Result of FASTA (omim) for
pF1KB8817
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8817, 381 aa
1>>>pF1KB8817 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7437+/-0.000484; mu= 20.0253+/- 0.031
mean_var=107.0275+/-28.303, 0's: 0 Z-trim(109.5): 688 B-trim: 920 in 1/52
Lambda= 0.123973
statistics sampled from 16817 (17648) to 16817 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.562), E-opt: 0.2 (0.207), width: 16
Scan time: 7.800
The best scores are: opt bits E(85289)
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 2478 454.8 1.5e-127
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 2478 454.8 1.5e-127
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 2478 454.8 1.5e-127
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 695 135.9 1.5e-31
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 618 122.2 2.2e-27
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 586 116.5 1.1e-25
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 578 115.0 3e-25
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 578 115.0 3e-25
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 578 115.0 3e-25
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 574 114.3 4.8e-25
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 574 114.3 4.8e-25
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 574 114.3 4.8e-25
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 574 114.3 4.8e-25
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 574 114.3 4.8e-25
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 574 114.3 4.8e-25
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 540 108.1 2.9e-23
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 530 106.4 1.1e-22
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 530 106.4 1.1e-22
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 529 106.2 1.2e-22
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 528 106.1 1.5e-22
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 528 106.2 1.6e-22
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 526 105.7 1.8e-22
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 525 105.6 2.2e-22
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 506 102.2 2.3e-21
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 491 99.5 1.5e-20
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387) 482 97.8 4.4e-20
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 476 96.8 9.2e-20
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 475 96.6 1e-19
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 462 94.3 5.4e-19
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 436 89.7 1.4e-17
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 434 89.3 1.8e-17
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 434 89.3 1.8e-17
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 434 89.4 2e-17
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 430 88.5 2.8e-17
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 430 88.6 2.9e-17
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 430 88.6 2.9e-17
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 430 88.6 2.9e-17
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 430 88.6 3e-17
NP_006165 (OMIM: 602001) neuropeptide Y receptor t ( 445) 426 87.9 5e-17
XP_011530319 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 426 87.9 5e-17
NP_001304021 (OMIM: 602001) neuropeptide Y recepto ( 445) 426 87.9 5e-17
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445) 426 87.9 5e-17
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 426 87.9 5e-17
XP_016863744 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 426 87.9 5e-17
XP_011530317 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 426 87.9 5e-17
XP_016863745 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 426 87.9 5e-17
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 425 87.6 5.1e-17
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 425 87.7 5.3e-17
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 422 87.2 8.1e-17
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 422 87.2 8.3e-17
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 2478 init1: 2478 opt: 2478 Z-score: 2410.9 bits: 454.8 E(85289): 1.5e-127
Smith-Waterman score: 2478; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KB8 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
310 320 330 340 350 360
370 380
pF1KB8 KNLEVRKNSGPNDSFTEATNV
:::::::::::::::::::::
XP_005 KNLEVRKNSGPNDSFTEATNV
370 380
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 2478 init1: 2478 opt: 2478 Z-score: 2410.9 bits: 454.8 E(85289): 1.5e-127
Smith-Waterman score: 2478; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KB8 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
310 320 330 340 350 360
370 380
pF1KB8 KNLEVRKNSGPNDSFTEATNV
:::::::::::::::::::::
XP_005 KNLEVRKNSGPNDSFTEATNV
370 380
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 2478 init1: 2478 opt: 2478 Z-score: 2410.9 bits: 454.8 E(85289): 1.5e-127
Smith-Waterman score: 2478; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KB8 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
310 320 330 340 350 360
370 380
pF1KB8 KNLEVRKNSGPNDSFTEATNV
:::::::::::::::::::::
NP_000 KNLEVRKNSGPNDSFTEATNV
370 380
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 665 init1: 227 opt: 695 Z-score: 687.6 bits: 135.9 E(85289): 1.5e-31
Smith-Waterman score: 695; 35.9% identity (68.4% similar) in 329 aa overlap (30-352:41-362)
10 20 30 40 50
pF1KB8 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLI-EVQVVLILAYC
: .: : ..: .:. ... ...: :
NP_004 VSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTP--FQSLQLVHQLKGLIVLLYS
20 30 40 50 60
60 70 80 90 100 110
pF1KB8 SIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE-WK
....:..:: :.. :. . . ...::::.:.:::..:.:. : :.:.::.:.. . :
NP_004 VVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 MGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISA
.: ::::: . : ..: ::..:::.::.::. .:. :. .:: :.: . :..::
NP_004 FGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISF
.:: : :. . .:. : .. : : : ..:.. .:. . ::. :.::: .: .
NP_004 VLALPAAVHTYH--VELKPH-DVRLCEEFWGSQERQ--RQLYAWGLLLVTYLLPLLVILL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 SYTRIWSKLKNHVSPGAAN----DHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDI
::.:. ::.:.: :: .. : . ::..: .:: ::::::: :::::.:.: :.
NP_004 SYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 DSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEV
: ...: . :. . : .:: :. ::..:.:.....:. . . . : : :..
NP_004 DPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQN
310 320 330 340 350 360
360 370 380
pF1KB8 SVTFKAKKNLEVRKNSGPNDSFTEATNV
NP_004 MTVSVVI
370
>>NP_057624 (OMIM: 605569) probable G-protein coupled re (423 aa)
initn: 485 init1: 359 opt: 618 Z-score: 612.6 bits: 122.2 E(85289): 2.2e-27
Smith-Waterman score: 618; 35.6% identity (69.6% similar) in 303 aa overlap (49-344:70-365)
20 30 40 50 60 70
pF1KB8 VEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKF
:...::.:: ::.....:: :: ::..:
NP_057 HFFSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKN
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB8 KSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVST
. :...:..::.::::::.... : ::::. . . : .: .::. .:: ...::.
NP_057 QRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSA
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB8 ITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDF
.:::.::.:::. :.. :. .:: . . :.. : ...... : :: .. .. :.
NP_057 LTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB8 EIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK--NHVSPGAAN
: .: : ... .:.....::.::: ::: .:.:. .:: : .. ...
NP_057 VRSLCLPDFP-EPADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTE
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB8 DHYHQRRQK--TTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA
... ::.: : :::. :::.::. :.::. . : ..:.: .. . .. .:: .:
NP_057 QYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKV--IRTNNALYFAFHWFA
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB8 MCSTFANPLLYGWMNSNYR---KAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGP
: :: ::..: :.: :.: ::.:: :..
NP_057 MSSTCYNPFIYCWLNENFRIELKALLSM--CQRPPKPQEDRPPSPVPSFRVAWTEKNDGQ
340 350 360 370 380 390
380
pF1KB8 NDSFTEATNV
NP_057 RAPLANNLLPTSQLQSGKTDLSSVEPIVTMS
400 410 420
>>NP_001049 (OMIM: 162323) substance-P receptor isoform (407 aa)
initn: 444 init1: 263 opt: 586 Z-score: 581.8 bits: 116.5 E(85289): 1.1e-25
Smith-Waterman score: 586; 30.4% identity (62.6% similar) in 342 aa overlap (31-366:10-345)
10 20 30 40 50
pF1KB8 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEV--QVVL-ILAY
.: :. . . ..... :.:: ::
NP_001 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAY
10 20 30
60 70 80 90 100 110
pF1KB8 CSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWK
:.. .:.:: .:. ... : ::::::.:..::: :. . .. ..::.. .::
NP_001 TVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB8 MGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISA
.: :.. . :: .: ..:..:.::. :.. :. ..: . ..: . : ..
NP_001 YGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLAL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 LLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISF
::: : . :: : .:. :.: .:: . ..:: :: . ...: ::: .:..
NP_001 LLAFPQGY---YSTTETMPSR--VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB8 SYTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDID
.:: . : :: ..:.::.. ..:..::.. :: .::. :::.: : : :.
NP_001 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB8 SQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVS
.. : . .. .. .:: ::. ::..: .:. .: .: :::: ..: : .
NP_001 PDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYE-G
280 290 300 310 320 330
360 370 380
pF1KB8 VTFKAKKNLEVRKNSGPNDSFTEATNV
. .:. . :...
NP_001 LEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSK
340 350 360 370 380 390
>>XP_005263088 (OMIM: 162641) PREDICTED: neuropeptide Y (384 aa)
initn: 539 init1: 353 opt: 578 Z-score: 574.3 bits: 115.0 E(85289): 3e-25
Smith-Waterman score: 585; 30.7% identity (65.2% similar) in 342 aa overlap (53-374:43-381)
30 40 50 60 70 80
pF1KB8 GPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMR
: ::: ..:.::: :: .: ...: : ::
XP_005 SVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMR
20 30 40 50 60 70
90 100 110 120 130 140
pF1KB8 TVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLT
.:::..:.::. .:::: .:::::..:::: .: .: ..:.: :..: ... :: ..:.
XP_005 NVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLV
80 90 100 110 120 130
150 160 170 180 190
pF1KB8 VIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFR-----EYSLIEIIPD
.::..::. :. . ..: ... :.. : ... . :. :.. .. . .
XP_005 LIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAY
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB8 FEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK--NHVSPGAA
. .: ...:.. . . :. :.. : :: .: . : .:. .:: :..
XP_005 KDKYVCFDQFPSDSHRLS---YTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMR
200 210 220 230 240
260 270 280 290 300 310
pF1KB8 NDHYHQRRQKTTK-MLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA
...:.. . : . ::. .::.::: :::: :. . : . :.. ...:.: . :. :
XP_005 DNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTA
250 260 270 280 290 300
320 330 340 350 360
pF1KB8 MCSTFANPLLYGWMNSNYRKAFLSAFR-CEQR----------LDAIHSEVSVT-FKAKKN
: :: .::..::..:.:... . : :. : ....:..:: : .: .
XP_005 MISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASP
310 320 330 340 350 360
370 380
pF1KB8 LEVRKNSGPNDSFTEATNV
. .: .. .:.
XP_005 VAFKKINNNDDNEKI
370 380
>>XP_011530312 (OMIM: 162641) PREDICTED: neuropeptide Y (384 aa)
initn: 539 init1: 353 opt: 578 Z-score: 574.3 bits: 115.0 E(85289): 3e-25
Smith-Waterman score: 585; 30.7% identity (65.2% similar) in 342 aa overlap (53-374:43-381)
30 40 50 60 70 80
pF1KB8 GPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMR
: ::: ..:.::: :: .: ...: : ::
XP_011 SVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMR
20 30 40 50 60 70
90 100 110 120 130 140
pF1KB8 TVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLT
.:::..:.::. .:::: .:::::..:::: .: .: ..:.: :..: ... :: ..:.
XP_011 NVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLV
80 90 100 110 120 130
150 160 170 180 190
pF1KB8 VIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFR-----EYSLIEIIPD
.::..::. :. . ..: ... :.. : ... . :. :.. .. . .
XP_011 LIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAY
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB8 FEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK--NHVSPGAA
. .: ...:.. . . :. :.. : :: .: . : .:. .:: :..
XP_011 KDKYVCFDQFPSDSHRLS---YTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMR
200 210 220 230 240
260 270 280 290 300 310
pF1KB8 NDHYHQRRQKTTK-MLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA
...:.. . : . ::. .::.::: :::: :. . : . :.. ...:.: . :. :
XP_011 DNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTA
250 260 270 280 290 300
320 330 340 350 360
pF1KB8 MCSTFANPLLYGWMNSNYRKAFLSAFR-CEQR----------LDAIHSEVSVT-FKAKKN
: :: .::..::..:.:... . : :. : ....:..:: : .: .
XP_011 MISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASP
310 320 330 340 350 360
370 380
pF1KB8 LEVRKNSGPNDSFTEATNV
. .: .. .:.
XP_011 VAFKKINNNDDNEKI
370 380
>>NP_000900 (OMIM: 162641) neuropeptide Y receptor type (384 aa)
initn: 539 init1: 353 opt: 578 Z-score: 574.3 bits: 115.0 E(85289): 3e-25
Smith-Waterman score: 585; 30.7% identity (65.2% similar) in 342 aa overlap (53-374:43-381)
30 40 50 60 70 80
pF1KB8 GPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMR
: ::: ..:.::: :: .: ...: : ::
NP_000 SVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMR
20 30 40 50 60 70
90 100 110 120 130 140
pF1KB8 TVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLT
.:::..:.::. .:::: .:::::..:::: .: .: ..:.: :..: ... :: ..:.
NP_000 NVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLV
80 90 100 110 120 130
150 160 170 180 190
pF1KB8 VIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFR-----EYSLIEIIPD
.::..::. :. . ..: ... :.. : ... . :. :.. .. . .
NP_000 LIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAY
140 150 160 170 180 190
200 210 220 230 240 250
pF1KB8 FEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLK--NHVSPGAA
. .: ...:.. . . :. :.. : :: .: . : .:. .:: :..
NP_000 KDKYVCFDQFPSDSHRLS---YTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMR
200 210 220 230 240
260 270 280 290 300 310
pF1KB8 NDHYHQRRQKTTK-MLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIA
...:.. . : . ::. .::.::: :::: :. . : . :.. ...:.: . :. :
NP_000 DNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTA
250 260 270 280 290 300
320 330 340 350 360
pF1KB8 MCSTFANPLLYGWMNSNYRKAFLSAFR-CEQR----------LDAIHSEVSVT-FKAKKN
: :: .::..::..:.:... . : :. : ....:..:: : .: .
NP_000 MISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASP
310 320 330 340 350 360
370 380
pF1KB8 LEVRKNSGPNDSFTEATNV
. .: .. .:.
NP_000 VAFKKINNNDDNEKI
370 380
>>XP_011538238 (OMIM: 601790) PREDICTED: neuropeptide Y (375 aa)
initn: 570 init1: 286 opt: 574 Z-score: 570.6 bits: 114.3 E(85289): 4.8e-25
Smith-Waterman score: 586; 32.3% identity (61.2% similar) in 371 aa overlap (24-371:15-374)
10 20 30 40 50 60
pF1KB8 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
:: :.. . : ..:.: .. .:
XP_011 MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIE
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
..::.:: .. :... : .:::..::::: .:.:. :: :.: .::.: : .:
XP_011 TVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
.::.. . : ..: :: ..:...::.::. :. : : ..: : : : :. .:.
XP_011 TLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLS
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 SPL-------AIF-REYS-LIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLP
:. .: ...: .:.. : :.:::.:: .. :.:. ::. : ::
XP_011 LPFLANSILENVFHKNHSKALEFLAD--KVVCTESWPLAHHR---TIYTTFLLLFQYCLP
180 190 200 210 220
240 250 260 270 280
pF1KB8 LGIISFSYTRIWSKLKNH---VSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQ
::.: :.::. :. . :. . . . .: .. .:: .::.::: :::::.:.
XP_011 LGFILVCYARIYRCLQRQGRVFHKGTYSLRAGHMKQVNV-VLVVMVVAFAVLWLPLHVFN
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 LAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLS-AFRCEQR--
: ... . . .::: : :..:: :: .::..::..:.:..: . . .. :.:
XP_011 SLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAP
290 300 310 320 330 340
350 360 370 380
pF1KB8 --------LDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
:...:.::: : .:.. :.:
XP_011 LEESEHLPLSTVHTEVS-----KGSLRLSGRSNPI
350 360 370
381 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:49:49 2016 done: Fri Nov 4 15:49:50 2016
Total Scan time: 7.800 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]