FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8713, 309 aa
  1>>>pF1KB8713 309 - 309 aa - 309 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.5997+/-0.000545; mu= -11.5035+/- 0.034
 mean_var=475.2821+/-102.996, 0's: 0 Z-trim(119.9): 42  B-trim: 1483 in 1/57
 Lambda= 0.058830
 statistics sampled from 34492 (34537) to 34492 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.405), width:  16
 Scan time:  7.210

The best scores are:                                      opt bits E(85289)
NP_689826 (OMIM: 610981) postacrosomal sheath WW d ( 309) 2139 195.6 1.1e-49
NP_036610 (OMIM: 606962) WW domain-binding protein ( 261)  495 55.9 9.9e-08
NP_001317428 (OMIM: 606962) WW domain-binding prot ( 216)  418 49.3 8.1e-06


>>NP_689826 (OMIM: 610981) postacrosomal sheath WW domai  (309 aa)
 initn: 2139 init1: 2139 opt: 2139  Z-score: 1013.0  bits: 195.6 E(85289): 1.1e-49
Smith-Waterman score: 2139; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)

               10        20        30        40        50        60
pF1KB8 MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 ITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 DAIEFAQLMVKAASAAARGFPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DAIEFAQLMVKAASAAARGFPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GYGAPPPGYGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPPAGYGAPPLGYGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GYGAPPPGYGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPPAGYGAPPLGYGA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 PPLGYGTPPLGYGAPPLGYGAPPAGNEGPPAGYRASPAGSGARPQESTAAQAPENEASLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PPLGYGTPPLGYGAPPLGYGAPPAGNEGPPAGYRASPAGSGARPQESTAAQAPENEASLP
              250       260       270       280       290       300

                
pF1KB8 SASSSQVHS
       :::::::::
NP_689 SASSSQVHS
                

>>NP_036610 (OMIM: 606962) WW domain-binding protein 2 i  (261 aa)
 initn: 467 init1: 293 opt: 495  Z-score: 259.8  bits: 55.9 E(85289): 9.9e-08
Smith-Waterman score: 509; 37.9% identity (59.2% similar) in 277 aa overlap (1-273:1-253)

               10        20        30        40        50        60
pF1KB8 MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIF
       ::.:..:.:.  :... : ::.:    .:::.: . ..  ..:.: : ::..:: :::::
NP_036 MALNKNHSEGG-GVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIF
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB8 ITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNG
       ... .  : : :::::: :: .  ..::::.::.::::..:   :::::.:..::.:  :
NP_036 LSKGK--DAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAG
      60          70        80        90       100       110       

              130        140       150       160       170         
pF1KB8 DAIEFAQLMVKAASAAARG-FPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPP
        ::::.: :...:: :.::  :  . .  .   : ::         :  : .  .:  ::
NP_036 GAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYP-------P--PVANGMYPCPP
       120       130       140       150                160        

     180          190       200       210       220       230      
pF1KB8 AGYGAPPPG---YGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPPAGYGAPPL
        ::  :::    : .::   ::  .:   ::     .:..   ::..    :.  .:   
NP_036 -GYPYPPPPPEFYPGPPMMDGA--MGYVQPPPPPYPGPME---PPVSGPDVPSTPAAEAK
       170       180         190       200          210       220  

        240       250       260       270       280       290      
pF1KB8 GYGAPPLGYGTPPLGYGAPPLGYGAPPAGNEGPPAGYRASPAGSGARPQESTAAQAPENE
       .  :   .: .:    : :   :   :...  ::  :                       
NP_036 AAEAAASAYYNP----GNPHNVY--MPTSQPPPPPYYPPEDKKTQ               
            230           240         250       260                

        300         
pF1KB8 ASLPSASSSQVHS

>>NP_001317428 (OMIM: 606962) WW domain-binding protein   (216 aa)
 initn: 429 init1: 273 opt: 418  Z-score: 225.5  bits: 49.3 E(85289): 8.1e-06
Smith-Waterman score: 439; 38.9% identity (61.6% similar) in 229 aa overlap (1-228:1-210)

               10        20        30        40        50        60
pF1KB8 MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIF
       ::.:..:.:.  :... : ::.:    .:::.: . ..  ..:.: : ::..:: :::::
NP_001 MALNKNHSEGG-GVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIF
               10         20        30        40        50         

               70        80        90       100       110       120
pF1KB8 ITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNG
       ... .  : : :::::: :: .  ..::::.::.::::..:   :::::.:..::.:  :
NP_001 LSKGK--DAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAG
      60          70        80        90       100       110       

              130       140       150       160       170       180
pF1KB8 DAIEFAQLMVKAASAAARGFPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPPA
        ::::.: :...::   . .:   . :  ..:: ::      .  :. :        : .
NP_001 GAIEFGQRMLQVASQ--EFYPGPPMMD--GAMG-YVQPPPPPYPGPMEP--------PVS
       120       130         140          150       160            

               190       200       210       220       230         
pF1KB8 GYGAPP-PGYGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPPAGYGAPPLGYG
       :  .:  :.  :  :  .:.   : : : .    :.    ::  :  ::           
NP_001 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYM-PTSQPPPPPYY--PPEDKKTQ     
          170       180       190        200         210           

     240       250       260       270       280       290         
pF1KB8 APPLGYGTPPLGYGAPPLGYGAPPAGNEGPPAGYRASPAGSGARPQESTAAQAPENEASL




309 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:49:29 2016 done: Fri Nov  4 14:49:30 2016
 Total Scan time:  7.210 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]