 41.5 0.0025
XP_011537237 (OMIM: 605117) PREDICTED: suppressor ( 212) 159 41.5 0.0026
XP_011537231 (OMIM: 605117) PREDICTED: suppressor ( 220) 159 41.5 0.0027
XP_016875644 (OMIM: 605117) PREDICTED: suppressor ( 222) 159 41.5 0.0027
XP_016875640 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
XP_016875642 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
XP_016875643 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
XP_016875641 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
XP_016875636 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
XP_016875637 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
XP_016875639 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
XP_016875638 (OMIM: 605117) PREDICTED: suppressor ( 243) 159 41.5 0.0029
>>XP_011534727 (OMIM: 616337) PREDICTED: suppressor of c (440 aa)
initn: 3048 init1: 3048 opt: 3048 Z-score: 3248.7 bits: 610.3 E(85289): 3.2e-174
Smith-Waterman score: 3048; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB8 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
370 380 390 400 410 420
430 440
pF1KB8 EYHYKSKVRVLRIDAPEQQC
::::::::::::::::::::
XP_011 EYHYKSKVRVLRIDAPEQQC
430 440
>>XP_011534728 (OMIM: 616337) PREDICTED: suppressor of c (440 aa)
initn: 3048 init1: 3048 opt: 3048 Z-score: 3248.7 bits: 610.3 E(85289): 3.2e-174
Smith-Waterman score: 3048; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB8 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
370 380 390 400 410 420
430 440
pF1KB8 EYHYKSKVRVLRIDAPEQQC
::::::::::::::::::::
XP_011 EYHYKSKVRVLRIDAPEQQC
430 440
>>NP_955453 (OMIM: 616337) suppressor of cytokine signal (440 aa)
initn: 3048 init1: 3048 opt: 3048 Z-score: 3248.7 bits: 610.3 E(85289): 3.2e-174
Smith-Waterman score: 3048; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB8 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
370 380 390 400 410 420
430 440
pF1KB8 EYHYKSKVRVLRIDAPEQQC
::::::::::::::::::::
NP_955 EYHYKSKVRVLRIDAPEQQC
430 440
>>NP_543143 (OMIM: 616337) suppressor of cytokine signal (440 aa)
initn: 3048 init1: 3048 opt: 3048 Z-score: 3248.7 bits: 610.3 E(85289): 3.2e-174
Smith-Waterman score: 3048; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB8 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 SLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 KIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 MEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 LEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLK
370 380 390 400 410 420
430 440
pF1KB8 EYHYKSKVRVLRIDAPEQQC
::::::::::::::::::::
NP_543 EYHYKSKVRVLRIDAPEQQC
430 440
>>NP_659198 (OMIM: 607094) suppressor of cytokine signal (536 aa)
initn: 1399 init1: 1035 opt: 1160 Z-score: 1239.1 bits: 238.7 E(85289): 2.8e-62
Smith-Waterman score: 1496; 54.2% identity (77.3% similar) in 437 aa overlap (7-430:93-525)
10 20 30
pF1KB8 MAENNENISKNVD--VRPKTSRSRSADRKDGYVWSG
.: :. : : : : .: . . :.:
NP_659 IALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGG
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB8 KKL-SWSKKSESYSDAETVNGIEKTEVSLRNQERKHSCSSIELDLDHSCGHRFLG-RSLK
:: : : :..: ::. : .:. .:. .::... ::.. :.: : . : .: :::.
NP_659 KKKHSCSTKTQSSLDADKKFG--RTRSGLQRRERRYGVSSVH-DMD-SVSSRTVGSRSLR
130 140 150 160 170
100 110 120 130 140 150
pF1KB8 QKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTA
:.:::.:: :::... :.. . . .:::::.:::::.::::: :::: .::.::.:::
NP_659 QRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTA
180 190 200 210 220 230
160 170 180 190 200
pF1KB8 PINSKSDEWVSTD--LSQTELRDGQLKRR---NMEENINCFSHTNVQPCVITTD-NALCR
:.. .: . . : : .:: .. .:..: ..::... ..... :.. : : .
NP_659 PVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYK
240 250 260 270 280 290
210 220 230 240 250 260
pF1KB8 EGPMTGSVMNLVSNNS--IEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEI-LQLETPPK
:: . :. .:..: : ... ::... ::: .::.... . . :.. .. . :
NP_659 LGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWK
300 310 320 330 340 350
270 280 290 300 310 320
pF1KB8 YHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVS
::::::.::::::::::..:::::::::.: ::::::::::::::::::::::::::::
NP_659 VHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVS
360 370 380 390 400 410
330 340 350 360 370 380
pF1KB8 FRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIR
::::.:::::::::::::::::::::::::: .:::::::::::.::::::::. : :
NP_659 FRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNR
420 430 440 450 460 470
390 400 410 420 430 440
pF1KB8 TFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
:::::::.:::.::: ::::::::.::.:: .. .:::::::.::::
NP_659 TFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK
480 490 500 510 520 530
>>NP_054730 (OMIM: 607094) suppressor of cytokine signal (536 aa)
initn: 1399 init1: 1035 opt: 1160 Z-score: 1239.1 bits: 238.7 E(85289): 2.8e-62
Smith-Waterman score: 1496; 54.2% identity (77.3% similar) in 437 aa overlap (7-430:93-525)
10 20 30
pF1KB8 MAENNENISKNVD--VRPKTSRSRSADRKDGYVWSG
.: :. : : : : .: . . :.:
NP_054 IALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGG
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB8 KKL-SWSKKSESYSDAETVNGIEKTEVSLRNQERKHSCSSIELDLDHSCGHRFLG-RSLK
:: : : :..: ::. : .:. .:. .::... ::.. :.: : . : .: :::.
NP_054 KKKHSCSTKTQSSLDADKKFG--RTRSGLQRRERRYGVSSVH-DMD-SVSSRTVGSRSLR
130 140 150 160 170
100 110 120 130 140 150
pF1KB8 QKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTA
:.:::.:: :::... :.. . . .:::::.:::::.::::: :::: .::.::.:::
NP_054 QRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTA
180 190 200 210 220 230
160 170 180 190 200
pF1KB8 PINSKSDEWVSTD--LSQTELRDGQLKRR---NMEENINCFSHTNVQPCVITTD-NALCR
:.. .: . . : : .:: .. .:..: ..::... ..... :.. : : .
NP_054 PVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYK
240 250 260 270 280 290
210 220 230 240 250 260
pF1KB8 EGPMTGSVMNLVSNNS--IEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEI-LQLETPPK
:: . :. .:..: : ... ::... ::: .::.... . . :.. .. . :
NP_054 LGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWK
300 310 320 330 340 350
270 280 290 300 310 320
pF1KB8 YHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVS
::::::.::::::::::..:::::::::.: ::::::::::::::::::::::::::::
NP_054 VHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVS
360 370 380 390 400 410
330 340 350 360 370 380
pF1KB8 FRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIR
::::.:::::::::::::::::::::::::: .:::::::::::.::::::::. : :
NP_054 FRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNR
420 430 440 450 460 470
390 400 410 420 430 440
pF1KB8 TFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
:::::::.:::.::: ::::::::.::.:: .. .:::::::.::::
NP_054 TFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK
480 490 500 510 520 530
>>XP_005266840 (OMIM: 605118) PREDICTED: suppressor of c (535 aa)
initn: 341 init1: 200 opt: 232 Z-score: 252.0 bits: 56.0 E(85289): 2.7e-07
Smith-Waterman score: 319; 36.9% identity (60.7% similar) in 168 aa overlap (271-424:369-535)
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
: :. .: .. .. ::: . .. ::. :
XP_005 SMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKL
340 350 360 370 380 390
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
. :.:.::.:::... ::.:.::: ....::.:::. : ::: ..: : .:. :
XP_005 ANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSF-YEQPDVEGHTSIVDL
400 410 420 430 440 450
370 380 390 400
pF1KB8 LEH-YKDPSACMFFEPLLSTPLIRTFPF-------------SLQHICRTVICNCTTYDGI
.:: .: : : :.: :::..:: :: . : : :
XP_005 IEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLI
460 470 480 490 500 510
410 420 430 440
pF1KB8 DALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
. ::.:..:: ::.: ::
XP_005 QKLPLPNKMKDYLQEKHY
520 530
>>NP_004223 (OMIM: 605118) suppressor of cytokine signal (535 aa)
initn: 341 init1: 200 opt: 232 Z-score: 252.0 bits: 56.0 E(85289): 2.7e-07
Smith-Waterman score: 319; 36.9% identity (60.7% similar) in 168 aa overlap (271-424:369-535)
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
: :. .: .. .. ::: . .. ::. :
NP_004 SMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKL
340 350 360 370 380 390
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
. :.:.::.:::... ::.:.::: ....::.:::. : ::: ..: : .:. :
NP_004 ANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSF-YEQPDVEGHTSIVDL
400 410 420 430 440 450
370 380 390 400
pF1KB8 LEH-YKDPSACMFFEPLLSTPLIRTFPF-------------SLQHICRTVICNCTTYDGI
.:: .: : : :.: :::..:: :: . : : :
NP_004 IEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLI
460 470 480 490 500 510
410 420 430 440
pF1KB8 DALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
. ::.:..:: ::.: ::
NP_004 QKLPLPNKMKDYLQEKHY
520 530
>>XP_016881576 (OMIM: 605118) PREDICTED: suppressor of c (535 aa)
initn: 341 init1: 200 opt: 232 Z-score: 252.0 bits: 56.0 E(85289): 2.7e-07
Smith-Waterman score: 319; 36.9% identity (60.7% similar) in 168 aa overlap (271-424:369-535)
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
: :. .: .. .. ::: . .. ::. :
XP_016 SMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKL
340 350 360 370 380 390
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
. :.:.::.:::... ::.:.::: ....::.:::. : ::: ..: : .:. :
XP_016 ANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSF-YEQPDVEGHTSIVDL
400 410 420 430 440 450
370 380 390 400
pF1KB8 LEH-YKDPSACMFFEPLLSTPLIRTFPF-------------SLQHICRTVICNCTTYDGI
.:: .: : : :.: :::..:: :: . : : :
XP_016 IEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLI
460 470 480 490 500 510
410 420 430 440
pF1KB8 DALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
. ::.:..:: ::.: ::
XP_016 QKLPLPNKMKDYLQEKHY
520 530
>>XP_016881575 (OMIM: 605118) PREDICTED: suppressor of c (535 aa)
initn: 341 init1: 200 opt: 232 Z-score: 252.0 bits: 56.0 E(85289): 2.7e-07
Smith-Waterman score: 319; 36.9% identity (60.7% similar) in 168 aa overlap (271-424:369-535)
250 260 270 280 290 300
pF1KB8 SRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALL
: :. .: .. .. ::: . .. ::. :
XP_016 SMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKL
340 350 360 370 380 390
310 320 330 340 350 360
pF1KB8 EGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGL
. :.:.::.:::... ::.:.::: ....::.:::. : ::: ..: : .:. :
XP_016 ANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSF-YEQPDVEGHTSIVDL
400 410 420 430 440 450
370 380 390 400
pF1KB8 LEH-YKDPSACMFFEPLLSTPLIRTFPF-------------SLQHICRTVICNCTTYDGI
.:: .: : : :.: :::..:: :: . : : :
XP_016 IEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLI
460 470 480 490 500 510
410 420 430 440
pF1KB8 DALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
. ::.:..:: ::.: ::
XP_016 QKLPLPNKMKDYLQEKHY
520 530
440 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:55:09 2016 done: Fri Nov 4 15:55:11 2016
Total Scan time: 8.230 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]